The Immune Microenvironment in Multiple Myeloma Progression at a Single-cell Level

by Carolina Schinke, Niels Weinhold
Published 2023-06-01

Editorial: The role of the bone marrow microenvironment in multiple myeloma evolution and therapy

by Carolina Schinke, Niels Weinhold, Jesus Delgado-Calle
Published 2023-02-01

The Impact of Tumor Heterogeneity on Diagnostics and Novel Therapeutic Strategies in Multiple Myeloma

by Leo Rasche, K. Martin Kortüm, Marc S. Raab, Niels Weinhold
Published 2019-03-01

Therapeutic Advances Propelled by Deciphering Tumor Biology and Immunology—Highlights of the 8th Heidelberg Myeloma Workshop

by Raphael Lutz, Mirco Friedrich, Marc Steffen Raab, Niels Weinhold, Hartmut Goldschmidt
Published 2021-08-01

Stem cell collection after lenalidomide, bortezomib and dexamethasone plus elotuzumab or isatuximab in newly diagnosed multiple myeloma patients: a single centre experience from th...

by Joseph Kauer, Emma P. Freundt, Anita Schmitt, Niels Weinhold, Elias K. Mai, Carsten Müller-Tidow, Hartmut Goldschmidt, Marc S. Raab, Katharina Kriegsmann, Sandra Sauer
Published 2023-11-01

Investigation of Rare Non-Coding Variants in Familial Multiple Myeloma

by Yasmeen Niazi, Nagarajan Paramasivam, Joanna Blocka, Abhishek Kumar, Stefanie Huhn, Matthias Schlesner, Niels Weinhold, Rolf Sijmons, Mirjam De Jong, Brian Durie, Hartmut Goldschmidt, Kari Hemminki, Asta Försti
Published 2022-12-01

Multiple myeloma risk variant at 7p15.3 creates an IRF4-binding site and interferes with CDCA7L expression

by Ni Li, David C. Johnson, Niels Weinhold, James B. Studd, Giulia Orlando, Fabio Mirabella, Jonathan S. Mitchell, Tobias Meissner, Martin Kaiser, Hartmut Goldschmidt, Kari Hemminki, Gareth J. Morgan, Richard S. Houlston
Published 2016-11-01

P839: GAIN OF CHROMOSOME 1Q LEADS TO HIGH EXPRESSION OF SNORD78 AND ABERRANT RIBOSOME METHYLATION

by Duoduo Zhao, Christian Rohde, Stefanie Göllner, Fengbiao Zhou, Cornelius Pauli, Maximilian Blank, Rafael Zinz, Anna Luise Grab, Alexandra M Poos, Lukas John, Stefanie Huhn, Marc S. Raab, Carsten Müller-Tidow, Niels Weinhold
Published 2023-08-01

Concomitant gain of 1q21 and MYC translocation define a poor prognostic subgroup of hyperdiploid multiple myeloma

by Niels Weinhold, Desiree Kirn, Anja Seckinger, Thomas Hielscher, Martin Granzow, Uta Bertsch, Gerlinde Egerer, Hans Salwender, Igor W. Blau, Katja Weisel, Jens Hillengass, Marc S. Raab, Dirk Hose, Hartmut Goldschmidt, Anna Jauch
Published 2016-03-01

Spatial Distribution of Focal Lesions in Whole-Body MRI and Influence of MRI Protocol on Staging in Patients with Smoldering Multiple Myeloma According to the New SLiM-CRAB-Criteri...

by Markus Wennmann, Thomas Hielscher, Laurent Kintzelé, Bjoern H. Menze, Georg Langs, Maximilian Merz, Sandra Sauer, Hans-Ulrich Kauczor, Heinz-Peter Schlemmer, Stefan Delorme, Hartmut Goldschmidt, Niels Weinhold, Jens Hillengass, Marc-André Weber
Published 2020-09-01

Analyzing Longitudinal wb-MRI Data and Clinical Course in a Cohort of Former Smoldering Multiple Myeloma Patients: Connections between MRI Findings and Clinical Progression Pattern...

by Markus Wennmann, Thomas Hielscher, Laurent Kintzelé, Bjoern H. Menze, Georg Langs, Maximilian Merz, Sandra Sauer, Hans-Ulrich Kauczor, Heinz-Peter Schlemmer, Stefan Delorme, Hartmut Goldschmidt, Niels Weinhold, Jens Hillengass, Marc-André Weber
Published 2021-02-01

Enrichment of B cell receptor signaling and epidermal growth factor receptor pathways in monoclonal gammopathy of undetermined significance: a genome-wide genetic interaction study

by Subhayan Chattopadhyay, Hauke Thomsen, Miguel Inacio da Silva Filho, Niels Weinhold, Per Hoffmann, Markus M. Nöthen, Arendt Marina, Karl-Heinz Jöckel, Börge Schmidt, Sonali Pechlivanis, Christian Langer, Hartmut Goldschmidt, Kari Hemminki, Asta Försti
Published 2018-06-01

Pre-Clinical Assessment of SAR442257, a CD38/CD3xCD28 Trispecific T Cell Engager in Treatment of Relapsed/Refractory Multiple Myeloma

by Anna Luise Grab, Peter S. Kim, Lukas John, Kamlesh Bisht, Hongfang Wang, Anja Baumann, Helgi Van de Velde, Irene Sarkar, Debarati Shome, Philipp Reichert, Calin Manta, Stefanie Gryzik, Rogier M. Reijmers, Niels Weinhold, Marc S. Raab
Published 2024-05-01

Characterization of rare germline variants in familial multiple myeloma

by Calogerina Catalano, Nagarajan Paramasivam, Joanna Blocka, Sara Giangiobbe, Stefanie Huhn, Matthias Schlesner, Niels Weinhold, Rolf Sijmons, Mirjam de Jong, Christian Langer, Klaus-Dieter Preuss, Björn Nilsson, Brian Durie, Hartmut Goldschmidt, Obul Reddy Bandapalli, Kari Hemminki, Asta Försti
Published 2021-02-01

The spatio-temporal evolution of multiple myeloma from baseline to relapse-refractory states

by Leo Rasche, Carolina Schinke, Francesco Maura, Michael A. Bauer, Cody Ashby, Shayu Deshpande, Alexandra M. Poos, Maurizio Zangari, Sharmilan Thanendrarajan, Faith E. Davies, Brian A. Walker, Bart Barlogie, Ola Landgren, Gareth J. Morgan, Frits van Rhee, Niels Weinhold
Published 2022-08-01

Clonal hematopoiesis with <i>DNMT3A</i> and <i>PPM1D</i> mutations impairs regeneration in autologous stem cell transplant recipients

by Patrick Stelmach, Sarah Richter, Sandra Sauer, Margarete A. Fabre, Muxin Gu, Christian Rohde, Maike Janssen, Nora Liebers, Rumyana Proynova, Niels Weinhold, Marc S. Raab, Hartmut Goldschmidt, Birgit Besenbeck, Petra Pavel, Sascha Laier, Andreas Trumpp, Sascha Dietrich, George S. Vassiliou, Carsten Müller-Tidow
Published 2023-06-01

The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression

by Mina Ali, Ram Ajore, Anna-Karin Wihlborg, Abhishek Niroula, Bhairavi Swaminathan, Ellinor Johnsson, Owen W Stephens, Gareth Morgan, Tobias Meissner, Ingemar Turesson, Hartmut Goldschmidt, Ulf-Henrik Mellqvist, Urban Gullberg, Markus Hansson, Kari Hemminki, Hareth Nahi, Anders Waage, Niels Weinhold, Björn Nilsson
Published 2018-04-01

Prevalence of the GFI1-36N SNP in Multiple Myeloma Patients and Its Impact on the Prognosis

by Cyrus Khandanpour, Christine Eisfeld, Subbaiah Chary Nimmagadda, Marc S. Raab, Niels Weinhold, Anja Seckinger, Dirk Hose, Anna Jauch, Asta Försti, Asta Försti, Asta Försti, Kari Hemminki, Kari Hemminki, Thomas Hielscher, Manuela Hummel, Manuela Hummel, Georg Lenz, Hartmut Goldschmidt, Hartmut Goldschmidt, Stefanie Huhn
Published 2021-10-01

Comprehensive genomic analysis of refractory multiple myeloma reveals a complex mutational landscape associated with drug resistance and novel therapeutic vulnerabilities

by Nicola Giesen, Nagarajan Paramasivam, Umut H. Toprak, Daniel Huebschmann, Jing Xu, Sebastian Uhrig, Mehmet Samur, Stella Bähr, Martina Fröhlich, Sadaf S. Mughal, Elias K. Mai, Anna Jauch, Carsten Müller-Tidow, Benedikt Brors, Nikhil Munshi, Hartmut Goldschmidt, Niels Weinhold, Matthias Schlesner, Marc S. Raab
Published 2022-01-01

Chromosome 1q21 abnormalities refine outcome prediction in patients with multiple myeloma - a meta-analysis of 2,596 trial patients

by Niels Weinhold, Hans J. Salwender, David A. Cairns, Marc S. Raab, George Waldron, Igor W. Blau, Uta Bertsch, Thomas Hielscher, Gareth J. Morgan, Anna Jauch, Faith E. Davies, Mathias Hänel, Gordon Cook, Christoph Scheid, Richard Houlston, Hartmut Goldschmidt, Graham Jackson, Martin F. Kaiser
Published 2021-06-01