NCAPG Promotes Tumor Progression and Modulates Immune Cell Infiltration in Glioma

by Guangrong Zheng, Guangrong Zheng, Tao Han, Xiaomu Hu, Zhou Yang, Jin Wang, Zhenyi Wen, Hengyu Li, Hongjin Wang
Published 2022-03-01

Overcoming Cancer Drug Resistance Utilizing PROTAC Technology

by Matthew R. Burke, Alexis R. Smith, Guangrong Zheng
Published 2022-04-01

(2S,6S)-1-Methyl-2,6-trans-distyrylpiperidinium chloride

by Guangrong Zheng, Sean Parkin, Linda P. Dwoskin, Peter A. Crooks
Published 2010-01-01

1-Methyl-2,6-cis-distyrylpiperidine

by Guangrong Zheng, Sean Parkin, Linda P. Dwoskin, Peter A. Crooks
Published 2010-01-01

Concise Synthesis of (S)‑δ-CEHC, a Metabolite of Vitamin E

by Matthew Burke, Pratik Pal, Peiyi Zhang, Xuan Zhang, Guangrong Zheng
Published 2021-02-01

PROTACs are effective in addressing the platelet toxicity associated with BCL-XL inhibitors

by Peiyi Zhang, Xuan Zhang, Xingui Liu, Sajid Khan, Daohong Zhou, Guangrong Zheng
Published 2020-08-01

A Facile Semisynthesis and Evaluation of Garcinoic Acid and Its Analogs for the Inhibition of Human DNA Polymerase β

by Satheesh Gujarathi, Maroof Khan Zafar, Xingui Liu, Robert L. Eoff, Guangrong Zheng
Published 2020-12-01

Persistent fifth aortic arch: a comprehensive literature review

by Haiyan Shan, Xiaolan Du, Guangrong Zheng, Tengfei Ke, Chengde Liao, Haiyan Yang
Published 2023-06-01

The correlation between lateralization of intracerebral hemorrhage in basal ganglia and handedness

by Yu Cui, Zhenxing Zhang, Xiaochuan Huo, Jishou Dai, Guangrong Zheng, Xu Feng, Chao Wang
Published 2013-03-01

The correlation between lateralization of intracerebral hemorrhage in basal ganglia and handedness

by Yu Cui, Zhenxing Zhang, Xiaochuan Huo, Jishou Dai, Guangrong Zheng, Xu Feng, Chao Wang
Published 2013-03-01

PROTAC-Mediated Dual Degradation of BCL-xL and BCL-2 Is a Highly Effective Therapeutic Strategy in Small-Cell Lung Cancer

by Sajid Khan, Lin Cao, Janet Wiegand, Peiyi Zhang, Maria Zajac-Kaye, Frederic J. Kaye, Guangrong Zheng, Daohong Zhou
Published 2024-03-01

Publisher Correction: Factors associated with overdiagnosis of benign pulmonary nodules as malignancy: a retrospective cohort study

by Xirui Duan, Zhiqiang Ouyang, Shasha Bao, Lu Yang, Ailin Deng, Guangrong Zheng, Yu Zhu, Guochen Li, Jixiang Chu, Chengde Liao
Published 2023-12-01

Factors associated with overdiagnosis of benign pulmonary nodules as malignancy: a retrospective cohort study

by Xirui Duan, Zhiqiang Ouyang, Shasha Bao, Lu Yang, Ailin Deng, Guangrong Zheng, Yu Zhu, Guochen Li, Jixiang Chu, Chengde Liao
Published 2023-11-01

YAP at the Crossroads of Biomechanics and Drug Resistance in Human Cancer

by Miao Huang, Heyang Wang, Cole Mackey, Michael C. Chung, Juan Guan, Guangrong Zheng, Arkaprava Roy, Mingyi Xie, Christopher Vulpe, Xin Tang
Published 2023-08-01

Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies

by Yonghan He, Sajid Khan, Zhiguang Huo, Dongwen Lv, Xuan Zhang, Xingui Liu, Yaxia Yuan, Robert Hromas, Mingjiang Xu, Guangrong Zheng, Daohong Zhou
Published 2020-07-01

Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL

by Digant Nayak, Dongwen Lv, Yaxia Yuan, Peiyi Zhang, Wanyi Hu, Anindita Nayak, Eliza A. Ruben, Zongyang Lv, Patrick Sung, Robert Hromas, Guangrong Zheng, Daohong Zhou, Shaun K. Olsen
Published 2024-03-01

BCL-XL PROTAC degrader DT2216 synergizes with sotorasib in preclinical models of KRASG12C-mutated cancers

by Sajid Khan, Janet Wiegand, Peiyi Zhang, Wanyi Hu, Dinesh Thummuri, Vivekananda Budamagunta, Nan Hua, Lingtao Jin, Carmen J. Allegra, Scott E. Kopetz, Maria Zajac-Kaye, Frederic J. Kaye, Guangrong Zheng, Daohong Zhou
Published 2022-03-01

DT2216—a Bcl-xL-specific degrader is highly active against Bcl-xL-dependent T cell lymphomas

by Yonghan He, Raphael Koch, Vivekananda Budamagunta, Peiyi Zhang, Xuan Zhang, Sajid Khan, Dinesh Thummuri, Yuma T. Ortiz, Xin Zhang, Dongwen Lv, Janet S. Wiegand, Wen Li, Adam C. Palmer, Guangrong Zheng, David M. Weinstock, Daohong Zhou
Published 2020-07-01

Co-targeting BCL-XL and MCL-1 with DT2216 and AZD8055 synergistically inhibit small-cell lung cancer growth without causing on-target toxicities in mice

by Sajid Khan, Patrick Kellish, Nick Connis, Dinesh Thummuri, Janet Wiegand, Peiyi Zhang, Xuan Zhang, Vivekananda Budamagunta, Nan Hua, Yang Yang, Umasankar De, Lingtao Jin, Weizhou Zhang, Guangrong Zheng, Robert Hromas, Christine Hann, Maria Zajac-Kaye, Frederic J. Kaye, Daohong Zhou
Published 2023-01-01

Proteolysis-targeting chimera against BCL-XL destroys tumor-infiltrating regulatory T cells

by Ryan Kolb, Umasankar De, Sajid Khan, Yuewan Luo, Myung-Chul Kim, Haijun Yu, Chaoyan Wu, Jiao Mo, Xin Zhang, Peiyi Zhang, Xuan Zhang, Nicholas Borcherding, Daniel Koppel, Yang-Xin Fu, Song Guo Zheng, Dorina Avram, Guangrong Zheng, Daohong Zhou, Weizhou Zhang
Published 2021-02-01