Ancient Chinese Methods Are Remarkably Effective for the Preparation of Artemisinin-Rich Extracts of Qing Hao with Potent Antimalarial Activity

by Elisabeth Hsu, Sergio Wittlin, Reto Brun, Peter A. Linley, Colin W. Wright
Published 2010-02-01

A methanolic extract of Zanthoxylum bungeanum modulates secondary metabolism regulator genes in Aspergillus flavus and shuts down aflatoxin production

by Asmaa Abbas, Colin W. Wright, Nagwa El-Sawi, Tapani Yli-Mattila, Anssi M. Malinen
Published 2022-04-01

In vitro anti-malarial interaction and gametocytocidal activity of cryptolepine

by Arnold Donkor Forkuo, Charles Ansah, Kwesi Boadu Mensah, Kofi Annan, Ben Gyan, Anjo Theron, Dalu Mancama, Colin W. Wright
Published 2017-12-01

Identification of cryptolepine metabolites in rat and human hepatocytes and metabolism and pharmacokinetics of cryptolepine in Sprague Dawley rats

by Arnold Donkor Forkuo, Charles Ansah, David Pearson, Werner Gertsch, Amanda Cirello, Adam Amaral, Jaimie Spear, Colin W. Wright, Caroline Rynn
Published 2017-12-01

Semi-Synthetic Analogues of Cryptolepine as a Potential Source of Sustainable Drugs for the Treatment of Malaria, Human African Trypanosomiasis, and Cancer

by Yabalu Z. Abacha, Yabalu Z. Abacha, Arnold Donkor Forkuo, Stephen Y. Gbedema, Nimisha Mittal, Sabine Ottilie, Frances Rocamora, Elizabeth A. Winzeler, Donelly A. van Schalkwyk, John M. Kelly, Martin C. Taylor, Janette Reader, Lyn-Marie Birkholtz, David R. Lisgarten, Jeremy K. Cockcroft, John N. Lisgarten, Rex A. Palmer, Rosemary C. Talbert, Steven D. Shnyder, Colin W. Wright
Published 2022-04-01

Machine learning enhances prediction of plants as potential sources of antimalarials

by Adam Richard-Bollans, Conal Aitken, Conal Aitken, Alexandre Antonelli, Alexandre Antonelli, Alexandre Antonelli, Cássia Bitencourt, David Goyder, Eve Lucas, Ian Ondo, Oscar A. Pérez-Escobar, Samuel Pironon, Samuel Pironon, James E. Richardson, James E. Richardson, James E. Richardson, James E. Richardson, David Russell, Daniele Silvestro, Daniele Silvestro, Daniele Silvestro, Colin W. Wright, Melanie-Jayne R. Howes, Melanie-Jayne R. Howes
Published 2023-05-01

Cross-species oncogenomics offers insight into human muscle-invasive bladder cancer

by Kim Wong, Federico Abascal, Latasha Ludwig, Heike Aupperle-Lellbach, Julia Grassinger, Colin W. Wright, Simon J. Allison, Emma Pinder, Roger M. Phillips, Laura P. Romero, Arnon Gal, Patrick J. Roady, Isabel Pires, Franco Guscetti, John S. Munday, Maria C. Peleteiro, Carlos A. Pinto, Tânia Carvalho, João Cota, Elizabeth C. Du Plessis, Fernando Constantino-Casas, Stephanie Plog, Lars Moe, Simone de Brot, Ingrid Bemelmans, Renée Laufer Amorim, Smitha R. Georgy, Justina Prada, Jorge del Pozo, Marianne Heimann, Louisiane de Carvalho Nunes, Outi Simola, Paolo Pazzi, Johan Steyl, Rodrigo Ubukata, Peter Vajdovich, Simon L. Priestnall, Alejandro Suárez-Bonnet, Franco Roperto, Francesca Millanta, Chiara Palmieri, Ana L. Ortiz, Claudio S. L. Barros, Aldo Gava, Minna E. Söderström, Marie O’Donnell, Robert Klopfleisch, Andrea Manrique-Rincón, Inigo Martincorena, Ingrid Ferreira, Mark J. Arends, Geoffrey A. Wood, David J. Adams, Louise van der Weyden
Published 2023-08-01