Complementarity of ultrasound and fluorescence imaging in an orthotopic mouse model of pancreatic cancer

by Cao Hop, Kono Yuko, Kaushal Sharmeela, Snyder Cynthia S, Hoffman Robert M, Bouvet Michael
Published 2009-04-01

Adenoviral targeting of malignant melanoma for fluorescence-guided surgery prevents recurrence in orthotopic nude-mouse models.

by Yano, Shuya, Takehara, Kiyoto, Kishimoto, Hiroyuki, Urata, Yasuo, Kagawa, Shunsuke, Bouvet, Michael, Fujiwara, Toshiyoshi, Hoffman, Robert M
Published 2016

Osimertinib Regresses an EGFR-Mutant Cisplatinum- Resistant Lung Adenocarcinoma Growing in the Brain in Nude Mice.

by Higuchi, Takashi, Oshiro, Hiromichi, Zhang, Zhiying, Miyake, Kentaro, Sugisawa, Norihiko, Katsuya, Yuki, Yamamoto, Norio, Hayashi, Katsuhiro, Kimura, Hiroaki, Miwa, Shinji, Igarashi, Kentaro, Zhao, Ming, Bouvet, Michael, Singh, Shree Ram, Tsuchiya, Hiroyuki, Hoffman, Robert M
Published 2019

Osimertinib regressed an EGFR-mutant lung-adenocarcinoma bone-metastasis mouse model and increased long-term survival.

by Higuchi, Takashi, Sugisawa, Norihiko, Park, Jun Ho, Sun, Yu, Zhu, Guangwei, Yamamoto, Norio, Hayashi, Katsuhiro, Kimura, Hiroaki, Miwa, Shinji, Igarashi, Kentaro, Bouvet, Michael, Singh, Shree Ram, Tsuchiya, Hiroyuki, Hoffman, Robert M
Published 2020

The Combination of Olaratumab with Doxorubicin and Cisplatinum Regresses a Chemotherapy-Resistant Osteosarcoma in a Patient-Derived Orthotopic Xenograft Mouse Model.

by Higuchi, Takashi, Sugisawa, Norihiko, Miyake, Kentaro, Oshiro, Hiromichi, Yamamoto, Norio, Hayashi, Katsuhiro, Kimura, Hiroaki, Miwa, Shinji, Igarashi, Kentaro, Bouvet, Michael, Singh, Shree Ram, Tsuchiya, Hiroyuki, Hoffman, Robert M
Published 2019

Precise navigation surgery of tumours in the lung in mouse models enabled by in situ fluorescence labelling with a killer-reporter adenovirus.

by Yano, Shuya, Zhang, Yong, Miwa, Shinji, Kishimoto, Hiroyuki, Urata, Yasuo, Bouvet, Michael, Kagawa, Shunsuke, Fujiwara, Toshiyoshi, Hoffman, Robert M
Published 2015

Adjuvant treatment with tumor-targeting Salmonella typhimurium A1-R reduces recurrence and increases survival after liver metastasis resection in an orthotopic nude mouse model.

by Murakami, Takashi, Hiroshima, Yukihiko, Zhao, Ming, Zhang, Yong, Chishima, Takashi, Tanaka, Kuniya, Bouvet, Michael, Endo, Itaru, Hoffman, Robert M
Published 2015

Therapeutic efficacy of tumor-targeting Salmonella typhimurium A1-R on human colorectal cancer liver metastasis in orthotopic nude-mouse models.

by Murakami, Takashi, Hiroshima, Yukihiko, Zhao, Ming, Zhang, Yong, Chishima, Takashi, Tanaka, Kuniya, Bouvet, Michael, Endo, Itaru, Hoffman, Robert M
Published 2015

Fluorescence-guided surgery of a highly-metastatic variant of human triple-negative breast cancer targeted with a cancer-specific GFP adenovirus prevents recurrence.

by Yano, Shuya, Takehara, Kiyoto, Miwa, Shinji, Kishimoto, Hiroyuki, Tazawa, Hiroshi, Urata, Yasuo, Kagawa, Shunsuke, Bouvet, Michael, Fujiwara, Toshiyoshi, Hoffman, Robert M
Published 2016

Two-photon imaging of cancer cell extravasation in live mice

by Digman, Michelle A, Aguilar, Jose S, Gratton, Enrico, Suetsugu, Atsushi, Hoffman, Robert M
Published 2011

Patient-derived mouse models of cancer need to be orthotopic in order to evaluate targeted anti-metastatic therapy.

by Hiroshima, Yukihiko, Maawy, Ali, Zhang, Yong, Zhang, Nan, Murakami, Takashi, Chishima, Takashi, Tanaka, Kuniya, Ichikawa, Yasushi, Bouvet, Michael, Endo, Itaru, Hoffman, Robert M
Published 2016

Disintegrin targeting of an αvβ3 integrin-over-expressing high-metastatic human osteosarcoma with echistatin inhibits cell proliferation, migration, invasion and adhesion in vitro....

by Tome, Yasunori, Kimura, Hiroaki, Kiyuna, Tasuku, Sugimoto, Naotoshi, Tsuchiya, Hiroyuki, Kanaya, Fuminori, Bouvet, Michael, Hoffman, Robert M
Published 2016

A novel patient-derived orthotopic xenograft (PDOX) mouse model of highly-aggressive liver metastasis for identification of candidate effective drug-combinations.

by Zhang, Zhiying, Hu, Kaiwen, Miyake, Kentaro, Kiyuna, Tasuku, Oshiro, Hiromichi, Wangsiricharoen, Sintawat, Kawaguchi, Kei, Higuchi, Takashi, Razmjooei, Sahar, Miyake, Masuyo, Chawla, Sant P, Singh, Shree Ram, Hoffman, Robert M
Published 2020

Histone H3 lysine-trimethylation markers are decreased by recombinant methioninase and increased by methotrexate at concentrations which inhibit methionine-addicted osteosarcoma ce...

by Aoki, Yusuke, Tome, Yasunori, Han, Qinghong, Yamamoto, Jun, Hamada, Kazuyuki, Masaki, Noriyuki, Bouvet, Michael, Nishida, Kotaro, Hoffman, Robert M
Published 2021

The disintegrin echistatin in combination with doxorubicin targets high-metastatic human osteosarcoma overexpressing ανβ3 integrin in chick embryo and nude mouse models.

by Tome, Yasunori, Kimura, Hiroaki, Sugimoto, Naotoshi, Tsuchiya, Hiroyuki, Kanaya, Fuminori, Bouvet, Michael, Hoffman, Robert M
Published 2016

A novel anionic-phosphate-platinum complex effectively targets an undifferentiated pleomorphic sarcoma better than cisplatinum and doxorubicin in a patient-derived orthotopic xenog...

by Igarashi, Kentaro, Kawaguchi, Kei, Murakami, Takashi, Kiyuna, Tasuku, Miyake, Kentaro, Yamamoto, Norio, Hayashi, Katsuhiro, Kimura, Hiroaki, Nelson, Scott D, Dry, Sarah M, Li, Yunfeng, Singh, Arun S, Miwa, Shinji, Odani, Akira, Eilber, Fritz C, Tsuchiya, Hiroyuki, Hoffman, Robert M
Published 2017

Real-time imaging of 3-dimensional cancer cell movement in tissues

by Digman, Michelle, Aguilar, Jose A, Gratton, Enrico, Suetsugu, Atsushi, Hoffman, Robert M
Published 2011

Imaging of methioninase-induced S/G(2)-phase-trapping for subsequent effective chemotherapy

by Yano, Shuya, Tome, Yasunori, Digman, Michelle, Momiyamal, Masashi, Suetsugu, Atsushi, Gratton, Enrico, Hoffman, Robert M
Published 2013

Efficacy of tumor-targeting Salmonella typhimurium A1-R in combination with anti-angiogenesis therapy on a pancreatic cancer patient-derived orthotopic xenograft (PDOX) and cell li...

by Hiroshima, Yukihiko, Zhang, Yong, Murakami, Takashi, Maawy, Ali, Miwa, Shinji, Yamamoto, Mako, Yano, Shuya, Sato, Sho, Momiyama, Masashi, Mori, Ryutaro, Matsuyama, Ryusei, Chishima, Takashi, Tanaka, Kuniya, Ichikawa, Yasushi, Bouvet, Michael, Endo, Itaru, Zhao, Ming, Hoffman, Robert M
Published 2014

Temozolomide and Pazopanib Combined with FOLFOX Regressed a Primary Colorectal Cancer in a Patient-derived Orthotopic Xenograft Mouse Model.

by Zhu, Guangwei, Zhao, Ming, Han, Qinghong, Tan, Yuying, Sun, Yu, Bouvet, Michael, Clary, Bryan, Singh, Shree Ram, Ye, Jianxin, Hoffman, Robert M
Published 2020