The Impact of Tumor Heterogeneity on Diagnostics and Novel Therapeutic Strategies in Multiple Myeloma

by Leo Rasche, K. Martin Kortüm, Marc S. Raab, Niels Weinhold
Published 2019-03-01

Novel immunotherapies in multiple myeloma – chances and challenges

by Leo Rasche, Ralph Wäsch, Markus Munder, Hartmut Goldschmidt, Marc S. Raab
Published 2021-07-01

BCMA loss in the epoch of novel immunotherapy for multiple myeloma: from biology to clinical practice

by Xiang Zhou, Leo Rasche, K. Martin Kortüm, Julia Mersi, Hermann Einsele
Published 2022-10-01

Toxicities of Chimeric Antigen Receptor T Cell Therapy in Multiple Myeloma: An Overview of Experience From Clinical Trials, Pathophysiology, and Management Strategies

by Xiang Zhou, Leo Rasche, K. Martin Kortüm, Sophia Danhof, Michael Hudecek, Hermann Einsele
Published 2020-12-01

The natural human IgM antibody PAT-SM6 induces apoptosis in primary human multiple myeloma cells by targeting heat shock protein GRP78.

by Leo Rasche, Johannes Duell, Charlotte Morgner, Manik Chatterjee, Frank Hensel, Andreas Rosenwald, Hermann Einsele, Max S Topp, Stephanie Brändlein
Published 2013-01-01

Expression of programmed death-1 on lymphocytes in myeloma patients is lowered during lenalidomide maintenance

by Sophia Danhof, Martin Schreder, Stefan Knop, Leo Rasche, Susanne Strifler, Claudia Löffler, Tea Gogishvili, Hermann Einsele, Michael Hudecek
Published 2018-03-01

Erdheim-Chester disease with Rosai-Dorfman-like lesions: treatment with methotrexate, anakinra and upadacitinib

by Andreas Rosenwald, Marc Schmalzing, Matthias Fröhlich, Jan Portegys, Anke Heidemeier, Michael Gernert, Sebastian Hueper, Patrick Pascal Strunz, Leo Rasche
Published 2023-01-01

Clinical and Biological Characteristics of Medullary and Extramedullary Plasma Cell Dyscrasias

by Snjezana Janjetovic, Philipp Lohneis, Axel Nogai, Derya Balci, Leo Rasche, Doris Jähne, Carsten Bokemeyer, Georgia Schilling, Igor Wolfgang Blau, Martin Schmidt-Hieber
Published 2021-07-01

GRP78-directed immunotherapy in relapsed or refractory multiple myeloma - results from a phase 1 trial with the monoclonal immunoglobulin M antibody PAT-SM6

by Leo Rasche, Johannes Duell, Inês C. Castro, Valentina Dubljevic, Manik Chatterjee, Stefan Knop, Frank Hensel, Andreas Rosenwald, Hermann Einsele, Max S. Topp, Stephanie Brändlein
Published 2015-03-01

Multiagent therapy with pomalidomide, bortezomib, doxorubicin, dexamethasone, and daratumumab (“Pom‐PAD‐Dara”) in relapsed/refractory multiple myeloma

by Xiang Zhou, Maximilian J. Steinhardt, Denise Grathwohl, Katharina Meckel, Katharina Nickel, Hans‐Benno Leicht, Franziska Krummenast, Hermann Einsele, Leo Rasche, Klaus M. Kortüm
Published 2020-08-01

P836: ANTIBODY-DRUG CONJUGATES AS POTENTIAL CAR-T CELL SPECIFIC OFF-SWITCH IN MULTIPLE MYELOMA

by Anna Bielowski, Teresa Kilian, Sarah Rümpeler Calheiros Vera-Cruz, Zeno Riester, Sabrina Prommersberger, Julia Beckmann, Martin Kortüm, Leo Rasche, Hermann Einsele, Michael Hudecek, Sophia Danhof
Published 2023-08-01

Adverse effects and non-relapse mortality of BCMA directed T cell therapies in multiple myeloma: an FAERS database study

by Zimu Gong, Godsfavour Umoru, Jorge Monge, Nishi Shah, Ghulam Rehman Mohyuddin, Sabarinath Venniyil Radhakrishnan, Rajshekhar Chakraborty, Leo Rasche, Carolina Schinke, Anita D’Souza, Meera Mohan
Published 2024-03-01

Extramedullary disease in multiple myeloma: a systematic literature review

by Joan Bladé, Meral Beksac, Jo Caers, Artur Jurczyszyn, Marie von Lilienfeld-Toal, Philippe Moreau, Leo Rasche, Laura Rosiñol, Saad Z. Usmani, Elena Zamagni, Paul Richardson
Published 2022-03-01

Gene Expression Profiling in Multiple Myeloma: Redefining the Paradigm of Risk-Adapted Treatment

by Claudio Cerchione, Saad Z. Usmani, A. Keith Stewart, Martin Kaiser, Martin Kaiser, Leo Rasche, Martin Kortüm, María-Victoria Mateos, Andrew Spencer, Pieter Sonneveld, Kenneth C. Anderson
Published 2022-02-01

Patient selection for CAR T or BiTE therapy in multiple myeloma: Which treatment for each patient?

by David Kegyes, Catalin Constantinescu, Louise Vrancken, Leo Rasche, Celine Gregoire, Bogdan Tigu, Diana Gulei, Delia Dima, Alina Tanase, Hermann Einsele, Stefan Ciurea, Ciprian Tomuleasa, Jo Caers
Published 2022-06-01

Exploration of Artificial Intelligence Use with ARIES in Multiple Myeloma Research

by Sophia Loda, Jonathan Krebs, Sophia Danhof, Martin Schreder, Antonio G. Solimando, Susanne Strifler, Leo Rasche, Martin Kortüm, Alexander Kerscher, Stefan Knop, Frank Puppe, Hermann Einsele, Max Bittrich
Published 2019-07-01

P814: ANALYSIS OF TP53 ALTERATIONS BY WGS REVEALS BIALLELIC 17P DELETIONS IN MULTIPLE MYELOMA

by Marietta Truger, Stephan Hutter, Wencke Walter, Xiang Zhou, Christine Riedhammer, Manja Meggendorfer, Heiko Müller, Wolfgang Kern, Torsten Haferlach, Hermann Einsele, K Martin Kortum, Claudia Haferlach, Leo Rasche
Published 2023-08-01

Carfilzomib Based Treatment Strategies in the Management of Relapsed/Refractory Multiple Myeloma with Extramedullary Disease

by Xiang Zhou, Patricia Flüchter, Katharina Nickel, Katharina Meckel, Janin Messerschmidt, David Böckle, Sebastian Knorz, Maximilian Johannes Steinhardt, Franziska Krummenast, Sophia Danhof, Hermann Einsele, K. Martin Kortüm, Leo Rasche
Published 2020-04-01

Lymphocyte and neutrophil count combined with intestinal bacteria abundance predict the severity of COVID-19

by Liuying Chen, Zhongwei Yin, Dan Zhou, Xin Li, Cheng Yu, Chang Luo, Yu Jin, Lei Zhang, Jun Song, Leo Rasche, Hermann Einsele, Lei Tu, Xiang Zhou, Tao Bai, Xiaohua Hou
Published 2024-01-01

¹⁸F-FDG and ¹¹C-Methionine PET/CT in Newly Diagnosed Multiple Myeloma Patients: Comparison of Volume-Based PET Biomarkers

by Maria I Morales-Lozano, Oliver Viering, Samuel Samnick, Paula Rodriguez-Otero, Andreas K Buck, Maria Marcos-Jubilar, Leo Rasche, Elena Prieto, K Martin Kortüm, Jesus San-Miguel, Maria J. Garcia-Velloso, Constantin Lapa
Published 2020-04-01