Loss of PBRM1 rescues VHL dependent replication stress to promote renal carcinogenesis

by Judit Espana-Agusti, Anne Warren, Su Kit Chew, David J. Adams, Athena Matakidou
Published 2017-12-01

Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling

by Sebastijan Hobor, Maise Al Bakir, Crispin T. Hiley, Marcin Skrzypski, Alexander M. Frankell, Bjorn Bakker, Thomas B. K. Watkins, Aleksandra Markovets, Jonathan R. Dry, Andrew P. Brown, Jasper van der Aart, Hilda van den Bos, Diana Spierings, Dahmane Oukrif, Marco Novelli, Turja Chakrabarti, Adam H. Rabinowitz, Laila Ait Hassou, Saskia Litière, D. Lucas Kerr, Lisa Tan, Gavin Kelly, David A. Moore, Matthew J. Renshaw, Subramanian Venkatesan, William Hill, Ariana Huebner, Carlos Martínez-Ruiz, James R. M. Black, Wei Wu, Mihaela Angelova, Nicholas McGranahan, Julian Downward, Juliann Chmielecki, Carl Barrett, Kevin Litchfield, Su Kit Chew, Collin M. Blakely, Elza C. de Bruin, Floris Foijer, Karen H. Vousden, Trever G. Bivona, TRACERx consortium, Robert E. Hynds, Nnennaya Kanu, Simone Zaccaria, Eva Grönroos, Charles Swanton
Published 2024-06-01

Abstract 827: A journey to deconvolute the multifaceted functions and context-dependency of cancer driver genes

by Cai, Hongchen, Chew, Su Kit, Li, Chuan, Murray, Christopher W, Andrejka, Laura, Hebert, Jess D, Tsai, Min K, Tang, Rui, Hughes, Nicholas W, Shuldiner, Emily G, Ashkin, Emily L, Lee, Shi Ya C, Yousefi, Maryam, Petrov, Dmitri A, Swanton, Charles, Winslow, Monte W
Published 2022