Induction of Tolerance and Immunity by Dendritic Cells: Mechanisms and Clinical Applications

by Jitka Fucikova, Jitka Fucikova, Lenka Palova-Jelinkova, Lenka Palova-Jelinkova, Jirina Bartunkova, Jirina Bartunkova, Radek Spisek, Radek Spisek
Published 2019-10-01

Antigen Loading (e.g., Glutamic Acid Decarboxylase 65) of Tolerogenic DCs (tolDCs) Reduces Their Capacity to Prevent Diabetes in the Non-Obese Diabetes (NOD)-Severe Combined Immuno...

by David P. Funda, Jaroslav Goliáš, Tomáš Hudcovic, Hana Kozáková, Radek Špíšek, Radek Špíšek, Lenka Palová-Jelínková, Lenka Palová-Jelínková
Published 2018-02-01

Targeting tumor-associated macrophages for successful immunotherapy of ovarian carcinoma

by David Cibula, Iva Truxova, Radek Špíšek, Jitka Fucikova
Published 2023-02-01

Immunological configuration of ovarian carcinoma: features and impact on disease outcome

by Lorenzo Galluzzi, Radek Špíšek, Jitka Fucikova, Sandra Orsulic
Published 2021-10-01

Cell Based Therapy for Type 1 Diabetes: Should We Take Hyperglycemia Into Account?

by Anna Grohová, Anna Grohová, Anna Grohová, Klára Dáňová, Klára Dáňová, Radek Špíšek, Radek Špíšek, Lenka Palová-Jelínková, Lenka Palová-Jelínková
Published 2019-02-01

Optimal Tolerogenic Dendritic Cells in Type 1 Diabetes (T1D) Therapy: What Can We Learn From Non-obese Diabetic (NOD) Mouse Models?

by David P. Funda, Lenka Palová-Jelínková, Lenka Palová-Jelínková, Jaroslav Goliáš, Zuzana Kroulíková, Alena Fajstová, Tomáš Hudcovic, Radek Špíšek, Radek Špíšek
Published 2019-05-01

Calreticulin arms NK cells against leukemia

by Jitka Fucikova, Justin P. Kline, Lorenzo Galluzzi, Radek Spisek
Published 2020-01-01

Tumour devascularisation as a potential immunotherapeutic strategy

by Tomas Buchler, Pavel Vasek, Radek Spisek, Pavel Skrobanek, Vaclav Horejsi
Published 2019-01-01

Severe, but not mild heat-shock treatment induces immunogenic cell death in cancer cells

by Irena Adkins, Lenka Sadilkova, Nada Hradilova, Jakub Tomala, Marek Kovar, Radek Spisek
Published 2017-05-01

Immunological Network in Head and Neck Squamous Cell Carcinoma—A Prognostic Tool Beyond HPV Status

by Anna Fialová, Vladimír Koucký, Vladimír Koucký, Martina Hajdušková, Kamila Hladíková, Radek Špíšek
Published 2020-09-01

563 Pharmacodynamics and pharmacokinetics of SO-C101 in cynomolgus monkeys

by Ulrich Moebius, Radek Špíšek, David Béchard, Nada Podzimkova, Guy de Martynoff, Irena Adkins
Published 2020-11-01

Radiotherapy in Combination With Cytokine Treatment

by Ondrej Palata, Ondrej Palata, Nada Hradilova Podzimkova, Nada Hradilova Podzimkova, Eva Nedvedova, Alexandra Umprecht, Lenka Sadilkova, Lenka Palova Jelinkova, Lenka Palova Jelinkova, Radek Spisek, Radek Spisek, Irena Adkins, Irena Adkins
Published 2019-05-01

SOT101 induces NK cell cytotoxicity and potentiates antibody-dependent cell cytotoxicity and anti-tumor activity

by Zuzana Antosova, Nada Podzimkova, Nada Podzimkova, Jakub Tomala, Katerina Augustynkova, Katerina Sajnerova, Eva Nedvedova, Milada Sirova, Guy de Martynoff, David Bechard, Ulrich Moebius, Marek Kovar, Radek Spisek, Radek Spisek, Irena Adkins, Irena Adkins
Published 2022-10-01

Generation of dendritic cell-based vaccine using high hydrostatic pressure for non-small cell lung cancer immunotherapy.

by Nada Hradilova, Lenka Sadilkova, Ondrej Palata, Dagmar Mysikova, Hana Mrazkova, Robert Lischke, Radek Spisek, Irena Adkins
Published 2017-01-01

Trial watch: Peptide-based vaccines in anticancer therapy

by Lucillia Bezu, Oliver Kepp, Giulia Cerrato, Jonathan Pol, Jitka Fucikova, Radek Spisek, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi
Published 2018-12-01

Trial Watch: Toll-like receptor agonists in cancer immunotherapy

by Melody Smith, Elena García-Martínez, Michael R. Pitter, Jitka Fucikova, Radek Spisek, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi
Published 2018-12-01

Myeloid - derived suppressor cells in Type 1 diabetes are an expanded population exhibiting diverse T-cell suppressor mechanisms.

by Anna Grohová, Klára Dáňová, Irena Adkins, Zdeněk Šumník, Lenka Petruželková, Barbora Obermannová, Stanislava Koloušková, Radek Špíšek, Lenka Palová-Jelínková
Published 2020-01-01

Detection of immunogenic cell death and its relevance for cancer therapy

by Jitka Fucikova, Oliver Kepp, Lenka Kasikova, Giulia Petroni, Takahiro Yamazaki, Peng Liu, Liwei Zhao, Radek Spisek, Guido Kroemer, Lorenzo Galluzzi
Published 2020-11-01

Myeloid - derived suppressor cells in Type 1 diabetes are an expanded population exhibiting diverse T-cell suppressor mechanisms

by Anna Grohová, Klára Dáňová, Irena Adkins, Zdeněk Šumník, Lenka Petruželková, Barbora Obermannová, Stanislava Koloušková, Radek Špíšek, Lenka Palová-Jelínková, Veena Taneja
Published 2020-01-01

Trial watch: chemotherapy-induced immunogenic cell death in immuno-oncology

by Isaure Vanmeerbeek, Jenny Sprooten, Dirk De Ruysscher, Sabine Tejpar, Peter Vandenberghe, Jitka Fucikova, Radek Spisek, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi, Abhishek D. Garg
Published 2020-01-01