Pleiotropic effects on lipid levels and obesity identified in multi-trait meta-analysis of genome-wide association studies (GWAS) of type 2 diabetes related traits

by Lagou, V., Magi, R., Surakka, I., Sarin, A.P., Horikoshi, M., Thorleifsson, G., Hagg, S., Beekman, M., Ladenvall, C., Hottenga, J.J., Ried, J.S., McCarthy, M.I., Morris, A., Ripatti, S., Prokopenko, I.
Published 2013

A Common Variant in TFB1M Is Associated with Reduced Insulin Secretion and Increased Future Risk of Type 2 Diabetes

by Koeck, T., Olsson, A.H., Nitert, M.D., Sharoyko, V.V., Ladenvall, C., Kotova, O., Reiling, E., Ronn, T., Parikh, H., Taneera, J., Eriksson, J.G., Metodiev, M.D., Larsson, N.G., Balhuizen, A., Luthman, H., Stancakova, A., Kuusisto, J., Laakso, M., Poulsen, P., Vaag, A., Groop, L., Lyssenko, V., Mulder, H., Ling, C.
Published 2011

Distribution and Medical Impact of Loss-of-Function Variants in the Finnish Founder Population

by Lim E.T., Würtz P., Havulinna A.S., Palta P., Tukiainen T., Rehnström K., Esko T., Mägi R., Inouye M., Lappalainen T., Chan Y., Salem R.M., Lek M., Flannick J., Sim X., Manning A., Ladenvall C., Bumpstead S., Hämäläinen E., Aalto K., Maksimow M., Salmi M., Blankenberg S., Ardissino D., Shah S., Horne B., McPherson R., Hovingh G.K., Reilly M.P., Watkins H., Goel A., Farrall M., Girelli D., Reiner A.P., Stitziel N.O., Kathiresan S., Gabriel S., Barrett J.C., Lehtimäki T., Laakso M., Groop L., Kaprio J., Perola M., McCarthy M.I., Boehnke M., Altshuler D.M., Lindgren C.M., Hirschhorn J.N., Metspalu A., Freimer N.B., Zeller T., Jalkanen S., Koskinen S., Raitakari O., Durbin R., MacArthur D.G., Salomaa V., Ripatti S., Daly M.J., Palotie A.
Published 2018

Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation

by Horikoshi, M., Magi, R., Bunt, M. van de, Surakka, I., Sarin, A.P., Mahajan, A., Marullo, L., Thorleifsson, G., Hagg, S., Hottenga, J.J., Ladenvall, C., Ried, J.S., Winkler, T.W., Willems, S.M., Pervjakova, N., Esko, T., Beekman, M., Nelson, C.P., Willenborg, C., Wiltshire, S., Ferreira, T., Fernandez, J., Gaulton, K.J., Steinthorsdottir, V., Hamsten, A., Magnusson, P.K.E., Willemsen, G., Milaneschi, Y., Robertson, N.R., Groves, C.J., Bennett, A.J., Lehtimaki, T., Viikari, J.S., Rung, J., Lyssenko, V., Perola, M., Heid, I.M., Herder, C., Grallert, H., Muller-Nurasyid, M., Roden, M., Hypponen, E., Isaacs, A., Leeuwen, E.M. van, Karssen, L.C., Mihailov, E., Houwing-Duistermaat, J.J., Craen, A.J.M. de, Deelen, J., Havulinna, A.S., Blades, M., Hengstenberg, C., Erdmann, J., Schunkert, H., Kaprio, J., Tobin, M.D., Samani, N.J., Lind, L., Salomaa, V., Lindgren, C.M., Slagboom, P.E., Metspalu, A., Duijn, C.M. van, Eriksson, J.G., Peters, A., Gieger, C., Jula, A., Groop, L., Raitakari, O.T., Power, C., Penninx, B.W.J.H., Geus, E. de, Smit, J.H., Boomsma, D.I., Pedersen, N.L., Ingelsson, E., Thorsteinsdottir, U., Stefansson, K., Ripatti, S., Prokopenko, I., McCarthy, M.I., Morris, A.P., Engage Consortium
Published 2015

The impact of low-frequency and rare variants on lipid levels

by Surakka, I., Horikoshi, M., Magi, R., Sarin, A.P., Mahajan, A., Lagou, V., Marullo, L., Ferreira, T., Miraglio, B., Timonen, S., Kettunen, J., Pirinen, M., Karjalainen, J., Thorleifsson, G., Hagg, S., Hottenga, J.J., Isaacs, A., Ladenvall, C., Beekman, M., Esko, T., Ried, J.S., Nelson, C.P., Willenborg, C., Gustafsson, S., Westra, H.J., Blades, M., Craen, A.J.M. de, Geus, E.J. de, Deelen, J., Grallert, H., Hamsten, A., Havulinna, A.S., Hengstenberg, C., Houwing-Duistermaat, J.J., Hypponen, E., Karssen, L.C., Lehtimaki, T., Lyssenko, V., Magnusson, P.K.E., Mihailov, E., Muller-Nurasyid, M., Mpindi, J.P., Pedersen, N.L., Penninx, B.W.J.H., Perola, M., Pers, T.H., Peters, A., Rung, J., Smit, J.H., Steinthorsdottir, V., Tobin, M.D., Tsernikova, N., Leeuwen, E.M. van, Viikari, J.S., Willems, S.M., Willemsen, G., Schunkert, H., Erdmann, J., Samani, N.J., Kaprio, J., Lind, L., Gieger, C., Metspalu, A., Slagboom, P.E., Groop, L., Duijn, C.M. van, Eriksson, J.G., Jula, A., Salomaa, V., Boomsma, D.I., Power, C., Raitakari, O.T., Ingelsson, E., Jarvelin, M.R., Thorsteinsdottir, U., Franke, L., Ikonen, E., Kallioniemi, O., Pietiainen, V., Lindgren, C.M., Stefansson, K., Palotie, A., McCarthy, M.I., Morris, A.P., Prokopenko, I., Ripatti, S., ENGAGE Consortium
Published 2015

New Susceptibility Loci Associated with Kidney Disease in Type 1 Diabetes

by Sandholm N., Salem R.M., McKnight A.J., Brennan E.P., Forsblom C., Isakova T., McKay G.J., Williams W.W., Sadlier D.M., Mäkinen V.-P., Swan E.J., Palmer C., Boright A.P., Ahlqvist E., Deshmukh H.A., Keller B.J., Huang H., Ahola A.J., Fagerholm E., Gordin D., Harjutsalo V., He B., Heikkilä O., Hietala K., Kytö J., Lahermo P., Lehto M., Lithovius R., Österholm A.-M., Parkkonen M., Pitkäniemi J., Rosengård-Bärlund M., Saraheimo M., Sarti C., Söderlund J., Soro-Paavonen A., Syreeni A., Thorn L.M., Tikkanen H., Tolonen N., Tryggvason K., Tuomilehto J., Wadén J., Gill G.V., Prior S., Guiducci C., Mirel D.B., Taylor A., Hosseini S.M., Parving H.-H., Rossing P., Tarnow L., Ladenvall C., Alhenc-Gelas F., Lefebvre P., Rigalleau V., Roussel R., Tregouet D.-A., Maestroni A., Maestroni S., Falhammar H., Gu T., Möllsten A., Cimponeriu D., Ioana M., Mota M., Mota E., Serafinceanu C., Stavarachi M., Hanson R.L., Nelson R.G., Kretzler M., Colhoun H.M., Panduru N.M., Gu H.F., Brismar K., Zerbini G., Hadjadj S., Marre M., Groop L., Lajer M., Bull S.B., Waggott D., Paterson A.D., Savage D.A., Bain S.C., Martin F., Hirschhorn J.N., Godson C., Florez J.C., Groop P.-H., Maxwell A.P., Böger C.A.
Published 2019

Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes

by Albrechtsen, A., Grarup, N., Li, Y., Sparso, T., Tian, G., Cao, H., Jiang, T., Kim, S.Y., Korneliussen, T., Li, Q., Nie, C., Wu, R., Skotte, L., Morris, A.P., Ladenvall, C., Cauchi, S., Stancakova, A., Andersen, G., Astrup, A., Banasik, K., Bennett, A.J., Bolund, L., Charpentier, G., Chen, Y., Dekker, J.M., Doney, A.S.F., Dorkhan, M., Forsen, T., Frayling, T.M., Groves, C.J., Gui, Y., Hallmans, G., Hattersley, A.T., He, K., Hitman, G.A., Holmkvist, J., Huang, S., Jiang, H., Jin, X., Justesen, J.M., Kristiansen, K., Kuusisto, J., Lajer, M., Lantieri, O., Li, W., Liang, H., Liao, Q., Liu, X., Ma, T., Ma, X., Manijak, M.P., Marre, M., Mokrosinski, J., Morris, A.D., Mu, B., Nielsen, A.A., Nijpels, G., Nilsson, P., Palmer, C.N.A., Rayner, N.W., Renstrom, F., Ribel-Madsen, R., Robertson, N., Rolandsson, O., Rossing, P., Schwartz, T.W., Slagboom, P.E., Sterner, M., Tang, M., Tarnow, L., Tuomi, T., van't Riet, E., Leeuwen, N. van, Varga, T.V., Vestmar, M.A., Walker, M., Wang, B., Wang, Y., Wu, H., Xi, F., Yengo, L., Yu, C., Zhang, X., Zhang, J., Zhang, Q., Zhang, W., Zheng, H., Zhou, Y., Altshuler, D., Hart, L.M. 't, Franks, P.W., Balkau, B., Froguel, P., McCarthy, M.I., Laakso, M., Groop, L., Christensen, C., Brandslund, I., Lauritzen, T., Witte, D.R., Linneberg, A., Jorgensen, T., Hansen, T., Wang, J., Nielsen, R., Pedersen, O., DESIR Study Grp, DIAGRAM Consortium
Published 2013

The Association of Mitochondrial Content with Prevalent and Incident Type 2 Diabetes

by Reiling, E., Ling, C., Uitterlinden, A.G., van't Riet, E., Welschen, L.M.C., Ladenvall, C., Almgren, P., Lyssenko, V., Nijpels, G., Hove, E.C. van, Maassen, J.A., Geus, E.J.C. de, Boomsma, D.I., Dekker, J.M., Groop, L., Willemsen, G., Hart, L.M. 't
Published 2010

The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis

by Fall T., Hägg S., Mägi R., Ploner A., Fischer K., Horikoshi M., Sarin A.-P., Thorleifsson G., Ladenvall C., Kals M., Kuningas M., Draisma H.H.M., Ried J.S., van Zuydam N.R., Huikari V., Mangino M., Sonestedt E., Benyamin B., Nelson C.P., Rivera N.V., Kristiansson K., Shen H.-y., Havulinna A.S., Dehghan A., Donnelly L.A., Kaakinen M., Nuotio M.-L., Robertson N., de Bruijn R.F.A.G., Ikram M.A., Amin N., Balmforth A.J., Braund P.S., Doney A.S.F., Döring A., Elliott P., Esko T., Franco O.H., Gretarsdottir S., Hartikainen A.-L., Heikkilä K., Herzig K.-H., Holm H., Hottenga J.J., Hyppönen E., Illig T., Isaacs A., Isomaa B., Karssen L.C., Kettunen J., Koenig W., Kuulasmaa K., Laatikainen T., Laitinen J., Lindgren C., Lyssenko V., Läärä E., Rayner N.W., Männistö S., Pouta A., Rathmann W., Rivadeneira F., Ruokonen A., Savolainen M.J., Sijbrands E.J.G., Small K.S., Smit J.H., Steinthorsdottir V., Syvänen A.-C., Taanila A., Tobin M.D., Uitterlinden A.G., Willems S.M., Willemsen G., Witteman J., Perola M., Evans A., Ferrières J., Virtamo J., Kee F., Tregouet D.-A., Arveiler D., Amouyel P., Ferrario M.M., Brambilla P., Hall A.S., Heath A.C., Madden P.A.F., Martin N.G., Montgomery G.W., Whitfield J.B., Jula A., Knekt P., Oostra B., van Duijn C.M., Penninx B.W.J.H., Davey Smith G., Kaprio J., Samani N.J., Gieger C., Peters A., Wichmann H.-E., Boomsma D.I., de Geus E.J.C., Tuomi T.M., Power C., Hammond C.J., Spector T.D., Lind L., Orho-Melander M., Palmer C.N.A., Morris A.D., Groop L., Järvelin M.-R., Salomaa V., Vartiainen E., Hofman A., Ripatti S., Metspalu A., Thorsteinsdottir U., Stefansson K., Pedersen N.L., McCarthy M.I., Ingelsson E., Prokopenko I.
Published 2019

The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis

by Fall, T., Hagg, S., Magi, R., Ploner, A., Fischer, K., Horikoshi, M., Sarin, A.P., Thorleifsson, G., Ladenvall, C., Kals, M., Kuningas, M., Draisma, H.H.M., Ried, J.S., Zuydam, N.R. van, Huikari, V., Mangino, M., Sonestedt, E., Benyamin, B., Nelson, C.P., Rivera, N.V., Kristiansson, K., Shen, H.Y., Havulinna, A.S., Dehghan, A., Donnelly, L.A., Kaakinen, M., Nuotio, M.L., Robertson, N., Bruijn, R.F.A.G. de, Ikram, M.A., Amin, N., Balmforth, A.J., Braund, P.S., Doney, A.S.F., Doring, A., Elliott, P., Esko, T., Franco, O.H., Gretarsdottir, S., Hartikainen, A.L., Heikkila, K., Herzig, K.H., Holm, H., Hottenga, J.J., Hypponen, E., Illig, T., Isaacs, A., Isomaa, B., Karssen, L.C., Kettunen, J., Koenig, W., Kuulasmaa, K., Laatikainen, T., Laitinen, J., Lindgren, C., Lyssenko, V., Laara, E., Rayner, N.W., Mannisto, S., Pouta, A., Rathmann, W., Rivadeneira, F., Ruokonen, A., Savolainen, M.J., Sijbrands, E.J.G., Small, K.S., Smit, J.H., Steinthorsdottir, V., Syvanen, A.C., Taanila, A., Tobin, M.D., Uitterlinden, A.G., Willems, S.M., Willemsen, G., Witteman, J., Perola, M., Evans, A., Ferrieres, J., Virtamo, J., Kee, F., Tregouet, D.A., Arveiler, D., Amouyel, P., Ferrario, M.M., Brambilla, P., Hall, A.S., Heath, A., Madden, P.A.F., Martin, N.G., Montgomery, G.W., Whitfield, J.B., Jula, A., Knekt, P., Oostra, B., Duijn, C.M. van, Penninx, B.W.J.H., Smith, G.D., Kaprio, J., Samani, N.J., Gieger, C., Peters, A., Wichmann, H.E., Boomsma, D.I., Geus, E.J.C. de, Tuomi, T., Power, C., Hammond, C.J., Spector, T.D., Lind, L., Orho-Melander, M., Palmer, C.N.A., Morris, A.D., Groop, L., Jarvelin, M.R., Salomaa, V., Vartiainen, E., Hofman, A., Ripatti, S., Metspalu, A., Thorsteinsdottir, U., Stefansson, K., Pedersen, N.L., McCarthy, M.I., Ingelsson, E., Prokopenko, I., ENGAGE Consortium
Published 2013

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis

by Wheeler E., Leong A., Liu C.-T., Hivert M.-F., Strawbridge R.J., Podmore C., Li M., Yao J., Sim X., Hong J., Chu A.Y., Pereira M.A., Peters A., Ridker P.M., Sabanayagam C., Sale M., Saleheen D., Saltevo J., Schwarz P.E.H., Sheu W.H.H., Chang L.-C., Müller-Nurasyid M., Snieder H., Spector T.D., Tabara Y., Tuomilehto J., van Dam R.M., Wilson J.G., Wilson J.F., Wolffenbuttel B.H.R., Chen W.-M., Elks C.E., Nagaraja R., Evans D.S., Fan Q., Giulianini F., Go M.J., Hottenga J.-J., Hu Y., Jackson A.U., Kanoni S., Kim Y.J., Kleber M.E., Nauck M., Ladenvall C., Lecoeur C., Lim S.-H., Lu Y., Mahajan A., Marzi C., Nalls M.A., Navarro P., Nolte I.M., Rose L.M., Pankow J.S., Rybin D.V., Sanna S., Shi Y., Stram D.O., Takeuchi F., Tan S.P., van der Most P.J., Van Vliet-Ostaptchouk J.V., Wong A., Yengo L., Polasek O., Zhao W., Goel A., Martinez Larrad M.T., Radke D., Salo P., Tanaka T., van Iperen E.P.A., Abecasis G., Afaq S., Alizadeh B.Z., Prokopenko I., Bertoni A.G., Bonnefond A., Böttcher Y., Bottinger E.P., Campbell H., Carlson O.D., Chen C.-H., Cho Y.S., Garvey W.T., Gieger C., Ramos P.S., Goodarzi M.O., Grallert H., Hamsten A., Hartman C.A., Herder C., Hsiung C.A., Huang J., Igase M., Isono M., Katsuya T., Rasmussen-Torvik L., Khor C.-C., Kiess W., Kohara K., Kovacs P., Lee J., Lee W.-J., Lehne B., Li H., Liu J., Lobbens S., Rathmann W., Luan J., Lyssenko V., Meitinger T., Miki T., Miljkovic I., Moon S., Mulas A., Müller G., Rich S.S., Zhang W., Robertson N.R., Roden M., Roussel R., Rudan I., Scott R.A., Scott W.R., Sennblad B., Siscovick D.S., Strauch K., Sun L., Wang X., Swertz M., Tajuddin S.M., Taylor K.D., Teo Y.-Y., Tham Y.C., Tönjes A., Wareham N.J., Willemsen G., Wilsgaard T., Hingorani A.D., Chen P., Egan J., Ferrucci L., Hovingh G.K., Jula A., Kivimaki M., Kumari M., Njølstad I., Palmer C.N.A., Serrano Ríos M., Stumvoll M., Maruthur N.M., Watkins H., Aung T., Blüher M., Boehnke M., Boomsma D.I., Bornstein S.R., Chambers J.C., Chasman D.I., Chen Y.-D.I., Chen Y.-T., Porneala B.C., Cheng C.-Y., Cucca F., de Geus E.J.C., Deloukas P., Evans M.K., Fornage M., Friedlander Y., Froguel P., Groop L., Gross M.D., Sharp S.J., Harris T.B., Hayward C., Heng C.-K., Ingelsson E., Kato N., Kim B.-J., Koh W.-P., Kooner J.S., Körner A., Kuh D., Jia Y., Kuusisto J., Laakso M., Lin X., Liu Y., Loos R.J.F., Magnusson P.K.E., März W., McCarthy M.I., Oldehinkel A.J., Ong K.K., Kabagambe E.K., Pedersen N.L.
Published 2020

Exome Sequencing-Driven Discovery of Coding Polymorphisms Associated with Common Metabolic Phenotypes

by Albrechtsen, A., Grarup, N., Sparsø, T., Korneliussen, T., Nie, C., Skotte, L., Ladenvall, C., Cauchi, S., Stančáková, A., Andersen, G., Astrup, A., Banasik, K., Bolund, L., Charpentier, G., Doney, A. S. F., Dorkhan, M., Forsen, T., Frayling, T. M., Groves, C. J., Hallmans, G., Hattersley, A. T., Hitman, G. A., Holmkvist, J., Justesen, J. M., Kristiansen, K., Kuusisto, J., Lajer, M., Lantieri, O., Liao, Q., Manijak, M. P., Marre, M., Mokrosiński, J., Mu, B., Nijpels, G., Nilsson, P., Rayner, N. W., Renström, F., Ribel-Madsen, R., Rolandsson, O., Rossing, P., Schwartz, T. W., Slagboom, P. E., Sterner, M., Tarnow, L., Tuomi, T., van’t Riet, E., van Leeuwen, N., Varga, T. V., Vestmar, M. A., Xi, F., Yengo, L., ‘t Hart, L. M., Balkau, B., Froguel, P., Laakso, M., Groop, L., Brandslund, I., Lauritzen, T., Witte, D. R., Linneberg, A., Jørgensen, T., Pedersen, O., Altshuler, David Matthew, Franks, P. W., Li, Y., Tian, G., Cao, H., Jiang, T., Kim, S. Y., Li, Q., Wu, R., Morris, A. P., Bennett, A. J., Chen, Y., Dekker, J. M., Gui, Y., He, K., Huang, S., Jiang, H., Jin, X., Li, W., Liang, H., Liu, X., Ma, T., Ma, X., Morris, A. D., Nielsen, A. A., Palmer, C. N. A., Robertson, N., Tang, M., Walker, M., Wang, B., Wang, Y., Wu, H., Yu, C., Zhang, X., Zhang, J., Zhang, Q., Zhang, W., Zheng, H., Zhou, Y., McCarthy, M. I., Christensen, C., Hansen, T., Wang, J., Nielsen, R.
Published 2013

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

by Manning, A.K., Hivert, M.F., Scott, R.A., Grimsby, J.L., Bouatia-Naji, N., Chen, H., Rybin, D., Liu, C.T., Bielak, L.F., Prokopenko, I., Amin, N., Barnes, D., Cadby, G., Hottenga, J.J., Ingelsson, E., Jackson, A.U., Johnson, T., Kanoni, S., Ladenvall, C., Lagou, V., Lahti, J., Lecoeur, C., Liu, Y.M., Martinez-Larrad, M.T., Montasser, M.E., Navarro, P., Perry, J.R.B., Rasmussen-Torvik, L.J., Salo, P., Sattar, N., Shungin, D., Strawbridge, R.J., Tanaka, T., Duijn, C.M. van, An, P., Andrade, M. de, Andrews, J.S., Aspelund, T., Atalay, M., Aulchenko, Y., Balkau, B., Bandinelli, S., Beckmann, J.S., Beilby, J.P., Bellis, C., Bergman, R.N., Blangero, J., Boban, M., Boehnke, M., Boerwinkle, E., Bonnycastle, L.L., Boomsma, D.I., Borecki, I.B., Boettcher, Y., Bouchard, C., Brunner, E., Budimir, D., Campbell, H., Carlson, O., Chines, P.S., Clarke, R., Collins, F.S., Corbaton-Anchuelo, A., Couper, D., Faire, U. de, Dedoussis, G.V., Deloukas, P., Dimitriou, M., Egan, J.M., Eiriksdottir, G., Erdos, M.R., Eriksson, J.G., Eury, E., Ferrucci, L., Ford, I., Forouhi, N.G., Fox, C.S., Franzosi, M.G., Franks, P.W., Frayling, T.M., Froguel, P., Galan, P., Geus, E. de, Gigante, B., Glazer, N.L., Goel, A., Groop, L., Gudnason, V., Hallmans, G., Hamsten, A., Hansson, O., Harris, T.B., Hayward, C., Heath, S., Hercberg, S., Hicks, A.A., Hingorani, A., Hofman, A., Hui, J., Hung, J., Jarvelin, M.R., Jhun, M.A., Johnson, P.C.D., Jukema, J.W., Jula, A., Kao, W.H., Kaprio, J., Kardia, S.L.R., Keinanen-Kiukaanniemi, S., Kivimaki, M., Kolcic, I., Kovacs, P., Kumari, M., Kuusisto, J., Kyvik, K.O., Laakso, M., Lakka, T., Lannfelt, L., Lathrop, G.M., Launer, L.J., Leander, K., Li, G., Lind, L., Lindstrom, J., Lobbens, S., Loos, R.J.F., Luan, J.A., Lyssenko, V., Magi, R., Magnusson, P.K.E., Marmot, M., Meneton, P., Mohlke, K.L., Mooser, V., Morken, M.A., Miljkovic, I., Narisu, N., O'Connell, J., Ong, K.K., Oostra, B.A., Palmer, L.J., Palotie, A., Pankow, J.S., Peden, J.F., Pedersen, N.L., Pehlic, M., Peltonen, L., Penninx, B., Pericic, M., Perola, M., Perusse, L., Peyser, P.A., Polasek, O., Pramstaller, P.P., Province, M.A., Raikkonen, K., Rauramaa, R., Rehnberg, E., Rice, K., Rotter, J.I., Rudan, I., Ruokonen, A., Saaristo, T., Sabater-Lleal, M., Salomaa, V., Savage, D.B., Saxena, R., Schwarz, P., Seedorf, U., Sennblad, B., Serrano-Rios, M., Shuldiner, A.R., Sijbrands, E.J.G., Siscovick, D.S., Smit, J.H., Small, K.S., Smith, N.L., Smith, A.V., Stancakova, A., Stirrups, K., Stumvoll, M., Sun, Y.V., Swift, A.J., Toenjes, A., Tuomilehto, J., Trompet, S., Uitterlinden, A.G., Uusitupa, M., Vikstrom, M., Vitart, V., Vohl, M.C., Voight, B.F., Vollenweider, P., Waeber, G., Waterworth, D.M., Watkins, H., Wheeler, E., Widen, E., Wild, S.H., Willems, S.M., Willemsen, G., Wilson, J.F., Witteman, J.C.M., Wright, A.F., Yaghootkar, H., Zelenika, D., Zemunik, T., Zgaga, L., Wareham, N.J., McCarthy, M.I., Barroso, I., Watanabe, R.M., Florez, J.C., Dupuis, J., Meigs, J.B., Langenberg, C., DIAGRAM Consortium, MUTHER Consortium
Published 2012

Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus

by Mahajan A., SIM XUELING, Ng H.J., Manning A., Rivas M.A., Highland H.M., Locke A.E., Grarup N., Im H.K., Cingolani P., Flannick J., Fontanillas P., Fuchsberger C., Gaulton K.J., Teslovich T.M., Rayner N.W., Robertson N.R., Beer N.L., Rundle J.K., Bork-Jensen J., Ladenvall C., Blancher C., Buck D., Buck G., Burtt N.P., Gabriel S., Gjesing A.P., Groves C.J., Hollensted M., Huyghe J.R., Jackson A.U., Jun G., Justesen J.M., Mangino M., Murphy J., Neville M., Onofrio R., Small K.S., Stringham H.M., Syvänen A.-C., Trakalo J., Abecasis G., Bell G.I., Blangero J., Cox N.J., Duggirala R., Hanis C.L., Seielstad M., Wilson J.G., Christensen C., Brandslund I., Rauramaa R., Surdulescu G.L., Doney A.S.F., Lannfelt L., Linneberg A., Isomaa B., Tuomi T., Jørgensen M.E., Jørgensen T., Kuusisto J., Uusitupa M., Salomaa V., Spector T.D., Morris A.D., Palmer C.N.A., Collins F.S., Mohlke K.L., Bergman R.N., Ingelsson E., Lind L., Tuomilehto J., Hansen T., Watanabe R.M., Prokopenko I., Dupuis J., Karpe F., Groop L., Laakso M., Pedersen O., Florez J.C., Morris A.P., Altshuler D., Meigs J.B., Boehnke M., McCarthy M.I., Lindgren C.M., Gloyn A.L., Abboud H.E., Afzal U., Aguilar D., Arya R., Atzmon G., Aung T., Banks E., Barroso I., Barzilai N., Below J.E., Bharadwaj D., Blackwell T.W., Bonnycastle L.L., Bowden D., Carey J., Carneiro M.O., Chambers J.C., Chan E., Chan J., Chandak G.R., Chen P., Chen Y., Chen H., Cheng C.-Y., Chia K.S., Cho Y.S., Correa A., Curran J.E., Daly M.J., Day-Williams A.G., DeFronzo R.A., DePristo M., Donnelly P.J., Ebrahim S.B., Elliott P., Esko T., Fadista J., Farjoun Y., Farmer A.J., Farook V.S., Fennell T., Ferreira T., Fingerlin T., Forsén T., Fowler S.P., Franks P.W., Frayling T.M., Freedman B.I., Froguel P., Gamazon E.R., Gieger C., Glaser B., Go M.J., Goldstein J.I., Grallert H., Grant G., Green T., Griswold M., Hale D.E., Han B.-G., Hartl C., Hattersley A.T., Hicks P.J., Hodgkiss D., Horikoshi M., Hrabé de Angelis M., Hu C., Hu F.B., Huh I., Kamran Ikram M., Illig T., Jablonski K.A., Jenkinson C.P., Jia W., Kang H.M., Khor C.-C., Kim Y., Kim Y.J., Kim B.-J., Kinnunen L., Kooner J.S., Kravic J., Kriebel J., Kumar A., Kumar S., Kuulasmaa T., Kwon M.-S., Langenberg C., Lauritzen T., Lee S., Lee J., Lee J., Lee J.-Y., Lehman D.M., Lehne B., Levy J.C., Li J., Liang L., Lim W.Y., Lin K.-H., Liu J., Loh M., Ma R.C.W., Ma C., Mägi R., Maguire J., Maxwell T.J., McVean G., Meisinger C., Meitinger T., Melander O., Metspalu A., Mihailov E., Milani L., Moutsianas L., Müller-Nurasyid M., K. Musani S., Nagai Y., Narisu N., Neale B.M., Ng M.C.Y., Nilsson P., O'Rahilly S.P., Orho-Melander M., Owen K.R., Palmer N.D., Park T., Pasko D., Pearson R.D., Perry J.R.B., Peters A., Pollin T.I., Poplin R., Prabhakaran D., Puppala S., Purcell S., Qi L., Qi Q., Roden M., Rolandsson O., Rosengren A.H., Sandhu M., Schwarzmayr T., Scott L.J., Scott R.A., Scott J., Scott W.R., Sehmi J., Shakir K., Sladek R., Smith J.D., Stancáková A., Strauch K., Strom T.M., Swift A., Tai E.S., Tajes J.F., Tan S.-T., Tandon N., Taylor H.A., Jr., Teo Y.Y., Thameem F., Thorand B., van de Bunt M., Varga T.V., Walker M., Wareham N.J., Welch R.P., Wieland T., Wilson G., Sr., Wong T.Y., Wood A.R., Yoon J., Zeggini E., Zhang W.
Published 2018

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis

by Wheeler, E, Leong, A, Liu, C-T, Hivert, M-F, Strawbridge, RJ, Podmore, C, Li, M, Yao, J, Sim, X, Hong, J, Chu, AY, Zhang, W, Wang, X, Chen, P, Maruthur, NM, Porneala, BC, Sharp, SJ, Jia, Y, Kabagambe, EK, Chang, L-C, Chen, W-M, Elks, CE, Evans, DS, Fan, Q, Giulianini, F, Go, MJ, Hottenga, J-J, Hu, Y, Jackson, AU, Kanoni, S, Kim, YJ, Kleber, ME, Ladenvall, C, Lecoeur, C, Lim, S-H, Lu, Y, Mahajan, A, Marzi, C, Nalls, MA, Navarro, P, Nolte, IM, Rose, LM, Rybin, DV, Sanna, S, Shi, Y, Stram, DO, Takeuchi, F, Tan, SP, van der Most, PJ, Van Vliet-Ostaptchouk, JV, Wong, A, Yengo, L, Zhao, W, Goel, A, Martinez Larrad, MT, Radke, D, Salo, P, Tanaka, T, van Iperen, EPA, Abecasis, G, Afaq, S, Alizadeh, BZ, Bertoni, AG, Bonnefond, A, Böttcher, Y, Bottinger, EP, Campbell, H, Carlson, OD, Chen, C-H, Cho, YS, Garvey, WT, Gieger, C, Goodarzi, MO, Grallert, H, Hamsten, A, Hartman, CA, Herder, C, Hsiung, CA, Huang, J, Igase, M, Isono, M, Katsuya, T, Khor, C-C, Kiess, W, Kohara, K, Kovacs, P, Lee, J, Lee, W-J, Lehne, B, Li, H, Liu, J, Lobbens, S, Luan, J, Lyssenko, V, Meitinger, T, Miki, T, Miljkovic, I, Moon, S, Mulas, A, Müller, G, Müller-Nurasyid, M, Nagaraja, R, Nauck, M, Pankow, JS, Polasek, O, Prokopenko, I, Ramos, PS, Rasmussen-Torvik, L, Rathmann, W, Rich, SS, Robertson, NR, Roden, M, Roussel, R, Rudan, I, Scott, RA, Scott, WR, Sennblad, B, Siscovick, DS, Strauch, K, Sun, L, Swertz, M, Tajuddin, SM, Taylor, KD, Teo, Y-Y, Tham, YC, Tönjes, A, Wareham, NJ, Willemsen, G, Wilsgaard, T, Hingorani, AD, EPIC-CVD Consortium, EPIC-InterAct Consortium, Lifelines Cohort Study, Egan, J, Ferrucci, L, Hovingh, GK, Jula, A, Kivimaki, M, Kumari, M, Njølstad, I, Palmer, CNA, Serrano Ríos, M, Stumvoll, M, Watkins, H, Aung, T, Blüher, M, Boehnke, M, Boomsma, DI, Bornstein, SR, Chambers, JC, Chasman, DI, Chen, Y-DI, Chen, Y-T, Cheng, C-Y, Cucca, F, de Geus, EJC, Deloukas, P, Evans, MK, Fornage, M, Friedlander, Y, Froguel, P, Groop, L, Gross, MD, Harris, TB, Hayward, C, Heng, C-K, Ingelsson, E, Kato, N, Kim, B-J, Koh, W-P, Kooner, JS, Körner, A, Kuh, D, Kuusisto, J, Laakso, M, Lin, X, Liu, Y, Loos, RJF, Magnusson, PKE, März, W, McCarthy, MI, Oldehinkel, AJ, Ong, KK, Pedersen, NL, Pereira, MA, Peters, A, Ridker, PM, Sabanayagam, C, Sale, M, Saleheen, D, Saltevo, J, Schwarz, PE, Sheu, WHH, Snieder, H, Spector, TD, Tabara, Y, Tuomilehto, J, van Dam, RM, Wilson, JG, Wilson, JF, Wolffenbuttel, BHR, Wong, TY, Wu, J-Y, Yuan, J-M, Zonderman, AB, Soranzo, N, Guo, X, Roberts, DJ, Florez, JC, Sladek, R, Dupuis, J, Morris, AP, Tai, E-S, Selvin, E, Rotter, JI, Langenberg, C, Barroso, I, Meigs, JB
Published 2017

A Low-Frequency Inactivating Akt2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

by Manning, A, Highland, HM, Gasser, J, Sim, X, Tukiainen, T, Fontanillas, P, Grarup, N, Rivas, MA, Mahajan, A, Locke, AE, Cingolani, P, Pers, TH, Viñuela, A, Brown, AA, Wu, Y, Flannick, J, Fuchsberger, C, Gamazon, ER, Gaulton, KJ, Im, HK, Teslovich, TM, Blackwell, TW, Bork-Jensen, J, Burtt, NP, Chen, Y, Green, T, Hartl, C, Kang, HM, Kumar, A, Ladenvall, C, Ma, C, Moutsianas, L, Pearson, RD, Perry, JRB, Rayner, NW, Robertson, NR, Scott, LJ, van de Bunt, M, Eriksson, JG, Jula, A, Koskinen, S, Lehtimäki, T, Palotie, A, Raitakari, OT, Jacobs, SB, Wessel, J, Chu, AY, Scott, RA, Goodarzi, MO, Blancher, C, Buck, G, Buck, D, Chines, PS, Gabriel, S, Gjesing, AP, Groves, CJ, Hollensted, M, Huyghe, JR, Jackson, AU, Jun, G, Justesen, JM, Mangino, M, Murphy, J, Neville, M, Onofrio, R, Small, KS, Stringham, HM, Trakalo, J, Banks, E, Carey, J, Carneiro, MO, DePristo, M, Farjoun, Y, Fennell, T, Goldstein, JI, Grant, G, Hrabé de Angelis, M, Maguire, J, Neale, BM, Poplin, R, Purcell, S, Schwarzmayr, T, Shakir, K, Smith, JD, Strom, TM, Wieland, T, Lindstrom, J, Brandslund, I, Christensen, C, Surdulescu, GL, Lakka, TA, Doney, ASF, Nilsson, P, Wareham, NJ, Langenberg, C, Varga, TV, Franks, PW, Rolandsson, O, Rosengren, AH, Farook, VS, Thameem, F, Puppala, S, Kumar, S, Lehman, DM, Jenkinson, CP, Curran, JE, Hale, DE, Fowler, SP, Arya, R, DeFronzo, RA, Abboud, HE, Syvänen, A-C, Hicks, PJ, Palmer, ND, Ng, MCY, Bowden, DW, Freedman, BI, Esko, T, Mägi, R, Milani, L, Mihailov, E, Metspalu, A, Narisu, N, Kinnunen, L, Bonnycastle, LL, Swift, A, Pasko, D, Wood, AR, Fadista, J, Pollin, TI, Barzilai, N, Atzmon, G, Glaser, B, Thorand, B, Strauch, K, Peters, A, Roden, M, Müller-Nurasyid, M, Liang, L, Kriebel, J, Illig, T, Grallert, H, Gieger, C, Meisinger, C, Lannfelt, L, Musani, SK, Griswold, M, Taylor, HA, Wilson, G, Correa, A, Oksa, H, Scott, WR, Afzal, U, Tan, S-T, Loh, M, Chambers, JC, Sehmi, J, Kooner, JS, Lehne, B, Cho, YS, Lee, J-Y, Han, B-G, Käräjämäki, A, Qi, Q, Qi, L, Huang, J, Hu, FB, Melander, O, Orho-Melander, M, Below, JE, Aguilar, D, Wong, TY, Liu, J, Khor, C-C, Chia, KS, Lim, WY, Cheng, C-Y, Chan, E, Tai, ES, Aung, T, Linneberg, A, Isomaa, B, Meitinger, T, Tuomi, T, Hakaste, L, Kravic, J, Jørgensen, ME, Lauritzen, T, Deloukas, P, Stirrups, KE, Owen, KR, Farmer, AJ, Frayling, TM, O'Rahilly, SP, Walker, M, Levy, JC, Hodgkiss, D, Hattersley, AT, Kuulasmaa, T, Stančáková, A, Barroso, I, Bharadwaj, D, Chan, J, Chandak, GR, Daly, MJ, Donnelly, PJ, Ebrahim, SB, Elliott, P, Fingerlin, T, Froguel, P, Hu, C, Jia, W, Ma, RCW, McVean, G, Park, T, Prabhakaran, D, Sandhu, M, Scott, J, Sladek, R, Tandon, N, Teo, YY, Zeggini, E, Watanabe, RM, Koistinen, HA, Kesaniemi, YA, Uusitupa, M, Spector, TD, Salomaa, V, Rauramaa, R, Palmer, CNA, Prokopenko, I, Morris, AD, Bergman, RN, Collins, FS, Lind, L, Ingelsson, E, Tuomilehto, J, Karpe, F, Groop, L, Jørgensen, T, Hansen, T, Pedersen, O, Kuusisto, J, Abecasis, G, Bell, GI, Blangero, J, Cox, NJ, Duggirala, R, Seielstad, M, Wilson, JG, Dupuis, J, Ripatti, S, Hanis, CL, Florez, JC, Mohlke, KL, Meigs, JB, Laakso, M, Morris, AP, Boehnke, M, Altshuler, D, McCarthy, MI, Gloyn, AL, Lindgren, CM
Published 2017