Checkpoint Blockade in Cancer Immunotherapy: Squaring the Circle

by Maria A.V. Marzolini, Sergio A. Quezada, Karl S. Peggs
Published 2015-03-01

The Great Debate at ‘Immunotherapy Bridge’, Naples, December 5, 2019

by Jerome Galon, Chrystal M Paulos, Sergio A Quezada, Hussein A Tawbi
Published 2020-07-01

Allergens of the urushiol family promote mitochondrial dysfunction by inhibiting the electron transport at the level of cytochromes b and chemically modify cytochrome c1

by Rodrigo Pacheco, Sergio A. Quezada, Alexis M. Kalergis, María Inés Becker, Jorge Ferreira, Alfredo E. De Ioannes
Published 2021-10-01

Correction: Corrigendum: Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis

by Isabel Ohs, Maries van den Broek, Kathrin Nussbaum, Christian Münz, Sebastian J. Arnold, Sergio A. Quezada, Sonia Tugues, Burkhard Becher
Published 2017-04-01

Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis

by Isabel Ohs, Maries van den Broek, Kathrin Nussbaum, Christian Münz, Sebastian J. Arnold, Sergio A. Quezada, Sonia Tugues, Burkhard Becher
Published 2016-12-01

Urokinase-type plasminogen activator (uPA) regulates invasion and matrix remodelling in colorectal cancer

by Auxtine Micalet, Luke J. Tappouni, Katarzyna Peszko, Despoina Karagianni, Ashley Lam, John R. Counsell, Sergio A. Quezada, Emad Moeendarbary, Umber Cheema
Published 2023-12-01

Induction of islet autoimmunity to defective ribosomal product of the insulin gene as neoantigen after anti-cancer immunotherapy leading to autoimmune diabetes

by Rene van Tienhoven, Rene van Tienhoven, Diahann T. S. L. Jansen, Miso Park, John C. Williams, James Larkin, Sergio A. Quezada, Bart O. Roep
Published 2024-03-01

Increased Immune-Regulatory Receptor Expression on Effector T Cells as Early Indicators of Relapse Following Autologous Stem Cell Transplantation for Multiple Myeloma

by Lydia Lee, Nouf Alrasheed, Garima Khandelwal, Evelyn Fitzsimons, Huw Richards, William Wilson, Selina J. Chavda, Jake Henry, Jake Henry, Lucia Conde, Marc Robert De Massy, Marc Robert De Massy, Marc Robert De Massy, Melody Chin, Daria Galas-Filipowicz, Javier Herrero, Benny Chain, Sergio A. Quezada, Sergio A. Quezada, Kwee Yong
Published 2021-02-01

Tissue-resident memory CD8+ T cells amplify anti-tumor immunity by triggering antigen spreading through dendritic cells

by Evelyn Menares, Felipe Gálvez-Cancino, Pablo Cáceres-Morgado, Ehsan Ghorani, Ernesto López, Ximena Díaz, Juan Saavedra-Almarza, Diego A. Figueroa, Eduardo Roa, Sergio A. Quezada, Alvaro Lladser
Published 2019-09-01

1312 Identification and validation of immunogenic clonal neoantigens for personalized therapies

by Andrew Craig, Martin Forster, Samra Turajlic, Sergio A Quezada, Katy Newton, Karl Peggs, Fong Chan, Karen Matthews, Theres Oakes, Gareth Wilson, Elizabeth Larose Cadieux, Max Salm, Hugh O’Brien
Published 2023-11-01

Pan-cancer deconvolution of tumour composition using DNA methylation

by Ankur Chakravarthy, Andrew Furness, Kroopa Joshi, Ehsan Ghorani, Kirsty Ford, Matthew J. Ward, Emma V. King, Matt Lechner, Teresa Marafioti, Sergio A. Quezada, Gareth J. Thomas, Andrew Feber, Tim R. Fenton
Published 2018-08-01

Author Correction: Pan-cancer deconvolution of tumour composition using DNA methylation

by Ankur Chakravarthy, Andrew Furness, Kroopa Joshi, Ehsan Ghorani, Kirsty Ford, Matthew J. Ward, Emma V. King, Matt Lechner, Teresa Marafioti, Sergio A. Quezada, Gareth J. Thomas, Andrew Feber, Tim R. Fenton
Published 2018-11-01

PD-L1 signaling on human memory CD4+ T cells induces a regulatory phenotype.

by Giorgia Fanelli, Marco Romano, Estefania Nova-Lamperti, Mariana Werner Sunderland, Alessandra Nerviani, Cristiano Scottà, Michele Bombardieri, Sergio A Quezada, Steven H Sacks, Randolph J Noelle, Costantino Pitzalis, Robert I Lechler, Giovanna Lombardi, Pablo D Becker
Published 2021-04-01

Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin

by Claudia Garcia-Diaz, Anni Pöysti, Elisabetta Mereu, Melanie P. Clements, Lucy J. Brooks, Felipe Galvez-Cancino, Simon P. Castillo, Wenhao Tang, Gordon Beattie, Lilas Courtot, Sara Ruiz, Federico Roncaroli, Yinyin Yuan, Samuel Marguerat, Sergio A. Quezada, Holger Heyn, Simona Parrinello
Published 2023-05-01

Deep cell phenotyping and spatial analysis of multiplexed imaging with TRACERx-PHLEX

by Alastair Magness, Emma Colliver, Katey S. S. Enfield, Claudia Lee, Masako Shimato, Emer Daly, David A. Moore, Monica Sivakumar, Karishma Valand, Dina Levi, Crispin T. Hiley, Philip S. Hobson, Febe van Maldegem, James L. Reading, Sergio A. Quezada, Julian Downward, Erik Sahai, Charles Swanton, Mihaela Angelova
Published 2024-06-01

437 Optimised achilles VELOSTM process 2b manufacturing platform generates a significant dose boost of reactive CD8 and CD4 clonal neoantigen-reactive T cells for the treatment of...

by Sergio A Quezada, Katy Newton, Monica Sassi, Sandro Gomez, Evi Rologi, Meghan Madigan, Joanne Tang, Sarah Thirkell, Samuel Jide Banwo, Temi Ogunleye, Sophie McKeeman, Claire Law, Unnaamalai Meyyappan, Eleni Kotsiou, Theres Oakes, Miha Kosmac, Luke Goodsell, Connor Carolan, Justin Ahern, Tim Hillyer, Bongi Ndlovu, Henrieta Fraser, Edward Samuel
Published 2023-11-01

Escape from nonsense-mediated decay associates with anti-tumor immunogenicity

by Kevin Litchfield, James L. Reading, Emilia L. Lim, Hang Xu, Po Liu, Maise Al-Bakir, Yien Ning Sophia Wong, Andrew Rowan, Samuel A. Funt, Taha Merghoub, David Perkins, Martin Lauss, Inge Marie Svane, Göran Jönsson, Javier Herrero, James Larkin, Sergio A. Quezada, Matthew D. Hellmann, Samra Turajlic, Charles Swanton
Published 2020-07-01

Intratumoral IL-12 delivery empowers CAR-T cell immunotherapy in a pre-clinical model of glioblastoma

by Giulia Agliardi, Anna Rita Liuzzi, Alastair Hotblack, Donatella De Feo, Nicolás Núñez, Cassandra L. Stowe, Ekaterina Friebel, Francesco Nannini, Lukas Rindlisbacher, Thomas A. Roberts, Rajiv Ramasawmy, Iwan P. Williams, Bernard M. Siow, Mark F. Lythgoe, Tammy L. Kalber, Sergio A. Quezada, Martin A. Pule, Sonia Tugues, Karin Straathof, Burkhard Becher
Published 2021-01-01

Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 3rd–5th, 2020, Italy)

by Paolo A. Ascierto, Christian Blank, Reinhard Dummer, Marc S. Ernstoff, Soldano Ferrone, Bernard A. Fox, Thomas F. Gajewski, Claus Garbe, Patrick Hwu, Pawel Kalinski, Michelle Krogsgaard, Roger S. Lo, Jason J. Luke, Bart Neyns, Michael A. Postow, Sergio A. Quezada, Michele W. L. Teng, Giorgio Trinchieri, Alessandro Testori, Corrado Caracò, Iman Osman, Igor Puzanov, Magdalena Thurin
Published 2021-06-01

Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 2nd – 4th, 2021, Italy)

by Paolo A. Ascierto, Sanjiv S. Agarwala, Christian Blank, Corrado Caracò, Richard D. Carvajal, Marc S. Ernstoff, Soldano Ferrone, Bernard A. Fox, Thomas F. Gajewski, Claus Garbe, Jean-Jacques Grob, Omid Hamid, Michelle Krogsgaard, Roger S. Lo, Amanda W. Lund, Gabriele Madonna, Olivier Michielin, Bart Neyns, Iman Osman, Solange Peters, Poulikos I. Poulikakos, Sergio A. Quezada, Bradley Reinfeld, Laurence Zitvogel, Igor Puzanov, Magdalena Thurin
Published 2022-09-01