Common Transcriptional Program of Liver Fibrosis in Mouse Genetic Models and Humans

by Kaja Blagotinšek Cokan, Žiga Urlep, Miha Moškon, Miha Mraz, Xiang Yi Kong, Winnie Eskild, Damjana Rozman, Peter Juvan, Tadeja Režen
Published 2021-01-01

Liver sinusoidal endothelial cells show reduced scavenger function and downregulation of Fc gamma receptor IIb, yet maintain a preserved fenestration in the Glmpgt/gt mouse model o...

by Milton Boaheng Antwi, Gianina Dumitriu, Jaione Simón-Santamaria, Javier Sánchez Romano, Ruomei Li, Bård Smedsrød, Anders Vik, Winnie Eskild, Karen Kristine Sørensen
Published 2023-01-01

Liver sinusoidal endothelial cells show reduced scavenger function and downregulation of Fc gamma receptor IIb, yet maintain a preserved fenestration in the Glmpgt/gt mouse model o...

by Milton Boaheng Antwi, Gianina Dumitriu, Jaione Simón-Santamaria, Javier Sánchez Romano, Ruomei Li, Bård Smedsrød, Anders Vik, Winnie Eskild, Karen Kristine Sørensen
Published 2023-01-01

Lack of the Lysosomal Membrane Protein, GLMP, in Mice Results in Metabolic Dysregulation in Liver.

by Xiang Yi Kong, Eili Tranheim Kase, Anette Herskedal, Camilla Schjalm, Markus Damme, Cecilie Kasi Nesset, G Hege Thoresen, Arild C Rustan, Winnie Eskild
Published 2015-01-01

The lysosomal transporter MFSD1 is essential for liver homeostasis and critically depends on its accessory subunit GLMP

by David Massa López, Melanie Thelen, Felix Stahl, Christian Thiel, Arne Linhorst, Marc Sylvester, Irm Hermanns-Borgmeyer, Renate Lüllmann-Rauch, Winnie Eskild, Paul Saftig, Markus Damme
Published 2019-10-01

Loss of lysosomal membrane protein NCU-G1 in mice results in spontaneous liver fibrosis with accumulation of lipofuscin and iron in Kupffer cells

by Xiang Y. Kong, Cecilie Kasi Nesset, Markus Damme, Else-Marit Løberg, Torben Lübke, Jan Mæhlen, Kristin B. Andersson, Petra I. Lorenzo, Norbert Roos, G. Hege Thoresen, Arild C. Rustan, Eili T. Kase, Winnie Eskild
Published 2014-03-01