Exome and Whole Genome Sequencing in Aging and Longevity

by Akker, E.B. van den, Deelen, J., Slagboom, P.E., Beekman, M., Atzmon, G.
Published 2015

Activation-Induced Autophagy Is Preserved in CD4(+)T-Cells in Familial Longevity

by Raz, Y., Guerrero-Ros, I., Maier, A., Slagboom, P.E., Atzmon, G., Barzilai, N., Macian, F.
Published 2017

Distinguishing Between Longevity and Buffered-Deleterious Genotypes for Exceptional Human Longevity: The Case of the MTP Gene

by Huffman, D.M., Deelen, J., Ye, K., Bergman, A., Slagboom, E.P., Barzilai, N., Atzmon, G.
Published 2012

A Human Variant of Glucose-Regulated Protein 94 That Inefficiently Supports IGF Production

by Marzec, M., Hawkes, C.P., Eletto, D., Boyle, S., Rosenfeld, R., Hwa, V., Wit, J.M., Duyvenvoorde, H.A. van, Oostdijk, W., Losekoot, M., Pedersen, O., Yeap, B.B., Flicker, L., Barzilai, N., Atzmon, G., Grimberg, A., Argon, Y.
Published 2016

The complex genetics of gait speed: genome-wide meta-analysis approach (vol 9, pg 209, 2017)

by Ben-Avraham, D., Karasik, D., Verghese, J., Lunetta, K.L., Smith, J.A., Eicher, J.D., Vered, R., Deelen, J., Arnold, A.M., Buchman, A.S., Tanaka, T., Faul, J.D., Nethander, M., Fornage, M., Adams, H.H., Matteini, A.M., Callisaya, M.L., Smith, A.V., Yu, L., Jager, P.L. de, Evans, D.A., Gudnason, V., Hofman, A., Pattie, A., Corley, J., Launer, L.J., Knopman, D.S., Parimi, N., Turner, S.T., Bandinelli, S., Beekman, M., Gutman, D., Sharvit, L., Mooijaart, S.P., Liewald, D.C., Houwing-Duistermaat, J.J., Ohlsson, C., Moed, M., Verlinden, V.J., Mellstrom, D., Geest, J.N. van der, Karlsson, M., Hernandez, D., McWhirter, R., Liu, Y.M., Thomson, R., Tranah, G.J., Uitterlinden, A.G., Weir, D.R., Zhao, W., Starr, J.M., Johnson, A.D., Ikram, M.A., Bennett, D.A., Cummings, S.R., Deary, I.J., Harris, T.B., Kardia, S.L.R., Mosley, T.H., Srikanth, V.K., Windham, B.G., Newman, A.B., Walston, J.D., Davies, G., Evans, D.S., Slagboom, E.P., Ferrucci, L., Kiel, D.P., Murabito, J.M., Atzmon, G.
Published 2017

The complex genetics of gait speed: genome-wide meta-analysis approach

by Ben-Avraham, D., Karasik, D., Verghese, J., Lunetta, K.L., Smith, J.A., Eicher, J.D., Vered, R., Deelen, J., Arnold, A.M., Buchman, A.S., Tanaka, T., Faul, J.D., Nethander, M., Fornage, M., Adams, H.H., Matteini, A.M., Callisaya, M.L., Smith, A.V., Yu, L., Jager, P.L. de, Evans, D.A., Gudnason, V., Hofman, A., Pattie, A., Corley, J., Launer, L.J., Knopman, D.S., Parimi, N., Turner, S.T., Bandinelli, S., Beekman, M., Gutman, D., Sharvit, L., Mooijaart, S.P., Liewald, D.C., Houwing-Duistermaat, J.J., Ohlsson, C., Moed, M., Verlinden, V.J., Mellstrom, D., Geest, J.N. van der, Karlsson, M., Hernandez, D., McWhirter, R., Liu, Y.M., Thomson, R., Tranah, G.J., Uitterlinden, A.G., Weir, D.R., Zhao, W., Starr, J.M., Johnson, A.D., Ikram, M.A., Bennett, D.A., Cummings, S.R., Deary, I.J., Harris, T.B., Kardia, S.L.R., Mosley, T.H., Srikanth, V.K., Windham, B.G., Newman, A.B., Walston, J.D., Davies, G., Evans, D.S., Slagboom, E.P., Ferrucci, L., Kiel, D.P., Murabito, J.M., Atzmon, G.
Published 2017

Body mass index is negatively associated with telomere length: a collaborative cross-sectional meta-analysis of 87 observational studies

by Gielen, M., Hageman, G.J., Antoniou, E.E., Nordfjall, K., Mangino, M., Balasubramanyam, M., Meyer, T. de, Hendricks, A.E., Giltay, E.J., Hunt, S.C., Nettleton, J.A., Salpea, K.D., Diaz, V.A., Farzaneh-Far, R., Atzmon, G., Harris, S.E., Hou, L.F., Gilley, D., Hovatta, I., Kark, J.D., Nassar, H., Kurz, D.J., Mather, K.A., Willeit, P., Zheng, Y.L., Pavanello, S., Demerath, E.W., Rode, L., Bunout, D., Steptoe, A., Boardman, L., Marti, A., Needham, B., Zheng, W., Ramsey-Goldman, R., Pellatt, A.J., Kaprio, J., Hofmann, J.N., Gieger, C., Paolisso, G., Hjelmborg, J.B.H., Mirabello, L., Seeman, T., Wong, J., Harst, P. van der, Broer, L., Kronenberg, F., Kollerits, B., Strandberg, T., Eisenberg, D.T.A., Duggan, C., Verhoeven, J.E., Schaakxs, R., Zannolli, R., Reis, R.M.R. dos, Charchar, F.J., Tomaszewski, M., Mons, U., Demuth, I., Molli, A.E.I., Cheng, G., Krasnienkov, D., D'Antono, B., Kasielski, M., McDonnell, B.J., Ebstein, R.P., Sundquist, K., Pare, G., Chong, M., Zeegers, M.P., TELOMAAS Group
Published 2018

A meta-analysis of genome-wide association studies identifies multiple longevity genes

by Deelen, J., Evans, D.S., Arking, D.E., Tesi, N., Nygaard, M., Liu, X.M., Wojczynski, M.K., Biggs, M.L., Spek, A. van der, Atzmon, G., Ware, E.B., Sarnowski, C., Smith, A.V., Seppala, I., Cordell, H.J., Dose, J., Amin, N., Arnold, A.M., Ayers, K.L., Barzilai, N., Becker, E.J., Beekman, M., Blanche, H., Christensen, K., Christiansen, L., Collerton, J.C., Cubaynes, S., Cummings, S.R., Davies, K., Debrabant, B., Deleuze, J.F., Duncan, R., Faul, J.D., Franceschi, C., Galan, P., Gudnaso, V., Harris, T.B., Huisman, M., Hurme, M.A., Jagger, C., Jansen, I., Jylha, M., Kahonen, M., Karasik, D., Kardia, S.L.R., Kingston, A., Kirkwood, T.B.L., Launer, L.J., Lehtimaki, T., Lieb, W.G., Lyytikainen, L.P., Martin-Ruiz, C., Min, J.X., Nebe, A., Newman, A.B., Nie, C., Nohr, E.A., Orwoll, E.S., Perls, T.T., Province, M.A., Psat, B.M., Raitakari, O.T., Reinders, M.J.T., Robine, J.M., Rotter, J.I., Sebastiani, P., Smith, J., Sorensen, T.I.A., Taylor, K.D., Uitterlinden, A.G., Flier, W. van der, Lee, S.J. van der, Duijn, C.M. van, Heemst, D. van, Vaupel, J.W., Weir, D., Ye, K., Zeng, Y., Zheng, W.L., Holstege, H., Kiel, D.P., Lunetta, K.L., Slagboom, P.E., Murabito, J.M.
Published 2019

Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico

by Williams Amy, A.L., Jacobs Suzanne, S.B.R., Moreno-Macías, H., Huerta-Chagoya, A., Churchhouse, C., Márquez-Luna, C., Gómez-Vázquez, M.J., Burtt Noël, N.P., Aguilar-Salinas, C.A., González-Villalpando, C., Florez, J.C., Orozco, L., Tusié-Luna, T., Altshuler, D., Ripke, S., Manning, A.K., García-Ortíz, H., Neale, B., Reich, D., Stram, D.O., Fernández-López, J.C., Romero-Hidalgo, S., Patterson, N., Haiman, C.A., Aguilar-Delfín, I., Martínez-Hernández, A., Centeno-Cruz, F., Mendoza-Caamal, E., Revilla-Monsalve, C., Islas-Andrade, S., Córdova, E., Rodríguez-Arellano, E., Soberón, X., Florez Jose, J.C., González-Villalpando María Elena, M.A., Henderson, B.E., Monroe, K., Wilkens, L., Kolonel, L.N., Le Marchand, L., Riba, L., Ordóñez-Sánchez María Luisa, M.A., Rodríguez-Guillén, R., Cruz-Bautista, I., Rodríguez-Torres, M., Muñoz-Hernández, L.L., Sáenz, T., Gómez, D., Alvirde, U., Onofrio, R.C., Brodeur, W.M., Gage, D., Murphy, J., Franklin, J., Mahan, S., Ardlie, K., Crenshaw, A.T., Winckler, W., Prüfer, K., Shunkov, M.V., Sawyer, S., Stenzel, U., Kelso, J., Lek, M., Sankararaman, S., MacArthur, D.G., Derevianko, A.P., Pääbo, S., Jacobs, S.B.R., Gopal, S., Grammatikos, J.A., Smith, I.C., Bullock, K.H., Deik, A.A., Souza, A.L., Pierce, K.A., Clish, C.B., Fennell, T., Farjoun, Y., Gabriel, S., Gross, M.D., Pereira, M.A., Seielstad, M., Koh, W.-P., Tai, E.-S., Flannick, J., Fontanillas, P., Morris, A., Teslovich, T.M., Atzmon, G., Blangero, J., Bowden, D.W., Chambers, J., Cho, Y.S., Duggirala, R., Glaser, B., Hanis, C., Kooner, J., Laakso, M., Lee, J.-Y., Teo, Y.Y., Wilson, J.G., Puppala, S., Farook, V.S., Thameem, F., Abboud, H.E., DeFronzo, R.A., Jenkinson, C.P., Lehman, D.M., Curran, J.E., Cortes, M.L., González-Villalpando Clicerio, C., Orozco Lorena, L.
Published 2014

A new strategy for enhancing imputation quality of rare variants from next-generation sequencing data via combining SNP and exome chip data

by Kim Y.J., Lee J., Kim B.-J., Park T., Abecasis G., Almeida M., Altshuler D., Asimit J.L., Atzmon G., Barber M., Barzilai N., Beer N.L., Bell G.I., Below J., Blackwell T., Blangero J., Boehnke M., Bowden D.W., Burtt N., Chambers J., Chen H., Chen P., Chines P.S., Choi S., Churchhouse C., Cingolani P., Cornes B.K., Cox N., Day-Williams A.G., Duggirala R., Dupuis J., Dyer T., Feng S., Fernandez-Tajes J., Ferreira T., Fingerlin T.E., Flannick J., Florez J., Fontanillas P., Frayling T.M., Fuchsberger C., Gamazon E.R., Gaulton K., Ghosh S., Glaser B., Gloyn A., Grossman R.L., Grundstad J., Hanis C., Heath A., Highland H., Horikoshi M., Huh I.-S., Huyghe J.R., Ikram K., Jablonski K.A., Jun G., Kato N., Kim J., Kim Y.J., Kim B.-J., Lee J., King C.R., Kooner J., Kwon M.-S., Im H.K., Laakso M., Lam K.K.-Y., Lee J., Lee S., Lee S., Lehman D.M., Li H., Lindgren C.M., Liu X., Livne O.E., Locke A.E., Mahajan A., Maller J.B., Manning A.K., Maxwell T.J., Mazoure A., McCarthy M.I., Meigs J.B., Min B., Mohlke K.L., Morris A.P., Musani S., Nagai Y., Ng M.C.Y., Nicolae D., Oh S., Palmer N., Park T., Pollin T.I., Prokopenko I., Reich D., Rivas M.A., Scott L.J., Seielstad M., Cho Y.S., Sim X., Sladek R., Smith P., Tachmazidou I., Tai E.S., Teo Y.Y., Teslovich T.M., Torres J., Trubetskoy V., Willems S.M., Williams A.L., Wilson J.G., Wiltshire S., Won S., Wood A.R., Xu W., Yoon J., Zawistowski M., Zeggini E., Zhang W., Zöllner S.
Published 2018

Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes

by Wang, Q., Pierce-Hoffman, E., Cummings, B.B., Alföldi, J., Francioli, L.C., Gauthier, L.D., Hill, A.J., O’Donnell-Luria, A.H., Armean, I.M., Banks, E., Bergelson, L., Cibulskis, K., Collins, R.L., Connolly, K.M., Covarrubias, M., Daly, M.J., Donnelly, S., Farjoun, Y., Ferriera, S., Gabriel, S., Gentry, J., Gupta, N., Jeandet, T., Kaplan, D., Laricchia, K.M., Llanwarne, C., Minikel, E.V., Munshi, R., Neale, B.M., Novod, S., Petrillo, N., Poterba, T., Roazen, D., Ruano-Rubio, V., Saltzman, A., Samocha, K.E., Schleicher, M., Seed, C., Solomonson, M., Soto, J., Tiao, G., Tibbetts, K., Tolonen, C., Vittal, C., Wade, G., Wang, A., Ware, J.S., Watts, N.A., Weisburd, B., Whiffin, N., Aguilar Salinas, C.A., Ahmad, T., Albert, C.M., Ardissino, D., Atzmon, G., Barnard, J., Beaugerie, L., Benjamin, E.J., Boehnke, M., Bonnycastle, L.L., Bottinger, E.P., Bowden, D.W., Bown, M.J., Chambers, J.C., Chan, J.C., Chasman, D., Cho, J., Chung, M.K., Cohen, B., Correa, A., Dabelea, D., Darbar, D., Duggirala, R., Dupuis, J., Ellinor, P.T., Elosua, R., Erdmann, J., Esko, T., Färkkilä, M., Florez, J., Franke, A., Getz, G., Glaser, B., Glatt, S.J., Goldstein, D., Gonzalez, C., Groop, L., Haiman, C., Hanis, C., Harms, M., Hiltunen, M., Holi, M.M., Hultman, C.M., Kallela, M., Kaprio, J., Kathiresan, S., Kim, B.-J., Kim, Y.J., Kirov, G., Kooner, J., Koskinen, S., Krumholz, H.M., Kugathasan, S., Kwak, S.H., Laakso, M., Lehtimäki, T., Loos, R.J.F., Lubitz, S.A., Ma, R.C.W., Marrugat, J., Mattila, K.M., McCarroll, S., McCarthy, M.I., McGovern, D., McPherson, R., Meigs, J.B., Melander, O., Metspalu, A., Nilsson, P.M., O’Donovan, M.C., Ongur, D., Orozco, L., Owen, M.J., Palmer, C.N.A., Palotie, A., Park, K.S., Pato, C., Pulver, A.E., Rahman, N., Remes, A.M., Rioux, J.D., Ripatti, S., Roden, D.M., Saleheen, D., Salomaa, V., Samani, N.J., Scharf, J., Schunkert, H., Shoemaker, M.B., Sklar, P., Soininen, H., Sokol, H., Spector, T., Sullivan, P.F., Suvisaari, J., Tai, E.S., Teo, Y.Y., Tiinamaija, T., Tsuang, M., Turner, D., Tusie-Luna, T., Vartiainen, E., Watkins, H., Weersma, R.K., Wessman, M., Wilson, J.G., Xavier, R.J., Karczewski, K.J., MacArthur, D.G., Genome Aggregation Database Production Team., Genome Aggregation Database Consortium.
Published 2021

Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals

by Whiffin, N., Karczewski, K.J., Zhang, X., Chothani, S., Smith, M.J., Evans, D.G., Roberts, A.M., Quaife, N.M., Schafer, S., Rackham, O., Alföldi, J., Hultman, C.M., Wang, A., Wang, Q., Watts, N.A., Weisburd, B., Aguilar Salinas, C.A., Ahmad, T., Albert, C.M., Ardissino, D., Atzmon, G., Francioli, L.C., Barnard, J., Kallela, M., Beaugerie, L., Benjamin, E.J., Boehnke, M., Bonnycastle, L.L., Bottinger, E.P., Bowden, D.W., Bown, M.J., Chambers, J.C., McCarroll, S., Chan, J.C., Chasman, D., Kaprio, J., Cho, J., Chung, M.K., Cohen, B., Correa, A., Dabelea, D., Daly, M.J., Darbar, D., McCarthy, M.I., Duggirala, R., Dupuis, J., Ellinor, P.T., Kathiresan, S., Elosua, R., Erdmann, J., Esko, T., Färkkilä, M., Florez, J., Programs in Metabolism and Medical and Population Genetics, Broad Institute., McGovern, D., Department of Medicine, Harvard Medical School, Boston, MA 02115, United States., Franke, A., Getz, G., Glaser, B., Kim, B.-J., Glatt, S.J., Goldstein, D., Gonzalez, C., Groop, L., Haiman, C., McPherson, R., Hanis, C., Harms, M., Hiltunen, M., Kim, Y.J., Kirov, G., Kooner, J., Koskinen, S., O’Donnell-Luria, A.H., Krumholz, H.M., Kugathasan, S., Meigs, J.B., Kwak, S.H., Laakso, M., Lehtimäki, T., Loos, R.J.F., Lubitz, S.A., Ma, R.C.W., Marrugat, J., Mattila, K.M., Melander, O., Metspalu, A., Neale, B.M., Nilsson, P.M., Llanwarne, C., O’Donovan, M.C., Armean, I.M., Ongur, D., Orozco, L., Owen, M.J., Palmer, C.N.A., Palotie, A., Park, K.S., Pato, C., Pulver, A.E., Minikel, E.V., Rahman, N., Remes, A.M., Banks, E., Rioux, J.D., Ripatti, S., Roden, D.M., Saleheen, D., Salomaa, V., Samani, N.J., Scharf, J., Munshi, R., Schunkert, H., Shoemaker, M.B., Sklar, P., Bergelson, L., Soininen, H., Sokol, H., Spector, T., Sullivan, P.F., Suvisaari, J., Tai, E.S., Neale, B.M., Teo, Y.Y., Tiinamaija, T., Tsuang, M., Turner, D., Cibulskis, K., Tusie-Luna, T., Vartiainen, E., Watkins, H., Weersma, R.K., Wessman, M., Novod, S., Wilson, J.G., Xavier, R.J., Cook, S.A., Collins, R.L., Connolly, K.M., Covarrubias, M., Cummings, B., Daly, M.J., Donnelly, S., Farjoun, Y., Petrillo, N., Ferriera, S., Gabriel, S., Gauthier, L.D., Gentry, J., Gupta, N., Jeandet, T., Kaplan, D., Laricchia, K.M., Poterba, T., Roazen, D., Ruano-Rubio, V., Saltzman, A., Holi, M.M., Samocha, K.E., Schleicher, M., Seed, C., Solomonson, M., Soto, J., Tiao, G., Tibbetts, K., Tolonen, C., Vittal, C., Wade, G.
Published 2021

Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility

by Sazonovs, A., Stevens, C.R., Venkataraman, G.R., Yuan, K., Avila, B., Abreu, M.T., Ahmad, T., Allez, M., Ananthakrishnan, A.N., Atzmon, G., Baras, A., Barrett, J.C., Barzilai, N., Beaugerie, L., Beecham, A., Bernstein, C.N., Bitton, A., Bokemeyer, B., Chan, A., Chung, D., Cleynen, I., Cosnes, J., Cutler, D.J., Daly, A., Damas, O.M., Datta, L.W., Dawany, N., Devoto, M., Dodge, S., Ellinghaus, E., Fachal, L., Farkkila, M., Faubion, W., Ferreira, M., Franchimont, D., Gabriel, S.B., Ge, T., Georges, M., Gettler, K., Giri, M., Glaser, B., Goerg, S., Goyette, P., Graham, D., Hamalainen, E., Haritunians, T., Heap, G.A., Hiltunen, M., Hoeppner, M., Horowitz, J.E., Irving, P., Iyer, V., Jalas, C., Kelsen, J., Khalili, H., Kirschner, B.S., Kontula, K., Koskela, J.T., Kugathasan, S., Kupcinskas, J., Lamb, C.A., Laudes, M., Levesque, C., Levine, A.P., Lewis, J.D., Liefferinckx, C., Loescher, B.S., Louis, E., Mansfield, J., May, S., McCauley, J.L., Mengesha, E., Mni, M., Moayyedi, P., Moran, C.J., Newberry, R.D., O'Charoen, S., Okou, D.T., Oldenburg, B., Ostrer, H., Palotie, A., Paquette, J., Pekow, J., Peter, I., Pierik, M.J., Ponsioen, C.Y., Pontikos, N., Prescott, N., Pulver, A.E., Rahmouni, S., Rice, D.L., Saavalainen, P., Sands, B., Sartor, R.B., Schiff, E.R., Schreiber, S., Schumm, L.P., Segal, A.W., Seksik, P., Shawky, R., Sheikh, S.Z., Silverberg, M.S., Simmons, A., Skeiceviciene, J., Sokol, H., Solomonson, M., Somineni, H., Sun, D., Targan, S., Turner, D., Uhlig, H.H., Meulen, A.E. van der, Vermeire, S., Verstockt, S., Voskuil, M.D., Winter, H.S., Young, J., Duerr, R.H., Franke, A., Brant, S.R., Cho, J., Weersma, R.K., Parkes, M., Xavier, R.J., Rivas, M.A., Rioux, J.D., McGovern, D.P.B., Huang, H.L., Anderson, C.A., Daly, M.J., Belgium IBD Consortium, Cedars-Sinai IBD, Int IBD Genetics Consortium, NIDDK IBD Genetics Consortium, NIHR IBD BioResource, Regeneron Genetics Ctr, SHARE Consortium, SPARC IBD Network, UK IBD Genetics Consortium
Published 2022

Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus

by Mahajan A., SIM XUELING, Ng H.J., Manning A., Rivas M.A., Highland H.M., Locke A.E., Grarup N., Im H.K., Cingolani P., Flannick J., Fontanillas P., Fuchsberger C., Gaulton K.J., Teslovich T.M., Rayner N.W., Robertson N.R., Beer N.L., Rundle J.K., Bork-Jensen J., Ladenvall C., Blancher C., Buck D., Buck G., Burtt N.P., Gabriel S., Gjesing A.P., Groves C.J., Hollensted M., Huyghe J.R., Jackson A.U., Jun G., Justesen J.M., Mangino M., Murphy J., Neville M., Onofrio R., Small K.S., Stringham H.M., Syvänen A.-C., Trakalo J., Abecasis G., Bell G.I., Blangero J., Cox N.J., Duggirala R., Hanis C.L., Seielstad M., Wilson J.G., Christensen C., Brandslund I., Rauramaa R., Surdulescu G.L., Doney A.S.F., Lannfelt L., Linneberg A., Isomaa B., Tuomi T., Jørgensen M.E., Jørgensen T., Kuusisto J., Uusitupa M., Salomaa V., Spector T.D., Morris A.D., Palmer C.N.A., Collins F.S., Mohlke K.L., Bergman R.N., Ingelsson E., Lind L., Tuomilehto J., Hansen T., Watanabe R.M., Prokopenko I., Dupuis J., Karpe F., Groop L., Laakso M., Pedersen O., Florez J.C., Morris A.P., Altshuler D., Meigs J.B., Boehnke M., McCarthy M.I., Lindgren C.M., Gloyn A.L., Abboud H.E., Afzal U., Aguilar D., Arya R., Atzmon G., Aung T., Banks E., Barroso I., Barzilai N., Below J.E., Bharadwaj D., Blackwell T.W., Bonnycastle L.L., Bowden D., Carey J., Carneiro M.O., Chambers J.C., Chan E., Chan J., Chandak G.R., Chen P., Chen Y., Chen H., Cheng C.-Y., Chia K.S., Cho Y.S., Correa A., Curran J.E., Daly M.J., Day-Williams A.G., DeFronzo R.A., DePristo M., Donnelly P.J., Ebrahim S.B., Elliott P., Esko T., Fadista J., Farjoun Y., Farmer A.J., Farook V.S., Fennell T., Ferreira T., Fingerlin T., Forsén T., Fowler S.P., Franks P.W., Frayling T.M., Freedman B.I., Froguel P., Gamazon E.R., Gieger C., Glaser B., Go M.J., Goldstein J.I., Grallert H., Grant G., Green T., Griswold M., Hale D.E., Han B.-G., Hartl C., Hattersley A.T., Hicks P.J., Hodgkiss D., Horikoshi M., Hrabé de Angelis M., Hu C., Hu F.B., Huh I., Kamran Ikram M., Illig T., Jablonski K.A., Jenkinson C.P., Jia W., Kang H.M., Khor C.-C., Kim Y., Kim Y.J., Kim B.-J., Kinnunen L., Kooner J.S., Kravic J., Kriebel J., Kumar A., Kumar S., Kuulasmaa T., Kwon M.-S., Langenberg C., Lauritzen T., Lee S., Lee J., Lee J., Lee J.-Y., Lehman D.M., Lehne B., Levy J.C., Li J., Liang L., Lim W.Y., Lin K.-H., Liu J., Loh M., Ma R.C.W., Ma C., Mägi R., Maguire J., Maxwell T.J., McVean G., Meisinger C., Meitinger T., Melander O., Metspalu A., Mihailov E., Milani L., Moutsianas L., Müller-Nurasyid M., K. Musani S., Nagai Y., Narisu N., Neale B.M., Ng M.C.Y., Nilsson P., O'Rahilly S.P., Orho-Melander M., Owen K.R., Palmer N.D., Park T., Pasko D., Pearson R.D., Perry J.R.B., Peters A., Pollin T.I., Poplin R., Prabhakaran D., Puppala S., Purcell S., Qi L., Qi Q., Roden M., Rolandsson O., Rosengren A.H., Sandhu M., Schwarzmayr T., Scott L.J., Scott R.A., Scott J., Scott W.R., Sehmi J., Shakir K., Sladek R., Smith J.D., Stancáková A., Strauch K., Strom T.M., Swift A., Tai E.S., Tajes J.F., Tan S.-T., Tandon N., Taylor H.A., Jr., Teo Y.Y., Thameem F., Thorand B., van de Bunt M., Varga T.V., Walker M., Wareham N.J., Welch R.P., Wieland T., Wilson G., Sr., Wong T.Y., Wood A.R., Yoon J., Zeggini E., Zhang W.
Published 2018

Genome-wide analysis identifies 12 loci influencing human reproductive behavior.

by Barban, N, Jansen, R, de Vlaming, R, Vaez, A, Mandemakers, JJ, Tropf, FC, Shen, X, Wilson, JF, Chasman, DI, Nolte, IM, Tragante, V, van der Laan, SW, Perry, JRB, Kong, A, BIOS Consortium, Ahluwalia, TS, Albrecht, E, Yerges-Armstrong, L, Atzmon, G, Auro, K, Ayers, K, Bakshi, A, Ben-Avraham, D, Berger, K, Bergman, A, Bertram, L, Bielak, LF, Bjornsdottir, G, Bonder, MJ, Broer, L, Bui, M, Barbieri, C, Cavadino, A, Chavarro, JE, Turman, C, Concas, MP, Cordell, HJ, Davies, G, Eibich, P, Eriksson, N, Esko, T, Eriksson, J, Falahi, F, Felix, JF, Fontana, MA, Franke, L, Gandin, I, Gaskins, AJ, Gieger, C, Gunderson, EP, Guo, X, Hayward, C, He, C, Hofer, E, Huang, H, Joshi, PK, Kanoni, S, Karlsson, R, Kiechl, S, Kifley, A, Kluttig, A, Kraft, P, Lagou, V, Lecoeur, C, Lahti, J, Li-Gao, R, Lind, PA, Liu, T, Makalic, E, Mamasoula, C, Matteson, L, Mbarek, H, McArdle, PF, McMahon, G, Meddens, SFW, Mihailov, E, Miller, M, Missmer, SA, Monnereau, C, van der Most, PJ, Myhre, R, Nalls, MA, Nutile, T, Kalafati, IP, Porcu, E, Prokopenko, I, Rajan, KB, Rich-Edwards, J, Rietveld, CA, Robino, A, Rose, LM, Rueedi, R, Ryan, KA, Saba, Y, Schmidt, D, Smith, JA, Stolk, L, Streeten, E, Tönjes, A, Thorleifsson, G, Ulivi, S, Wedenoja, J, Wellmann, J, Willeit, P, Yao, J, Yengo, L, Zhao, JH, Zhao, W, Zhernakova, DV, Amin, N, Andrews, H, Balkau, B, Barzilai, N, Bergmann, S, Biino, G, Bisgaard, H, Bønnelykke, K, Boomsma, DI, Buring, JE, Campbell, H, Cappellani, S, Ciullo, M, Cox, SR, Cucca, F, Toniolo, D, Davey-Smith, G, Deary, IJ, Dedoussis, G, Deloukas, P, van Duijn, CM, de Geus, EJC, Eriksson, JG, Evans, DA, Faul, JD, Sala, CF, Froguel, P, Gasparini, P, Girotto, G, Grabe, H-J, Greiser, KH, Groenen, PJF, de Haan, HG, Haerting, J, Harris, TB, Heath, AC, Heikkilä, K, Hofman, A, Homuth, G, Holliday, EG, Hopper, J, Hyppönen, E, Jacobsson, B, Jaddoe, VWV, Johannesson, M, Jugessur, A, Kähönen, M, Kajantie, E, Kardia, SLR, Keavney, B, Kolcic, I, Koponen, P, Kovacs, P, Kronenberg, F, Kutalik, Z, La Bianca, M, Lachance, G, Iacono, WG, Lai, S, Lehtimäki, T, Liewald, DC, LifeLines Cohort Study, Lindgren, CM, Liu, Y, Luben, R, Lucht, M, Luoto, R, Magnus, P, Magnusson, PKE, Martin, NG, McGue, M, McQuillan, R, Medland, SE, Meisinger, C, Mellström, D, Metspalu, A, Traglia, M, Milani, L, Mitchell, P, Montgomery, GW, Mook-Kanamori, D, de Mutsert, R, Nohr, EA, Ohlsson, C, Olsen, J, Ong, KK, Paternoster, L, Pattie, A, Penninx, BWJH, Perola, M, Peyser, PA, Pirastu, M, Polasek, O, Power, C, Kaprio, J, Raffel, LJ, Räikkönen, K, Raitakari, O, Ridker, PM, Ring, SM, Roll, K, Rudan, I, Ruggiero, D, Rujescu, D, Salomaa, V, Schlessinger, D, Schmidt, H, Schmidt, R, Schupf, N, Smit, J, Sorice, R, Spector, TD, Starr, JM, Stöckl, D, Strauch, K, Stumvoll, M, Swertz, MA, Thorsteinsdottir, U, Thurik, AR, Timpson, NJ, Tung, JY, Uitterlinden, AG, Vaccargiu, S, Viikari, J, Vitart, V, Völzke, H, Vollenweider, P, Vuckovic, D, Waage, J, Wagner, GG, Wang, JJ, Wareham, NJ, Weir, DR, Willemsen, G, Willeit, J, Wright, AF, Zondervan, KT, Stefansson, K, Krueger, RF, Lee, JJ, Benjamin, DJ, Cesarini, D, Koellinger, PD, den Hoed, M, Snieder, H, Mills, MC
Published 2016

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

by Barban, N., Jansen, R., Vlaming, R. de, Vaez, A., Mandemakers, J.J., Tropf, F.C., Shen, X., Wilson, J.F., Chasman, D.I., Nolte, I.M., Tragante, V., Laan, S.W. van der, Perry, J.R.B., Kong, A., Ahluwalia, T.S., Albrecht, E., Yerges-Armstrong, L., Atzmon, G., Auro, K., Ayers, K., Bakshi, A., Ben-Avraham, D., Berger, K., Bergman, A., Bertram, L., Bielak, L.F., Bjornsdottir, G., Bonder, M.J., Broer, L., Bui, M., Barbieri, C., Cavadino, A., Chavarro, J.E., Turman, C., Concas, M.P., Cordell, H.J., Davies, G., Eibich, P., Eriksson, N., Esko, T., Eriksson, J., Falahi, F., Felix, J.F., Fontana, M.A., Franke, L., Gandin, I., Gaskins, A.J., Gieger, C., Gunderson, E.P., Guo, X.Q., Hayward, C., He, C.Y., Hofer, E., Huang, H.Y., Joshi, P.K., Kanoni, S., Karlsson, R., Kiechl, S., Kifley, A., Kluttig, A., Kraft, P., Lagou, V., Lecoeur, C., Lahti, J., Li-Gao, R.F., Lind, P.A., Liu, T., Makalic, E., Mamasoula, C., Matteson, L., Mbarek, H., McArdle, P.F., McMahon, G., Meddens, S.F.W., Mihailov, E., Miller, M., Missmer, S.A., Monnereau, C., Most, P.J. van der, Myhre, R., Nalls, M.A., Nutile, T., Kalafati, I.P., Porcu, E., Prokopenko, I., Rajan, K.B., Rich-Edwards, J., Rietveld, C.A., Robino, A., Rose, L.M., Rueedi, R., Ryan, K.A., Saba, Y., Schmidt, D., Smith, J.A., Stolk, L., Streeten, E., Tonjes, A., Thorleifsson, G., Ulivi, S., Wedenoja, J., Wellmann, J., Willeit, P., Yao, J., Yengo, L., Zhao, J.H., Zhao, W., Zhernakova, D.V., Amin, N., Andrews, H., Balkau, B., Barzilai, N., Bergmann, S., Biino, G., Bisgaard, H., Bonnelykke, K., Boomsma, D.I., Buring, J.E., Campbell, H., Cappellani, S., Ciullo, M., Cox, S.R., Cucca, F., Toniolo, D., Davey-Smith, G., Deary, I.J., Dedoussis, G., Deloukas, P., Duijn, C.M. van, Geus, E.J.C. de, Eriksson, J.G., Evans, D.A., Faul, J.D., Sala, C.F., Froguel, P., Gasparini, P., Girotto, G., Grabe, H.J., Greiser, K.H., Groenen, P.J.F., Haan, H.G. de, Haerting, J., Harris, T.B., Heath, A.C., Heikkila, K., Hofman, A., Homuth, G., Holliday, E.G., Hopper, J., Hypponen, E., Jacobsson, B., Jaddoe', V.W.V., Johannesson, M., Kahonen, M., Kajantie, E., Kardia, S.L.R., Keavney, B., Kolcic, I., Koponen, P., Kovacs, P., Kronenberg, F., Kutalik, Z., Bianca, M. la, Lachance, G., Iacono, W.G., Lai, S., Lehtimaki, T., Liewald, D.C., Lindgren, C.M., Liu, Y.M., Luben, R., Lucht, M., Luoto, R., Magnus, P., Magnusson, P.K.E., Martin, N.G., McGue, M., McQuillan, R., Medland, S.E., Meisinger, C., Mellstrom, D., Metspalu, A., Traglia, M., Milani, L., Mitchell, P., Montgomery, G.W., Mook-Kanamori, D., Mutsert, R. de, Nohr, E.A., Ohlsson, C., Olsen, P., Ong, K.K., Paternoster, L., Pattie, A., Penninx, B.W.J.H., Perola, M., Peyser, P.A., Pirastu, M., Polasek, O., Power, C., Kaprio, J., Raffel, L.J., Raikkonen, K., Raitakari, O., Ridker, P.M., Ring, S.M., Roll, K., Rudan, I., Ruggiero, D., Rujescu, D., Salomaa, V., Schlessinger, D., Schmidt, H., Schmidt, R., Schupf, N., Smit, J., Sorice, R., Spector, T.D., Starr, J.M., Stockl, D., Strauch, K., Stumvoll, M., Swertz, M.A., Thorsteinsdottir, U., Thurik, A.R., Timpson, N.J., Tung, J.Y., Uitterlinden, A.G., Vaccargiu, S., Viikari, J., Vitart, V., Volzke, H., Vollenweider, P., Vuckovic, D., Waage, J., Wagner, G.G., Wang, J.J., Wareham, N.J., Weir, D.R., Willemsen, G., Willeit, J., Wright, A.F., Zondervan, K.T., Stefansson, K., Krueger, R.F., Lee, J.J., Benjamin, D.J., Cesarini, D., Koellinger, P.D., Hoed, M. den, Snieder, H., Mills, M.C., Bios Consortium, LifeLines Cohort Study
Published 2016

A Low-Frequency Inactivating Akt2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

by Manning, A, Highland, HM, Gasser, J, Sim, X, Tukiainen, T, Fontanillas, P, Grarup, N, Rivas, MA, Mahajan, A, Locke, AE, Cingolani, P, Pers, TH, Viñuela, A, Brown, AA, Wu, Y, Flannick, J, Fuchsberger, C, Gamazon, ER, Gaulton, KJ, Im, HK, Teslovich, TM, Blackwell, TW, Bork-Jensen, J, Burtt, NP, Chen, Y, Green, T, Hartl, C, Kang, HM, Kumar, A, Ladenvall, C, Ma, C, Moutsianas, L, Pearson, RD, Perry, JRB, Rayner, NW, Robertson, NR, Scott, LJ, van de Bunt, M, Eriksson, JG, Jula, A, Koskinen, S, Lehtimäki, T, Palotie, A, Raitakari, OT, Jacobs, SB, Wessel, J, Chu, AY, Scott, RA, Goodarzi, MO, Blancher, C, Buck, G, Buck, D, Chines, PS, Gabriel, S, Gjesing, AP, Groves, CJ, Hollensted, M, Huyghe, JR, Jackson, AU, Jun, G, Justesen, JM, Mangino, M, Murphy, J, Neville, M, Onofrio, R, Small, KS, Stringham, HM, Trakalo, J, Banks, E, Carey, J, Carneiro, MO, DePristo, M, Farjoun, Y, Fennell, T, Goldstein, JI, Grant, G, Hrabé de Angelis, M, Maguire, J, Neale, BM, Poplin, R, Purcell, S, Schwarzmayr, T, Shakir, K, Smith, JD, Strom, TM, Wieland, T, Lindstrom, J, Brandslund, I, Christensen, C, Surdulescu, GL, Lakka, TA, Doney, ASF, Nilsson, P, Wareham, NJ, Langenberg, C, Varga, TV, Franks, PW, Rolandsson, O, Rosengren, AH, Farook, VS, Thameem, F, Puppala, S, Kumar, S, Lehman, DM, Jenkinson, CP, Curran, JE, Hale, DE, Fowler, SP, Arya, R, DeFronzo, RA, Abboud, HE, Syvänen, A-C, Hicks, PJ, Palmer, ND, Ng, MCY, Bowden, DW, Freedman, BI, Esko, T, Mägi, R, Milani, L, Mihailov, E, Metspalu, A, Narisu, N, Kinnunen, L, Bonnycastle, LL, Swift, A, Pasko, D, Wood, AR, Fadista, J, Pollin, TI, Barzilai, N, Atzmon, G, Glaser, B, Thorand, B, Strauch, K, Peters, A, Roden, M, Müller-Nurasyid, M, Liang, L, Kriebel, J, Illig, T, Grallert, H, Gieger, C, Meisinger, C, Lannfelt, L, Musani, SK, Griswold, M, Taylor, HA, Wilson, G, Correa, A, Oksa, H, Scott, WR, Afzal, U, Tan, S-T, Loh, M, Chambers, JC, Sehmi, J, Kooner, JS, Lehne, B, Cho, YS, Lee, J-Y, Han, B-G, Käräjämäki, A, Qi, Q, Qi, L, Huang, J, Hu, FB, Melander, O, Orho-Melander, M, Below, JE, Aguilar, D, Wong, TY, Liu, J, Khor, C-C, Chia, KS, Lim, WY, Cheng, C-Y, Chan, E, Tai, ES, Aung, T, Linneberg, A, Isomaa, B, Meitinger, T, Tuomi, T, Hakaste, L, Kravic, J, Jørgensen, ME, Lauritzen, T, Deloukas, P, Stirrups, KE, Owen, KR, Farmer, AJ, Frayling, TM, O'Rahilly, SP, Walker, M, Levy, JC, Hodgkiss, D, Hattersley, AT, Kuulasmaa, T, Stančáková, A, Barroso, I, Bharadwaj, D, Chan, J, Chandak, GR, Daly, MJ, Donnelly, PJ, Ebrahim, SB, Elliott, P, Fingerlin, T, Froguel, P, Hu, C, Jia, W, Ma, RCW, McVean, G, Park, T, Prabhakaran, D, Sandhu, M, Scott, J, Sladek, R, Tandon, N, Teo, YY, Zeggini, E, Watanabe, RM, Koistinen, HA, Kesaniemi, YA, Uusitupa, M, Spector, TD, Salomaa, V, Rauramaa, R, Palmer, CNA, Prokopenko, I, Morris, AD, Bergman, RN, Collins, FS, Lind, L, Ingelsson, E, Tuomilehto, J, Karpe, F, Groop, L, Jørgensen, T, Hansen, T, Pedersen, O, Kuusisto, J, Abecasis, G, Bell, GI, Blangero, J, Cox, NJ, Duggirala, R, Seielstad, M, Wilson, JG, Dupuis, J, Ripatti, S, Hanis, CL, Florez, JC, Mohlke, KL, Meigs, JB, Laakso, M, Morris, AP, Boehnke, M, Altshuler, D, McCarthy, MI, Gloyn, AL, Lindgren, CM
Published 2017