Transcriptional repression and cell death induced by nuclear aggregates of non-polyglutamine protein

by Lianwu Fu, Ya-sheng Gao, Elizabeth Sztul
Published 2005-12-01

Human cytomegalovirus UL97 kinase prevents the deposition of mutant protein aggregates in cellular models of Huntington's disease and Ataxia

by Cristy Tower, Lianwu Fu, Rachel Gill, Mark Prichard, Mathieu Lesort, Elizabeth Sztul
Published 2011-01-01

RNA binding proteins PTBP1 and HNRNPL regulate CFTR mRNA decay

by Amna Siddiqui, Arpit Saxena, Joshua Echols, Viktoria Havasi, Lianwu Fu, Kim M. Keeling
Published 2023-11-01

Extended stop codon context predicts nonsense codon readthrough efficiency in human cells

by Kotchaphorn Mangkalaphiban, Lianwu Fu, Ming Du, Kari Thrasher, Kim M. Keeling, David M. Bedwell, Allan Jacobson
Published 2024-03-01

ΔF508 CFTR surface stability is regulated by DAB2 and CHIP-mediated ubiquitination in post-endocytic compartments.

by Lianwu Fu, Andras Rab, Li ping Tang, Zsuzsa Bebok, Steven M Rowe, Rafal Bartoszewski, James F Collawn
Published 2015-01-01

Chymase uptake by cardiomyocytes results in myosin degradation in cardiac volume overload

by Pamela C. Powell, Chih-Chang Wei, Lianwu Fu, Betty Pat, Wayne E. Bradley, James F. Collawn, Louis J. Dell'Italia
Published 2019-04-01

Prime editing-mediated correction of the CFTR W1282X mutation in iPSCs and derived airway epithelial cells

by Chao Li, Zhong Liu, Justin Anderson, Zhongyu Liu, Liping Tang, Yao Li, Ning Peng, Jianguo Chen, Xueming Liu, Lianwu Fu, Tim M. Townes, Steven M. Rowe, David M. Bedwell, Jennifer Guimbellot, Rui Zhao
Published 2023-01-01

Prime editing-mediated correction of the CFTR W1282X mutation in iPSCs and derived airway epithelial cells.

by Chao Li, Zhong Liu, Justin Anderson, Zhongyu Liu, Liping Tang, Yao Li, Ning Peng, Jianguo Chen, Xueming Liu, Lianwu Fu, Tim M Townes, Steven M Rowe, David M Bedwell, Jennifer Guimbellot, Rui Zhao
Published 2023-01-01

Mucociliary transport deficiency and disease progression in Syrian hamsters with SARS-CoV-2 infection

by Qian Li, Kadambari Vijaykumar, Scott E. Phillips, Shah S. Hussain, Nha V. Huynh, Courtney M. Fernandez-Petty, Jacelyn E. Peabody Lever, Jeremy B. Foote, Janna Ren, Javier Campos-Gómez, Farah Abou Daya, Nathaniel W. Hubbs, Harrison Kim, Ezinwanne Onuoha, Evan R. Boitet, Lianwu Fu, Hui Min Leung, Linhui Yu, Thomas W. Detchemendy, Levi T. Schaefers, Jennifer L. Tipper, Lloyd J. Edwards, Sixto M. Leal Jr., Kevin S. Harrod, Guillermo J. Tearney, Steven M. Rowe
Published 2023-01-01

A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion

by Jyoti Sharma, Ming Du, Eric Wong, Venkateshwar Mutyam, Yao Li, Jianguo Chen, Jamie Wangen, Kari Thrasher, Lianwu Fu, Ning Peng, Liping Tang, Kaimao Liu, Bini Mathew, Robert J. Bostwick, Corinne E. Augelli-Szafran, Hermann Bihler, Feng Liang, Jerome Mahiou, Josef Saltz, Andras Rab, Jeong Hong, Eric J. Sorscher, Eric M. Mendenhall, Candice J. Coppola, Kim M. Keeling, Rachel Green, Martin Mense, Mark J. Suto, Steven M. Rowe, David M. Bedwell
Published 2021-07-01