Induction of Tolerance and Immunity by Dendritic Cells: Mechanisms and Clinical Applications

by Jitka Fucikova, Jitka Fucikova, Lenka Palova-Jelinkova, Lenka Palova-Jelinkova, Jirina Bartunkova, Jirina Bartunkova, Radek Spisek, Radek Spisek
Published 2019-10-01

Antigen Loading (e.g., Glutamic Acid Decarboxylase 65) of Tolerogenic DCs (tolDCs) Reduces Their Capacity to Prevent Diabetes in the Non-Obese Diabetes (NOD)-Severe Combined Immuno...

by David P. Funda, Jaroslav Goliáš, Tomáš Hudcovic, Hana Kozáková, Radek Špíšek, Radek Špíšek, Lenka Palová-Jelínková, Lenka Palová-Jelínková
Published 2018-02-01

Cell Based Therapy for Type 1 Diabetes: Should We Take Hyperglycemia Into Account?

by Anna Grohová, Anna Grohová, Anna Grohová, Klára Dáňová, Klára Dáňová, Radek Špíšek, Radek Špíšek, Lenka Palová-Jelínková, Lenka Palová-Jelínková
Published 2019-02-01

Optimal Tolerogenic Dendritic Cells in Type 1 Diabetes (T1D) Therapy: What Can We Learn From Non-obese Diabetic (NOD) Mouse Models?

by David P. Funda, Lenka Palová-Jelínková, Lenka Palová-Jelínková, Jaroslav Goliáš, Zuzana Kroulíková, Alena Fajstová, Tomáš Hudcovic, Radek Špíšek, Radek Špíšek
Published 2019-05-01

Radiotherapy in Combination With Cytokine Treatment

by Ondrej Palata, Ondrej Palata, Nada Hradilova Podzimkova, Nada Hradilova Podzimkova, Eva Nedvedova, Alexandra Umprecht, Lenka Sadilkova, Lenka Palova Jelinkova, Lenka Palova Jelinkova, Radek Spisek, Radek Spisek, Irena Adkins, Irena Adkins
Published 2019-05-01

Myeloid - derived suppressor cells in Type 1 diabetes are an expanded population exhibiting diverse T-cell suppressor mechanisms.

by Anna Grohová, Klára Dáňová, Irena Adkins, Zdeněk Šumník, Lenka Petruželková, Barbora Obermannová, Stanislava Koloušková, Radek Špíšek, Lenka Palová-Jelínková
Published 2020-01-01

Data on microbial DNA-induced IL-1β production in monocytes of type 1 diabetes patients

by Irena Zentsova, Zuzana Parackova, Jana Kayserova, Lenka Palova-Jelinkova, Petra Vrabcova, Nikol Volfova, Zdenek Sumnik, Stepanka Pruhova, Lenka Petruzelkova, Anna Sediva
Published 2019-08-01

Myeloid - derived suppressor cells in Type 1 diabetes are an expanded population exhibiting diverse T-cell suppressor mechanisms

by Anna Grohová, Klára Dáňová, Irena Adkins, Zdeněk Šumník, Lenka Petruželková, Barbora Obermannová, Stanislava Koloušková, Radek Špíšek, Lenka Palová-Jelínková, Veena Taneja
Published 2020-01-01

815 Combination with IL-15Rβγ superagonist, Nanrilkefusp alfa, enhances CAR T and BOXR T cell anti-tumor activity

by Irena Adkins, Emily Kuiper, Kathleen Whiteman, Daniel Garafola, Pratirodh Koirala, Shannon Smith, Klara Danova, Ekaterina Simonova, Lenka Palova Jelinkova, Amy Jensen-Smith
Published 2023-11-01

Correction: Heat-Induced Structural Changes Affect OVA-Antigen Processing and Reduce Allergic Response in Mouse Model of Food Allergy.

by Jaroslav Golias, Martin Schwarzer, Michael Wallner, Miloslav Kverka, Hana Kozakova, Dagmar Srutkova, Klara Klimesova, Petr Sotkovsky, Lenka Palova-Jelinkova, Fatima Ferreira, Ludmila Tuckova
Published 2012-01-01

Heat-induced structural changes affect OVA-antigen processing and reduce allergic response in mouse model of food allergy.

by Jaroslav Golias, Martin Schwarzer, Michael Wallner, Miloslav Kverka, Hana Kozakova, Dagmar Srutkova, Klara Klimesova, Petr Sotkovsky, Lenka Palova-Jelinkova, Fatima Ferreira, Ludmila Tuckova
Published 2012-01-01

713 Nanrilkefusp alfa, a high-affinity IL-15Rβγ agonist, promotes an innate and adaptive anti-tumour inflammatory environment as single agent or combined with anti-PD-1 in patients...

by Ulrich Moebius, Radek Špíšek, David Béchard, Nada Podzimkova, Irena Adkins, Richard Sachse, Joachim Kiemle-Kallee, Ekaterina Simonova, Lenka Palova Jelinkova, Petr Danek, Martin Steegmaier
Published 2023-11-01

Pepsin digest of wheat gliadin fraction increases production of IL-1β via TLR4/MyD88/TRIF/MAPK/NF-κB signaling pathway and an NLRP3 inflammasome activation.

by Lenka Palová-Jelínková, Klára Dáňová, Hana Drašarová, Miloš Dvořák, David P Funda, Petra Fundová, Anna Kotrbová-Kozak, Marie Černá, Jana Kamanová, Stefan F Martin, Marina Freudenberg, Ludmila Tučková
Published 2013-01-01

1087 SOT201 is a novel cis-acting immunocytokine targeting IL-15Rβγ to reinvigorate PD-1+tumor infiltrating lymphocytes and potentiate anti-tumor efficacy

by Ulrich Moebius, Radek Špíšek, David Béchard, Zuzana Antosova, Nada Podzimkova, Irena Adkins, Klara Danova, Lenka Palova Jelinkova, Katerina Behalova, Petr Danek, Matej Fabisik, Kamila Hladikova, Nataliia Kalynovska, Lucie Kosinova, Pavel Marasek, Vladyslav Mazhara, Jan Praslicka, Katerina Sajnerova, Milada Sirova, Marek Kovar, Martin Steegmaier
Published 2023-11-01

Tissue contexture determines the pattern and density of tumor-infiltrating immune cells in HPV-associated squamous cell carcinomas of oropharynx and uterine cervix

by Lucie Pavelková, Eliška Táborská, Linn A. Syding, Klára Plačková, Ekaterina Simonova, Kamila Hladíková, Michal Hensler, Jan Laco, Vladimír Koucký, Michal Zábrodský, Jan Bouček, Marek Grega, Kateřina Rozkošová, Hana Vošmiková, Michael J. Halaška, Lukáš Rob, Ivan Práznovec, Miroslav Hodek, Milan Vošmik, Petr Čelakovský, Viktor Chrobok, Aleš Ryška, Lenka Palová-Jelínková, Radek Špíšek, Anna Fialová
Published 2024-03-01

Trial watch: chemotherapy-induced immunogenic cell death in oncology

by Jenny Sprooten, Raquel S. Laureano, Isaure Vanmeerbeek, Jannes Govaerts, Stefan Naulaerts, Daniel M. Borras, Lisa Kinget, Jitka Fucíková, Radek Špíšek, Lenka Palová Jelínková, Oliver Kepp, Guido Kroemer, Dmitri V. Krysko, An Coosemans, Rianne D.W. Vaes, Dirk De Ruysscher, Steven De Vleeschouwer, Els Wauters, Evelien Smits, Sabine Tejpar, Benoit Beuselinck, Sigrid Hatse, Hans Wildiers, Paul M. Clement, Peter Vandenabeele, Laurence Zitvogel, Abhishek D. Garg
Published 2023-12-01