Biosynthesis of the Pseudomonas aeruginosa Extracellular Polysaccharides, Alginate, Pel, and Psl.

by Michael J Franklin, David E Nivens, Joel T Weadge, P Lynne Howell, P Lynne Howell
Published 2011-08-01

The Matrix Revisited: Opening Night for the Pel Polysaccharide Across Eubacterial Kingdoms

by Gregory B Whitfield, P Lynne Howell
Published 2021-02-01

Deacetylated microbial biofilm exopolysaccharides: It pays to be positive.

by Hanna Ostapska, P Lynne Howell, Donald C Sheppard
Published 2018-12-01

The molecular mechanism of the type IVa pilus motors

by Matthew McCallum, Stephanie Tammam, Ahmad Khan, Lori L. Burrows, P. Lynne Howell
Published 2017-05-01

A systematic pipeline for classifying bacterial operons reveals the evolutionary landscape of biofilm machineries.

by Cedoljub Bundalovic-Torma, Gregory B Whitfield, Lindsey S Marmont, P Lynne Howell, John Parkinson
Published 2020-04-01

Galactosaminogalactan (GAG) and its multiple roles in Aspergillus pathogenesis

by Cornelia Speth, Günter Rambach, Cornelia Lass-Flörl, P. Lynne Howell, Donald C. Sheppard
Published 2019-01-01

Multiple conformations facilitate PilT function in the type IV pilus

by Matthew McCallum, Samir Benlekbir, Sheryl Nguyen, Stephanie Tammam, John L. Rubinstein, Lori L. Burrows, P. Lynne Howell
Published 2019-11-01

The Pel polysaccharide is predominantly composed of a dimeric repeat of α-1,4 linked galactosamine and N-acetylgalactosamine

by François Le Mauff, Erum Razvi, Courtney Reichhardt, Piyanka Sivarajah, Matthew R. Parsek, P. Lynne Howell, Donald C. Sheppard
Published 2022-05-01

Author Correction: The Pel polysaccharide is predominantly composed of a dimeric repeat of α-1,4 linked galactosamine and N-acetylgalactosamine

by François Le Mauff, Erum Razvi, Courtney Reichhardt, Piyanka Sivarajah, Matthew R. Parsek, P. Lynne Howell, Donald C. Sheppard
Published 2022-06-01

Distinct types of multicellular aggregates in Pseudomonas aeruginosa liquid cultures

by Gavin Melaugh, Vincent A. Martinez, Perrin Baker, Preston J. Hill, P. Lynne Howell, Daniel J. Wozniak, Rosalind J. Allen
Published 2023-07-01

The Type IVa Pilus Machinery Is Recruited to Sites of Future Cell Division

by Tyson Carter, Ryan N. C. Buensuceso, Stephanie Tammam, Ryan P. Lamers, Hanjeong Harvey, P. Lynne Howell, Lori L. Burrows
Published 2017-03-01

Discovery and characterization of a Gram-positive Pel polysaccharide biosynthetic gene cluster.

by Gregory B Whitfield, Lindsey S Marmont, Cedoljub Bundalovic-Torma, Erum Razvi, Elyse J Roach, Cezar M Khursigara, John Parkinson, P Lynne Howell
Published 2020-04-01

Reducing <named-content content-type="genus-species">Aspergillus fumigatus</named-content> Virulence through Targeted Dysregulation of the Conidiation Pathway

by James I. P. Stewart, Vinicius M. Fava, Joshua D. Kerkaert, Adithya S. Subramanian, Fabrice N. Gravelat, Melanie Lehoux, P. Lynne Howell, Robert A. Cramer, Donald C. Sheppard
Published 2020-02-01

In vitro characterization of the antivirulence target of Gram-positive pathogens, peptidoglycan O-acetyltransferase A (OatA).

by David Sychantha, Carys S Jones, Dustin J Little, Patrick J Moynihan, Howard Robinson, Nicola F Galley, David I Roper, Christopher G Dowson, P Lynne Howell, Anthony J Clarke
Published 2017-10-01

Co-Operative Biofilm Interactions between <i>Aspergillus fumigatus</i> and <i>Pseudomonas aeruginosa</i> through Secreted Galactosaminogalactan Exopolysaccharide

by Hanna Ostapska, François Le Mauff, Fabrice N. Gravelat, Brendan D. Snarr, Natalie C. Bamford, Jaime C. Van Loon, Geoffrey McKay, Dao Nguyen, P. Lynne Howell, Donald C. Sheppard
Published 2022-03-01

The TPR domain of PgaA is a multifunctional scaffold that binds PNAG and modulates PgaB-dependent polymer processing.

by Roland Pfoh, Adithya S Subramanian, Jingjing Huang, Dustin J Little, Adam Forman, Benjamin R DiFrancesco, Negar Balouchestani-Asli, Elena N Kitova, John S Klassen, Régis Pomès, Mark Nitz, P Lynne Howell
Published 2022-08-01

Bps polysaccharide of Bordetella pertussis resists antimicrobial peptides by functioning as a dual surface shield and decoy and converts Escherichia coli into a respiratory pathoge...

by Audra R Fullen, Jessica L Gutierrez-Ferman, Kacy S Yount, Cheraton F Love, Hyun G Choi, Mario A Vargas, Deepa Raju, Kara N Corps, P Lynne Howell, Purnima Dubey, Rajendar Deora
Published 2022-08-01

PgaB orthologues contain a glycoside hydrolase domain that cleaves deacetylated poly-β(1,6)-N-acetylglucosamine and can disrupt bacterial biofilms.

by Dustin J Little, Roland Pfoh, François Le Mauff, Natalie C Bamford, Christina Notte, Perrin Baker, Manita Guragain, Howard Robinson, Gerald B Pier, Mark Nitz, Rajendar Deora, Donald C Sheppard, P Lynne Howell
Published 2018-04-01

Structural and biochemical characterization of the exopolysaccharide deacetylase Agd3 required for Aspergillus fumigatus biofilm formation

by Natalie C. Bamford, François Le Mauff, Jaime C. Van Loon, Hanna Ostapska, Brendan D. Snarr, Yongzhen Zhang, Elena N. Kitova, John S. Klassen, Jeroen D. C. Codée, Donald C. Sheppard, P. Lynne Howell
Published 2020-05-01

<italic toggle="yes">Pseudomonas aeruginosa</italic> Alginate Overproduction Promotes Coexistence with <italic toggle="yes">Staphylococcus aureus</italic> in a Model of Cystic Fibr...

by Dominique H. Limoli, Gregory B. Whitfield, Tomoe Kitao, Melissa L. Ivey, Michael R. Davis, Nora Grahl, Deborah A. Hogan, Laurence G. Rahme, P. Lynne Howell, George A. O’Toole, Joanna B. Goldberg
Published 2017-05-01