The TPR domain of PgaA is a multifunctional scaffold that binds PNAG and modulates PgaB-dependent polymer processing.

by Roland Pfoh, Adithya S Subramanian, Jingjing Huang, Dustin J Little, Adam Forman, Benjamin R DiFrancesco, Negar Balouchestani-Asli, Elena N Kitova, John S Klassen, Régis Pomès, Mark Nitz, P Lynne Howell
Published 2022-08-01

Small Molecule Inhibition of an Exopolysaccharide Modification Enzyme is a Viable Strategy To Block Pseudomonas aeruginosa Pel Biofilm Formation

by Erum Razvi, Benjamin R. DiFrancesco, Gregory A. Wasney, Zachary A. Morrison, John Tam, Anick Auger, Perrin Baker, Noor Alnabelseya, Jacquelyn D. Rich, Piyanka Sivarajah, Gregory B. Whitfield, Joe J. Harrison, Roman A. Melnyk, Mark Nitz, P. Lynne Howell
Published 2023-06-01