Targeted Gene Insertion for Functional CFTR Restoration in Airway Epithelium

by Cristina Barillà, Shingo Suzuki, Andras Rab, Eric J. Sorscher, Brian R. Davis
Published 2022-03-01

Robust Stimulation of W1282X-CFTR Channel Activity by a Combination of Allosteric Modulators.

by Wei Wang, Jeong S Hong, Andras Rab, Eric J Sorscher, Kevin L Kirk
Published 2016-01-01

Reduced bone length, growth plate thickness, bone content, and IGF-I as a model for poor growth in the CFTR-deficient rat.

by Michael S Stalvey, Viktoria Havasi, Katherine L Tuggle, Dezhi Wang, Susan Birket, Steve M Rowe, Eric J Sorscher
Published 2017-01-01

Myofibroblast differentiation and enhanced TGF-B signaling in cystic fibrosis lung disease.

by William T Harris, David R Kelly, Yong Zhou, Dezhi Wang, Mark MacEwen, James S Hagood, J P Clancy, Namasivayam Ambalavanan, Eric J Sorscher
Published 2013-01-01

Correction: Myofibroblast Differentiation and Enhanced Tgf-B Signaling in Cystic Fibrosis Lung Disease.

by William T. Harris, David R. Kelly, Yong Zhou, Dezhi Wang, Mark MacEwen, James S. Hagood, J. P. Clancy, Namasivayam Ambalavanan, Eric J. Sorscher
Published 2013-01-01

Resveratrol enhances airway surface liquid depth in sinonasal epithelium by increasing cystic fibrosis transmembrane conductance regulator open probability.

by Shaoyan Zhang, Angela C Blount, Carmel M McNicholas, Daniel F Skinner, Michael Chestnut, John C Kappes, Eric J Sorscher, Bradford A Woodworth
Published 2013-01-01

Longevity and plasticity of CFTR provide an argument for noncanonical SNP organization in hominid DNA.

by Aubrey E Hill, Zackery E Plyler, Hemant Tiwari, Amit Patki, Joel P Tully, Christopher W McAtee, Leah A Moseley, Eric J Sorscher
Published 2014-01-01

Correction: Resveratrol Enhances Airway Surface Liquid Depth in Sinonasal Epithelium by Increasing Cystic Fibrosis Transmembrane Conductance Regulator Open Probability.

by Shaoyan Zhang, Angela C. Blount, Carmel M. McNicholas, Daniel F. Skinner, Michael Chestnut, John C. Kappes, Eric J. Sorscher, Bradford A. Woodworth
Published 2014-01-01

Relationships between genomic dissipation and de novo SNP evolution.

by Zackery E Plyler, Christopher W McAtee, Aubrey E Hill, Michael R Crowley, Janice M Tindall, Samuel R Tindall, Disha Joshi, Eric J Sorscher
Published 2024-01-01

Sinupret activates CFTR and TMEM16A-dependent transepithelial chloride transport and improves indicators of mucociliary clearance.

by Shaoyan Zhang, Daniel Skinner, Stephen Bradley Hicks, Mark O Bevensee, Eric J Sorscher, Ahmed Lazrak, Sadis Matalon, Carmel M McNicholas, Bradford A Woodworth
Published 2014-01-01

A medium composition containing normal resting glucose that supports differentiation of primary human airway cells

by Rachel Morgan, Candela Manfredi, Kristen F. Easley, Lionel D. Watkins, William R. Hunt, Steven L. Goudy, Eric J. Sorscher, Michael Koval, Samuel A. Molina
Published 2022-01-01

Translation velocity determines the efficacy of engineered suppressor tRNAs on pathogenic nonsense mutations

by Nikhil Bharti, Leonardo Santos, Marcos Davyt, Stine Behrmann, Marie Eichholtz, Alejandro Jimenez-Sanchez, Jeong S. Hong, Andras Rab, Eric J. Sorscher, Suki Albers, Zoya Ignatova
Published 2024-04-01

Assessing cell-specific effects of genetic variations using tRNA microarrays

by Christine Polte, Daniel Wedemeyer, Kathryn E. Oliver, Johannes Wagner, Marcel J. C. Bijvelds, John Mahoney, Hugo R. de Jonge, Eric J. Sorscher, Zoya Ignatova
Published 2019-07-01

Evaluating antitumor activity of Escherichia coli purine nucleoside phosphorylase against head and neck patient‐derived xenografts

by Regina Rab, Annette Ehrhardt, Bhagelu R. Achyut, Disha Joshi, Melissa Gilbert‐Ross, Chunzi Huang, Katharine Floyd, Anton V. Borovjagin, William B. Parker, Eric J. Sorscher, Jeong S. Hong
Published 2023-02-01

Ribosomal Stalk Protein Silencing Partially Corrects the ΔF508-CFTR Functional Expression Defect.

by Guido Veit, Kathryn Oliver, Pirjo M Apaja, Doranda Perdomo, Aurélien Bidaud-Meynard, Sheng-Ting Lin, Jingyu Guo, Mert Icyuz, Eric J Sorscher, John L Hartman, Gergely L Lukacs
Published 2016-05-01

LPS decreases CFTR open probability and mucociliary transport through generation of reactive oxygen species

by Do Yeon Cho, Shaoyan Zhang, Ahmed Lazrak, Daniel Skinner, Harrison M. Thompson, Jessica Grayson, Purushotham Guroji, Saurabh Aggarwal, Zsuzsanna Bebok, Steven M. Rowe, Sadis Matalon, Eric J. Sorscher, Bradford A. Woodworth
Published 2021-07-01

A pharmacologic approach to acquired cystic fibrosis transmembrane conductance regulator dysfunction in smoking related lung disease.

by Peter A Sloane, Suresh Shastry, Andrew Wilhelm, Clifford Courville, Li Ping Tang, Kyle Backer, Elina Levin, S Vamsee Raju, Yao Li, Marina Mazur, Suzanne Byan-Parker, William Grizzle, Eric J Sorscher, Mark T Dransfield, Steven M Rowe
Published 2012-01-01

Method for quantitative study of airway functional microanatomy using micro-optical coherence tomography.

by Linbo Liu, Kengyeh K Chu, Grace H Houser, Bradford J Diephuis, Yao Li, Eric J Wilsterman, Suresh Shastry, Gregory Dierksen, Susan E Birket, Marina Mazur, Suzanne Byan-Parker, William E Grizzle, Eric J Sorscher, Steven M Rowe, Guillermo J Tearney
Published 2013-01-01

Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule The...

by W Joon Chung, Jennifer L Goeckeler-Fried, Viktoria Havasi, Annette Chiang, Steven M Rowe, Zackery E Plyler, Jeong S Hong, Marina Mazur, Gary A Piazza, Adam B Keeton, E Lucile White, Lynn Rasmussen, Allan M Weissman, R Aldrin Denny, Jeffrey L Brodsky, Eric J Sorscher
Published 2016-01-01

Characterization of defects in ion transport and tissue development in cystic fibrosis transmembrane conductance regulator (CFTR)-knockout rats.

by Katherine L Tuggle, Susan E Birket, Xiaoxia Cui, Jeong Hong, Joe Warren, Lara Reid, Andre Chambers, Diana Ji, Kevin Gamber, Kengyeh K Chu, Guillermo Tearney, Li Ping Tang, James A Fortenberry, Ming Du, Joan M Cadillac, David M Bedwell, Steven M Rowe, Eric J Sorscher, Michelle V Fanucchi
Published 2014-01-01