Oxidative stress and protein damage responses mediate artemisinin resistance in malaria parasites.

by Frances Rocamora, Lei Zhu, Kek Yee Liong, Arjen Dondorp, Olivo Miotto, Sachel Mok, Zbynek Bozdech
Published 2018-03-01

Semi-Synthetic Analogues of Cryptolepine as a Potential Source of Sustainable Drugs for the Treatment of Malaria, Human African Trypanosomiasis, and Cancer

by Yabalu Z. Abacha, Yabalu Z. Abacha, Arnold Donkor Forkuo, Stephen Y. Gbedema, Nimisha Mittal, Sabine Ottilie, Frances Rocamora, Elizabeth A. Winzeler, Donelly A. van Schalkwyk, John M. Kelly, Martin C. Taylor, Janette Reader, Lyn-Marie Birkholtz, David R. Lisgarten, Jeremy K. Cockcroft, John N. Lisgarten, Rex A. Palmer, Rosemary C. Talbert, Steven D. Shnyder, Colin W. Wright
Published 2022-04-01

Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway

by Gregory M. LaMonte, Frances Rocamora, Danushka S. Marapana, Nina F. Gnädig, Sabine Ottilie, Madeline R. Luth, Tilla S. Worgall, Gregory M. Goldgof, Roxanne Mohunlal, T. R. Santha Kumar, Jennifer K. Thompson, Edgar Vigil, Jennifer Yang, Dylan Hutson, Trevor Johnson, Jianbo Huang, Roy M. Williams, Bing Yu Zou, Andrea L. Cheung, Prianka Kumar, Timothy J. Egan, Marcus C. S. Lee, Dionicio Siegel, Alan F. Cowman, David A. Fidock, Elizabeth A. Winzeler
Published 2020-04-01