BSL2-compliant lethal mouse model of SARS-CoV-2 and variants of concern to evaluate therapeutics targeting the Spike protein

by Mohanraj Manangeeswaran, Derek D. C. Ireland, Seth G. Thacker, Ha-Na Lee, Logan Kelley-Baker, Aaron P. Lewkowicz, Paul W. Rothlauf, Paul W. Rothlauf, Marjorie Cornejo Pontelli, Louis-Marie Bloyet, Michael A. Eckhaus, Mirian I. Mendoza, Sean Whelan, Daniela Verthelyi
Published 2022-07-01

Noninvasive Immuno-PET Imaging of CD8+ T Cell Behavior in Influenza A Virus-Infected Mice

by Paul W. Rothlauf, Paul W. Rothlauf, Zeyang Li, Novalia Pishesha, Novalia Pishesha, Novalia Pishesha, Novalia Pishesha, Yushu Joy Xie, Andrew W. Woodham, Andrew W. Woodham, Djenet Bousbaine, Stephen C. Kolifrath, Vincent L. Verschoor, Vincent L. Verschoor, Hidde L. Ploegh, Hidde L. Ploegh
Published 2021-11-01

Saliva enhances infection of gingival fibroblasts by herpes simplex virus 1.

by Yi Zuo, J Charles Whitbeck, Gabriel J Haila, Abraham A Hakim, Paul W Rothlauf, Roselyn J Eisenberg, Gary H Cohen, Claude Krummenacher
Published 2019-01-01

Detection of Bourbon Virus-Specific Serum Neutralizing Antibodies in Human Serum in Missouri, USA

by Gayan Bamunuarachchi, Houda Harastani, Paul W. Rothlauf, Ya-nan Dai, Ali Ellebedy, Daved Fremont, Sean P. J. Whelan, David Wang, Adrianus C. M. Boon
Published 2022-06-01

A small molecule exerts selective antiviral activity by targeting the human cytomegalovirus nuclear egress complex.

by Han Chen, Ming F Lye, Christoph Gorgulla, Scott B Ficarro, Gregory D Cuny, David A Scott, Fan Wu, Paul W Rothlauf, Xiaoou Wang, Rosio Fernandez, Jean M Pesola, Sorin Draga, Jarrod A Marto, James M Hogle, Haribabu Arthanari, Donald M Coen
Published 2023-11-01

JIB-04 Has Broad-Spectrum Antiviral Activity and Inhibits SARS-CoV-2 Replication and Coronavirus Pathogenesis

by Juhee Son, Shimeng Huang, Qiru Zeng, Traci L. Bricker, James Brett Case, Jinzhu Zhou, Ruochen Zang, Zhuoming Liu, Xinjian Chang, Tamarand L. Darling, Jian Xu, Houda H. Harastani, Lu Chen, Maria Florencia Gomez Castro, Yongxiang Zhao, Hinissan P. Kohio, Gaopeng Hou, Baochao Fan, Beibei Niu, Rongli Guo, Paul W. Rothlauf, Adam L. Bailey, Xin Wang, Pei-Yong Shi, Elisabeth D. Martinez, Steven L. Brody, Sean P. J. Whelan, Michael S. Diamond, Adrianus C. M. Boon, Bin Li, Siyuan Ding
Published 2022-02-01

Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell

by Maritza Puray-Chavez, Kyle M. LaPak, Travis P. Schrank, Jennifer L. Elliott, Dhaval P. Bhatt, Megan J. Agajanian, Ria Jasuja, Dana Q. Lawson, Keanu Davis, Paul W. Rothlauf, Zhuoming Liu, Heejoon Jo, Nakyung Lee, Kasyap Tenneti, Jenna E. Eschbach, Christian Shema Mugisha, Emily M. Cousins, Erica W. Cloer, Hung R. Vuong, Laura A. VanBlargan, Adam L. Bailey, Pavlo Gilchuk, James E. Crowe, Jr., Michael S. Diamond, D. Neil Hayes, Sean P.J. Whelan, Amjad Horani, Steven L. Brody, Dennis Goldfarb, M. Ben Major, Sebla B. Kutluay
Published 2021-07-01

Longitudinal Study after Sputnik V Vaccination Shows Durable SARS-CoV-2 Neutralizing Antibodies and Reduced Viral Variant Escape to Neutralization over Time

by María M. Gonzalez Lopez Ledesma, Lautaro Sanchez, Diego S. Ojeda, Santiago Oviedo Rouco, Andrés H. Rossi, Augusto Varese, Ignacio Mazzitelli, Carla A. Pascuale, Esteban A. Miglietta, Pamela E. Rodríguez, Horacio M. Pallarés, Guadalupe S. Costa Navarro, Julio J. Caramelo, Paul W. Rothlauf, Zhuoming Liu, Louis-Marie Bloyet, Marjorie Cornejo Pontelli, Natali B. Rasetto, Shirley D. Wenker, Lila Y. Ramis, Magalí G. Bialer, María Jose de Leone, C. Esteban Hernando, Luciana Bianchimano, Antonella S. Ríos, María Soledad Treffinger Cienfuegos, Diana R. Rodriguez García, Yesica Longueira, Natalia Laufer, Diego Alvarez, Ana Ceballos, Valeria Ochoa, Cecilia Monzani, Gariela Turk, Melina Salvatori, Jorge Carradori, Katherine Prost, Alejandra Rima, Claudia Varela, Regina Ercole, Rosana I. Toro, Sebastian Gutierrez, Martín Zubieta, Dolores Acuña, Mercedes S. Nabaes Jodar, Carolina Torres, Laura Mojsiejczuk, Mariana Viegas, Pilar Velazquez, Clarisa Testa, Nicolas Kreplak, Marcelo Yanovsky, Sean Whelan, Jorge Geffner, Marina Pifano, Andrea V. Gamarnik
Published 2022-02-01