Mechanistic Studies with DNA Polymerases Reveal Complex Outcomes following Bypass of DNA Damage

by Robert L. Eoff, Jeong-Yun Choi, F. Peter Guengerich
Published 2010-01-01

A Facile Semisynthesis and Evaluation of Garcinoic Acid and Its Analogs for the Inhibition of Human DNA Polymerase β

by Satheesh Gujarathi, Maroof Khan Zafar, Xingui Liu, Robert L. Eoff, Guangrong Zheng
Published 2020-12-01

A comprehensive strategy to discover inhibitors of the translesion synthesis DNA polymerase κ.

by Kinrin Yamanaka, Dorjbal Dorjsuren, Robert L Eoff, Martin Egli, David J Maloney, Ajit Jadhav, Anton Simeonov, R Stephen Lloyd
Published 2012-01-01

Mechanism of nucleic acid unwinding by SARS-CoV helicase.

by Adeyemi O Adedeji, Bruno Marchand, Aartjan J W Te Velthuis, Eric J Snijder, Susan Weiss, Robert L Eoff, Kamalendra Singh, Stefan G Sarafianos
Published 2012-01-01

323 Generation of a functional precision medicine pipeline which combines comparative transcriptomics and tumor organoid modeling to identify bespoke treatment strategies for gliob...

by Megan R. Reed, A. Geoffrey Lyle, Annick De Loose, Katrina Learned, Cecile Rose T. Vibat, Christopher P. Wardell, Robert L. Eoff, Olena M. Vaske, Analiz Rodriguez
Published 2022-04-01

Biobanked Glioblastoma Patient-Derived Organoids as a Precision Medicine Model to Study Inhibition of Invasion

by Emilie Darrigues, Edward H. Zhao, Annick De Loose, Madison P. Lee, Michael J. Borrelli, Robert L. Eoff, Deni S. Galileo, Narsimha R. Penthala, Peter A. Crooks, Analiz Rodriguez
Published 2021-10-01

Single and double modified salinomycin analogs target stem-like cells in 2D and 3D breast cancer models

by Alicja Urbaniak, Megan R. Reed, Daniel Fil, Anika Moorjani, Sarah Heflin, Michał Antoszczak, Michał Sulik, Adam Huczyński, Michalina Kupsik, Robert L. Eoff, Melanie C. MacNicol, Timothy C. Chambers, Angus M. MacNicol
Published 2021-09-01

Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer

by Alicja Urbaniak, Megan R. Reed, Billie Heflin, John Gaydos, Sergio Piña-Oviedo, Marta Jędrzejczyk, Greta Klejborowska, Natalia Stępczyńska, Timothy C. Chambers, Alan J. Tackett, Analiz Rodriguez, Adam Huczyński, Robert L. Eoff, Angus M. MacNicol
Published 2022-09-01

A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma

by Megan R. Reed, A. Geoffrey Lyle, Annick De Loose, Leena Maddukuri, Katrina Learned, Holly C. Beale, Ellen T. Kephart, Allison Cheney, Anouk van den Bout, Madison P. Lee, Kelsey N. Hundley, Ashley M. Smith, Teresa M. DesRochers, Cecile Rose T. Vibat, Murat Gokden, Sofie Salama, Christopher P. Wardell, Robert L. Eoff, Olena M. Vaske, Analiz Rodriguez
Published 2021-12-01