Externally-Controlled Systems for Immunotherapy: From Bench to Bedside

by María Tristán-Manzano, Pedro Justicia-Lirio, Pedro Justicia-Lirio, Noelia Maldonado-Pérez, Marina Cortijo-Gutiérrez, Karim Benabdellah, Francisco Martin
Published 2020-09-01

Development of Cellular Models to Study Efficiency and Safety of Gene Edition by Homologous Directed Recombination Using the CRISPR/Cas9 System

by Sabina Sánchez-Hernández, Araceli Aguilar-González, Beatriz Guijarro-Albaladejo, Noelia Maldonado-Pérez, Iris Ramos-Hernández, Marina Cortijo-Gutiérrez, Rosario María Sánchez Martín, Karim Benabdellah, Francisco Martin
Published 2020-06-01

Improved Functionality of Integration-Deficient Lentiviral Vectors (IDLVs) by the Inclusion of IS₂ Protein Docks

by Marina Cortijo-Gutiérrez, Sabina Sánchez-Hernández, María Tristán-Manzano, Noelia Maldonado-Pérez, Lourdes Lopez-Onieva, Pedro J. Real, Concha Herrera, Juan Antonio Marchal, Francisco Martin, Karim Benabdellah
Published 2021-08-01

Genome‐edited adult stem cells: Next‐generation advanced therapy medicinal products

by Karim Benabdellah, Sabina Sánchez‐Hernández, Araceli Aguilar‐González, Noelia Maldonado‐Pérez, Alejandra Gutierrez‐Guerrero, Marina Cortijo‐Gutierrez, Iris Ramos‐Hernández, María Tristán‐Manzano, Pablo Galindo‐Moreno, Concha Herrera, Francisco Martin
Published 2020-06-01

Using Gene Editing Approaches to Fine-Tune the Immune System

by Kristina Pavlovic, Kristina Pavlovic, María Tristán-Manzano, Noelia Maldonado-Pérez, Marina Cortijo-Gutierrez, Sabina Sánchez-Hernández, Pedro Justicia-Lirio, Pedro Justicia-Lirio, M. Dolores Carmona, Concha Herrera, Concha Herrera, Francisco Martin, Karim Benabdellah
Published 2020-09-01

Lentiviral vectors for inducible, transactivator-free advanced therapy medicinal products: Application to CAR-T cells

by María Tristán-Manzano, Noelia Maldonado-Pérez, Pedro Justicia-Lirio, Marina Cortijo-Gutierréz, Pablo Tristán-Ramos, Carlos Blanco-Benítez, Kristina Pavlovic, Araceli Aguilar-González, Pilar Muñoz, Francisco J. Molina-Estevez, Valerie Griesche, Juan Antonio Marchal, Sara R. Heras, Karim Benabdellah, Francisco Martin
Published 2023-06-01

Physiological lentiviral vectors for the generation of improved CAR-T cells

by María Tristán-Manzano, Noelia Maldonado-Pérez, Pedro Justicia-Lirio, Pilar Muñoz, Marina Cortijo-Gutiérrez, Kristina Pavlovic, Rosario Jiménez-Moreno, Sonia Nogueras, M. Dolores Carmona, Sabina Sánchez-Hernández, Araceli Aguilar-González, María Castella, Manel Juan, Concepción Marañón, Juan Antonio Marchal, Karim Benabdellah, Concha Herrera, Francisco Martin
Published 2022-06-01

Physiological lentiviral vectors for the generation of improved CAR-T cells

by María Tristán-Manzano, Noelia Maldonado-Pérez, Pedro Justicia-Lirio, Pilar Muñoz, Marina Cortijo-Gutiérrez, Kristina Pavlovic, Rosario Jiménez-Moreno, Sonia Nogueras, M. Dolores Carmona, Sabina Sánchez-Hernández, Araceli Aguilar-González, María Castella, Manel Juan, Concepción Marañón, Juan Antonio Marchal, Karim Benabdellah, Concha Herrera, Francisco Martin
Published 2022-09-01

Efficacy and safety of universal (TCRKO) ARI-0001 CAR-T cells for the treatment of B-cell lymphoma

by Noelia Maldonado-Pérez, María Tristán-Manzano, María Tristán-Manzano, Pedro Justicia-Lirio, Pedro Justicia-Lirio, Elena Martínez-Planes, Pilar Muñoz, Pilar Muñoz, Kristina Pavlovic, Kristina Pavlovic, Marina Cortijo-Gutiérrez, Carlos Blanco-Benítez, Carlos Blanco-Benítez, María Castella, Manel Juan, Mathias Wenes, Pedro Romero, Francisco J. Molina-Estévez, Concepción Marañón, Concha Herrera, Karim Benabdellah, Francisco Martin, Francisco Martin
Published 2022-10-01

Generating universal anti-CD19 CAR T cells with a defined memory phenotype by CRISPR/Cas9 editing and safety evaluation of the transcriptome

by Kristina Pavlovic, Kristina Pavlovic, MDolores Carmona-Luque, Giulia I. Corsi, Noelia Maldonado-Pérez, Francisco J. Molina-Estevez, Esther Peralbo-Santaella, Marina Cortijo-Gutiérrez, Pedro Justicia-Lirio, María Tristán-Manzano, Víctor Ronco-Díaz, Antonio Ballesteros-Ribelles, Alejandro Millán-López, Paula Heredia-Velázquez, Paula Heredia-Velázquez, Carla Fuster-García, Toni Cathomen, Stefan E. Seemann, Jan Gorodkin, Francisco Martin, Francisco Martin, Francisco Martin, Concha Herrera, Concha Herrera, Concha Herrera, Karim Benabdellah
Published 2024-05-01

Progress and harmonization of gene editing to treat human diseases: Proceeding of COST Action CA21113 GenE-HumDi

by Alessia Cavazza, Ayal Hendel, Rasmus O. Bak, Paula Rio, Marc Güell, Duško Lainšček, Virginia Arechavala-Gomeza, Ling Peng, Fatma Zehra Hapil, Joshua Harvey, Francisco G. Ortega, Coral Gonzalez-Martinez, Carsten W. Lederer, Kasper Mikkelsen, Giedrius Gasiunas, Nechama Kalter, Manuel A.F.V. Gonçalves, Julie Petersen, Alejandro Garanto, Lluis Montoliu, Marcello Maresca, Stefan E. Seemann, Jan Gorodkin, Loubna Mazini, Rosario Sanchez, Juan R. Rodriguez-Madoz, Noelia Maldonado-Pérez, Torella Laura, Michael Schmueck-Henneresse, Cristina Maccalli, Julian Grünewald, Gloria Carmona, Neli Kachamakova-Trojanowska, Annarita Miccio, Francisco Martin, Giandomenico Turchiano, Toni Cathomen, Yonglun Luo, Shengdar Q. Tsai, Karim Benabdellah
Published 2023-12-01