Colorectal Cancer-Infiltrating Regulatory T Cells: Functional Heterogeneity, Metabolic Adaptation, and Therapeutic Targeting

by Sonia Aristin Revilla, Sonia Aristin Revilla, Sonia Aristin Revilla, Onno Kranenburg, Paul J. Coffer, Paul J. Coffer
Published 2022-07-01

Forkhead box protein P1, a key player in neuronal development?

by Luca Braccioli, Cora H Nijboer, Paul J Coffer
Published 2018-01-01

Ectopic expression of C/EBPα and ID1 is sufficient to restore defective neutrophil development in low-risk myelodysplasia

by Christian R. Geest, Miranda Buitenhuis, Edo Vellenga, Paul J. Coffer
Published 2009-08-01

SOX4 mediates TGF-β-induced expression of mesenchymal markers during mammary cell epithelial to mesenchymal transition.

by Stephin J Vervoort, Ana Rita Lourenço, Ruben van Boxtel, Paul J Coffer
Published 2013-01-01

Histone deacetylase inhibition modulates cell fate decisions during myeloid differentiation

by Marije Bartels, Christian R. Geest, Marc Bierings, Miranda Buitenhuis, Paul J. Coffer
Published 2010-07-01

Mammalian target of rapamycin activity is required for expansion of CD34+ hematopoietic progenitor cells

by Christian R. Geest, Fried J. Zwartkruis, Edo Vellenga, Paul J. Coffer, Miranda Buitenhuis
Published 2009-07-01

SOX4 inhibits oligodendrocyte differentiation of embryonic neural stem cells in vitro by inducing Hes5 expression

by Luca Braccioli, Stephin J. Vervoort, Gianmarco Puma, Cora H. Nijboer, Paul J. Coffer
Published 2018-12-01

Rapid temporal control of Foxp3 protein degradation by sirtuin-1.

by Jorg van Loosdregt, Diede Brunen, Veerle Fleskens, Cornelieke E G M Pals, Eric W F Lam, Paul J Coffer
Published 2011-04-01

FOXP1 Promotes Embryonic Neural Stem Cell Differentiation by Repressing Jagged1 Expression

by Luca Braccioli, Stephin J. Vervoort, Youri Adolfs, Cobi J. Heijnen, Onur Basak, R. Jeroen Pasterkamp, Cora H. Nijboer, Paul J. Coffer
Published 2017-11-01

Co-expression of the collagen receptors leukocyte-associated immunoglobulin-like receptor-1 and glycoprotein VI on a subset of megakaryoblasts

by Tessa A.M. Steevels, Geertje H.A. Westerlaken, Marloes R. Tijssen, Paul J. Coffer, Peter J. Lenting, Jan Willem N. Akkerman, Linde Meyaard
Published 2010-12-01

Differential effects of nitrostyrene derivatives on myelopoiesis involve regulation of C/EBPα and p38MAPK activity.

by Marije Bartels, Andrana K Calgarotto, Anton C Martens, Victor Maso, Saulo L da Silva, Marc B Bierings, Mary L de Souza Queiroz, Paul J Coffer
Published 2014-01-01

Transcriptomic and Epigenomic Profiling of Histone Deacetylase Inhibitor Treatment Reveals Distinct Gene Regulation Profiles Leading to Impaired Neutrophil Development

by Anita M.A.P. Govers, Caroline R.M. Wiggers, Ruben van Boxtel, Michal Mokry, Edward E.S. Nieuwenhuis, Menno P. Creyghton, Marije Bartels, Paul J. Coffer
Published 2019-08-01

C/EBPɑ is crucial determinant of epithelial maintenance by preventing epithelial-to-mesenchymal transition

by Ana Rita Lourenço, M. Guy Roukens, Danielle Seinstra, Cynthia L. Frederiks, Cornelieke E. Pals, Stephin J. Vervoort, Andreia S. Margarido, Jacco van Rheenen, Paul J. Coffer
Published 2020-02-01

Context-Specific Effects of TGF-β/SMAD3 in Cancer Are Modulated by the Epigenome

by Ana Tufegdzic Vidakovic, Oscar M. Rueda, Stephin J. Vervoort, Ankita Sati Batra, Mae Akilina Goldgraben, Santiago Uribe-Lewis, Wendy Greenwood, Paul J. Coffer, Alejandra Bruna, Carlos Caldas
Published 2015-12-01

In Vitro Evaluation of Spider Silk Meshes as a Potential Biomaterial for Bladder Reconstruction.

by Anne Steins, Pieter Dik, Wally H Müller, Stephin J Vervoort, Kerstin Reimers, Jörn W Kuhbier, Peter M Vogt, Aart A van Apeldoorn, Paul J Coffer, Koen Schepers
Published 2015-01-01

In vitro induction of alkaline phosphatase levels predicts in vivo bone forming capacity of human bone marrow stromal cells

by Henk-Jan Prins, A. Koen Braat, D. Gawlitta, Wouter J.A. Dhert, David A. Egan, Estel Tijssen-Slump, Huipin Yuan, Paul J. Coffer, Henk Rozemuller, Anton C. Martens
Published 2014-03-01

STAT3 regulates monocyte TNF-alpha production in systemic inflammation caused by cardiac surgery with cardiopulmonary bypass.

by Petrus R de Jong, Alvin W L Schadenberg, Theo van den Broek, Jeffrey M Beekman, Femke van Wijk, Paul J Coffer, Berent J Prakken, Nicolaas J G Jansen
Published 2012-01-01

Chemotherapy-induced intestinal epithelial damage directly promotes galectin-9-driven modulation of T cell behavior

by Suze A. Jansen, Alessandro Cutilli, Coco de Koning, Marliek van Hoesel, Cynthia L. Frederiks, Leire Saiz Sierra, Stefan Nierkens, Michal Mokry, Edward E.S. Nieuwenhuis, Alan M. Hanash, Enric Mocholi, Paul J. Coffer, Caroline A. Lindemans
Published 2024-06-01

Nemo-like Kinase Drives Foxp3 Stability and Is Critical for Maintenance of Immune Tolerance by Regulatory T Cells

by Veerle Fleskens, Carlos M. Minutti, Xingmei Wu, Ping Wei, Cornelieke E.G.M. Pals, James McCrae, Saskia Hemmers, Vincent Groenewold, Harm-Jan Vos, Alexander Rudensky, Fan Pan, Huabin Li, Dietmar M. Zaiss, Paul J. Coffer
Published 2019-03-01

Inhibition of Super-Enhancer Activity in Autoinflammatory Site-Derived T Cells Reduces Disease-Associated Gene Expression

by Janneke G.C. Peeters, Stephin J. Vervoort, Sander C. Tan, Gerdien Mijnheer, Sytze de Roock, Sebastiaan J. Vastert, Edward E.S. Nieuwenhuis, Femke van Wijk, Berent J. Prakken, Menno P. Creyghton, Paul J. Coffer, Michal Mokry, Jorg van Loosdregt
Published 2015-09-01