Osimertinib Regresses an EGFR-Mutant Cisplatinum- Resistant Lung Adenocarcinoma Growing in the Brain in Nude Mice.

by Higuchi, Takashi, Oshiro, Hiromichi, Zhang, Zhiying, Miyake, Kentaro, Sugisawa, Norihiko, Katsuya, Yuki, Yamamoto, Norio, Hayashi, Katsuhiro, Kimura, Hiroaki, Miwa, Shinji, Igarashi, Kentaro, Zhao, Ming, Bouvet, Michael, Singh, Shree Ram, Tsuchiya, Hiroyuki, Hoffman, Robert M
Published 2019

Osimertinib regressed an EGFR-mutant lung-adenocarcinoma bone-metastasis mouse model and increased long-term survival.

by Higuchi, Takashi, Sugisawa, Norihiko, Park, Jun Ho, Sun, Yu, Zhu, Guangwei, Yamamoto, Norio, Hayashi, Katsuhiro, Kimura, Hiroaki, Miwa, Shinji, Igarashi, Kentaro, Bouvet, Michael, Singh, Shree Ram, Tsuchiya, Hiroyuki, Hoffman, Robert M
Published 2020

The Combination of Olaratumab with Doxorubicin and Cisplatinum Regresses a Chemotherapy-Resistant Osteosarcoma in a Patient-Derived Orthotopic Xenograft Mouse Model.

by Higuchi, Takashi, Sugisawa, Norihiko, Miyake, Kentaro, Oshiro, Hiromichi, Yamamoto, Norio, Hayashi, Katsuhiro, Kimura, Hiroaki, Miwa, Shinji, Igarashi, Kentaro, Bouvet, Michael, Singh, Shree Ram, Tsuchiya, Hiroyuki, Hoffman, Robert M
Published 2019

Patient-derived orthotopic xenograft models for cancer of unknown primary precisely distinguish chemotherapy, and tumor-targeting S. typhimurium A1-R is superior to first-line chem...

by Miyake, Kentaro, Kiyuna, Tasuku, Miyake, Masuyo, Kawaguchi, Kei, Yoon, Sang Nam, Zhang, Zhiying, Igarashi, Kentaro, Razmjooei, Sahar, Wangsiricharoen, Sintawat, Murakami, Takashi, Li, Yunfeng, Nelson, Scott D, Russell, Tara A, Singh, Arun S, Hiroshima, Yukihiko, Momiyama, Masashi, Matsuyama, Ryusei, Chishima, Takashi, Singh, Shree Ram, Endo, Itaru, Eilber, Fritz C, Hoffman, Robert M
Published 2018

Hair-follicle-associated pluripotent stem cells derived from cryopreserved intact human hair follicles sustain multilineage differentiation potential.

by Obara, Koya, Tohgi, Natsuko, Mii, Sumiyuki, Hamada, Yuko, Arakawa, Nobuko, Aki, Ryoichi, Singh, Shree Ram, Hoffman, Robert M, Amoh, Yasuyuki
Published 2019

MUC1 selectively targets human pancreatic cancer in orthotopic nude mouse models.

by Park, Jeong Youp, Hiroshima, Yukihiko, Lee, Jin Young, Maawy, Ali A, Hoffman, Robert M, Bouvet, Michael
Published 2015

Doubly Optimized Calibrated Support Vector Machine (DOC-SVM): an algorithm for joint optimization of discrimination and calibration.

by Jiang, Xiaoqian, Menon, Aditya, Wang, Shuang, Kim, Jihoon, Ohno-Machado, Lucila
Published 2012

Tumor-targeting Salmonella typhimurium A1-R suppressed an imatinib-resistant gastrointestinal stromal tumor with c-kit exon 11 and 17 mutations.

by Miyake, Kentaro, Kawaguchi, Kei, Miyake, Masuyo, Zhao, Ming, Kiyuna, Tasuku, Igarashi, Kentaro, Zhang, Zhiying, Murakami, Takashi, Li, Yunfeng, Nelson, Scott D, Bouvet, Michael, Elliott, Irmina, Russell, Tara A, Singh, Arun S, Hiroshima, Yukihiko, Momiyama, Masashi, Matsuyama, Ryusei, Chishima, Takashi, Singh, Shree Ram, Endo, Itaru, Eilber, Fritz C, Hoffman, Robert M
Published 2018

Polyethylene glycol (PEG) linked to near infrared (NIR) dyes conjugated to chimeric anti-carcinoembryonic antigen (CEA) antibody enhances imaging of liver metastases in a nude-mous...

by Maawy, Ali A, Hiroshima, Yukihiko, Zhang, Yong, Luiken, George A, Hoffman, Robert M, Bouvet, Michael
Published 2014

Temozolomide and Pazopanib Combined with FOLFOX Regressed a Primary Colorectal Cancer in a Patient-derived Orthotopic Xenograft Mouse Model.

by Zhu, Guangwei, Zhao, Ming, Han, Qinghong, Tan, Yuying, Sun, Yu, Bouvet, Michael, Clary, Bryan, Singh, Shree Ram, Ye, Jianxin, Hoffman, Robert M
Published 2020

Exquisite Tumor Targeting by Salmonella A1-R in Combination with Caffeine and Valproic Acid Regresses an Adult Pleomorphic Rhabdomyosarcoma Patient-Derived Orthotopic Xenograft Mou...

by Igarashi, Kentaro, Kawaguchi, Kei, Zhao, Ming, Kiyuna, Tasuku, Miyake, Kentaro, Miyake, Masuyo, Nelson, Scott D, Dry, Sarah M, Li, Yunfeng, Yamamoto, Norio, Hayashi, Katsuhiro, Kimura, Hiroaki, Miwa, Shinji, Higuchi, Takashi, Singh, Shree Ram, Tsuchiya, Hiroyuki, Hoffman, Robert M
Published 2020

Ischemia reperfusion-induced metastasis is resistant to PPARγ agonist pioglitazone in a murine model of colon cancer.

by Tashiro, Yoshihiko, Nishino, Hiroto, Higuchi, Takashi, Sugisawa, Norihiko, Fukuda, Yasunari, Yamamoto, Jun, Inubushi, Sachiko, Aoki, Takeshi, Murakami, Masahiko, Singh, Shree Ram, Bouvet, Michael, Hoffman, Robert M
Published 2020

Trabectedin arrests a doxorubicin-resistant PDGFRA-activated liposarcoma patient-derived orthotopic xenograft (PDOX) nude mouse model.

by Kiyuna, Tasuku, Tome, Yasunori, Murakami, Takashi, Kawaguchi, Kei, Igarashi, Kentaro, Miyake, Kentaro, Miyake, Masuyo, Li, Yunfeng, Nelson, Scott D, Dry, Sarah M, Singh, Arun S, Russell, Tara A, Elliott, Irmina, Singh, Shree Ram, Kanaya, Fuminori, Eilber, Fritz C, Hoffman, Robert M
Published 2018

The relationship between total bilirubin levels and total mortality in older adults: the United States National Health and Nutrition Examination Survey (NHANES) 1999-2004.

by Ong, Kwok-Leung, Allison, Matthew A, Cheung, Bernard MY, Wu, Ben J, Barter, Philip J, Rye, Kerry-Anne
Published 2014

Metastatic recurrence in a pancreatic cancer patient derived orthotopic xenograft (PDOX) nude mouse model is inhibited by neoadjuvant chemotherapy in combination with fluorescence-...

by Hiroshima, Yukihiko, Maawy, Ali, Zhang, Yong, Murakami, Takashi, Momiyama, Masashi, Mori, Ryutaro, Matsuyama, Ryusei, Katz, Matthew HG, Fleming, Jason B, Chishima, Takashi, Tanaka, Kuniya, Ichikawa, Yasushi, Endo, Itaru, Hoffman, Robert M, Bouvet, Michael
Published 2014

Ethanol negatively regulates hepatic differentiation of hESC by inhibition of the MAPK/ERK signaling pathway in vitro.

by Gao, Wei, Zhou, Ping, Ma, Xiaocui, Tschudy-Seney, Benjamin, Chen, Jiamei, Magner, Nataly L, Revzin, Alexander, Nolta, Jan A, Zern, Mark A, Duan, Yuyou
Published 2014