Targeting chemotherapy-resistant leukemia by combining DNT cellular therapy with conventional chemotherapy

by Branson Chen, Jong Bok Lee, Hyeonjeong Kang, Mark D. Minden, Li Zhang
Published 2018-04-01

Novel subtypes of NPM1-mutated AML with distinct outcome

by Arvind Singh Mer, Mark D. Minden, Benjamin Haibe-Kains, Aaron D. Schimmer
Published 2021-07-01

Pseudolaric Acid B Targets CD147 to Selectively Kill Acute Myeloid Leukemia Cells

by Sheng Zou, Ekaterina Parfenova, Nikolina Vrdoljak, Mark D. Minden, Paul A. Spagnuolo
Published 2024-06-01

Cyclic AMP‐hydrolyzing phosphodiesterase inhibitors potentiate statin‐induced cancer cell death

by Joseph Longo, Aleksandra A. Pandyra, Paweł Stachura, Mark D. Minden, Aaron D. Schimmer, Linda Z. Penn
Published 2020-10-01

Novel Mango Ginger Bioactive (2,4,6-Trihydroxy-3,5-diprenyldihydrochalcone) Inhibits Mitochondrial Metabolism in Combination with Avocatin B

by Varsha Jayasankar, Nikolina Vrdoljak, Alessia Roma, Nawaz Ahmed, Matthew Tcheng, Mark D. Minden, Paul A. Spagnuolo
Published 2022-01-01

Enhancing Therapeutic Efficacy of Double Negative T Cells against Acute Myeloid Leukemia Using Idelalisib

by Hyeonjeong Kang, Jong Bok Lee, Ismat Khatri, Yoosu Na, Cheryl D’Souza, Andrea Arruda, Mark D. Minden, Li Zhang
Published 2021-10-01

Outcomes and Predictors of Mortality for Patients with Acute Leukemia Admitted to the Intensive Care Unit

by Alan P. Kraguljac, Danielle Croucher, Michael Christian, Narmin Ibrahimova, Vikram Kumar, Gabriella Jacob, Alex Kiss, Mark D. Minden, Sangeeta Mehta
Published 2016-01-01

SubID, a non-median dichotomization tool for heterogeneous populations, reveals the pan-cancer significance of INPP4B and its regulation by EVI1 in AML.

by Irakli Dzneladze, John F Woolley, Carla Rossell, Youqi Han, Ayesha Rashid, Michael Jain, Jüri Reimand, Mark D Minden, Leonardo Salmena
Published 2018-01-01

CD16+NK-92 and anti-CD123 monoclonal antibody prolongs survival in primary human acute myeloid leukemia xenografted mice

by Brent A. Williams, Xing-Hua Wang, Jeffrey V. Leyton, Sonam Maghera, Bishoy Deif, Raymond M. Reilly, Mark D. Minden, Armand Keating
Published 2018-10-01

The Clinical Utility of <i>FLT3</i> Mutation Testing in Acute Leukemia: A Canadian Consensus

by Julie Bergeron, Jose-Mario Capo-Chichi, Hubert Tsui, Etienne Mahe, Philip Berardi, Mark D. Minden, Joseph M. Brandwein, Andre C. Schuh
Published 2023-12-01

Distinct patterns of DNA damage response and apoptosis correlate with Jak/Stat and PI3kinase response profiles in human acute myelogenous leukemia.

by David B Rosen, Santosh Putta, Todd Covey, Ying-Wen Huang, Garry P Nolan, Alessandra Cesano, Mark D Minden, Wendy J Fantl
Published 2010-08-01

TP53 Mutations in AML Patients Are Associated with Dismal Clinical Outcome Irrespective of Frontline Induction Regimen and Allogeneic Hematopoietic Cell Transplantation

by Davidson Zhao, Mojgan Zarif, Qianghua Zhou, José-Mario Capo-Chichi, Andre Schuh, Mark D. Minden, Eshetu G. Atenafu, Rajat Kumar, Hong Chang
Published 2023-06-01

Cell-free DNA topology depends on its subcellular and cellular origins in cancer

by Ethan Z. Malkin, Steven De Michino, Meghan Lambie, Rita Gill, Zhen Zhao, Ariana Rostami, Andrea Arruda, Mark D. Minden, Scott V. Bratman
Published 2022-10-01

Heterogeneity in leukemia cells that escape drug-induced senescence-like state

by David Miller, Kyra Kerkhofs, Farnoosh Abbas-Aghababazadeh, Sahib Singh Madahar, Mark D. Minden, Josée Hébert, Benjamin Haibe-Kains, Mark A. Bayfield, Samuel Benchimol
Published 2023-08-01

Functional characterization of FLT3 receptor signaling deregulation in acute myeloid leukemia by single cell network profiling (SCNP).

by David B Rosen, Mark D Minden, Steven M Kornblau, Aileen Cohen, Urte Gayko, Santosh Putta, John Woronicz, Erik Evensen, Wendy J Fantl, Alessandra Cesano
Published 2010-01-01

Shikonin impairs mitochondrial activity to selectively target leukemia cells

by Alessia Roma, Matthew Tcheng, Nawaz Ahmed, Sarah Walker, Preethi Jayanth, Mark D. Minden, Julie A. Reisz, Angelo D'Alessandro, Jakub Rohlena, Paul A. Spagnuolo
Published 2022-08-01

Increased pressure alters plasma membrane dynamics and renders acute myeloid leukemia cells resistant to daunorubicin

by Victor Sanjit Nirmalanandhan, Rose Hurren, William D. Cameron, Marcela Gronda, Aisha Shamas-Din, Lidan You, Mark D. Minden, Jonathan V. Rocheleau, Aaron D Schimmer
Published 2015-10-01

Preclinical validation: LV/IL-12 transduction of patient leukemia cells for immunotherapy of AML

by Ju Huang, Yuanfeng Liu, Bryan C Au, Dwayne L Barber, Andrea Arruda, Axel Schambach, Michael Rothe, Mark D Minden, Christopher J Paige, Jeffrey A Medin
Published 2016-01-01

Quality of life and socioeconomic indicators associated with survival of myeloid leukemias in Canada

by Sonya Cressman, Donna E. Hogge, Mark D. Minden, Stephen Couban, Aly Karsan, Raewyn Broady, Emily McPherson, Khalif Halani, Jing Yi Weng, Stuart J. Peacock
Published 2020-07-01

PRMT5 regulates ATF4 transcript splicing and oxidative stress response

by Magdalena M. Szewczyk, Genna M. Luciani, Victoria Vu, Alex Murison, David Dilworth, Samir H. Barghout, Mathieu Lupien, Cheryl H. Arrowsmith, Mark D. Minden, Dalia Barsyte-Lovejoy
Published 2022-05-01