Vinaxanthone inhibits Semaphorin3A induced axonal growth cone collapse in embryonic neurons but fails to block its growth promoting effects on adult neurons

by Evguenia Ivakhnitskaia, Matthew R. Chin, Dionicio Siegel, Victor H. Guaiquil
Published 2021-06-01

In Vitro Efficacy of Ebselen and BAY 11-7082 Against Naegleria fowleri

by Anjan Debnath, Andrew T. Nelson, Angélica Silva-Olivares, Mineko Shibayama, Dionicio Siegel, James H. McKerrow
Published 2018-03-01

Distinct biological activities of isomers from several families of branched fatty acid esters of hydroxy fatty acids (FAHFAs)

by Pratik Aryal, Ismail Syed, Jennifer Lee, Rucha Patel, Andrew T. Nelson, Dionicio Siegel, Alan Saghatelian, Barbara B. Kahn
Published 2021-01-01

Targeting of REST with rationally-designed small molecule compounds exhibits synergetic therapeutic potential in human glioblastoma cells

by Svetlana B. Panina, Joshua V. Schweer, Qian Zhang, Gaurav Raina, Haley A. Hardtke, Seungjin Kim, Wanjie Yang, Dionicio Siegel, Y. Jessie Zhang
Published 2024-04-01

Mechanistic insights gained from cell and molecular analysis of the neuroprotective potential of bioactive natural compounds in an immortalized hippocampal cell line

by Harris A. Weisz, Deborah R. Boone, William S. Coggins, Gabrielle A. Edwards, Hannah E. Willey, Steven G. Widen, Dionicio Siegel, Andrew T. Nelson, Donald S. Prough, Helen L. Hellmich
Published 2022-01-01

Mechanistic insights gained from cell and molecular analysis of the neuroprotective potential of bioactive natural compounds in an immortalized hippocampal cell line.

by Harris A Weisz, Deborah R Boone, William S Coggins, Gabrielle A Edwards, Hannah E Willey, Steven G Widen, Dionicio Siegel, Andrew T Nelson, Donald S Prough, Helen L Hellmich
Published 2022-01-01

Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway

by Gregory M. LaMonte, Frances Rocamora, Danushka S. Marapana, Nina F. Gnädig, Sabine Ottilie, Madeline R. Luth, Tilla S. Worgall, Gregory M. Goldgof, Roxanne Mohunlal, T. R. Santha Kumar, Jennifer K. Thompson, Edgar Vigil, Jennifer Yang, Dylan Hutson, Trevor Johnson, Jianbo Huang, Roy M. Williams, Bing Yu Zou, Andrea L. Cheung, Prianka Kumar, Timothy J. Egan, Marcus C. S. Lee, Dionicio Siegel, Alan F. Cowman, David A. Fidock, Elizabeth A. Winzeler
Published 2020-04-01