Color-coded chemotherapy: S/G2-phase-trapping by methioninase pre-treatment, indicated by FUCCI imaging, enables highly effective cancer chemotherapy

by Yano, Shuya, Tome, Yasunori, Digman, Michelle, Momiyama, Masashi, Suetsugu, Atsushi, Gratton, Enrico, Hoffman, Robert
Published 2014

Adenoviral targeting of malignant melanoma for fluorescence-guided surgery prevents recurrence in orthotopic nude-mouse models.

by Yano, Shuya, Takehara, Kiyoto, Kishimoto, Hiroyuki, Urata, Yasuo, Kagawa, Shunsuke, Bouvet, Michael, Fujiwara, Toshiyoshi, Hoffman, Robert M
Published 2016

Tumor-targeting Salmonella typhimurium A1-R prevents experimental human breast cancer bone metastasis in nude mice.

by Miwa, Shinji, Yano, Shuya, Zhang, Yong, Matsumoto, Yasunori, Uehara, Fuminari, Yamamoto, Mako, Hiroshima, Yukihiko, Kimura, Hiroaki, Hayashi, Katsuhiro, Yamamoto, Norio, Bouvet, Michael, Tsuchiya, Hiroyuki, Hoffman, Robert M, Zhao, Ming
Published 2014

Precise navigation surgery of tumours in the lung in mouse models enabled by in situ fluorescence labelling with a killer-reporter adenovirus.

by Yano, Shuya, Zhang, Yong, Miwa, Shinji, Kishimoto, Hiroyuki, Urata, Yasuo, Bouvet, Michael, Kagawa, Shunsuke, Fujiwara, Toshiyoshi, Hoffman, Robert M
Published 2015

Fluorescence-guided surgery of a highly-metastatic variant of human triple-negative breast cancer targeted with a cancer-specific GFP adenovirus prevents recurrence.

by Yano, Shuya, Takehara, Kiyoto, Miwa, Shinji, Kishimoto, Hiroyuki, Tazawa, Hiroshi, Urata, Yasuo, Kagawa, Shunsuke, Bouvet, Michael, Fujiwara, Toshiyoshi, Hoffman, Robert M
Published 2016

Tumor-Targeting Salmonella typhimurium A1-R Arrests a Chemo-Resistant Patient Soft-Tissue Sarcoma in Nude Mice.

by Hiroshima, Yukihiko, Zhao, Ming, Zhang, Yong, Zhang, Nan, Maawy, Ali, Murakami, Takashi, Mii, Sumiyuki, Uehara, Fuminari, Yamamoto, Mako, Miwa, Shinji, Yano, Shuya, Momiyama, Masashi, Mori, Ryutaro, Matsuyama, Ryusei, Chishima, Takashi, Tanaka, Kuniya, Ichikawa, Yasushi, Bouvet, Michael, Endo, Itaru, Hoffman, Robert M
Published 2015

Establishment of a patient-derived orthotopic Xenograft (PDOX) model of HER-2-positive cervical cancer expressing the clinical metastatic pattern.

by Hiroshima, Yukihiko, Zhang, Yong, Zhang, Nan, Maawy, Ali, Mii, Sumiyuki, Yamamoto, Mako, Uehara, Fuminari, Miwa, Shinji, Yano, Shuya, Murakami, Takashi, Momiyama, Masashi, Chishima, Takashi, Tanaka, Kuniya, Ichikawa, Yasushi, Bouvet, Michael, Murata, Takuya, Endo, Itaru, Hoffman, Robert M
Published 2015

Imaging of methioninase-induced S/G(2)-phase-trapping for subsequent effective chemotherapy

by Yano, Shuya, Tome, Yasunori, Digman, Michelle, Momiyamal, Masashi, Suetsugu, Atsushi, Gratton, Enrico, Hoffman, Robert M
Published 2013

Tumor-targeting Salmonella typhimurium A1-R inhibits human prostate cancer experimental bone metastasis in mouse models.

by Toneri, Makoto, Miwa, Shinji, Zhang, Yong, Hu, Cameron, Yano, Shuya, Matsumoto, Yasunori, Bouvet, Michael, Nakanishi, Hayao, Hoffman, Robert M, Zhao, Ming
Published 2015

Efficacy of tumor-targeting Salmonella typhimurium A1-R in combination with anti-angiogenesis therapy on a pancreatic cancer patient-derived orthotopic xenograft (PDOX) and cell li...

by Hiroshima, Yukihiko, Zhang, Yong, Murakami, Takashi, Maawy, Ali, Miwa, Shinji, Yamamoto, Mako, Yano, Shuya, Sato, Sho, Momiyama, Masashi, Mori, Ryutaro, Matsuyama, Ryusei, Chishima, Takashi, Tanaka, Kuniya, Ichikawa, Yasushi, Bouvet, Michael, Endo, Itaru, Zhao, Ming, Hoffman, Robert M
Published 2014

Targeting tumors with a killer-reporter adenovirus for curative fluorescence-guided surgery of soft-tissue sarcoma.

by Yano, Shuya, Miwa, Shinji, Kishimoto, Hiroyuki, Uehara, Fuminari, Tazawa, Hiroshi, Toneri, Makoto, Hiroshima, Yukihiko, Yamamoto, Mako, Urata, Yasuo, Kagawa, Shunsuke, Bouvet, Michael, Fujiwara, Toshiyoshi, Hoffman, Robert M
Published 2015

Intraperitoneal administration of tumor-targeting Salmonella typhimurium A1-R inhibits disseminated human ovarian cancer and extends survival in nude mice.

by Matsumoto, Yasunori, Miwa, Shinji, Zhang, Yong, Zhao, Ming, Yano, Shuya, Uehara, Fuminari, Yamamoto, Mako, Hiroshima, Yukihiko, Toneri, Makoto, Bouvet, Michael, Matsubara, Hisahiro, Tsuchiya, Hiroyuki, Hoffman, Robert M
Published 2015

Selective methioninase-induced trap of cancer cells in S/G2 phase visualized by FUCCI imaging confers chemosensitivity.

by Yano, Shuya, Li, Shukuan, Han, Qinghong, Tan, Yuying, Bouvet, Michael, Fujiwara, Toshiyoshi, Hoffman, Robert M
Published 2014

Inhibition of spontaneous and experimental lung metastasis of soft-tissue sarcoma by tumor-targeting Salmonella typhimurium A1-R.

by Miwa, Shinji, Zhang, Yong, Baek, Kyung-Eun, Uehara, Fuminari, Yano, Shuya, Yamamoto, Mako, Hiroshima, Yukihiko, Matsumoto, Yasunori, Kimura, Hiroaki, Hayashi, Katsuhiro, Yamamoto, Norio, Bouvet, Michael, Tsuchiya, Hiroyuki, Hoffman, Robert M, Zhao, Ming
Published 2014

Fluorescence-guided surgery of retroperitoneal-implanted human fibrosarcoma in nude mice delays or eliminates tumor recurrence and increases survival compared to bright-light surge...

by Uehara, Fuminari, Hiroshima, Yukihiko, Miwa, Shinji, Tome, Yasunori, Yano, Shuya, Yamamoto, Mako, Matsumoto, Yasunori, Maehara, Hiroki, Tanaka, Kazuhiro, Bouvet, Michael, Kanaya, Fuminori, Hoffman, Robert M
Published 2015

The tumor-educated-macrophage increase of malignancy of human pancreatic cancer is prevented by zoledronic acid.

by Hiroshima, Yukihiko, Maawy, Ali, Hassanein, Mohamed K, Menen, Rhiana, Momiyama, Masashi, Murakami, Takashi, Miwa, Shinji, Yamamoto, Mako, Uehara, Fuminari, Yano, Shuya, Mori, Ryutaro, Matsuyama, Ryusei, Chishima, Takashi, Tanaka, Kuniya, Ichikawa, Yasushi, Bouvet, Michael, Endo, Itaru, Hoffman, Robert M
Published 2014

Traditional Chinese medicine herbal mixture LQ arrests FUCCI-expressing HeLa cells in G₀/G₁ phase in 2D plastic, 2.5D Matrigel, and 3D Gelfoam culture visualized with FUCCI imaging...

by Zhang, Lei, Wu, Chengyu, Bouvet, Michael, Yano, Shuya, Hoffman, Robert M
Published 2015

Tumor-targeting adenovirus OBP-401 inhibits primary and metastatic tumor growth of triple-negative breast cancer in orthotopic nude-mouse models.

by Yano, Shuya, Takehara, Kiyoto, Kishimoto, Hiroyuki, Tazawa, Hiroshi, Urata, Yasuo, Kagawa, Shunsuke, Bouvet, Michael, Fujiwara, Toshiyoshi, Hoffman, Robert M
Published 2016

Fluorescence-guided surgery in combination with UVC irradiation cures metastatic human pancreatic cancer in orthotopic mouse models.

by Hiroshima, Yukihiko, Maawy, Ali, Zhang, Yong, Sato, Sho, Murakami, Takashi, Yamamoto, Mako, Uehara, Fuminari, Miwa, Shinji, Yano, Shuya, Momiyama, Masashi, Chishima, Takashi, Tanaka, Kuniya, Bouvet, Michael, Endo, Itaru, Hoffman, Robert M
Published 2014

Tumor-Targeting Salmonella typhimurium A1-R in Combination with Trastuzumab Eradicates HER-2-Positive Cervical Cancer Cells in Patient-Derived Mouse Models.

by Hiroshima, Yukihiko, Zhang, Yong, Zhao, Ming, Zhang, Nan, Murakami, Takashi, Maawy, Ali, Mii, Sumiyuki, Uehara, Fuminari, Yamamoto, Mako, Miwa, Shinji, Yano, Shuya, Momiyama, Masashi, Mori, Ryutaro, Matsuyama, Ryusei, Chishima, Takashi, Tanaka, Kuniya, Ichikawa, Yasushi, Bouvet, Michael, Endo, Itaru, Hoffman, Robert M
Published 2015