MicroRNAs: At the Interface of Metabolic Pathways and Inflammatory Responses by Macrophages

by Morgan C. Nelson, Morgan C. Nelson, Ryan M. O'Connell, Ryan M. O'Connell
Published 2020-08-01

miR-aculous new avenues for cancer immunotherapy

by William W. Tang, William W. Tang, Kaylyn M. Bauer, Kaylyn M. Bauer, Cindy Barba, Cindy Barba, Huseyin Atakan Ekiz, Ryan M. O’Connell, Ryan M. O’Connell
Published 2022-09-01

CIPR: a web-based R/shiny app and R package to annotate cell clusters in single cell RNA sequencing experiments

by H. Atakan Ekiz, Christopher J. Conley, W. Zac Stephens, Ryan M. O’Connell
Published 2020-05-01

MicroRNA-146a acts as a guardian of the quality and longevity of hematopoietic stem cells in mice

by Jimmy L Zhao, Dinesh S Rao, Ryan M O’Connell, Yvette Garcia-Flores, David Baltimore
Published 2013-05-01

Targeting human microRNA genes using engineered Tal-effector nucleases (TALENs).

by Ruozhen Hu, Jared Wallace, Timothy J Dahlem, David Jonah Grunwald, Ryan M O'Connell
Published 2013-01-01

Lentiviral vector delivery of human interleukin-7 (hIL-7) to human immune system (HIS) mice expands T lymphocyte populations.

by Ryan M O'Connell, Alejandro B Balazs, Dinesh S Rao, Christine Kivork, Lili Yang, David Baltimore
Published 2010-08-01

miRNA-1 promotes acute myeloid leukemia cell pathogenesis through metabolic regulation

by Arevik Ghazaryan, Jared A. Wallace, William W. Tang, Cindy Barba, Soh-Hyun Lee, Kaylyn M. Bauer, Morgan C. Nelson, Carissa N. Kim, Chris Stubben, Warren P. Voth, Dinesh S. Rao, Ryan M. O’Connell, Ryan M. O’Connell
Published 2023-05-01

Antagonistic Interplay between MicroRNA-155 and IL-10 during Lyme Carditis and Arthritis.

by Robert B Lochhead, James F Zachary, Luciana Dalla Rosa, Ying Ma, John H Weis, Ryan M O'Connell, Janis J Weis
Published 2015-01-01

Genome-Wide CRISPR-Cas9 Screen Identifies MicroRNAs That Regulate Myeloid Leukemia Cell Growth.

by Jared Wallace, Ruozhen Hu, Timothy L Mosbruger, Timothy J Dahlem, W Zac Stephens, Dinesh S Rao, June L Round, Ryan M O'Connell
Published 2016-01-01

MicroRNA-146a provides feedback regulation of lyme arthritis but not carditis during infection with Borrelia burgdorferi.

by Robert B Lochhead, Ying Ma, James F Zachary, David Baltimore, Jimmy L Zhao, John H Weis, Ryan M O'Connell, Janis J Weis
Published 2014-06-01

Epistasis between MicroRNAs 155 and 146a during T Cell-Mediated Antitumor Immunity

by Thomas B. Huffaker, Ruozhen Hu, Marah C. Runtsch, Erin Bake, Xinjian Chen, Jimmy Zhao, June L. Round, David Baltimore, Ryan M. O'Connell
Published 2012-12-01

Interferon α-induced SAMHD1 regulates human cultured megakaryocyte apoptosis and proplatelet formation

by Seema Bhatlekar, Shancy Jacob, Emilia Tugolukova, Bhanu K. Manne, Yasuhiro Kosaka, Phillipe Loher, Ryan M. O’Connell, Vicente Planelles, Matthew T. Rondina, Isidore Rigoutsos, Paul F. Bray
Published 2021-11-01

The miR-26b-5p/KPNA2 Axis Is an Important Regulator of Burkitt Lymphoma Cell Growth

by Fubiao Niu, Marta Kazimierska, Ilja M. Nolte, Miente Martijn Terpstra, Debora de Jong, Jasper Koerts, Tineke van der Sluis, Bea Rutgers, Ryan M. O’Connell, Klaas Kok, Anke van den Berg, Agnieszka Dzikiewicz-Krawczyk, Joost Kluiver
Published 2020-06-01

Mitochondrial Pyruvate Carrier 1 Promotes Peripheral T Cell Homeostasis through Metabolic Regulation of Thymic Development

by Andrew G. Ramstead, Jared A. Wallace, Soh-Hyun Lee, Kaylyn M. Bauer, William W. Tang, H. Atakan Ekiz, Thomas E. Lane, Ahmad A. Cluntun, Matthew L. Bettini, June L. Round, Jared Rutter, Ryan M. O’Connell
Published 2020-03-01

Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition

by W. Zac Stephens, Jason L. Kubinak, Arevik Ghazaryan, Kaylyn M. Bauer, Rickesha Bell, Kate Buhrke, Tyson R. Chiaro, Allison M. Weis, William W. Tang, Josh K. Monts, Ray Soto, H. Atakan Ekiz, Ryan M. O’Connell, June L. Round
Published 2021-11-01

RAB27B controls palmitoylation-dependent NRAS trafficking and signaling in myeloid leukemia

by Jian-Gang Ren, Bowen Xing, Kaosheng Lv, Rachel A. O’Keefe, Mengfang Wu, Ruoxing Wang, Kaylyn M. Bauer, Arevik Ghazaryan, George M. Burslem, Jing Zhang, Ryan M. O’Connell, Vinodh Pillai, Elizabeth O. Hexner, Mark R. Philips, Wei Tong
Published 2023-06-01

A Stat1 bound enhancer promotes Nampt expression and function within tumor associated macrophages

by Thomas B. Huffaker, H. Atakan Ekiz, Cindy Barba, Soh-Hyun Lee, Marah C. Runtsch, Morgan C. Nelson, Kaylyn M. Bauer, William W. Tang, Timothy L. Mosbruger, James E. Cox, June L. Round, Warren P. Voth, Ryan M. O’Connell
Published 2021-05-01

The microbiota protects from viral-induced neurologic damage through microglia-intrinsic TLR signaling

by D Garrett Brown, Raymond Soto, Soumya Yandamuri, Colleen Stone, Laura Dickey, Joao Carlos Gomes-Neto, Elissa D Pastuzyn, Rickesha Bell, Charisse Petersen, Kaitlin Buhrke, Robert S Fujinami, Ryan M O'Connell, W Zac Stephens, Jason D Shepherd, Thomas E Lane, June L Round
Published 2019-07-01

Anti-inflammatory microRNA-146a protects mice from diet-induced metabolic disease.

by Marah C Runtsch, Morgan C Nelson, Soh-Hyun Lee, Warren Voth, Margaret Alexander, Ruozhen Hu, Jared Wallace, Charisse Petersen, Vanja Panic, Claudio J Villanueva, Kimberley J Evason, Kaylyn M Bauer, Timothy Mosbruger, Sihem Boudina, Mary Bronner, June L Round, Micah J Drummond, Ryan M O'Connell
Published 2019-02-01

Pyruvate metabolism controls chromatin remodeling during CD4+ T cell activation

by Enric Mocholi, Laura Russo, Keshav Gopal, Andrew G. Ramstead, Sophia M. Hochrein, Harmjan R. Vos, Geert Geeven, Adeolu O. Adegoke, Anna Hoekstra, Robert M. van Es, Jose Ramos Pittol, Sebastian Vastert, Jared Rutter, Timothy Radstake, Jorg van Loosdregt, Celia Berkers, Michal Mokry, Colin C. Anderson, Ryan M. O’Connell, Martin Vaeth, John Ussher, Boudewijn M.T. Burgering, Paul J. Coffer
Published 2023-06-01