Nonsense Suppression as an Approach to Treat Lysosomal Storage Diseases

by Kim M. Keeling
Published 2016-10-01

Finding sense in the context

by Kim M Keeling, David M Bedwell
Published 2020-03-01

RNA binding proteins PTBP1 and HNRNPL regulate CFTR mRNA decay

by Amna Siddiqui, Arpit Saxena, Joshua Echols, Viktoria Havasi, Lianwu Fu, Kim M. Keeling
Published 2023-11-01

A regulated NMD mouse model supports NMD inhibition as a viable therapeutic option to treat genetic diseases

by Josh Echols, Amna Siddiqui, Yanying Dai, Viktoria Havasi, Richard Sun, Aneta Kaczmarczyk, Kim M. Keeling
Published 2020-08-01

Extended stop codon context predicts nonsense codon readthrough efficiency in human cells

by Kotchaphorn Mangkalaphiban, Lianwu Fu, Ming Du, Kari Thrasher, Kim M. Keeling, David M. Bedwell, Allan Jacobson
Published 2024-03-01

Attenuation of nonsense-mediated mRNA decay enhances in vivo nonsense suppression.

by Kim M Keeling, Dan Wang, Yanying Dai, Srinivasan Murugesan, Balachandra Chenna, Jeremy Clark, Valery Belakhov, Jeyakumar Kandasamy, Sadanandan E Velu, Timor Baasov, David M Bedwell
Published 2013-01-01

Mutation-Directed Therapeutics for Neurofibromatosis Type I

by Andre Leier, David M. Bedwell, Ann T. Chen, George Dickson, Kim M. Keeling, Robert A. Kesterson, Bruce R. Korf, Tatiana T. Marquez Lago, Ulrich F. Müller, Linda Popplewell, Jiangbing Zhou, Deeann Wallis
Published 2020-06-01

Triamterene Functions as an Effective Nonsense Suppression Agent for MPS I-H (Hurler Syndrome)

by Amna Siddiqui, Halil Dundar, Jyoti Sharma, Aneta Kaczmarczyk, Josh Echols, Yanying Dai, Chuanxi Richard Sun, Ming Du, Zhong Liu, Rui Zhao, Tim Wood, Shalisa Sanders, Lynn Rasmussen, James Robert Bostwick, Corinne Augelli-Szafran, Mark Suto, Steven M. Rowe, David M. Bedwell, Kim M. Keeling
Published 2023-02-01

A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion

by Jyoti Sharma, Ming Du, Eric Wong, Venkateshwar Mutyam, Yao Li, Jianguo Chen, Jamie Wangen, Kari Thrasher, Lianwu Fu, Ning Peng, Liping Tang, Kaimao Liu, Bini Mathew, Robert J. Bostwick, Corinne E. Augelli-Szafran, Hermann Bihler, Feng Liang, Jerome Mahiou, Josef Saltz, Andras Rab, Jeong Hong, Eric J. Sorscher, Eric M. Mendenhall, Candice J. Coppola, Kim M. Keeling, Rachel Green, Martin Mense, Mark J. Suto, Steven M. Rowe, David M. Bedwell
Published 2021-07-01