Quantification of plasma cell dynamics using mathematical modelling

by Marcel Mohr, Dirk Hose, Anja Seckinger, Anna Marciniak-Czochra
Published 2018-01-01

GenomicScape: an easy-to-use web tool for gene expression data analysis. Application to investigate the molecular events in the differentiation of B cells into plasma cells.

by Alboukadel Kassambara, Thierry Rème, Michel Jourdan, Thierry Fest, Dirk Hose, Karin Tarte, Bernard Klein
Published 2015-01-01

A tissue-based approach to selection of reference genes for quantitative real-time PCR in a sheep osteoporosis model

by Felix Schulze, Deeksha Malhan, Thaqif El Khassawna, Christian Heiss, Anja Seckinger, Dirk Hose, Angela Rösen-Wolff
Published 2017-12-01

Identification of pluripotent and adult stem cell genes unrelated to cell cycle and associated with poor prognosis in multiple myeloma.

by Alboukadel Kassambara, Dirk Hose, Jérôme Moreaux, Thierry Rème, Jennifer Torrent, Jean François Rossi, Hartmut Goldschmidt, Bernard Klein
Published 2012-01-01

Inhibition of DEPDC1A, a bad prognostic marker in multiple myeloma, delays growth and induces mature plasma cell markers in malignant plasma cells.

by Alboukadel Kassambara, Matthieu Schoenhals, Jérôme Moreaux, Jean-Luc Veyrune, Thierry Rème, Hartmut Goldschmidt, Dirk Hose, Bernard Klein
Published 2013-01-01

Targeting CEACAM5-positive solid tumors using NILK-2401, a novel CEACAM5xCD47 κλ bispecific antibody

by Anja Seckinger, Anja Seckinger, Vanessa Buatois, Valéry Moine, Bruno Daubeuf, Françoise Richard, Laurence Chatel, Alizée Viandier, Nicolas Bosson, Emeline Rousset, Krzysztof Masternak, Susana Salgado-Pires, Claudia Batista, Christelle Mougin, Flora Juan-Bégeot, Yves Poitevin, Dirk Hose, Dirk Hose
Published 2024-04-01

Novel recurrent chromosomal aberrations detected in clonal plasma cells of light chain amyloidosis patients show potential adverse prognostic effect: first results from a genome-wi...

by Martin Granzow, Ute Hegenbart, Katrin Hinderhofer, Dirk Hose, Anja Seckinger, Tilmann Bochtler, Kari Hemminki, Hartmut Goldschmidt, Stefan O. Schönland, Anna Jauch
Published 2017-07-01

Changes in magnetic resonance imaging before and after autologous stem cell transplantation correlate with response and survival in multiple myeloma

by Jens Hillengass, Sofia Ayyaz, Kerstin Kilk, Marc-André Weber, Thomas Hielscher, Rajiv Shah, Dirk Hose, Stefan Delorme, Hartmut Goldschmidt, Kai Neben
Published 2012-11-01

Resemblance-Ranking Peptide Library to Screen for Binders to Antibodies on a Peptidomic Scale

by Felix Jenne, Sergey Biniaminov, Nathalie Biniaminov, Philipp Marquardt, Clemens von Bojničić-Kninski, Roman Popov, Anja Seckinger, Dirk Hose, Alexander Nesterov-Mueller
Published 2022-03-01

TACI expression is associated with a mature bone marrow plasma cell signature and C-MAF overexpression in human myeloma cell lines

by Jérôme Moreaux, Dirk Hose, Michel Jourdan, Thierry Reme, Michael Hundemer, Marion Moos, Nicolas Robert, Philippe Moine, John De Vos, Hartmut Goldschmidt, Bernard Klein
Published 2007-06-01

Genes with a spike expression are clustered in chromosome (sub)bands and spike (sub)bands have a powerful prognostic value in patients with multiple myeloma

by Alboukadel Kassambara, Dirk Hose, Jérôme Moreaux, Brian A. Walker, Alexei Protopopov, Thierry Reme, Franck Pellestor, Véronique Pantesco, Anna Jauch, Gareth Morgan, Hartmut Goldschmidt, Bernard Klein
Published 2012-04-01

A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines

by Jérôme Moreaux, Bernard Klein, Régis Bataille, Géraldine Descamps, Sophie Maïga, Dirk Hose, Hartmut Goldschmidt, Anna Jauch, Thierry Rème, Michel Jourdan, Martine Amiot, Catherine Pellat-Deceunynck
Published 2011-04-01

Pyrroline-5-Carboxylate Reductase 1: a novel target for sensitizing multiple myeloma cells to bortezomib by inhibition of PRAS40-mediated protein synthesis

by Inge Oudaert, Hatice Satilmis, Philip Vlummens, Wouter De Brouwer, Anke Maes, Dirk Hose, Elke De Bruyne, Bart Ghesquière, Karin Vanderkerken, Kim De Veirman, Eline Menu
Published 2022-02-01

Thymosin β4 has tumor suppressive effects and its decreased expression results in poor prognosis and decreased survival in multiple myeloma

by Jo Caers, Dirk Hose, Ine Kuipers, Tomas Jan Bos, Els Van Valckenborgh, Eline Menu, Elke De Bruyne, Hartmut Goldschmidt, Ben Van Camp, Bernard Klein, Karin Vanderkerken
Published 2010-01-01

PRC2 targeting is a therapeutic strategy for EZ score defined high-risk multiple myeloma patients and overcome resistance to IMiDs

by Laurie Herviou, Alboukadel Kassambara, Stéphanie Boireau, Nicolas Robert, Guilhem Requirand, Carsten Müller-Tidow, Laure Vincent, Anja Seckinger, Hartmut Goldschmidt, Guillaume Cartron, Dirk Hose, Giacomo Cavalli, Jerome Moreaux
Published 2018-10-01

CD38 as Immunotherapeutic Target in Light Chain Amyloidosis and Multiple Myeloma—Association With Molecular Entities, Risk, Survival, and Mechanisms of Upfront Resistance

by Anja Seckinger, Jens Hillengass, Martina Emde, Susanne Beck, Christoph Kimmich, Tobias Dittrich, Michael Hundemer, Anna Jauch, Ute Hegenbart, Marc-Steffen Raab, Anthony D. Ho, Stefan Schönland, Dirk Hose
Published 2018-07-01

Combining information regarding chromosomal aberrations t(4;14) and del(17p13) with the International Staging System classification allows stratification of myeloma patients underg...

by Kai Neben, Anna Jauch, Uta Bertsch, Christiane Heiss, Thomas Hielscher, Anja Seckinger, Tina Mors, Nadine Zoe Müller, Jens Hillengass, Marc S. Raab, Anthony D. Ho, Dirk Hose, Hartmut Goldschmidt
Published 2010-07-01

The glycome of normal and malignant plasma cells.

by Thomas M Moehler, Anja Seckinger, Dirk Hose, Mindaugas Andrulis, Jèrôme Moreaux, Thomas Hielscher, Martina Willhauck-Fleckenstein, Anette Merling, Uta Bertsch, Anna Jauch, Hartmut Goldschmidt, Bernard Klein, Reinhard Schwartz-Albiez
Published 2013-01-01

Prospective target assessment and multimodal prediction of survival for personalized and risk-adapted treatment strategies in multiple myeloma in the GMMG-MM5 multicenter trial

by Dirk Hose, Susanne Beck, Hans Salwender, Martina Emde, Uta Bertsch, Christina Kunz, Christoph Scheid, Mathias Hänel, Katja Weisel, Thomas Hielscher, Marc S. Raab, Hartmut Goldschmidt, Anna Jauch, Jérôme Moreaux, Anja Seckinger
Published 2019-06-01

Identification of NOTCH-driven matrisome-associated genes as prognostic indicators of multiple myeloma patient survival

by Daniela Simone Maichl, Julius Arthur Kirner, Susanne Beck, Wen-Hui Cheng, Melanie Krug, Martin Kuric, Carsten Patrick Ade, Thorsten Bischler, Franz Jakob, Dirk Hose, Anja Seckinger, Regina Ebert, Franziska Jundt
Published 2023-09-01