Development of Cellular Models to Study Efficiency and Safety of Gene Edition by Homologous Directed Recombination Using the CRISPR/Cas9 System

by Sabina Sánchez-Hernández, Araceli Aguilar-González, Beatriz Guijarro-Albaladejo, Noelia Maldonado-Pérez, Iris Ramos-Hernández, Marina Cortijo-Gutiérrez, Rosario María Sánchez Martín, Karim Benabdellah, Francisco Martin
Published 2020-06-01

Genome‐edited adult stem cells: Next‐generation advanced therapy medicinal products

by Karim Benabdellah, Sabina Sánchez‐Hernández, Araceli Aguilar‐González, Noelia Maldonado‐Pérez, Alejandra Gutierrez‐Guerrero, Marina Cortijo‐Gutierrez, Iris Ramos‐Hernández, María Tristán‐Manzano, Pablo Galindo‐Moreno, Concha Herrera, Francisco Martin
Published 2020-06-01

Isogenic GAA-KO Murine Muscle Cell Lines Mimicking Severe Pompe Mutations as Preclinical Models for the Screening of Potential Gene Therapy Strategies

by Araceli Aguilar-González, Juan Elías González-Correa, Eliana Barriocanal-Casado, Iris Ramos-Hernández, Miguel A. Lerma-Juárez, Sara Greco, Juan José Rodríguez-Sevilla, Francisco Javier Molina-Estévez, Valle Montalvo-Romeral, Giuseppe Ronzitti, Rosario María Sánchez-Martín, Francisco Martín, Pilar Muñoz
Published 2022-06-01

Lentiviral vectors for inducible, transactivator-free advanced therapy medicinal products: Application to CAR-T cells

by María Tristán-Manzano, Noelia Maldonado-Pérez, Pedro Justicia-Lirio, Marina Cortijo-Gutierréz, Pablo Tristán-Ramos, Carlos Blanco-Benítez, Kristina Pavlovic, Araceli Aguilar-González, Pilar Muñoz, Francisco J. Molina-Estevez, Valerie Griesche, Juan Antonio Marchal, Sara R. Heras, Karim Benabdellah, Francisco Martin
Published 2023-06-01

Physiological lentiviral vectors for the generation of improved CAR-T cells

by María Tristán-Manzano, Noelia Maldonado-Pérez, Pedro Justicia-Lirio, Pilar Muñoz, Marina Cortijo-Gutiérrez, Kristina Pavlovic, Rosario Jiménez-Moreno, Sonia Nogueras, M. Dolores Carmona, Sabina Sánchez-Hernández, Araceli Aguilar-González, María Castella, Manel Juan, Concepción Marañón, Juan Antonio Marchal, Karim Benabdellah, Concha Herrera, Francisco Martin
Published 2022-06-01

Physiological lentiviral vectors for the generation of improved CAR-T cells

by María Tristán-Manzano, Noelia Maldonado-Pérez, Pedro Justicia-Lirio, Pilar Muñoz, Marina Cortijo-Gutiérrez, Kristina Pavlovic, Rosario Jiménez-Moreno, Sonia Nogueras, M. Dolores Carmona, Sabina Sánchez-Hernández, Araceli Aguilar-González, María Castella, Manel Juan, Concepción Marañón, Juan Antonio Marchal, Karim Benabdellah, Concha Herrera, Francisco Martin
Published 2022-09-01