Cell by cell immuno- and cancer marker profiling of non-small cell lung cancer tissue: Checkpoint marker expression on CD103+, CD4+ T-cells predicts circulating tumor cells

by Xiaoyang Wang, Maria Jaimes, Huimin Gu, Keith Shults, Santosh Putta, Vishal Sharma, Will Chow, Priya Gogoi, Kalyan Handique, Bruce K Patterson
Published 2021-01-01

Distinct patterns of DNA damage response and apoptosis correlate with Jak/Stat and PI3kinase response profiles in human acute myelogenous leukemia.

by David B Rosen, Santosh Putta, Todd Covey, Ying-Wen Huang, Garry P Nolan, Alessandra Cesano, Mark D Minden, Wendy J Fantl
Published 2010-08-01

Functional characterization of FLT3 receptor signaling deregulation in acute myeloid leukemia by single cell network profiling (SCNP).

by David B Rosen, Mark D Minden, Steven M Kornblau, Aileen Cohen, Urte Gayko, Santosh Putta, John Woronicz, Erik Evensen, Wendy J Fantl, Alessandra Cesano
Published 2010-01-01

Functional pathway analysis using SCNP of FLT3 receptor pathway deregulation in AML provides prognostic information independent from mutational status.

by Alessandra Cesano, Santosh Putta, David B Rosen, Aileen C Cohen, Urte Gayko, Kavita Mathi, John Woronicz, Rachael E Hawtin, Larry Cripe, Zhuoxin Sun, Martin S Tallman, Elisabeth Paietta
Published 2013-01-01

AKT signaling as a novel factor associated with in vitro resistance of human AML to gemtuzumab ozogamicin.

by David B Rosen, Kimberly H Harrington, James A Cordeiro, Ling Y Leung, Santosh Putta, Norman Lacayo, George S Laszlo, Chelsea J Gudgeon, Donna E Hogge, Rachael E Hawtin, Alessandra Cesano, Roland B Walter
Published 2013-01-01

Integration of B-cell receptor-induced ERK1/2 phosphorylation and mutations of SF3B1 gene refines prognosis in treatment-naïve chronic lymphocytic leukemia

by Chiara Cavallini, Carlo Visco, Santosh Putta, Davide Rossi, Elda Mimiola, Norman Purvis, Ornella Lovato, Omar Perbellini, Erika Falisi, Monica Facco, Livio Trentin, Maria G. Romanelli, Gianpietro Semenzato, Achille Ambrosetti, Gianluca Gaidano, Giovanni Pizzolo, Alessandra Cesano, Maria T. Scupoli
Published 2017-04-01

B-cell receptor signaling activity identifies patients with mantle cell lymphoma at higher risk of progression

by Simona Gambino, Francesca Maria Quaglia, Marilisa Galasso, Chiara Cavallini, Roberto Chignola, Ornella Lovato, Luca Giacobazzi, Simone Caligola, Annalisa Adamo, Santosh Putta, Antonino Aparo, Isacco Ferrarini, Stefano Ugel, Rosalba Giugno, Massimo Donadelli, Ilaria Dando, Mauro Krampera, Carlo Visco, Maria Teresa Scupoli
Published 2024-03-01

Cell signaling-based classifier predicts response to induction therapy in elderly patients with acute myeloid leukemia.

by Alessandra Cesano, Cheryl L Willman, Kenneth J Kopecky, Urte Gayko, Santosh Putta, Brent Louie, Matt Westfall, Norman Purvis, David C Spellmeyer, Carol Marimpietri, Aileen C Cohen, James Hackett, Jing Shi, Michael G Walker, Zhuoxin Sun, Elisabeth Paietta, Martin S Tallman, Larry D Cripe, Susan Atwater, Frederick R Appelbaum, Jerald P Radich
Published 2015-01-01