Progress towards non-small-cell lung cancer models that represent clinical evolutionary trajectories

by Robert E. Hynds, Kristopher K. Frese, David R. Pearce, Eva Grönroos, Caroline Dive, Charles Swanton
Published 2021-01-01

Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses

by Julianna Blagih, Fabio Zani, Probir Chakravarty, Marc Hennequart, Steven Pilley, Sebastijan Hobor, Andreas K. Hock, Josephine B. Walton, Jennifer P. Morton, Eva Gronroos, Susan Mason, Ming Yang, Iain McNeish, Charles Swanton, Karen Blyth, Karen H. Vousden
Published 2020-01-01

Selective inhibition of cancer cell self-renewal through a Quisinostat-histone H1.0 axis

by Cristina Morales Torres, Mary Y. Wu, Sebastijan Hobor, Elanor N. Wainwright, Matthew J. Martin, Harshil Patel, William Grey, Eva Grönroos, Steven Howell, Joana Carvalho, Ambrosius P. Snijders, Michael Bustin, Dominique Bonnet, Paul D. Smith, Charles Swanton, Michael Howell, Paola Scaffidi
Published 2020-04-01

Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models

by Robert E. Hynds, Ariana Huebner, David R. Pearce, Mark S. Hill, Ayse U. Akarca, David A. Moore, Sophia Ward, Kate H. C. Gowers, Takahiro Karasaki, Maise Al Bakir, Gareth A. Wilson, Oriol Pich, Carlos Martínez-Ruiz, A. S. Md Mukarram Hossain, Simon P. Pearce, Monica Sivakumar, Assma Ben Aissa, Eva Grönroos, Deepak Chandrasekharan, Krishna K. Kolluri, Rebecca Towns, Kaiwen Wang, Daniel E. Cook, Leticia Bosshard-Carter, Cristina Naceur-Lombardelli, Andrew J. Rowan, Selvaraju Veeriah, Kevin Litchfield, Philip A. J. Crosbie, Caroline Dive, Sergio A. Quezada, Sam M. Janes, Mariam Jamal-Hanjani, Teresa Marafioti, TRACERx consortium, Nicholas McGranahan, Charles Swanton
Published 2024-05-01

Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling

by Sebastijan Hobor, Maise Al Bakir, Crispin T. Hiley, Marcin Skrzypski, Alexander M. Frankell, Bjorn Bakker, Thomas B. K. Watkins, Aleksandra Markovets, Jonathan R. Dry, Andrew P. Brown, Jasper van der Aart, Hilda van den Bos, Diana Spierings, Dahmane Oukrif, Marco Novelli, Turja Chakrabarti, Adam H. Rabinowitz, Laila Ait Hassou, Saskia Litière, D. Lucas Kerr, Lisa Tan, Gavin Kelly, David A. Moore, Matthew J. Renshaw, Subramanian Venkatesan, William Hill, Ariana Huebner, Carlos Martínez-Ruiz, James R. M. Black, Wei Wu, Mihaela Angelova, Nicholas McGranahan, Julian Downward, Juliann Chmielecki, Carl Barrett, Kevin Litchfield, Su Kit Chew, Collin M. Blakely, Elza C. de Bruin, Floris Foijer, Karen H. Vousden, Trever G. Bivona, TRACERx consortium, Robert E. Hynds, Nnennaya Kanu, Simone Zaccaria, Eva Grönroos, Charles Swanton
Published 2024-06-01