The Black Hole: CAR T Cell Therapy in AML

by Erden Atilla, Karim Benabdellah
Published 2023-05-01

Characterization of Three New Glutaredoxin Genes in the Arbuscular Mycorrhizal Fungus Rhizophagus irregularis: Putative Role of RiGRX4 and RiGRX5 in Iron Homeostasis.

by Elisabeth Tamayo, Karim Benabdellah, Nuria Ferrol
Published 2016-01-01

Failure of ALL recognition by CAR T cells: a review of CD 19-negative relapses after anti-CD 19 CAR-T treatment in B-ALL

by Clara Aparicio-Pérez, MDolores Carmona, MDolores Carmona, Karim Benabdellah, Karim Benabdellah, Concha Herrera, Concha Herrera, Concha Herrera, Concha Herrera
Published 2023-04-01

A chimeric HS4-SAR insulator (IS2) that prevents silencing and enhances expression of lentiviral vectors in pluripotent stem cells.

by Karim Benabdellah, Alejandra Gutierrez-Guerrero, Marién Cobo, Pilar Muñoz, Francisco Martín
Published 2014-01-01

Development of an all-in-one lentiviral vector system based on the original TetR for the easy generation of Tet-ON cell lines.

by Karim Benabdellah, Marién Cobo, Pilar Muñoz, Miguel G Toscano, Francisco Martin
Published 2011-01-01

CRISPR delivery with extracellular vesicles: Promises and challenges

by Anne Højberg Berggreen, Julie Lund Petersen, Lin Lin, Karim Benabdellah, Yonglun Luo
Published 2023-09-01

Biased and Unbiased Methods for the Detection of Off-Target Cleavage by CRISPR/Cas9: An Overview

by Francisco Martin, Sabina Sánchez-Hernández, Alejandra Gutiérrez-Guerrero, Javier Pinedo-Gomez, Karim Benabdellah
Published 2016-09-01

Exosomes: Their Role in Pathogenesis, Diagnosis and Treatment of Diseases

by Houssam Aheget, Loubna Mazini, Francisco Martin, Boutaïna Belqat, Juan Antonio Marchal, Karim Benabdellah
Published 2020-12-01

High-Density Lipoprotein in Metabolic Disorders and Beyond: An Exciting New World Full of Challenges and Opportunities

by Evangelia Zvintzou, Eva Xepapadaki, George Skroubis, Victoria Mparnia, Katerina Giannatou, Karim Benabdellah, Kyriakos E. Kypreos
Published 2023-06-01

The Rhizophagus irregularis Genome Encodes Two CTR Copper Transporters That Mediate Cu Import Into the Cytosol and a CTR-Like Protein Likely Involved in Copper Tolerance

by Tamara Gómez-Gallego, Karim Benabdellah, Miguel A. Merlos, Ana M. Jiménez-Jiménez, Carine Alcon, Pierre Berthomieu, Nuria Ferrol
Published 2019-05-01

Externally-Controlled Systems for Immunotherapy: From Bench to Bedside

by María Tristán-Manzano, Pedro Justicia-Lirio, Pedro Justicia-Lirio, Noelia Maldonado-Pérez, Marina Cortijo-Gutiérrez, Karim Benabdellah, Francisco Martin
Published 2020-09-01

Mesenchymal Stem Cells Expressing Vasoactive Intestinal Peptide Ameliorate Symptoms in a Model of Chronic Multiple Sclerosis

by Marién Cobo, Per Anderson, Karim Benabdellah, Miguel G. Toscano, Pilar Muñoz, Angélica García-Pérez, Iván Gutierrez, Mario Delgado, Francisco Martin
Published 2013-05-01

Use of zinc-finger nucleases to knock out the WAS gene in K562 cells: a human cellular model for Wiskott-Aldrich syndrome

by Miguel G. Toscano, Per Anderson, Pilar Muñoz, Gema Lucena, Marién Cobo, Karim Benabdellah, Philip D. Gregory, Michael C. Holmes, Francisco Martin
Published 2013-03-01

Exosome: A New Player in Translational Nanomedicine

by Houssam Aheget, María Tristán-Manzano, Loubna Mazini, Marina Cortijo-Gutierrez, Pablo Galindo-Moreno, Concha Herrera, Francisco Martin, Juan Antonio Marchal, Karim Benabdellah
Published 2020-07-01

Specific marking of hESCs-derived hematopoietic lineage by WAS-promoter driven lentiviral vectors.

by Pilar Muñoz, Miguel G Toscano, Pedro J Real, Karim Benabdellah, Marién Cobo, Clara Bueno, Verónica Ramos-Mejía, Pablo Menendez, Per Anderson, Francisco Martín
Published 2012-01-01

Gene Therapy Corrects Mitochondrial Dysfunction in Hematopoietic Progenitor Cells and Fibroblasts from Coq9R239X Mice.

by Eliana Barriocanal-Casado, Cristina Cueto-Ureña, Karim Benabdellah, Alejandra Gutiérrez-Guerrero, Marién Cobo, Agustín Hidalgo-Gutiérrez, Juan José Rodríguez-Sevilla, Francisco Martín, Luis C López
Published 2016-01-01

Development of Cellular Models to Study Efficiency and Safety of Gene Edition by Homologous Directed Recombination Using the CRISPR/Cas9 System

by Sabina Sánchez-Hernández, Araceli Aguilar-González, Beatriz Guijarro-Albaladejo, Noelia Maldonado-Pérez, Iris Ramos-Hernández, Marina Cortijo-Gutiérrez, Rosario María Sánchez Martín, Karim Benabdellah, Francisco Martin
Published 2020-06-01

Improved Functionality of Integration-Deficient Lentiviral Vectors (IDLVs) by the Inclusion of IS₂ Protein Docks

by Marina Cortijo-Gutiérrez, Sabina Sánchez-Hernández, María Tristán-Manzano, Noelia Maldonado-Pérez, Lourdes Lopez-Onieva, Pedro J. Real, Concha Herrera, Juan Antonio Marchal, Francisco Martin, Karim Benabdellah
Published 2021-08-01

Genome‐edited adult stem cells: Next‐generation advanced therapy medicinal products

by Karim Benabdellah, Sabina Sánchez‐Hernández, Araceli Aguilar‐González, Noelia Maldonado‐Pérez, Alejandra Gutierrez‐Guerrero, Marina Cortijo‐Gutierrez, Iris Ramos‐Hernández, María Tristán‐Manzano, Pablo Galindo‐Moreno, Concha Herrera, Francisco Martin
Published 2020-06-01

Estradiol and Estrone Have Different Biological Functions to Induce NF-κB-Driven Inflammation, EMT and Stemness in ER+ Cancer Cells

by Ana Belén Diaz-Ruano, Nuria Martinez-Alarcon, Macarena Perán, Karim Benabdellah, María de los Ángeles Garcia-Martinez, Ovidiu Preda, César Ramirez-Tortosa, Andrea Gonzalez-Hernandez, Juan Antonio Marchal, Manuel Picon-Ruiz
Published 2023-01-01