Metabolomics analytics workflow for epidemiological research: Perspectives from the consortium of metabolomics studies (COMETS)

by Playdon, M.C., Joshi, A.D., Tabung, F.K., Cheng, S., Henglin, M., Kim, A., Lin, T., van Roekel, E.H., Huang, J., Krumsiek, J., Wang, Y., Mathé, E., Temprosa, M., Moore, S., Chawes, B., Eliassen, A.H., Gsur, A., Gunter, M.J., Harada, S., Langenberg, C., Oresic, M., Perng, W., Seow, W.J., Zeleznik, O.A.
Published 2021

Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomis...

by Strawbridge, R.J., Silveira, A., Hoed, M. den, Gustafsson, S., Luan, J.A., Rybin, D., Dupuis, J., Li-Gao, R.F., Kavousi, M., Dehghan, A., Haljas, K., Lahti, J., Gadin, J.R., Backlund, A., Faire, U. de, Gertow, K., Giral, P., Goel, A., Humphries, S.E., Kurl, S., Langenberg, C., Lannfelt, L.L., Lind, L., Lindgren, C.C.M., Mannarino, E., Mook-Kanamori, D.O., Morris, A.P., Mutsert, R. de, Rauramaa, R., Saliba-Gustafsson, P., Sennblad, B., Smit, A.J., Syvanen, A.C., Tremoli, E., Veglia, F., Zethelius, B., Bjorck, H.M., Eriksson, J.G., Hofman, A., Franco, O.H., Watkins, H., Jukema, J.W., Florez, J.C., Wareham, N.J., Meigs, J.B., Ingelsson, E., Baldassarre, D., Hamsten, A., IMPROVE Study Grp
Published 2017

Integrated Analyses of Microbiome and Longitudinal Metabolome Data Reveal Microbial-Host Interactions on Sulfur Metabolism in Parkinson's Disease

by Hertel, J., Harms, A.C., Heinken, A., Baldini, F., Thinnes, C.C., Glaab, E., Vasco, D.A., Pietzner, M., Stewart, I.D., Wareham, N.J., Langenberg, C., Trenkwalder, C., Kruger, R., Hankemeier, T., Fleming, R.M.T., Mollenhauer, B., Thiele, I.
Published 2019

Dairy product intake and risk of type 2 diabetes in EPIC-InterAct: A Mendelian randomization study

by Vissers, LET, Sluijs, I, van der Schouw, VT, Forouhi, N, Imamura, F, Burgess, Stephen, Barricarte, A, Boeing, H, Bonet, C, Chirlaque, M, Fagherazzi, G, Franks, PW, Freisling, H, Gunter, MJ, Quirós, JR, Ibsen, DB, Kaaks, R, Key, T, Khaw, K, Kühn, T, Mokoroa, O, Nilsson, PM, Overvad, K, Pala, V, Palli, D, Panico, S, Sacerdote, C, Spijkermann, MW, Tjonneland, A, Tumino, R, Rodríguez-Barranco, M, Rolandsson, O, Riboli, E, Sharp, SJ, Langenberg, C, Wareham, N
Published 2019

Rare and low-frequency coding variants alter human adult height

by Stirrups, KE, Butterworth, AS, Chowdhury, R, Danesh, J, Di Angelantonio, E, Howson, JMM, Surendran, P, Young, R, Dennis, JG, Easton, DF, Thompson, DJ, Dunning, AM, Pirie, A, Tyrer, JP, Langenberg, C, Luan, J, Scott, RA, Wareham, NJ, Willems, SM, Zhao, JH, Sivapalaratnam, S
Published 2017

Mendelian Randomization Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes

by Yaghootkar, H., Lamina, C., Scott, R.A., Dastani, Z., Hivert, M.F., Warren, L.L., Stancakova, A., Buxbaum, S.G., Lyytikaeinen, L.P., Henneman, P., Wu, Y., Cheung, C.Y.Y., Pankow, J.S., Jackson, A.U., Gustafsson, S., Zhao, J.H., Ballantyne, C.M., Xie, W.J., Bergman, R.N., Boehnke, M., Bouazzaoui, F. el, Collins, F.S., Dunn, S.H., Dupuis, J., Forouhi, N.G., Gillson, C., Hattersley, A.T., Hong, J.Y., Kaehoenen, M., Kuusisto, J., Kedenko, L., Kronenberg, F., Doria, A., Assimes, T.L., Ferrannini, E., Hansen, T., Hao, K., Haering, H., Knowles, J.W., Lindgren, C.M., Nolan, J.J., Paananen, J., Pedersen, O., Quertermous, T., Smith, U., Lehtimaeki, T., Liu, C.T., Loos, R.J.F., McCarthy, M.I., Morris, A.D., Vasan, R.S., Spector, T.D., Teslovich, T.M., Tuomilehto, J., Dijk, K.W. van, Viikari, J.S., Zhu, N., Langenberg, C., Ingelsson, E., Semple, R.K., Sinaiko, A.R., Palmer, C.N.A., Walker, M., Lam, K.S.L., Paulweber, B., Mohlke, K.L., Duijn, C. van, Raitakari, O.T., Bidulescu, A., Wareham, N.J., Laakso, M., Waterworth, D.M., Lawlor, D.A., Meigs, J.B., Richards, J.B., Frayling, T.M., GENESIS Consortium, RISC Consortium
Published 2013

MC3R links nutritional state to childhood growth and the timing of puberty.

by Lam, BYH, Williamson, A, Finer, S, Day, FR, Tadross, JA, Gonçalves Soares, A, Wade, K, Sweeney, P, Bedenbaugh, MN, Porter, DT, Melvin, A, Ellacott, KLJ, Lippert, RN, Buller, S, Rosmaninho-Salgado, J, Dowsett, GKC, Ridley, KE, Xu, Z, Cimino, I, Rimmington, D, Rainbow, K, Duckett, K, Holmqvist, S, Khan, A, Dai, X, Bochukova, EG, Genes & Health Research Team, Trembath, RC, Martin, HC, Coll, AP, Rowitch, DH, Wareham, NJ, van Heel, DA, Timpson, N, Simerly, RB, Ong, KK, Cone, RD, Langenberg, C, Perry, JRB, Yeo, GS, O'Rahilly, S
Published 2021

Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium

by Merino, J., Dashti, H.S., Li, S.X., Sarnowski, C., Justice, A.E., Graff, M., Papoutsakis, C., Smith, C.E., Dedoussis, G.V., Lemaitre, R.N., Wojczynski, M.K., Mannisto, S., Ngwa, J.S., Kho, M., Ahluwalia, T.S., Pervjakova, N., Houston, D.K., Bouchard, C., Huang, T., Orho-Melander, M., Frazier-Wood, A.C., Mook-Kanamori, D.O., Perusse, L., Pennell, C.E., Vries, P.S. de, Voortman, T., Li, O., Kanoni, S., Rose, L.M., Lehtimaki, T., Zhao, J.H., Feitosa, M.F., Luan, J.A., McKeown, N.M., Smith, J.A., Hansen, T., Eklund, N., Nalls, M.A., Rankinen, T., Huang, J.Y., Hernandez, D.G., Schulz, C.A., Manichaikul, A., Li-Gao, R.F., Vohl, M.C., Wang, C.A., Rooij, F.J.A. van, Shin, J., Kalafati, I.P., Day, F., Ridker, P.M., Kahonen, M., Siscovick, D.S., Langenberg, C., Zhao, W., Astrup, A., Knekt, P., Garcia, M., Rao, D.C., Qi, Q.B., Ferrucci, L., Ericson, U., Blangero, J., Hofman, A., Pausova, Z., Mikkila, V., Wareham, N.J., Kardia, S.L.R., Pedersen, O., Jula, A., Curran, J.E., Zillikens, M.C., Viikari, J.S., Forouhi, N.G., Ordovas, J.M., Lieske, J.C., Rissanen, H., Uitterlinden, A.G., Raitakari, O.T., Kiefte-de Jong, J.C., Dupuis, J., Rotter, J.I., North, K.E., Scott, R.A., Province, M.A., Perola, M., Cupples, L.A., Turner, S.T., Sorensen, T.I.A., Salomaa, V., Liu, Y.M., Sung, Y.J., Qi, L., Bandinelli, S., Rich, S.S., Mutsert, R. de, Tremblay, A., Oddy, W.H., Franco, O.H., Paus, T., Florez, J.C., Deloukas, P., Lyytikainen, L.P., Chasman, D.I., Chu, A.Y., Tanaka, T.
Published 2019

Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes

by Strawbridge, R.J., Dupuis, J., Prokopenko, I., Barker, A., Ahlqvist, E., Rybin, D., Petrie, J.R., Travers, M.E., Bouatia-Naji, N., Dimas, A.S., Nica, A., Wheeler, E., Chen, H., Voight, B.F., Taneera, J., Kanoni, S., Peden, J.F., Turrini, F., Gustafsson, S., Zabena, C., Almgren, P., Barker, D.J.P., Barnes, D., Dennison, E.M., Eriksson, J.G., Eriksson, P., Eury, E., Folkersen, L., Fox, C.S., Frayling, T.M., Goel, A., Gu, H.F., Horikoshi, M., Isomaa, B., Jackson, A.U., Jameson, K.A., Kajantie, E., Kerr-Conte, J., Kuulasmaa, T., Kuusisto, J., Loos, R.J.F., Luan, J.A., Makrilakis, K., Manning, A.K., Martinez-Larrad, M.T., Narisu, N., Mannila, M.N., Ohrvik, J., Osmond, C., Pascoe, L., Payne, F., Sayer, A.A., Sennblad, B., Silveira, A., Stancakova, A., Stirrups, K., Swift, A.J., Syvanen, A.C., Tuomi, T., Hooft, F.M. van 't, Walker, M., Weedon, M.N., Xie, W.J., Zethelius, B., Ongen, H., Malarstig, A., Hopewell, J.C., Saleheen, D., Chambers, J., Parish, S., Danesh, J., Kooner, J., Ostenson, C.G., Lind, L., Cooper, C.C., Serrano-Rios, M., Ferrannini, E., Forsen, T.J., Clarke, R., Franzosi, M.G., Seedorf, U., Watkins, H., Froguel, P., Johnson, P., Deloukas, P., Collins, F.S., Laakso, M., Dermitzakis, E.T., Boehnke, M., McCarthy, M.I., Wareham, N.J., Groop, L., Pattou, F., Gloyn, A.L., Dedoussis, G.V., Lyssenko, V., Meigs, J.B., Barroso, I., Watanabe, R.M., Ingelsson, E., Langenberg, C., Hamsten, A., Florez, J.C., DIAGRAM Consortium, GIANT Consortium, MuTHER Consortium, CARDIoGRAM Consortium, C4D Consortium
Published 2011

Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium.

by Merino, J., Dashti, H.S., Li, S.X., Sarnowski, C., Justice, A.E., Graff, M., Papoutsakis, C., Smith, C.E., Dedoussis, G.V., Lemaitre, R.N., Wojczynski, M.K., Männistö, S., Ngwa, J.S., Kho, M., Ahluwalia, T.S., Pervjakova, N., Houston, D.K., Bouchard, C., Huang, T., Orho-Melander, M., Frazier-Wood, A.C., Mook-Kanamori, D.O., Pérusse, L., Pennell, C.E., Vries, P.S. de, Voortman, T., Li, O., Kanoni, S., Rose, L.M., Lehtimäki, T., Zhao, J.H., Feitosa, M.F., Luan, J., McKeown, N.M., Smith, J.A., Hansen, T., Eklund, N., Nalls, M.A., Rankinen, T., Huang, J., Hernandez, D.G., Schulz, C.A., Manichaikul, A., Li-Gao, R., Vohl, M.C., Wang, C.A., Rooij, F.J.A. van, Shin, J., Kalafati, I.P., Day, F., Ridker, P.M., Kähönen, M., Siscovick, D.S., Langenberg, C., Zhao, W., Astrup, A., Knekt, P., Garcia, M., Rao, D.C., Qi, Q., Ferrucci, L., Ericson, U., Blangero, J., Hofman, A., Pausova, Z., Mikkilä, V., Wareham, N.J., Kardia, S.L.R., Pedersen, O., Jula, A., Curran, J.E., Zillikens, M.C., Viikari, J.S., Forouhi, N.G., Ordovás, J.M., Lieske, J.C., Rissanen, H., Uitterlinden, A.G., Raitakari, O.T., Kiefte-de Jong, J.C., Dupuis, J., Rotter, J.I., North, K.E., Scott, R.A., Province, M.A., Perola, M., Cupples, L.A., Turner, S.T., Sørensen, T.I.A., Salomaa, V., Liu, Y., Sung, Y.J., Qi, L., Bandinelli, S., Rich, S.S., Mutsert, R. de, Tremblay, A., Oddy, W.H., Franco, O.H., Paus, T., Florez, J.C., Deloukas, P., Lyytikäinen, L.P., Chasman, D.I., Chu, A.Y., Tanaka, T.
Published 2018

Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects

by Medina-Gomez, C., Kemp, J.P., Trajanoska, K., Luan, J.A., Chesi, A., Ahluwalia, T.S., Mook-Kanamori, D.O., Ham, A., Hartwig, F.P., Evans, D.S., Joro, R., Nedeljkovic, I., Zheng, H.F., Zhu, K., Atalay, M., Liu, C.T., Nethander, M., Broer, L., Porleifsson, G., Mullin, B.H., Handelman, S.K., Nalls, M.A., Jessen, L.E., Heppe, D.H.M., Richards, J.B., Wang, C., Chawes, B., Schraut, K.E., Amin, N., Wareham, N., Karasik, D., Velde, N. van der, Ikram, M.A., Zemel, B.S., Zhou, Y.H., Carlsson, C.J., Liu, Y.M., McGuigan, F.E., Boer, C.G., Bonnelykke, K., Ralston, S.H., Robbins, J.A., Walsh, J.P., Zillikens, M.C., Langenberg, C., Li-Gao, R., Williams, F.M.K., Harris, T.B., Akesson, K., Jackson, R.D., Sigurdsson, G., Heijer, M. den, Eerden, B.C.J. van der, Peppel, J. van de, Spector, T.D., Pennell, C., Horta, B.L., Felix, J.F., Zhao, J.H., Wilson, S.G., Mutsert, R. de, Bisgaard, H., Styrkarsdottir, U., Jaddoe, V.W., Orwoll, E., Lakka, T.A., Scott, R., Grant, S.F.A., Lorentzon, M., Duijn, C.M. van, Wilson, J.F., Stefansson, K., Psaty, B.M., Kiel, D.P., Ohlsson, C., Ntzani, E., Wijnen, A.J. van, Forgetta, V., Ghanbari, M., Logan, J.G., Williams, G.R., Bassett, J.H.D., Croucher, P.I., Evangelou, E., Uitterlinden, A.G., Ackert-Bicknell, C.L., Tobias, J.H., Evans, D.M., Rivadeneira, F.
Published 2018

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

by Giri, A., Hellwege, J.N., Keaton, J.M., Park, J., Qiu, C.X., Warren, H.R., Torstenson, E.S., Kovesdy, C.P., Sun, Y.V., Wilson, O.D., Robinson-Cohen, C., Roumie, C.L., Chung, C.P., Birdwell, K.A., Damrauer, S.M., DuVall, S.L., Klarin, D., Cho, K., Wang, Y., Evangelou, E., Cabrera, C.P., Wain, L.V., Shrestha, R., Mautz, B.S., Akwo, E.A., Sargurupremraj, M., Debette, S., Boehnke, M., Scott, L.J., Luan, J.A., Zhao, J.H., Willems, S.M., Theriault, S., Shah, N., Oldmeadow, C., Almgren, P., Li-Gao, R., Verweij, N., Boutin, T.S., Mangino, M., Ntalla, I., Feofanova, E., Surendran, P., Cook, J.P., Karthikeyan, S., Lahrouchi, N., Liu, C.Y., Sepulveda, N., Richardson, T.G., Kraja, A., Amouyel, P., Farrall, M., Poulter, N.R., Laakso, M., Zeggini, E., Sever, P., Scott, R.A., Langenberg, C., Wareham, N.J., Conen, D., Palmer, C.N.A., Attia, J., Chasman, D.I., Ridker, P.M., Melander, O., Mook-Kanamori, D.O., Harst, P. van der, Cucca, F., Schlessinger, D., Hayward, C., Spector, T.D., Jarvelin, M.R., Hennig, B.J., Timpson, N.J., Wei, W.Q., Smith, J.C., Xu, Y.M., Matheny, M.E., Siew, E.E., Lindgren, C., Herzig, K.H., Dedoussis, G., Denny, J.C., Psaty, B.M., Howson, J.M.M., Munroe, P.B., Newton-Cheh, C., Caulfield, M.J., Elliott, P., Gaziano, J.M., Concato, J., Wilson, P.W.F., Tsao, P.S., Edwards, D.R.V., Susztak, K., O'Donnell, C.J., Hung, A.M., Edwards, T.L., Understanding Soc Sci Grp, Int Consortium Blood Pressure, Blood Pressure-Int Consortium, Million Vet Program
Published 2019

Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals

by Dastani, Z., Hivert, M.F., Timpson, N., Perry, J.R.B., Yuan, X., Scott, R.A., Henneman, P., Heid, I.M., Kizer, J.R., Lyytikainen, L.P., Fuchsberger, C., Tanaka, T., Morris, A.P., Small, K., Isaacs, A., Beekman, M., Coassin, S., Lohman, K., Qi, L., Kanoni, S., Pankow, J.S., Uh, H.W., Wu, Y., Bidulescu, A., Rasmussen-Torvik, L.J., Greenwood, C.M.T., Ladouceur, M., Grimsby, J., Manning, A.K., Liu, C.T., Kooner, J., Mooser, V.E., Vollenweider, P., Kapur, K.A., Chambers, J., Wareham, N.J., Langenberg, C., Frants, R., Willems-vanDijk, K., Oostra, B.A., Willems, S.M., Lamina, C., Winkler, T.W., Psaty, B.M., Tracy, R.P., Brody, J., Chen, I., Viikari, J., Kahonen, M., Pramstaller, P.P., Evans, D.M., St Pourcain, B., Sattar, N., Wood, A.R., Bandinelli, S., Carlson, O.D., Egan, J.M., Bohringer, S., Heemst, D. van, Kedenko, L., Kristiansson, K., Nuotio, M.L., Loo, B.M., Harris, T., Garcia, M., Kanaya, A., Haun, M., Klopp, N., Wichmann, H.E., Deloukas, P., Katsareli, E., Couper, D.J., Duncan, B.B., Kloppenburg, M., Adair, L.S., Borja, J.B., Wilson, J.G., Musani, S., Guo, X.Q., Johnson, T., Semple, R., Teslovich, T.M., Allison, M.A., Redline, S., Buxbaum, S.G., Mohlke, K.L., Meulenbelt, I., Ballantyne, C.M., Dedoussis, G.V., Hu, F.B., Liu, Y.M., Paulweber, B., Spector, T.D., Slagboom, P.E., Ferrucci, L., Jula, A., Perola, M., Raitakari, O., Florez, J.C., Salomaa, V., Eriksson, J.G., Frayling, T.M., Hicks, A.A., Lehtimaki, T., Smith, G.D., Siscovick, D.S., Kronenberg, F., Duijn, C. van, Loos, R.J.F., Waterworth, D.M., Meigs, J.B., Dupuis, J., Richards, J.B., DIAGRAM Consortium, MAGIC Consortium, GLGC Investigators, MuTHER Consortium
Published 2012

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

by Jiang, X., O'Reilly, P.F., Aschard, H., Hsu, Y.H., Richards, J.B., Dupuis, J., Ingelsson, E., Karasik, D., Pilz, S., Berry, D., Kestenbaum, B., Zheng, J.S., Luan, J.N., Sofianopoulou, E., Streeten, E.A., Albanes, D., Lutsey, P.L., Yao, L., Tang, W.H., Econs, M.J., Wallaschofski, H., Volzke, H., Zhou, A., Power, C., McCarthy, M.I., Michos, E.D., Boerwinkle, E., Weinstein, S.J., Freedman, N.D., Huang, W.Y., Schoor, N.M. van, Velde, N. van der, Groot, L.C.P.G.M. de, Enneman, A., Cupples, L.A., Booth, S.L., Vasan, R.S., Liu, C.T., Zhou, Y.H., Ripatti, S., Ohlsson, C., Vandenput, L., Lorentzon, M., Eriksson, J.G., Shea, M.K., Houston, D.K., Kritchevsky, S.B., Liu, Y.M., Lohman, K.K., Ferrucci, L., Peacock, M., Gieger, C., Beekman, M., Slagboom, E., Deelen, J., Heemst, D. van, Kleber, M.E., Marz, W., Boer, I.H. de, Wood, A.C., Rotter, J.I., Rich, S.S., Robinson-Cohen, C., Heijer, M. den, Jarvelin, M.R., Cavadino, A., Joshi, P.K., Wilson, J.F., Hayward, C., Lind, L., Michaelsson, K., Trompet, S., Zillikens, M.C., Uitterlinden, A.G., Rivadeneira, F., Broer, L., Zgaga, L., Campbell, H., Theodoratou, E., Farrington, S.M., Timofeeva, M., Dunlop, M.G., Valdes, A.M., Tikkanen, E., Lehtimaki, T., Lyytikainen, L.P., Kahonen, M., Raitakari, O.T., Mikkila, V., Ikram, M.A., Sattar, N., Jukema, J.W., Wareham, N.J., Langenberg, C., Forouhi, N.G., Gundersen, T.E., Khaw, K.T., Butterworth, A.S., Danesh, J., Spector, T., Wang, T.J., Hypponen, E., Kraft, P., Kiel, D.P.
Published 2018

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

by Mahajan, A., Taliun, D., Thurner, M., Robertson, N.R., Torres, J.M., Rayner, N.W., Payne, A.J., Steinthorsdottir, V., Scott, R.A., Grarup, N., Cook, J.P., Schmidt, E.M., Wuttke, M., Sarnowski, C., Magill, R., Nano, J., Gieger, C., Trompet, S., Lecoeur, C., Preuss, M.H., Prins, B.P., Guo, X.Q., Bielak, L.F., Below, J.E., Bowden, D.W., Chambers, J.C., Kim, Y.J., Ng, M.C.Y., Petty, L.E., Sim, X.L., Zhang, W.H., Bennett, A.J., Bork-Jensen, J., Brummett, C.M., Canouil, M., Kardt, K.U.E., Fischer, K., Kardia, S.L.R., Kronenberg, F., Lall, K., Liu, C.T., Locke, A.E., Luan, J.A., Ntalla, L., Nylander, V., Schonherr, S., Schurmann, C., Yengo, L., Bottinger, E.P., Brandslund, I., Christensen, C., Dedoussis, G., Florez, J.C., Ford, I., France, O.H., Frayling, T.M., Giedraitis, V., Hackinger, S., Hattersley, A.T., Herder, C., Ikram, M.A., Ingelsson, M., Jorgensen, M.E., Jorgensen, T., Kriebel, J., Kuusisto, J., Ligthart, S., Lindgren, C.M., Linneberg, A., Lyssenko, V., Mamakou, V., Meitinger, T., Mohlke, K.L., Morris, A.D., Nadkarni, G., Pankow, J.S., Peters, A., Sattar, N., Stancakova, A., Strauch, K., Taylor, K.D., Thorand, B., Thorleifsson, G., Thorsteinsdottir, U., Tuomilehto, J., Witte, D.R., Dupuis, J., Peyser, P.A., Zeggini, E., Loos, R.J.F., Froguel, P., Ingelsson, E., Lind, L., Groop, L., Laakso, M., Collins, F.S., Jukema, J.W., Palmer, C.N.A., Grallert, H., Metspalu, A., Dehghan, A., Kottgen, A., Abecasis, G.R., Meigs, J.B., Rotter, J.I., Marchini, J., Pedersen, O., Hansen, T., Langenberg, C., Wareham, N.J., Stefansson, K., Gloyn, A.L., Morris, A.P., Boehnke, M., McCarthy, M.I.
Published 2018

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis

by Swerdlow, D.I., Holmes, M.V., Kuchenbaecker, K.B., Engmann, J.E.L., Shah, T., Sofat, R., Guo, Y.R., Chung, C., Peasey, A., Ster, R.P., Mooijaart, S.P., Ireland, H.A., Leusink, M., Langenberg, C., Li, K., Palmen, J., Howard, P., Cooper, J.A., Drenos, F., Hardy, J., Nalls, M.A., Li, Y.R., Lowe, G., Stewart, M., Bielinski, S.J., Peto, J., Timpson, N.J., Gallacher, J., Dunlop, M., Houlston, R., Tomlinson, I., Tzoulaki, I., Luan, J., Boer, J.M.A., Forouhi, N.G., Onland-Moret, N.C., Schouw, Y.T. van der, Schnabel, R.B., Hubacek, J.A., Kubinova, R., Baceviciene, M., Tamosiunas, A., Pajak, A., Topor-Madry, R., Malyutina, S.A., Baldassarre, D., Sennblad, B., Tremoli, E., Faire, U. de, Ferrucci, L., Bandenelli, S., Tanaka, T., Meschia, J.F., Singleton, A., Navis, G., Leach, I.M., Bakker, S.J.L., Gansevoort, R.T., Ford, I., Epstein, S.E., Burnett, M.S., Devaney, J.M., Jukema, J.W., Westendorp, R.G.J., Borst, G.J. de, Graaf, Y. van der, Jong, P.A. de, Maitland-van der Zee, A.H., Klungel, O.H., Boer, A. de, Doevendans, P.A., Stephens, J.W., Eaton, C.B., Robinson, J.G., Manson, J.E., Fowkes, F.G.R., Frayling, T.M., Price, J.F., Whincup, P.H., Morris, R.W., Lawlor, D.A., Smith, G.D., Ben-Shlomo, Y., Redline, S., Lange, L.A., Kumari, M., Wareham, N.J., Verschuren, W.M.M., Benjamin, E.J., Whittaker, J.C., Hamsten, A., Dudbridge, F., Delaney, J.A.C., Wong, A., Kuh, D., Hardy, R., Castillo, B.A., Connolly, J.J., Harst, P. van der, Brunner, E.J., Marmot, M.G., Wassel, C.L., Humphries, S.E., Talmud, P.J., Kivimaki, M., Asselbergs, F.W., Voevoda, M., Bobak, M., Pikhart, H., Wilson, J.G., Hakonarson, H., Reiner, A.P., Keating, B.J., Sattar, N., Hingorani, A.D., Casas, J.P., Interleukin-6 Receptor Mendelian R
Published 2012

KLB is associated with alcohol drinking, and its gene product beta-Klotho is necessary for FGF21 regulation of alcohol preference

by Schumann, G., Liu, C.Y., O'Reilly, P., Gao, H., Song, P., Xu, B., Ruggeri, B., Amin, N., Jia, T., Preis, S., Lepe, M.S., Akira, S., Barbieri, C., Baumeister, S., Cauchi, S., Clarke, T.K., Enroth, S., Fischer, K., Hallfors, J., Harris, S.E., Hieber, S., Hofer, E., Hottenga, J.J., Johansson, A., Joshi, P., Kaartinen, N., Laitinen, J., Lemaitre, R., Loukola, A., Luan, J., Lyytikainen, L.P., Mangino, M., Manichaikul, A., Mbarek, H., Milaneschi, Y., Moayyeri, A., Mukamal, K., Nelson, C., Nettleton, J., Partinen, E., Rawal, R., Robino, A., Rose, L., Sala, C., Satoh, T., Schmidt, R., Schrautz, K., Scott, R., Smith, A.V., Starr, J.M., Teumer, A., Trompet, S., Uitterlinden, A.G., Venturini, C., Vergnaud, A.C., Verweij, N., Vitart, V., Vuckovic, D., Wedenoja, J., Yengo, L., Yu, B., Zhang, W., Zhao, J.H., Boomsma, D.I., Chambers, J., Chasman, D.I., Daniela, T., Geus, E. de, Deary, I., Eriksson, J.G., Esko, T., Eulenburg, V., Franco, O.H., Froguel, P., Gieger, C., Grabe, H.J., Gudnason, V., Gyllensten, U., Harris, T.B., Hartikainen, A.L., Heath, A.C., Hocking, L., Hofman, A., Huth, C., Jarvelin, M.R., Jukema, J.W., Kaprio, J., Kooner, J.S., Kutalik, Z., Lahti, J., Langenberg, C., Lehtimaki, T., Liu, Y., Madden, P.A.F., Martin, N., Morrison, A., Penninx, B., Pirastu, N., Psaty, B., Raitakari, O., Ridker, P., Rose, R., Rotter, J.I., Samani, N.J., Schmidt, H., Spector, T.D., Stott, D., Strachan, D., Tzoulaki, I., Harst, P. van der, Duijn, C.M. van, Marques-Vidal, P., Vollenweider, P., Wareham, N.J., Whitfield, J.B., Wilson, J., Wolffenbuttel, B., Bakalkin, G., Evangelou, E., Rice, K.M., Desrivieres, S., Kliewer, S.A., Mangelsdorf, D.J., Muller, C.P., Levy, D., Elliott, P.
Published 2016

Genetic architecture of host proteins involved in SARS-CoV-2 infection

by Pietzner, Maik, Wheeler, E, Carrasco-Zanini, J, Raffler, J, Kerrison, ND, Oerton, E, Au Yeung, V, Luan, J, Finan, C, Casas, JP, Ostroff, R, Williams, SA, Kastenmüller, G, Ralser, M, Gamazon, ER, Wareham, NJ, Hingorani, AD, Langenberg, C
Published 2020

Genome-wide association study meta-analysis for quantitative ultrasound parameters of bone identifies five novel loci for broadband ultrasound attenuation

by Mullin, BH, Zhao, JH, Brown, SJ, Perry, JRB, Luan, J, Zheng, HF, Langenberg, C, Dudbridge, F, Scott, RA, Wareham, NJ, Spector, TD, Richards, JB, Walsh, JP, Wilson, SG
Published 2017

Genomic analysis of diet composition finds novel loci and associations with health and lifestyle

by Meddens, S.F.W., Vlaming, R. de, Bowers, P., Burik, C.A.P., Linner, R.K., Lee, C., Okbay, A., Turley, P., Rietveld, C.A., Fontana, M.A., Ghanbari, M., Imamura, F., McMahon, G., Most, P.J. van der, Voortman, T., Wade, K.H., Anderson, E.L., Braun, K.V.E., Emmett, P.M., Esko, T., Gonzalez, J.R., Kiefte-de Jong, J.C., Langenberg, C., Luan, J., Muka, T., Ring, S., Rivadeneira, F., Snieder, H., Rooij, F.J.A. van, Wolffenbuttel, B.H.R., Smith, G.D., Franco, O.H., Forouhi, N.G., Ikram, M.A., Uitterlinden, A.G., Vliet-Ostaptchouk, J.V. van, Wareham, N.J., Cesarini, D., Harden, K.P., Lee, J.J., Benjamin, D.J., Chow, C.C., Koellinger, P.D., 23andMe Res Team, EPIC-InterAct Consortium, Lifelines Cohort Study
Published 2020