Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy

by Esslinger U., Garnier S., Korniat A., Proust C., Kararigas G., Müller-Nurasyid M., Empana J.-P., Morley M.P., Perret C., Stark K., Bick A.G., Prasad S.K., Kriebel J., Li J., Tiret L., Strauch K., O'Regan D.P., Marguiles K.B., Seidman J.G., Boutouyrie P., Lacolley P., Jouven X., Hengstenberg C., Komajda M., Hakonarson H., Isnard R., Arbustini E., Grallert H., Cook S.A., Seidman C.E., Regitz-Zagrosek V., Cappola T.P., Charron P., Cambien F., Villard E.
Published 2019

A genome-wide association meta-analysis of diarrhoeal disease in young children identifies FUT2 locus and provides plausible biological pathways

by Bustamante, M., Standl, M., Bassat, Q., Vilor-Tejedor, N., Medina-Gomez, C., Bonilla, C., Ahluwalia, T.S., Bacelis, J., Bradfield, J.P., Tiesler, C.M., Rivadeneira, F., Ring, S., Vissing, N.H., Fink, N.R., Jugessur, A., Mentch, F.D., Ballester, F., Kriebel, J., Kiefte, J.C., Wolsk, H.M., Llop, S., Thiering, E., Beth, S.A., Timpson, N.J., Andersen, J., Schulz, H., Jaddoe, V.W., Evans, D.M., Waage, J., Hakonarson, H., Grant, S.F., Jacobsson, B., Bønnelykke, K., Bisgaard, H.l., Davey Smith, G., Moll, H.A., Heinrich, J., Estivill, X., Sunyer, J.
Published 2016

A genome-wide association meta-analysis of diarrhoeal disease in young children identifies FUT2 locus and provides plausible biological pathways

by Bustamante, M., Standl, M., Bassat, Q., Vilor-Tejedor, N., Medina-Gomez, C., Bonilla, C., Ahluwalia, T.S., Bacelis, J., Bradfield, J.P., Tiesler, C.M.T., Rivadeneira, F., Ring, S., Vissing, N.H., Fink, N.R., Jugessur, A., Mentch, F.D., Ballester, F., Kriebel, J., Kiefte-de Jong, J.C., Wolsk, H.M., Llop, S., Thiering, E., Beth, S.A., Timpson, N.J., Andersen, J., Schulz, H., Jaddoe, V.W.V., Evans, D.M., Waage, J., Hakonarson, H., Grant, S.F.A., Jacobsson, B., Bonnelykke, K., Bisgaard, H., Smith, G.D., Moll, H.A., Heinrich, J., Estivill, X., Sunyer, J.
Published 2016

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

by Wahl, S., Drong, A., Lehne, B., Loh, M., Scott, W.R., Kunze, S., Tsai, P.C., Ried, J.S., Zhang, W.H., Yang, Y.W., Tan, S.L., Fiorito, G., Franke, L., Guarrera, S., Kasela, S., Kriebel, J., Richmond, R.C., Adamo, M., Afzal, U., Ala-Korpela, M., Albetti, B., Ammerpohl, O., Apperley, J.F., Beekman, M., Bertazzi, P.A., Black, S.L., Blancher, C., Bonder, M.J., Brosch, M., Carstensen-Kirberg, M., Craen, A.J.M. de, Lusignan, S. de, Dehghan, A., Elkalaawy, M., Fischer, K., Franco, O.H., Gaunt, T.R., Hampe, J., Hashemi, M., Isaacs, A., Jenkinson, A., Jha, S., Kato, N., Krogh, V., Laffan, M., Meisinger, C., Meitinger, T., Mok, Z.Y., Motta, V., Ng, H.K., Nikolakopoulou, Z., Nteliopoulos, G., Panico, S., Pervjakova, N., Prokisch, H., Rathmann, W., Roden, M., Rota, F., Rozario, M.A., Sandling, J.K., Schafmayer, C., Schramm, K., Siebert, R., Slagboom, P.E., Soininen, P., Stolk, L., Strauch, K., Tai, E.S., Tarantini, L., Thorand, B., Tigchelaar, E.F., Tumino, R., Uitterlinden, A.G., Duijn, C. van, Meurs, J.B.J. van, Vineis, P., Wickremasinghe, A.R., Wijmenga, C., Yang, T.P., Yuan, W., Zhernakova, A., Batterham, R.L., Smith, G.D., Deloukas, P., Heijmans, B.T., Herder, C., Hofman, A., Lindgren, C.M., Milani, L., Harst, P. van der, Peters, A., Illig, T., Relton, C.L., Waldenberger, M., Jarvelin, M.R., Bollati, V., Soong, R., Spector, T.D., Scott, J., McCarthy, M.I., Elliott, P., Bell, J.T., Matullo, G., Gieger, C., Kooner, J.S., Grallert, H., Chambers, J.C.
Published 2017

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

by Wahl, S., Drong, A., Lehne, B., Loh, M., Scott, W.R., Kunze, S., Tsai, P.C., Ried, J.S., Zhang, W.H., Yang, Y.W., Tan, S.L., Fiorito, G., Franke, L., Guarrera, S., Kasela, S., Kriebel, J., Richmond, R.C., Adamo, M., Afzal, U., Ala-Korpela, M., Albetti, B., Ammerpohl, O., Apperley, J.F., Beekman, M., Bertazzi, P.A., Black, S.L., Blancher, C., Bonder, M.J., Brosch, M., Carstensen-Kirberg, M., Craen, A.J.M. de, Lusignan, S. de, Dehghan, A., Elkalaawy, M., Fischer, K., Franco, O.H., Gaunt, T.R., Hampe, J., Hashemi, M., Isaacs, A., Jenkinson, A., Jha, S., Kato, N., Krogh, V., Laffan, M., Meisinger, C., Meitinger, T., Mok, Z.Y., Motta, V., Ng, H.K., Nikolakopoulou, Z., Nteliopoulos, G., Panico, S., Pervjakova, N., Prokisch, H., Rathmann, W., Roden, M., Rota, F., Rozario, M.A., Sandling, J.K., Schafmayer, C., Schramm, K., Siebert, R., Slagboom, P.E., Soininen, P., Stolk, L., Strauch, K., Tai, E.S., Tarantini, L., Thorand, B., Tigchelaar, E.F., Tumino, R., Uitterlinden, A.G., Duijn, C. van, Meurs, J.B.J. van, Vineis, P., Wickremasinghe, A.R., Wijmenga, C., Yang, T.P., Yuan, W., Zhernakova, A., Batterham, R.L., Smith, G.D., Deloukas, P., Heijmans, B.T., Herder, C., Hofman, A., Lindgren, C.M., Milani, L., Harst, P. van der, Peters, A., Illig, T., Relton, C.L., Waldenberger, M., Jarvelin, M.R., Bollati, V., Soong, R., Spector, T.D., Scott, J., McCarthy, M.I., Elliott, P., Bell, J.T., Matullo, G., Gieger, C., Kooner, J.S., Grallert, H., Chambers, J.C.
Published 2017

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

by Mahajan, A., Taliun, D., Thurner, M., Robertson, N.R., Torres, J.M., Rayner, N.W., Payne, A.J., Steinthorsdottir, V., Scott, R.A., Grarup, N., Cook, J.P., Schmidt, E.M., Wuttke, M., Sarnowski, C., Magill, R., Nano, J., Gieger, C., Trompet, S., Lecoeur, C., Preuss, M.H., Prins, B.P., Guo, X.Q., Bielak, L.F., Below, J.E., Bowden, D.W., Chambers, J.C., Kim, Y.J., Ng, M.C.Y., Petty, L.E., Sim, X.L., Zhang, W.H., Bennett, A.J., Bork-Jensen, J., Brummett, C.M., Canouil, M., Kardt, K.U.E., Fischer, K., Kardia, S.L.R., Kronenberg, F., Lall, K., Liu, C.T., Locke, A.E., Luan, J.A., Ntalla, L., Nylander, V., Schonherr, S., Schurmann, C., Yengo, L., Bottinger, E.P., Brandslund, I., Christensen, C., Dedoussis, G., Florez, J.C., Ford, I., France, O.H., Frayling, T.M., Giedraitis, V., Hackinger, S., Hattersley, A.T., Herder, C., Ikram, M.A., Ingelsson, M., Jorgensen, M.E., Jorgensen, T., Kriebel, J., Kuusisto, J., Ligthart, S., Lindgren, C.M., Linneberg, A., Lyssenko, V., Mamakou, V., Meitinger, T., Mohlke, K.L., Morris, A.D., Nadkarni, G., Pankow, J.S., Peters, A., Sattar, N., Stancakova, A., Strauch, K., Taylor, K.D., Thorand, B., Thorleifsson, G., Thorsteinsdottir, U., Tuomilehto, J., Witte, D.R., Dupuis, J., Peyser, P.A., Zeggini, E., Loos, R.J.F., Froguel, P., Ingelsson, E., Lind, L., Groop, L., Laakso, M., Collins, F.S., Jukema, J.W., Palmer, C.N.A., Grallert, H., Metspalu, A., Dehghan, A., Kottgen, A., Abecasis, G.R., Meigs, J.B., Rotter, J.I., Marchini, J., Pedersen, O., Hansen, T., Langenberg, C., Wareham, N.J., Stefansson, K., Gloyn, A.L., Morris, A.P., Boehnke, M., McCarthy, M.I.
Published 2018

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease

by Webb, T.R., Erdmann, J., Stirrups, K.E., Stitziel, N.O., Masca, N.G.D., Jansen, H., Kanoni, S., Nelson, C.P., Ferrario, P.G., Konig, I.R., Eicher, J.D., Johnson, A.D., Hamby, S.E., Betsholtz, C., Ruusalepp, A., Franzen, O., Schadt, E.E., Bjorkegren, J.L.M., Weeke, P.E., Auer, P.L., Schick, U.M., Lu, Y.C., Zhang, H., Dube, M.P., Goel, A., Farrall, M., Peloso, G.M., Won, H.H., , R. do, Iperen, E. van, Kruppa, J., Mahajan, A., Scott, R.A., Willenborg, C., Braund, P.S., Capelleveen, J.C. van, Doney, A.S.F., Donnelly, L.A., Asselta, R., Merlini, P.A., Duga, S., Marziliano, N., Denny, J.C., Shaffer, C., El-Mokhtari, N.E., Franke, A., Heilmann, S., Hengstenberg, C., Hoffmann, P., Holmen, O.L., Hveem, K., Jansson, J.H., Jockel, K.H., Kessler, T., Kriebel, J., Laugwitz, K.L., Marouli, E., Martinelli, N., McCarthy, M.I., Zuydam, N.R. van, Meisinger, C., Esko, T., Mihailov, E., Escher, S.A., Alver, M., Moebus, S., Morris, A.D., Virtamo, J., Nikpay, M., Olivieri, O., Provost, S., AlQarawi, A., Robertson, N.R., Akinsansya, K.O., Reilly, D.F., Vogt, T.F., Yin, W., Asselbergs, F.W., Kooperberg, C., Jackson, R.D., Stahl, E., Muller-Nurasyid, M., Strauch, K., Varga, T.V., Waldenberger, M., Zeng, L.Y., Chowdhury, R., Salomaa, V., Ford, I., Jukema, J.W., Amouyel, P., Kontto, J., Nordestgaard, B.G., Ferrieres, J., Saleheen, D., Sattar, N., Surendran, P., Wagner, A., Young, R., Howson, J.M.M., Butterworth, A.S., Danesh, J., Ardissino, D., Bottinger, E.P., Erbel, R., Franks, P.W., Girelli, D., Hall, A.S., Hovingh, G.K., Kastrati, A., Lieb, W., Meitinger, T., Kraus, W.E., Shah, S.H., McPherson, R., Orho-Melander, M., Melander, O., Metspalu, A., Palmer, C.N.A., Peters, A., Rader, D.J., Reilly, M.P., Loos, R.J.F., Reiner, A.P., Roden, D.M., Tardif, J.C., Thompson, J.R., Wareham, N.J., Watkins, H., Willer, C.J., Samani, N.J., Schunkert, H., Deloukas, P., Kathiresan, S., Wellcome Trust Case Control, MORGAM Investigators, Myocardial Infarction Genetics
Published 2017

SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function

by Li, M., Li, Y., Weeks, O., Mijatovic, V., Teumer, A., Huffman, J.E., Tromp, G., Fuchsberger, C., Gorski, M., Lyytikainen, L.P., Nutile, T., Sedaghat, S., Sorice, R., Tin, A., Yang, Q., Ahluwalia, T.S., Arking, D.E., Bihlmeyer, N.A., Boger, C.A., Carroll, R.J., Chasman, D.I., Comelis, M.C., Dehghan, A., Faul, J.D., Feitosa, M.F., Gambaro, G., Gasparini, P., Giulianini, F., Heid, I., Huang, J.Y., Imboden, M., Jackson, A.U., Jeff, J., Jhun, M.A., Katz, R., Kifley, A., Kilpelainen, T., Kumar, A., Laakso, M., Li-Gao, R.F., Lohman, K., Lu, Y.C., Magi, R., Malerba, G., Mihailov, E., Mohlke, K.L., Mook-Kanamori, D.O., Robino, A., Ruderfer, D., Salvi, E., Schick, U.M., Schulz, C.A., Smith, A.V., Smith, J.A., Traglia, M., Yerges-Armstrong, L.M., Zhao, W., Goodarzi, M.O., Kraja, A.T., Liu, C.Y., Wessel, J., Boerwinkle, E., Borecki, I.B., Bork-Jensen, J., Bottinger, E.P., Braga, D., Brandslund, I., Brody, J.A., Campbell, A., Carey, D.J., Christensen, C., Coresh, J., Crook, E., Curhan, G.C., Cusi, D., Boer, I.H. de, Vries, A.P.J. de, Denny, J.C., Devuyst, O., Dreisbach, A.W., Endlich, K., Esko, T., Franco, O.H., Fulop, T., Gerhard, G.S., Glumer, C., Gottesman, O., Grarup, N., Gudnason, V., Hansen, T., Harris, T.B., Hayward, C., Hocking, L., Hofman, A., Hu, F.B., Husemoen, L.L.N., Jackson, R.D., Jorgensen, T., Jorgensen, M.E., Kahonen, M., Kardia, S.L.R., Konig, W., Kooperberg, C., Kriebel, J., Launer, L.J., Lauritzen, T., Lehtimaki, T., Levy, D., Linksted, P., Linneberg, A., Liu, Y.M., Loos, R.J.F., Lupo, A., Meisinger, C., Melander, O., Metspalu, A., Mitchell, P., Nauck, M., Nurnberg, P., Orho-Melander, M., Parsa, A., Pedersen, O., Peters, A., Peters, U., Polasek, O., Porteous, D., Probst-Hensch, N.M., Psaty, B.M., Qi, L., Raitakari, O.T., Reiner, A.P., Rettig, R., Ridker, P.M., Rivadeneira, F., Rossouw, J.E., Schmidt, F., Siscovick, D., Soranzo, N., Strauch, K., Toniolo, D., Turner, S.T., Uitterlinden, A.G., Ulivi, S., Velayutham, D., Volker, U., Volzke, H., Waldenberger, M., Wang, J.J., Weir, D.R., Witte, D., Kuivaniemi, H., Fox, C.S., Franceschini, N., Goessling, W., Kottgen, A., Chu, A.Y., CKDGen Consortium, CHARGE Glycemic-T2D Working Grp, CHARGE Blood Pressure Working Grp
Published 2017

Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity

by Yaghootkar, H., Zhang, Y.Y., Spracklen, C.N., Karaderi, T., Huang, L.O., Bradfield, J., Schurmann, C., Fine, R.S., Preuss, M.H., Kutalik, Z., Wittemans, L.B.L., Lu, Y.C., Metz, S., Willems, S.M., Li-Gao, R.F., Grarup, N., Wang, S., Molnos, S., Sandoval-Zarate, A.A., Nalls, M.A., Lange, L.A., Haesser, J., Guo, X.Q., Lyytikainen, L.P., Feitosa, M.F., Sitlani, C.M., Venturini, C., Mahajan, A., Kacprowski, T., Wang, C.R.A., Chasman, D.I., Amin, N., Broer, L., Robertson, N., Young, K.L., Allison, M., Auer, P.L., Bluher, M., Borja, J.B., Bork-Jensen, J., Carrasquilla, G.D., Christofidou, P., Demirkan, A., Doege, C.A., Garcia, M.E., Graff, M., Guo, K.Y., Hakonarson, H., Hong, J.Y., Chen, Y.D.I., Jackson, R., Jakupovic, H., Jousilahti, P., Justice, A.E., Kahonen, M., Kizer, J.R., Kriebel, J., LeDuc, C.A., Li, J., Lind, L., Luan, J.N., Mackey, D.A., Mangino, M., Mannisto, S., Carli, J.M.F., Medina-Gomez, C., Mook-Kanamori, D.O., Morris, A.P., Mutsert, R. de, Nauck, M., Prokic, I., Pennell, C.E., Pradhan, A.D., Psaty, B.M., Raitakari, O.T., Scott, R.A., Skaaby, T., Strauch, K., Taylor, K.D., Teumer, A., Uitterlinden, A.G., Wu, Y., Yao, J., Walker, M., North, K.E., Kovacs, P., Ikram, M.A., Duijn, C.M. van, Ridker, P.M., Lye, S., Homuth, G., Ingelsson, E., Spector, T.D., McKnight, B., Province, M.A., Lehtimaki, T., Adair, L.S., Rotter, J.I., Reiner, A.P., Wilson, J.G., Harris, T.B., Ripatti, S., Grallert, H., Meigs, J.B., Salomaa, V., Hansen, T., Dijk, K.W. van, Wareham, N.J., Grant, S.F.A., Langenberg, C., Frayling, T.M., Lindgren, C.M., Mohlke, K.L., Leibel, R.L., Loos, R.J.F., Kilpelainen, T.O.
Published 2020

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

by Christophersen, I.E., Rienstra, M., Roselli, C., Yin, X.Y., Geelhoed, B., Barnard, J., Lin, H.H., Arking, D.E., Smith, A.V., Albert, C.M., Chaffin, M., Tucker, N.R., Li, M.L., Klarin, D., Bihlmeyer, N.A., Low, S.K., Weeke, P.E., Muller-Nurasyid, M., Smith, J.G., Brody, J.A., Niemeijer, M.N., Dorr, M., Trompet, S., Huffman, J., Gustafsson, S., Schurmann, C., Kleber, M.E., Lyytikainen, L.P., Seppala, I., Malik, R., Horimoto, A.R.V.R., Perez, M., Sinisalo, J., Aeschbacher, S., Theriault, S., Yao, J., Radmanesh, F., Weiss, S., Teumer, A., Choi, S.H., Weng, L.C., Clauss, S., Deo, R., Rader, D.J., Shah, S.H., Sun, A., Hopewell, J.C., Debette, S., Chauhan, G., Yang, Q., Worrall, B.B., Pare, G., Kamatani, Y., Hagemeijer, Y.P., Verweij, N., Siland, J.E., Kubo, M., Smith, J.D., Wagoner, D.R. van, Bis, J.C., Perz, S., Psaty, B.M., Ridker, P.M., Magnani, J.W., Harris, T.B., Launer, L.J., Shoemaker, M.B., Padmanabhan, S., Haessler, J., Bartz, T.M., Waldenberger, M., Lichtner, P., Arendt, M., Krieger, J.E., Kahonen, M., Risch, L., Mansur, A.J., Peters, A., Smith, B.H., Lind, L., Scott, S.A., Lu, Y.C., Bottinger, E.B., Hernesniemi, J., Lindgren, C.M., Wong, J.A., Huang, J., Eskola, M., Morris, A.P., Ford, I., Reiner, A.P., Delgado, G., Chen, L.Y., Chen, Y.D.I., Sandhu, R.K., Li, M., Boerwinkle, E., Eisele, L., Lannfelt, L., Rost, N., Anderson, C.D., Taylor, K.D., Campbell, A., Magnusson, P.K., Porteous, D., Hocking, L.J., Vlachopoulou, E., Pedersen, N.L., Nikus, K., Orho-Melander, M., Hamsten, A., Heeringa, J., Denny, J.C., Kriebel, J., Darbar, D., Newton-Cheh, C., Shaffer, C., Macfarlane, P.W., Heilmann-Heimbach, S., Almgren, P., Huang, P.L., Sotoodehnia, N., Soliman, E.Z., Uitterlinden, A.G., Hofman, A., Franco, O.H., Volker, U., Jockel, K.H., Sinner, M.F., Lin, H.J., Guo, X.Q., Dichgans, M., Ingelsson, E., Kooperberg, C., Melander, O., Loos, R.J.F., Laurikka, J., Conen, D., Rosand, J., Harst, P. van der, Lokki, M.L., Kathiresan, S., Pereira, A., Jukema, J.W., Hayward, C., Rotter, J.I., Marz, W., Lehtimaki, T., Stricker, B.H., Chung, M.K., Felix, S.B., Gudnason, V., Alonso, A., Roden, D.M., Kaab, S., Chasman, D.I., Heckbert, S.R., Benjamin, E.J., Tanaka, T., Lunetta, K.L., Lubitz, S.A., Ellinor, P.T., METASTROKE Consortium ISGC, Neurology Working Grp CHARGE, AFGen Consortium
Published 2017

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

by Kilpelainen, T.O., Carli, J.F.M., Skowronski, A.A., Sun, Q., Kriebel, J., Feitosa, M.F., Hedman, A.K., Drong, A.W., Hayes, J.E., Zhao, J.H., Pers, T.H., Schick, U., Grarup, N., Kutalik, Z., Trompet, S., Mangino, M., Kristiansson, K., Beekman, M., Lyytikainen, L.P., Eriksson, J., Henneman, P., Lahti, J., Tanaka, T., Luan, J.A., Greco, F. del, Pasko, D., Renstrom, F., Willems, S.M., Mahajan, A., Rose, L.M., Guo, X.Q., Liu, Y.M., Kleber, M.E., Perusse, L., Gaunt, T., Ahluwalia, T.S., Sung, Y.J., Ramos, Y.F., Amin, N., Amuzu, A., Barroso, I., Bellis, C., Blangero, J., Buckley, B.M., Bohringer, S., Chen, Y.D.I., Craen, A.J.N. de, Crosslin, D.R., Dale, C.E., Dastani, Z., Day, F.R., Deelen, J., Delgado, G.E., Demirkan, A., Finucane, F.M., Ford, I., Garcia, M.E., Gieger, C., Gustafsson, S., Hallmans, G., Hankinson, S.E., Havulinna, A.S., Herder, C., Hernandez, D., Hicks, A.A., Hunter, D.J., Illig, T., Ingelsson, E., Ioan-Facsinay, A., Jansson, J.O., Jenny, N.S., Jorgensen, M.E., Jorgensen, T., Karlsson, M., Koenig, W., Kraft, P., Kwekkeboom, J., Laatikainen, T., Ladwig, K.H., LeDuc, C.A., Lowe, G., Lu, Y.C., Marques-Vidal, P., Meisinger, C., Menni, C., Morris, A.P., Myers, R.H., Mannisto, S., Nalls, M.A., Paternoster, L., Peters, A., Pradhan, A.D., Rankinen, T., Rasmussen-Torvik, L.J., Rathmann, W., Rice, T.K., Richards, J.B., Ridker, P.M., Sattar, N., Savage, D.B., Soderberg, S., Timpson, N.J., Vandenput, L., Heemst, D. van, Uh, H.W., Vohl, M.C., Walker, M., Wichmann, H.E., Widen, E., Wood, A.R., Yao, J., Zeller, T., Zhang, Y.Y., Meulenbelt, I., Kloppenburg, M., Astrup, A., Sorensen, T.I.A., Sarzynski, M.A., Rao, D.C., Jousilahti, P., Vartiainen, E., Hofman, A., Rivadeneira, F., Uitterlinden, A.G., Kajantie, E., Osmond, C., Palotie, A., Eriksson, J.G., Heliovaara, M., Knekt, P.B., Koskinen, S., Jula, A., Perola, M., Huupponen, R.K., Viikari, J.S., Kahonen, M., Lehtimaki, T., Raitakari, O.T., Mellstrom, D., Lorentzon, M., Casas, J.P., Bandinelli, S., Marz, W., Isaacs, A., Dijk, K.W. van, Duijn, C.M. van, Harris, T.B., Bouchard, C., Allison, M.A., Chasman, D.I., Ohlsson, C., Lind, L., Scott, R.A., Langenberg, C., Wareham, N.J., Ferrucci, L., Frayling, T.M., Pramstaller, P.P., Borecki, I.B., Waterworth, D.M., Bergmann, S., Waeber, G., Vollenweider, P., Vestergaard, H., Hansen, T., Pedersen, O., Hu, F.B., Slagboom, P.E., Grallert, H., Spector, T.D., Jukema, J.W., Klein, R.J., Schadt, E.E., Franks, P.W., Lindgren, C.M., Leibel, R.L., Loos, R.J.F.
Published 2016

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

by Spracklen, C.N., Karaderi, T., Yaghootkar, H., Schurmann, C., Fine, R.S., Kutalik, Z., Preuss, M.H., Lu, Y.C., Wittemans, L.B.L., Adair, L.S., Allison, M., Amin, N., Auer, P.L., Bartz, T.M., Bluher, M., Boehnke, M., Borja, J.B., Bork-Jensen, J., Broer, L., Chasman, D.I., Chen, Y.D.I., Chirstofidou, P., Demirkan, A., Duijn, C.M. van, Feitosa, M.F., Garcia, M.E., Graff, M., Grallert, H., Grarup, N., Guo, X.Q., Haesser, J., Hansen, T., Harris, T.B., Highland, H.M., Hong, J., Ikram, M.A., Ingelsson, E., Jackson, R., Jousilahti, P., Kahonen, M., Kizer, J.R., Kovacs, P., Kriebel, J., Laakso, M., Lange, L.A., Lehtimaki, T., Li, J., Ruifang, L.G., Lind, L., Luan, J.A., Lyytikainen, L.P., MacGregor, S., Mackey, D.A., Mahajan, A., Mangino, M., Mannisto, S., McCarthy, M.I., McKnight, B., Medina-Gomez, C., Meigs, J.B., Molnos, S., Mook-Kanamori, D., Morris, A.P., Mutsert, R. de, Nalls, M.A., Nedeljkovic, I., North, K.E., Pennell, C.E., Pradhan, A.D., Province, M.A., Raitakari, O.T., Raulerson, C.K., Reiner, A.P., Ridker, P.M., Ripatti, S., Roberston, N., Rotter, J.I., Salomaa, V., Sandoval-Zarate, A.A., Sitlani, C.M., Spector, T.D., Strauch, K., Stumvoll, M., Taylor, K.D., Thuesen, B., Tonjes, A., Uitterlinden, A.G., Venturini, C., Walker, M., Wang, C.A., Wang, S., Wareham, N.J., Willems, S.M., Dijk, K.W. van, Wilson, J.G., Wu, Y., Yao, J., Young, K.L., Langenberg, C., Frayling, T.M., Kilpelainen, T.O., Lindgren, C.M., Loos, R.J.F., Mohlke, K.L.
Published 2019

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

by Mahajan, A., Wessel, J., Willems, S.M., Zhao, W., Robertson, N.R., Chu, A.Y., Gan, W., Kitajima, H., Taliun, D., Rayner, N.W., Guo, X.Q., Lu, Y.C., Li, M., Jensen, R.A., Hu, Y., Huo, S.F., Lohman, K.K., Zhang, W.H., Cook, J.P., Prins, B.P., Flannick, J., Grarup, N., Trubetskoy, V.V., Kravic, J., Kim, Y.J., Rybin, D.V., Yaghootkar, H., Muuller-Nurasyid, M., Meidtner, K., Li-Gao, R.F., Varga, T.V., Marten, J., Li, J., Smith, A.V., An, P., Ligthart, S., Gustafsson, S., Malerba, G., Demirkan, A., Tajes, J.F., Steinthorsdottir, V., Wuttke, M., Lecoeur, C., Preuss, M., Bielak, L.F., Graff, M., Highland, H.M., Justice, A.E., Liu, D.J., Marouli, E., Peloso, G.M., Warren, H.R., Afaq, S., Afzal, S., Ahlqvist, E., Almgren, P., Amin, N., Bang, L.B., Bertoni, A.G., Bombieri, C., Bork-Jensen, J., Brandslund, I., Brody, J.A., Burtt, N.P., Canouil, M., Chen, Y.D.I., Cho, Y.S., Christensen, C., Eastwood, S.V., Eckardt, K.U., Fischer, K., Gambaro, G., Giedraitis, V., Grove, M.L., Haan, H.G. de, Hackinger, S., Hai, Y., Han, S., Tybjaerg-Hansen, A., Hivert, M.F., Isomaa, B., Jager, S., Jorgensen, M.E., Jorgensen, T., Karajamaki, A., Kim, B.J., Kim, S.S., Koistinen, H.A., Kovacs, P., Kriebel, J., Kronenberg, F., Lall, K., Lange, L.A., Lee, J.J., Lehne, B., Li, H.X., Lin, K.H., Linneberg, A., Liu, C.T., Liu, J., Loh, M., Magi, R., Mamakou, V., McKean-Cowdin, R., Nadkarni, G., Neville, M., Nielsen, S.F., Ntalla, I., Peyser, P.A., Rathmann, W., Rice, K., Rich, S.S., Rode, L., Rolandsson, O., Schonherr, S., Selvin, E., Small, K.S., Stancakova, A., Surendran, P., Taylor, K.D., Teslovich, T.M., Thorand, B., Thorleifsson, G., Tin, A., Tonjes, A., Varbo, A., Witte, D.R., Wood, A.R., Yajnik, P., Yao, J., Yengo, L., Young, R., Amouyel, P., Boeing, H., Boerwinkle, E., Bottinger, E.P., Chowdhury, R., Collins, F.S., Dedoussis, G., Dehghan, A., Deloukas, P., Ferrario, M.M., Ferrieres, J., Florez, J.C., Frossard, P., Gudnason, V., Harris, T.B., Heckbert, S.R., Howson, J.M.M., Ingelsson, M., Kathiresan, S., Kee, F., Kuusisto, J., Langenberg, C., Launer, L.J., Lindgren, C.M., Mannisto, S., Meitinger, T., Melander, O., Mohlke, K.L., Moitry, M., Morris, A.D., Murray, A.D., Mutsert, R. de, Orho-Melander, M., Owen, K.R., Perola, M., Peters, A., Province, M.A., Rasheed, A., Ridker, P.M., Rivadineira, F., Rosendaal, F.R., Rosengren, A.H., Salomaa, V., Sheu, W.H.H., Sladek, R., Smith, B.H., Strauch, K., Uitterlinden, A.G., Varma, R., Willer, C.J., Bluher, M., Butterworth, A.S., Chambers, J.C., Chasman, D.I., Danesh, J., Duijn, C. van, Dupuis, J., Franco, O.H., Franks, P.W., Froguel, P., Grallert, H., Groop, L., Han, B.G., Hansen, T., Hattersley, A.T., Hayward, C., Ingelsson, E., Kardia, S.L.R., Karpe, F., Kooner, J.S., Kottgen, A., Kuulasmaa, K., Laakso, M., Lin, X., Lind, L., Liu, Y.M., Loos, R.J.F., Marchini, J., Metspalu, A., Mook-Kanamori, D., Nordestgaard, B.G., Palmer, C.N.A., Pankow, J.S., Pedersen, O., Psaty, B.M., Rauramaa, R., Sattar, N., Schulze, M.B., Soranzo, N., Spector, T.D., Stefansson, K., Stumvoll, M., Thorsteinsdottir, U., Tuomi, T., Tuomilehto, J., Wareham, N.J., Wilson, J.G., Zeggini, E., Scott, R.A., Barroso, I., Frayling, T.M., Goodarzi, M.O., Meigs, J.B., Boehnke, M., Saleheen, D., Morris, A.P., Rotter, J.I., McCarthy, M.I., ExomeBP Consortium, MAGIC Consortium, GIANT Consortium
Published 2018

Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus

by Mahajan A., SIM XUELING, Ng H.J., Manning A., Rivas M.A., Highland H.M., Locke A.E., Grarup N., Im H.K., Cingolani P., Flannick J., Fontanillas P., Fuchsberger C., Gaulton K.J., Teslovich T.M., Rayner N.W., Robertson N.R., Beer N.L., Rundle J.K., Bork-Jensen J., Ladenvall C., Blancher C., Buck D., Buck G., Burtt N.P., Gabriel S., Gjesing A.P., Groves C.J., Hollensted M., Huyghe J.R., Jackson A.U., Jun G., Justesen J.M., Mangino M., Murphy J., Neville M., Onofrio R., Small K.S., Stringham H.M., Syvänen A.-C., Trakalo J., Abecasis G., Bell G.I., Blangero J., Cox N.J., Duggirala R., Hanis C.L., Seielstad M., Wilson J.G., Christensen C., Brandslund I., Rauramaa R., Surdulescu G.L., Doney A.S.F., Lannfelt L., Linneberg A., Isomaa B., Tuomi T., Jørgensen M.E., Jørgensen T., Kuusisto J., Uusitupa M., Salomaa V., Spector T.D., Morris A.D., Palmer C.N.A., Collins F.S., Mohlke K.L., Bergman R.N., Ingelsson E., Lind L., Tuomilehto J., Hansen T., Watanabe R.M., Prokopenko I., Dupuis J., Karpe F., Groop L., Laakso M., Pedersen O., Florez J.C., Morris A.P., Altshuler D., Meigs J.B., Boehnke M., McCarthy M.I., Lindgren C.M., Gloyn A.L., Abboud H.E., Afzal U., Aguilar D., Arya R., Atzmon G., Aung T., Banks E., Barroso I., Barzilai N., Below J.E., Bharadwaj D., Blackwell T.W., Bonnycastle L.L., Bowden D., Carey J., Carneiro M.O., Chambers J.C., Chan E., Chan J., Chandak G.R., Chen P., Chen Y., Chen H., Cheng C.-Y., Chia K.S., Cho Y.S., Correa A., Curran J.E., Daly M.J., Day-Williams A.G., DeFronzo R.A., DePristo M., Donnelly P.J., Ebrahim S.B., Elliott P., Esko T., Fadista J., Farjoun Y., Farmer A.J., Farook V.S., Fennell T., Ferreira T., Fingerlin T., Forsén T., Fowler S.P., Franks P.W., Frayling T.M., Freedman B.I., Froguel P., Gamazon E.R., Gieger C., Glaser B., Go M.J., Goldstein J.I., Grallert H., Grant G., Green T., Griswold M., Hale D.E., Han B.-G., Hartl C., Hattersley A.T., Hicks P.J., Hodgkiss D., Horikoshi M., Hrabé de Angelis M., Hu C., Hu F.B., Huh I., Kamran Ikram M., Illig T., Jablonski K.A., Jenkinson C.P., Jia W., Kang H.M., Khor C.-C., Kim Y., Kim Y.J., Kim B.-J., Kinnunen L., Kooner J.S., Kravic J., Kriebel J., Kumar A., Kumar S., Kuulasmaa T., Kwon M.-S., Langenberg C., Lauritzen T., Lee S., Lee J., Lee J., Lee J.-Y., Lehman D.M., Lehne B., Levy J.C., Li J., Liang L., Lim W.Y., Lin K.-H., Liu J., Loh M., Ma R.C.W., Ma C., Mägi R., Maguire J., Maxwell T.J., McVean G., Meisinger C., Meitinger T., Melander O., Metspalu A., Mihailov E., Milani L., Moutsianas L., Müller-Nurasyid M., K. Musani S., Nagai Y., Narisu N., Neale B.M., Ng M.C.Y., Nilsson P., O'Rahilly S.P., Orho-Melander M., Owen K.R., Palmer N.D., Park T., Pasko D., Pearson R.D., Perry J.R.B., Peters A., Pollin T.I., Poplin R., Prabhakaran D., Puppala S., Purcell S., Qi L., Qi Q., Roden M., Rolandsson O., Rosengren A.H., Sandhu M., Schwarzmayr T., Scott L.J., Scott R.A., Scott J., Scott W.R., Sehmi J., Shakir K., Sladek R., Smith J.D., Stancáková A., Strauch K., Strom T.M., Swift A., Tai E.S., Tajes J.F., Tan S.-T., Tandon N., Taylor H.A., Jr., Teo Y.Y., Thameem F., Thorand B., van de Bunt M., Varga T.V., Walker M., Wareham N.J., Welch R.P., Wieland T., Wilson G., Sr., Wong T.Y., Wood A.R., Yoon J., Zeggini E., Zhang W.
Published 2018

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

by Day, F.R., Ruth, K.S., Thompson, D.J., Lunetta, K.L., Pervjakova, N., Chasman, D.I., Stolk, L., Finucane, H.K., Sulem, P., Bulik-Sullivan, B., Esko, T., Johnson, A.D., Elks, C.E., Franceschini, N., He, C.Y., Altmaier, E., Brody, J.A., Franke, L.L., Huffman, J.E., Keller, M.F., McArdle, P.F., Nutile, T., Porcu, E., Robino, A., Rose, L.M., Schick, U.M., Smith, J.A., Teumer, A., Traglia, M., Vuckovic, D., Yao, J., Zhao, W., Albrecht, E., Amin, N., Corre, T., Hottenga, J.J., Mangino, M., Smith, A.V., Tanaka, T., Abecasis, G.R., Andrulis, I.L., Anton-Culver, H., Antoniou, A.C., Arndt, V., Arnold, A.M., Barbieri, C., Beckmann, M.W., Beeghly-Fadiel, A., Benitez, J., Bernstein, L., Bielinski, S.J., Blomqvist, C., Boerwinkle, E., Bogdanova, N.V., Bojesen, S.E., Bolla, M.K., Borresen-Dale, A.L., Boutin, T.S., Brauch, H., Brenner, H., Bruning, T., Burwinkel, B., Campbell, A., Campbell, H., Chanock, S.J., Chapman, J.R., Chen, Y.D.I., Chenevix-Trench, G., Couch, F.J., Coviello, A.D., Cox, A., Czene, K., Darabi, H., Vivo, I. de, Demerath, E.W., Dennis, J., Devilee, P., Dork, T., Dos-Santos-Silva, I., Dunning, A.M., Eicher, J.D., Fasching, P.A., Faul, J.D., Figueroa, J., Flesch-Janys, D., Gandin, I., Garcia, M.E., Garcia-Closas, M., Giles, G.G., Girotto, G.G., Goldberg, M.S., Gonzalez-Neira, A., Goodarzi, M.O., Grove, M.L., Gudbjartsson, D.F., Guenel, P., Guo, X.Q., Haiman, C.A., Hall, P., Hamann, U., Henderson, B.E., Hocking, L.J., Hofman, A., Homuth, G., Hooning, M.J., Hopper, J.L., Hu, F.B., Huang, J.Y., Humphreys, K., Hunter, D.J., Jakubowska, A., Jones, S.E., Kabisch, M., Karasik, D., Knight, J.A., Kolcic, I., Kooperberg, C., Kosma, V.M., Kriebel, J., Kristensen, V., Lambrechts, D., Langenberg, C., Li, J.M., Li, X., Lindstrom, S., Liu, Y.M., Luan, J.N., Lubinski, J., Magi, R., Mannermaa, A., Manz, J., Margolin, S., Marten, J., Martin, N.G., Masciullo, C., Meindl, A., Michailidou, K., Mihailov, E., Milani, L., Milne, R.L., Muller-Nurasyid, M., Nalls, M., Neale, B.M., Nevanlinna, H., Neven, P., Newman, A.B., Nordestgaard, B.G., Olson, J.E., Padmanabhan, S., Peterlongo, P., Peters, U., Petersmann, A., Peto, J., Pharoah, P.D.P., Pirastu, N.N., Pirie, A., Pistis, G., Polasek, O., Porteous, D., Psaty, B.M., Pylkas, K., Radice, P., Raffel, L.J., Rivadeneira, F., Rudan, I., Rudolph, A., Ruggiero, D., Sala, C.F., Sanna, S., Sawyer, E.J., Schlessinger, D., Schmidt, M.K., Schmidt, F., Schmutzler, R.K., Schoemaker, M.J., Scott, R.A., Seynaeve, C.M., Simard, J., Sorice, R., Southey, M.C., Stockl, D., Strauch, K., Swerdlow, A., Taylor, K.D., Thorsteinsdottir, U., Toland, A.E., Tomlinson, I., Truong, T., Tryggvadottir, L., Turner, S.T., Vozzi, D., Wang, Q., Wellons, M., Willemsen, G., Wilson, J.F., Winqvist, R., Wolffenbuttel, B.B.H.R., Wright, A.F., Yannoukakos, D., Zemunik, T., Zheng, W., Zygmunt, M., Bergmann, S., Boomsma, D.I., Buring, J.E., Ferrucci, L., Montgomery, G.W., Gudnason, V., Spector, T.D., Duijn, C.M. van, Alizadeh, B.Z., Ciullo, M., Crisponi, L., Easton, D.F., Gasparini, P.P., Gieger, C., Harris, T.B., Hayward, C., Kardia, S.L.R., Kraft, P., McKnight, B., Metspalu, A., Morrison, A.C., Reiner, A.P., Ridker, P.M., Rotter, J.I., Toniolo, D., Uitterlinden, A.G., Ulivi, S., Volzke, H., Wareham, N.J., Weir, D.R., Yerges-Armstrong, L.M., Price, A.L., Stefansson, K., Visser, J.A., Ong, K.K., Chang-Claude, J., Murabito, J.M., Perry, J.R.B., Murray, A., EPIC-InterAct Consortium, LifeLines Cohort Study
Published 2015

Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes

by Pulit, S.L., Weng, L.C., McArdle, P.F., Trinquart, L., Choi, S.H., Mitchell, B.D., Rosand, J., Bakker, P.I.W. de, Benjamin, E.J., Ellinor, P.T., Kittner, S.J., Lubitz, S.A., Anderson, C.D., Christophersen, I.E., Rienstra, M., Roselli, C., Yin, X.Y., Geelhoed, B., Barnard, J., Lin, H.H., Arking, D.E., Smith, A.V., Albert, C.M., Chaffin, M., Tucker, N.R., Li, M.L., Klarin, D., Bihlmeyer, N.A., Low, S.K., Weeke, P.E., Muller-Nurasyid, M., Smith, J.G., Brody, J.A., Niemeijer, M.N., Dorr, M., Trompet, S., Huffman, J., Gustafsson, S., Schurmann, C., Kleber, M.E., Lyytikainen, L.P., Seppala, I., Malik, R., Horimoto, A.R.V.R., Perez, M., Sinisalo, J., Aeschbacher, S., Theriault, S., Yao, J., Radmanesh, F., Weiss, S., Teumer, A., Clauss, S., Deo, R., Rader, D.J., Shah, S., Sun, A., Hopewell, J.C., Debette, S., Chauhan, G., Yang, Q., Worrall, B.B., Pare, G., Kamatani, Y., Hagemeijer, Y.P., Verweij, N., Siland, J.E., Kubo, M., Smith, J.D., Wagoner, D.R. van, Bis, J.C., Perz, S., Psaty, B.M., Ridker, P.M., Magnani, J.W., Harris, T.B., Launer, L.J., Shoemaker, M.B., Padmanabhan, S., Haessler, J., Bartz, T.M., Waldenberger, M., Lichtner, P., Arendt, M., Krieger, J.E., Kahonen, M., Risch, L., Mansur, A.J., Peters, A., Smith, B.H., Lind, L., Scott, S.A., Lu, Y.C., Bottinger, E.B., Hernesniemi, J., Lindgren, C.M., Wong, J.A., Huang, J., Eskola, M., Morris, A.P., Ford, I., Reiner, A.P., Delgado, G., Chen, L.Y., Chen, Y.D.I., Sandhu, R.K., Li, M., Boerwinkle, E., Eisele, L., Lannfelt, L., Rost, N., Taylor, K.D., Campbell, A., Magnusson, P.K., Porteous, D., Hocking, L.J., Vlachopoulou, E., Pedersen, N.L., Nikus, K., Orho-Melander, M., Hamsten, A., Heeringa, J., Denny, J.C., Kriebel, J., Darbar, D., Newton-Cheh, C., Shaffer, C., Macfarlane, P.W., Heilmann, S., Almgren, P., Huang, P.L., Sotoodehnia, N., Soliman, E.Z., Uitterlinden, A.G., Hofman, A., Franco, O.H., Volker, U., Jockel, K.H., Sinner, M.F., Lin, H.J., Guo, X.Q., Dichgans, M., Ingelsson, E., Kooperberg, C., Melander, O., Loos, R.J.F., Laurikka, J., Conen, D., Harst, P. van der, Lokki, M.L., Kathiresan, S., Pereira, A., Jukema, J.W., Hayward, C., Rotter, J.I., Marz, W., Lehtimaki, T., Stricker, B.H., Chung, M.K., Felix, S.B., Gudnason, V., Alonso, A., Roden, D.M., Kaab, S., Chasman, D.I., Heckbert, S.R., Tanaka, T., Lunetta, K.L., Smoller, S., Sorkin, J., Wang, X.W., Selim, M., Pikula, A., Wolf, P., Seshadri, S., Bakker, P. de, Chasman, D., Rexrode, K., Chen, I., Rotter, J., Luke, M., Sale, M., Lee, T.H., Chang, K.C., Elkind, M., Goldstein, L., James, M.L., Breteler, M., O'Donnell, C., Leys, D., Carty, C., Kidwell, C., Olesen, J., Sharma, P., Rich, S., Tatlisumak, T., Happola, O., Bijlenga, P., Soriano, C., Giralt, E., Roquer, J., Jimenez-Conde, J., Cotlarcius, I., Hardy, J., Korostynski, M., Boncoraglio, G., Ballabio, E., Parati, E., Mateusz, A., Urbanik, A., Dziedzic, T., Jagiella, J., Gasowski, J., Wnuk, M., Olszanecki, R., Pera, J., Slowik, A., Juchniewicz, K.J., Levi, C., Nyquist, P., Cendes, I., Cabral, N., Franca, P., Goncalves, A., Keller, L., Crisby, M., Kostulas, K., Lemmens, R., Ahmadi, K., Opherk, C., Duering, M., Gonik, M., Staals, J., Burri, P., Sadr-Nabavi, A., Romero, J., Biffi, A., Anderson, C., Falcone, G., Brouwers, B., , R. du, Kourkoulis, C., Battey, T., Lubitz, S., Mueller-Myhsok, B., Meschia, J., Brott, T., Pichler, A., Enzinger, C., Schmidt, H., Schmidt, R., Seiler, S., Blanton, S., Yamada, Y., Bersano, A., Rundek, T., Sacco, R., Chan, Y.F.Y., Gschwendtner, A., Deng, Z., Barr, T., Gwinn, K., Corriveau, R., Singleton, A., Waddy, S., Launer, L., Chen, C., , K.E. le, Lee, W.L., Tan, E.K., Olugbodi, A., Rothwell, P., Schilling, S., Mok, V., Lebedeva, E., Jern, C., Jood, K., Olsson, S., Kim, H., Lee, C., Kilarski, L., Markus, H., Peycke, J., Bevan, S., Sheu, W., Chiou, H.Y., Chern, J., Giraldo, E., Taqi, M., Jain, V., Lam, O., Howard, G., Woo, D., Kittner, S., Mitchell, B., Cole, J., O'Connell, J., Milewicz, D., Illoh, K
Published 2018

Rare and low-frequency coding variants alter human adult height

by Marouli, E., Graff, M., Medina-Gomez, C., , K.S. lo, Wood, A.R., Kjaer, T.R., Fine, R.S., Lu, Y.C., Schurmann, C., Highland, H.M., Rueger, S., Thorleifsson, G., Justice, A.E., Lamparter, D., Stirrups, K.E., Turcot, V., Young, K.L., Winkler, T.W., Esko, T., Karaderi, T., Locke, A.E., Masca, N.G.D., Ng, M.C.Y., Mudgal, P., Rivas, M.A., Vedantam, S., Mahajan, A., Guo, X.Q., Abecasis, G., Aben, K.K., Adair, L.S., Alam, D.S., Albrecht, E., Allin, K.H., Allison, M., Amouyel, P., Appel, E.V., Arveiler, D., Asselbergs, F.W., Auer, P.L., Balkau, B., Banas, B., Bang, L.E., Benn, M., Bergmann, S., Bielak, L.F., Bluher, M., Boeing, H., Boerwinkle, E., Boger, C.A., Bonnycastle, L.L., Bork-Jensen, J., Bots, M.L., Bottinger, E.P., Bowden, D.W., Brandslund, I., Breen, G., Brilliant, M.H., Broer, L., Burt, A.A., Butterworth, A.S., Carey, D.J., Caulfield, M.J., Chambers, J.C., Chasman, D.I., Chen, Y.D.I., Chowdhury, R., Christensen, C., Chu, A.Y., Cocca, M., Collins, F.S., Cook, J.P., Corley, J., Galbany, J.C., Cox, A.J., Cuellar-Partida, G., Danesh, J., Davies, G., Bakker, P.I.W. de, Borst, G.J. de, Denus, S. de, Groot, M.C.H. de, Mutsert, R. de, Deary, I.J., Dedoussis, G., Demerath, E.W., Hollander, A.I. den, Dennis, J.G., Angelantonio, E. di, Drenos, F., , M.M. du, Dunning, A.M., Easton, D.F., Ebeling, T., Edwards, T.L., Ellinor, P.T., Elliott, P., Evangelou, E., Farmaki, A.E., Faul, J.D., Feitosa, M.F., Feng, S., Ferrannini, E., Ferrario, M.M., Ferrieres, J., Florez, J.C., Ford, I., Fornage, M., Franks, P.W., Frikke-Schmidt, R., Galesloot, T.E., Gan, W., Gandin, I., Gasparini, P., Giedraitis, V., Giri, A., Girotto, G., Gordon, S.D., Gordon-Larsen, P., Gorski, M., Grarup, N., Grove, M.L., Gudnason, V., Gustafsson, S., Hansen, T., Harris, K.M., Harris, T.B., Hattersley, A.T., Hayward, C., He, L., Heid, I.M., Heikkila, K., Helgeland, O., Hernesniemi, J., Hewitt, A.W., Hocking, L.J., Hollensted, M., Holmen, O.L., Hovingh, G.K., Howson, J.M.M., Hoyng, C.B., Huang, P.L., Hveem, K., Ikram, M.A., Ingelsson, E., Jackson, A.U., Jansson, J.H., Jarvik, G.P., Jensen, G.B., Jhun, M.A., Jia, Y.C., Jiang, X.J., Johansson, S., Jorgensen, M.E., Jorgensen, T., Jousilahti, P., Jukema, J.W., Kahali, B., Kahn, R.S., Kahonen, M., Kamstrup, P.R., Kanoni, S., Kaprio, J., Karaleftheri, M., Kardia, S.L.R., Karpe, F., Kee, F., Keeman, R., Kiemeney, L.A., Kitajima, H., Kluivers, K.B., Kocher, T., Komulainen, P., Kontto, J., Kooner, J.S., Kooperberg, C., Kovacs, P., Kriebel, J., Kuivaniemi, H., Kury, S., Kuusisto, J., Bianca, M. la, Laakso, M., Lakka, T.A., Lange, E.M., Lange, L.A., Langefeld, C.D., Langenberg, C., Larson, E.B., Lee, I.T., Lehtimaki, T., Lewis, C.E., Li, H.X., Li, J., Li-Gao, R., Lin, H.H., Lin, L.A., Lin, X., Lind, L., Lindstrom, J., Linneberg, A., Liu, Y.H., Liu, Y.M., Lophatananon, A., Luan, J., Lubitz, S.A., Lyytikainen, L.P., Mackey, D.A., Madden, P.A.F., Manning, A.K., Mannisto, S., Marenne, G., Marten, J., Martin, N.G., Mazul, A.L., Meidtner, K., Metspalu, A., Mitchell, P., Mohlke, K.L., Mook-Kanamori, D.O., Morgan, A., Morris, A.D., Morris, A.P., Muller-Nurasyid, M., Munroe, P.B., Nalls, M.A., Nauck, M., Nelson, C.P., Neville, M., Nielsen, S.F., Nikus, K., Njolstad, P.R., Nordestgaard, B.G., Ntalla, I., O'Connel, J.R., Oksa, H., Loohuis, L.M.O., Ophoff, R.A., Owen, K.R., Packard, C.J., Padmanabhan, S., Palmer, C.N.A., Pasterkamp, G., Patel, A.P., Pattie, A., Pedersen, O., Peissig, P.L., Peloso, G.M., Pennell, C.E., Perola, M., Perry, J.A., Perry, J.R.B., Person, T.N., Pirie, A., Polasek, O., Posthuma, D., Raitakari, O.T., Rasheed, A., Rauramaa, R., Reilly, D.F., Reiner, A.P., Renstrom, F., Ridker, P.M., Rioux, J.D., Robertson, N., Robino, A., Rolandsson, O., Rudan, I., Ruth, K.S., Saleheen, D., Salomaa, V., Samani, N.J., Sandow, K., Sapkota, Y., Sattar, N., Schmidt, M.K., Schreiner, P.J., Schulze, M.B., Scott, R.A., Segura-Lepe, M.P., Shah, S., Sim, X.L., Sivapalaratnam, S., Small
Published 2017

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease

by Webb, TR, Erdmann, J, Stirrups, KE, Stitziel, NO, Masca, NGD, Jansen, H, Kanoni, S, Nelson, CP, Ferrario, PG, König, IR, Eicher, JD, Johnson, AD, Hamby, SE, Betsholtz, C, Ruusalepp, A, Franzén, O, Schadt, EE, Björkegren, JLM, Weeke, PE, Auer, PL, Schick, UM, Lu, Y, Zhang, H, Dube, M-P, Goel, A, Farrall, M, Peloso, GM, Won, H-H, Do, R, van Iperen, E, Kruppa, J, Mahajan, A, Scott, RA, Willenborg, C, Braund, PS, van Capelleveen, JC, Doney, ASF, Donnelly, LA, Asselta, R, Merlini, PA, Duga, S, Marziliano, N, Denny, JC, Shaffer, C, El-Mokhtari, NE, Franke, A, Heilmann, S, Hengstenberg, C, Hoffmann, P, Holmen, OL, Hveem, K, Jansson, J-H, Jöckel, K-H, Kessler, T, Kriebel, J, Laugwitz, KL, Marouli, E, Martinelli, N, McCarthy, MI, Van Zuydam, NR, Meisinger, C, Esko, T, Mihailov, E, Escher, SA, Alver, M, Moebus, S, Morris, AD, Virtamo, J, Nikpay, M, Olivieri, O, Provost, S, AlQarawi, A, Robertson, NR, Akinsansya, KO, Reilly, DF, Vogt, TF, Yin, W, Asselbergs, FW, Kooperberg, C, Jackson, RD, Stahl, E, Müller-Nurasyid, M, Strauch, K, Varga, TV, Waldenberger, M, Wellcome Trust Case Control Consortium, Zeng, L, Chowdhury, R, Salomaa, V, Ford, I, Jukema, JW, Amouyel, P, Kontto, J, MORGAM Investigators, Nordestgaard, BG, Ferrières, J, Saleheen, D, Sattar, N, Surendran, P, Wagner, A, Young, R, Howson, JMM, Butterworth, AS, Danesh, J, Ardissino, D, Bottinger, EP, Erbel, R, Franks, PW, Girelli, D, Hall, AS, Hovingh, GK, Kastrati, A, Lieb, W, Meitinger, T, Kraus, WE, Shah, SH, McPherson, R, Orho-Melander, M, Melander, O, Metspalu, A, Palmer, CNA, Peters, A, Rader, DJ, Reilly, MP, Loos, RJF, Reiner, AP, Roden, DM, Tardif, J-C, Thompson, JR, Wareham, NJ, Watkins, H, Willer, CJ, Samani, NJ, Schunkert, H, Deloukas, P, Kathiresan, S, Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators
Published 2017

Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

by Mahajan, A., Spracklen, C.N., Zhang, W.H., Ng, M.C.Y., Petty, L.E., Kitajima, H., Yu, G.Z., Rueger, S., Speidel, L., Kim, Y.J., Horikoshi, M., Mercader, J.M., Taliun, D., Moon, S., Kwak, S.H., Robertson, N.R., Rayner, N.W., Loh, M., Kim, B.J., Chiou, J., Miguel-Escalada, I., Parolo, P.D., Lin, K., Bragg, F., Preuss, M.H., Takeuchi, F., Nano, J., Guo, X.Q., Lamri, A., Nakatochi, M., Scott, R.A., Lee, J.J., Huerta-Chagoya, A., Graff, M., Chai, J.F., Parra, E.J., Yao, J., Bielak, L.F., Tabara, Y., Hai, Y., Steinthorsdottir, V., Cook, J.P., Kals, M., Grarup, N., Schmidt, E.M., Pan, I., Sofer, T., Wuttke, M., Sarnowski, C., Gieger, C., Nousome, D., Trompet, S., Long, J.R., Sun, M., Tong, L., Chen, W.M., Ahmad, M., Noordam, R., Lim, V.J.Y., Tam, C.H.T., Joo, Y.Y., Chen, C.H., Raffield, L.M., Lecoeur, C., Prins, B.P., Nicolas, A., Yanek, L.R., Chen, G.J., Jensen, R.A., Tajuddin, S., Kabagambe, E.K., An, P., Xiang, A.H., Choi, H.S., Cade, B.E., Tan, J.Y., Flanagan, J., Abaitua, F., Adair, L.S., Adeyemo, A., Aguilar-Salinas, C.A., Akiyama, M., Anand, S.S., Bertoni, A., Bian, Z., Bork-Jensen, J., Brandslund, I., Brody, J.A., Brummett, C.M., Buchanan, T.A., Canouil, M., Chan, J.C.N., Chang, L.C., Chee, M.L., Chen, J., Chen, S.H., Chen, Y.T., Chen, Z.M., Chuang, L.M., Cushman, M., , S.K. das, Silva, H.J. de, Dedoussis, G., Dimitrov, L., Doumatey, A.P., , S.F. du, Duan, Q., Eckardt, K.U., Emery, L.S., Evans, D.S., Evans, M.K., Fischer, K., Floyd, J.S., Ford, I., Fornage, M., Franco, O.H., Frayling, T.M., Freedman, B.I., Fuchsberger, C., Genter, P., Gerstein, H.C., Giedraitis, V., Gonzalez-Villalpando, C., Gonzalez-Villalpando, M.E., Goodarzi, M.O., Gordon-Larsen, P., Gorkin, D., Gross, M., Guo, Y., Hackinger, S., Han, S., Hattersley, A.T., Herder, C., Howard, A.G., Hsueh, W., Huang, M.N., Huang, W., Hung, Y.J., Hwang, M.Y., Hwu, C.M., Ichihara, S., Ikram, M.A., Ingelsson, M., Islam, M.T., Isono, M., Jang, H.M., Jasmine, F., Jiang, G.Z., Jonas, J.B., Jorgensen, M.E., Jorgensen, T., Kamatani, Y., Kandeel, F.R., Kasturiratne, A., Katsuya, T., Kaur, V., Kawaguchi, T., Keaton, J.M., Kho, A.N., Khor, C.C., Kibriya, M.G., Kim, D.H., Kohara, K., Kriebel, J., Kronenberg, F., Kuusisto, J., Lall, K., Lange, L.A., Lee, M.S., Lee, N.R., Leong, A., Li, L.M., Li, Y., Li-Gao, R.F., Ligthart, S., Lindgren, C.M., Linneberg, A., Liu, C.T., Liu, J.J., Locke, A.E., Louie, T., Luan, J.A., Luk, A.O., Luo, X., Lv, J., Lyssenko, V., Mamakou, V., Mani, K.R., Meitinger, T., Metspalu, A., Morris, A.D., Nadkarni, G.N., Nadler, J.L., Nalls, M.A., Nayak, U., Nongmaithem, S.S., Ntalla, I., Okada, Y., Orozco, L., Patel, S.R., Pereira, M.A., Peters, A., Pirie, F.J., Porneala, B., Prasad, G., Preissl, S., Rasmussen-Torvik, L.J., Reiner, A.P., Roden, M., Rohde, R., Roll, K., Sabanayagam, C., Sander, M., Sandow, K., Sattar, N., Schonherr, S., Schurmann, C., Shahriar, M., Shi, J.X., Shin, D.M., Shriner, D., Smith, J.A., So, W.Y., Stancakova, A., Stilp, A.M., Strauch, K., Suzuki, K., Takahashi, A., Taylor, K.D., Thorand, B., Thorleifsson, G., Thorsteinsdottir, U., Tomlinson, B., Torres, J.M., Tsai, F.J., Tuomilehto, J., Tusie-Luna, T., Udler, M.S., Valladares-Salgado, A., Dam, R.M. van, Klinken, J.B. van, Varma, R., Vujkovic, M., Wacher-Rodarte, N., Wheeler, E., Whitsel, E.A., Wickremasinghe, A.R., Dijk, K.W. van, Witte, D.R., Yajnik, C.S., Yamamoto, K., Yamauchi, T., Yengo, L., Yoon, K., Yu, C.Q., Yuan, J.M., Yusuf, S., Zhang, L., Zheng, W., Raffel, L.J., Igase, M., Ipp, E., Redline, S., Cho, Y.S., Lind, L., Province, M.A., Hanis, C.L., Peyser, P.A., Ingelsson, E., Zonderman, A.B., Psaty, B.M., Wang, Y.X., Rotimi, C.N., Becker, D.M., Matsuda, F., Liu, Y.M., Zeggini, E., Yokota, M., Rich, S.S., Kooperberg, C., Pankow, J.S., Engert, J.C., Chen, Y.D.I., Froguel, P., Wilson, J.G., Sheu, W.H.H., Kardia, S.L.R., Wu, J.Y., Hayes, M.G., Ma, R.C.W., Wong, T.Y., Groop, L., Mook-Kanamori, D.O., Chandak, G.R., Collins, F.S., Bharadwaj, D.
Published 2022

A Low-Frequency Inactivating Akt2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

by Manning, A, Highland, HM, Gasser, J, Sim, X, Tukiainen, T, Fontanillas, P, Grarup, N, Rivas, MA, Mahajan, A, Locke, AE, Cingolani, P, Pers, TH, Viñuela, A, Brown, AA, Wu, Y, Flannick, J, Fuchsberger, C, Gamazon, ER, Gaulton, KJ, Im, HK, Teslovich, TM, Blackwell, TW, Bork-Jensen, J, Burtt, NP, Chen, Y, Green, T, Hartl, C, Kang, HM, Kumar, A, Ladenvall, C, Ma, C, Moutsianas, L, Pearson, RD, Perry, JRB, Rayner, NW, Robertson, NR, Scott, LJ, van de Bunt, M, Eriksson, JG, Jula, A, Koskinen, S, Lehtimäki, T, Palotie, A, Raitakari, OT, Jacobs, SB, Wessel, J, Chu, AY, Scott, RA, Goodarzi, MO, Blancher, C, Buck, G, Buck, D, Chines, PS, Gabriel, S, Gjesing, AP, Groves, CJ, Hollensted, M, Huyghe, JR, Jackson, AU, Jun, G, Justesen, JM, Mangino, M, Murphy, J, Neville, M, Onofrio, R, Small, KS, Stringham, HM, Trakalo, J, Banks, E, Carey, J, Carneiro, MO, DePristo, M, Farjoun, Y, Fennell, T, Goldstein, JI, Grant, G, Hrabé de Angelis, M, Maguire, J, Neale, BM, Poplin, R, Purcell, S, Schwarzmayr, T, Shakir, K, Smith, JD, Strom, TM, Wieland, T, Lindstrom, J, Brandslund, I, Christensen, C, Surdulescu, GL, Lakka, TA, Doney, ASF, Nilsson, P, Wareham, NJ, Langenberg, C, Varga, TV, Franks, PW, Rolandsson, O, Rosengren, AH, Farook, VS, Thameem, F, Puppala, S, Kumar, S, Lehman, DM, Jenkinson, CP, Curran, JE, Hale, DE, Fowler, SP, Arya, R, DeFronzo, RA, Abboud, HE, Syvänen, A-C, Hicks, PJ, Palmer, ND, Ng, MCY, Bowden, DW, Freedman, BI, Esko, T, Mägi, R, Milani, L, Mihailov, E, Metspalu, A, Narisu, N, Kinnunen, L, Bonnycastle, LL, Swift, A, Pasko, D, Wood, AR, Fadista, J, Pollin, TI, Barzilai, N, Atzmon, G, Glaser, B, Thorand, B, Strauch, K, Peters, A, Roden, M, Müller-Nurasyid, M, Liang, L, Kriebel, J, Illig, T, Grallert, H, Gieger, C, Meisinger, C, Lannfelt, L, Musani, SK, Griswold, M, Taylor, HA, Wilson, G, Correa, A, Oksa, H, Scott, WR, Afzal, U, Tan, S-T, Loh, M, Chambers, JC, Sehmi, J, Kooner, JS, Lehne, B, Cho, YS, Lee, J-Y, Han, B-G, Käräjämäki, A, Qi, Q, Qi, L, Huang, J, Hu, FB, Melander, O, Orho-Melander, M, Below, JE, Aguilar, D, Wong, TY, Liu, J, Khor, C-C, Chia, KS, Lim, WY, Cheng, C-Y, Chan, E, Tai, ES, Aung, T, Linneberg, A, Isomaa, B, Meitinger, T, Tuomi, T, Hakaste, L, Kravic, J, Jørgensen, ME, Lauritzen, T, Deloukas, P, Stirrups, KE, Owen, KR, Farmer, AJ, Frayling, TM, O'Rahilly, SP, Walker, M, Levy, JC, Hodgkiss, D, Hattersley, AT, Kuulasmaa, T, Stančáková, A, Barroso, I, Bharadwaj, D, Chan, J, Chandak, GR, Daly, MJ, Donnelly, PJ, Ebrahim, SB, Elliott, P, Fingerlin, T, Froguel, P, Hu, C, Jia, W, Ma, RCW, McVean, G, Park, T, Prabhakaran, D, Sandhu, M, Scott, J, Sladek, R, Tandon, N, Teo, YY, Zeggini, E, Watanabe, RM, Koistinen, HA, Kesaniemi, YA, Uusitupa, M, Spector, TD, Salomaa, V, Rauramaa, R, Palmer, CNA, Prokopenko, I, Morris, AD, Bergman, RN, Collins, FS, Lind, L, Ingelsson, E, Tuomilehto, J, Karpe, F, Groop, L, Jørgensen, T, Hansen, T, Pedersen, O, Kuusisto, J, Abecasis, G, Bell, GI, Blangero, J, Cox, NJ, Duggirala, R, Seielstad, M, Wilson, JG, Dupuis, J, Ripatti, S, Hanis, CL, Florez, JC, Mohlke, KL, Meigs, JB, Laakso, M, Morris, AP, Boehnke, M, Altshuler, D, McCarthy, MI, Gloyn, AL, Lindgren, CM
Published 2017