Zika (PRVABC59) Infection Is Associated with T cell Infiltration and Neurodegeneration in CNS of Immunocompetent Neonatal C57Bl/6 Mice.

by Mohanraj Manangeeswaran, Derek D C Ireland, Daniela Verthelyi
Published 2016-11-01

CpG Oligonucleotides Protect Mice From Alphavirus Encephalitis: Role of NK Cells, Interferons, and TNF

by Mohanraj Manangeeswaran, Aaron P. Lewkowicz, Tomer Israely, Derek D.C. Ireland, Daniela Verthelyi
Published 2020-02-01

IL-6 Impairs Vaccine Responses in Neonatal Mice

by Jiyeon Yang, Jiro Sakai, Shafiuddin Siddiqui, Robert C. Lee, Derek D. C. Ireland, Daniela Verthelyi, Mustafa Akkoyunlu
Published 2018-12-01

Detection of innate immune response modulating impurities (IIRMI) in therapeutic peptides and proteins: Impact of excipients

by Seth G. Thacker, Cheng Her, Logan Kelley-Baker, Derek D C. Ireland, Mohanraj Manangeeswaran, Eric S. Pang, Daniela Verthelyi
Published 2022-09-01

Neonatal Zika virus infection causes transient perineuronal net degradation

by Kaliroi Engel, Ha-Na Lee, Bhanu P. Tewari, Aaron P. Lewkowicz, Derek D. C. Ireland, Mohanraj Manangeeswaran, Daniela Verthelyi
Published 2023-07-01

Association of complement component 4 with neuroimmune abnormalities in the subventricular zone in schizophrenia and autism spectrum disorders

by Ta-Chung M. Mou, Malcolm V. Lane, Derek D.C. Ireland, Daniela Verthelyi, Leonardo H. Tonelli, Sarah M. Clark
Published 2022-10-01

RNase L mediated protection from virus induced demyelination.

by Derek D C Ireland, Stephen A Stohlman, David R Hinton, Parul Kapil, Robert H Silverman, Roscoe A Atkinson, Cornelia C Bergmann
Published 2009-10-01

NK cells require immune checkpoint receptor LILRB4/gp49B to control neurotropic Zika virus infections in mice

by Ha-Na Lee, Mohanraj Manangeeswaran, Aaron P. Lewkowicz, Kaliroi Engel, Monica Chowdhury, Mamatha Garige, Michael A. Eckhaus, Carole Sourbier, Derek D.C. Ireland, Daniela Verthelyi
Published 2022-02-01

Characterization of the therapeutic effect of antibodies targeting the Ebola glycoprotein using a novel BSL2-compliant rVSVΔG-EBOV-GP infection model

by Ha-Na Lee, Ian L. McWilliams, Aaron P. Lewkowicz, Kaliroi Engel, Derek D. C. Ireland, Logan Kelley-Baker, Seth Thacker, Pedro Piccardo, Mohanraj Manangeeswaran, Daniela Verthelyi
Published 2021-01-01

Pseudovirus rVSVΔG-ZEBOV-GP Infects Neurons in Retina and CNS, Causing Apoptosis and Neurodegeneration in Neonatal Mice

by Ian L. McWilliams, Jennifer L. Kielczewski, Derek D.C. Ireland, Jacob S. Sykes, Aaron P. Lewkowicz, Krishnamurthy Konduru, Biying C. Xu, Chi-Chao Chan, Rachel R. Caspi, Mohanraj Manangeeswaran, Daniela Verthelyi
Published 2019-02-01

Long-term persistence of infectious Zika virus: Inflammation and behavioral sequela in mice.

by Derek D C Ireland, Mohanraj Manangeeswaran, Aaron P Lewkowicz, Kaliroi Engel, Sarah M Clark, Adelle Laniyan, Jacob Sykes, Ha-Na Lee, Ian L McWilliams, Logan Kelley-Baker, Leonardo H Tonelli, Daniela Verthelyi
Published 2020-12-01

BSL2-compliant lethal mouse model of SARS-CoV-2 and variants of concern to evaluate therapeutics targeting the Spike protein

by Mohanraj Manangeeswaran, Derek D. C. Ireland, Seth G. Thacker, Ha-Na Lee, Logan Kelley-Baker, Aaron P. Lewkowicz, Paul W. Rothlauf, Paul W. Rothlauf, Marjorie Cornejo Pontelli, Louis-Marie Bloyet, Michael A. Eckhaus, Mirian I. Mendoza, Sean Whelan, Daniela Verthelyi
Published 2022-07-01

Ebola virus-induced eye sequelae: a murine model for evaluating glycoprotein-targeting therapeuticsResearch in context

by Ha-Na Lee, Biying Xu, Aaron P. Lewkowicz, Kaliroi Engel, Logan Kelley-Baker, Ian L. McWilliams, Derek D.C. Ireland, Jennifer L. Kielczewski, Jinbo Li, Robert N. Fariss, Mercedes M. Campos, Alina Baum, Christos Kyratsous, Kristen Pascal, Chi-Chao Chan, Rachel R. Caspi, Mohanraj Manangeeswaran, Daniela Verthelyi
Published 2024-06-01