Absence of p55 TNF receptor reduces atherosclerosis, but has no major effect on angiotensin II induced aneurysms in LDL receptor deficient mice.

by Sofia Xanthoulea, Melanie Thelen, Chantal Pöttgens, Marion J J Gijbels, Esther Lutgens, Menno P J de Winther
Published 2009-01-01

Correction: Disruption of the Autophagy-Lysosome Pathway Is Involved in Neuropathology of the Mouse Model of Neuronal Ceroid Lipofuscinosis.

by Melanie Thelen, Markus Damme, Michaela Schweizer, Christian Hagel, Andrew M.S. Wong, Jonathan D. Cooper, Thomas Braulke, Giovanna Galliciotti
Published 2012-01-01

Disruption of the autophagy-lysosome pathway is involved in neuropathology of the nclf mouse model of neuronal ceroid lipofuscinosis.

by Melanie Thelen, Markus Damme, Michaela Schweizer, Christian Hagel, Andrew M S Wong, Jonathan D Cooper, Thomas Braulke, Giovanna Galliciotti
Published 2012-01-01

The lysosomal transporter MFSD1 is essential for liver homeostasis and critically depends on its accessory subunit GLMP

by David Massa López, Melanie Thelen, Felix Stahl, Christian Thiel, Arne Linhorst, Marc Sylvester, Irm Hermanns-Borgmeyer, Renate Lüllmann-Rauch, Winnie Eskild, Paul Saftig, Markus Damme
Published 2019-10-01

Disease-Linked Glutarylation Impairs Function and Interactions of Mitochondrial Proteins and Contributes to Mitochondrial Heterogeneity

by Jessica Schmiesing, Stephan Storch, Ann-Cathrin Dörfler, Michaela Schweizer, Georgia Makrypidi-Fraune, Melanie Thelen, Marc Sylvester, Volkmar Gieselmann, Catherine Meyer-Schwesinger, Friedrich Koch-Nolte, Henning Tidow, Chris Mühlhausen, Abdul Waheed, William S. Sly, Thomas Braulke
Published 2018-09-01

A mouse model for SPG48 reveals a block of autophagic flux upon disruption of adaptor protein complex five

by Mukhran Khundadze, Federico Ribaudo, Adeela Hussain, Jan Rosentreter, Sandor Nietzsche, Melanie Thelen, Dominic Winter, Birgit Hoffmann, Muhammad Awais Afzal, Tanja Hermann, Cecilia de Heus, Eva-Maria Piskor, Christian Kosan, Patricia Franzka, Lisa von Kleist, Tobias Stauber, Judith Klumperman, Markus Damme, Tassula Proikas-Cezanne, Christian A. Hübner
Published 2019-07-01