Cyanobacterial Metabolite Calothrixins: Recent Advances in Synthesis and Biological Evaluation

by Su Xu, Bhavitavya Nijampatnam, Shilpa Dutta, Sadanandan E. Velu
Published 2016-01-01

Antibacterial and Antibiofilm Activities of Makaluvamine Analogs

by Bhavitavya Nijampatnam, Dwayaja H. Nadkarni, Hui Wu, Sadanandan E. Velu
Published 2014-09-01

Tetracyclic homoisoflavanoid (+)-brazilin: a natural product inhibits c-di-AMP-producing enzyme and Streptococcus mutans biofilms

by Edwin M. Rojas, Hua Zhang, Sadanandan E. Velu, Hui Wu
Published 2024-05-01

Nonsense-mediated decay controls the reactivation of the oncogenic herpesviruses EBV and KSHV.

by Michiel van Gent, Adrian Reich, Sadanandan E Velu, Michaela U Gack
Published 2021-02-01

Inhibition of Streptococcus mutans Biofilms by the Natural Stilbene Piceatannol Through the Inhibition of Glucosyltransferases

by Bhavitavya Nijampatnam, Hua Zhang, Xia Cai, Suzanne M. Michalek, Hui Wu, Sadanandan E. Velu
Published 2018-07-01

A Novel Marine Natural Product Derived Pyrroloiminoquinone with Potent Activity against Skin Cancer Cells

by Jaden Cowan, Mohammad Shadab, Dwayaja H. Nadkarni, Kailash KC, Sadanandan E. Velu, Nabiha Yusuf
Published 2019-07-01

Structure-Based Discovery of Small Molecule Inhibitors of Cariogenic Virulence

by Qiong Zhang, Bhavitavya Nijampatnam, Zhang Hua, Thao Nguyen, Jing Zou, Xia Cai, Suzanne M. Michalek, Sadanandan E. Velu, Hui Wu
Published 2017-07-01

Pharmacological and nutritional targeting of voltage-gated sodium channels in the treatment of cancers

by Osbaldo Lopez-Charcas, Piyasuda Pukkanasut, Sadanandan E. Velu, William J. Brackenbury, Tim G. Hales, Pierre Besson, Juan Carlos Gomora, Sébastien Roger
Published 2021-04-01

Synthetic Makaluvamine Analogs Decrease c-Kit Expression and Are Cytotoxic to Neuroendocrine Tumor Cells

by Zviadi Aburjania, Jason D. Whitt, Samuel Jang, Dwayaja H. Nadkarni, Herbert Chen, J. Bart Rose, Sadanandan E. Velu, Renata Jaskula-Sztul
Published 2020-10-01

Preclinical Evaluation of Anticancer Efficacy and Pharmacological Properties of FBA-TPQ, a Novel Synthetic Makaluvamine Analog

by Sadanandan E. Velu, Ming-Hai Wang, Ruiwen Zhang, Wei Wang, Dwayaja H. Nadkarni, Sukesh Voruganti, Srinivasan Murugesan, Xu Zhang, Xiangrong Zhang, Hongxia Xu
Published 2012-05-01

Attenuation of nonsense-mediated mRNA decay enhances in vivo nonsense suppression.

by Kim M Keeling, Dan Wang, Yanying Dai, Srinivasan Murugesan, Balachandra Chenna, Jeremy Clark, Valery Belakhov, Jeyakumar Kandasamy, Sadanandan E Velu, Timor Baasov, David M Bedwell
Published 2013-01-01

Preclinical Pharmacology of BA-TPQ, a Novel Synthetic Iminoquinone Anticancer Agent

by Ruiwen Zhang, Wei Wang, Sadanandan E. Velu, Xinyi Yang, Charnell I. Sommers, Elizabeth R. Rayburn, Xu Zhang, Evrim Gurpinar, Hongxia Xu, Xiangrong Zhang, Scharri J. Ezell, Haibo Li
Published 2010-07-01

Experimental therapy of ovarian cancer with synthetic makaluvamine analog: in vitro and in vivo anticancer activity and molecular mechanisms of action.

by Tao Chen, Yi Xu, He Guo, Yanling Liu, Pingting Hu, Xinying Yang, Xiaoguang Li, Shichao Ge, Sadanandan E Velu, Dwayaja H Nadkarni, Wei Wang, Ruiwen Zhang, Hui Wang
Published 2011-01-01

Voltage-Gated Sodium Channel Na_V1.7 Inhibitors with Potent Anticancer Activities in Medullary Thyroid Cancer Cells

by Piyasuda Pukkanasut, Jason Whitt, Rachael Guenter, Shannon E. Lynch, Carlos Gallegos, Margarita Jacaranda Rosendo-Pineda, Juan Carlos Gomora, Herbert Chen, Diana Lin, Anna Sorace, Renata Jaskula-Sztul, Sadanandan E. Velu
Published 2023-05-01

A novel class of mitochondria-targeted soft electrophiles modifies mitochondrial proteins and inhibits mitochondrial metabolism in breast cancer cells through redox mechanisms.

by Praveen K Vayalil, Joo-Yeun Oh, Fen Zhou, Anne R Diers, M Ryan Smith, Hafez Golzarian, Patsy G Oliver, Robin A J Smith, Michael P Murphy, Sadanandan E Velu, Aimee Landar
Published 2015-01-01

Voltage-Gated Sodium Channel Na_V1.5 Controls NHE−1−Dependent Invasive Properties in Colon Cancer Cells

by Osbaldo Lopez-Charcas, Lucile Poisson, Oumnia Benouna, Roxane Lemoine, Stéphanie Chadet, Adrien Pétereau, Widad Lahlou, Serge Guyétant, Mehdi Ouaissi, Piyasuda Pukkanasut, Shilpa Dutta, Sadanandan E. Velu, Pierre Besson, Driffa Moussata, Sébastien Roger
Published 2022-12-01

Mitochondrial thiol modification by a targeted electrophile inhibits metabolism in breast adenocarcinoma cells by inhibiting enzyme activity and protein levels

by M. Ryan Smith, Praveen K. Vayalil, Fen Zhou, Gloria A. Benavides, Reena R. Beggs, Hafez Golzarian, Bhavitavya Nijampatnam, Patsy G. Oliver, Robin A.J. Smith, Michael P. Murphy, Sadanandan E. Velu, Aimee Landar
Published 2016-08-01