The Matrix Revisited: Opening Night for the Pel Polysaccharide Across Eubacterial Kingdoms

by Gregory B Whitfield, P Lynne Howell
Published 2021-02-01

Enzymatic modifications of exopolysaccharides enhance bacterial persistence

by Gregory B. Whitfield, Lindsey S Marmont, Lynne eHowell
Published 2015-05-01

A systematic pipeline for classifying bacterial operons reveals the evolutionary landscape of biofilm machineries.

by Cedoljub Bundalovic-Torma, Gregory B Whitfield, Lindsey S Marmont, P Lynne Howell, John Parkinson
Published 2020-04-01

Discovery and characterization of a Gram-positive Pel polysaccharide biosynthetic gene cluster.

by Gregory B Whitfield, Lindsey S Marmont, Cedoljub Bundalovic-Torma, Erum Razvi, Elyse J Roach, Cezar M Khursigara, John Parkinson, P Lynne Howell
Published 2020-04-01

<italic toggle="yes">Pseudomonas aeruginosa</italic> Alginate Overproduction Promotes Coexistence with <italic toggle="yes">Staphylococcus aureus</italic> in a Model of Cystic Fibr...

by Dominique H. Limoli, Gregory B. Whitfield, Tomoe Kitao, Melissa L. Ivey, Michael R. Davis, Nora Grahl, Deborah A. Hogan, Laurence G. Rahme, P. Lynne Howell, George A. O’Toole, Joanna B. Goldberg
Published 2017-05-01

Structure of the AlgKX modification and secretion complex required for alginate production and biofilm attachment in Pseudomonas aeruginosa

by Andreea A. Gheorghita, Yancheng E. Li, Elena N. Kitova, Duong T. Bui, Roland Pfoh, Kristin E. Low, Gregory B. Whitfield, Marthe T. C. Walvoort, Qingju Zhang, Jeroen D. C. Codée, John S. Klassen, P. Lynne Howell
Published 2022-12-01

Small Molecule Inhibition of an Exopolysaccharide Modification Enzyme is a Viable Strategy To Block Pseudomonas aeruginosa Pel Biofilm Formation

by Erum Razvi, Benjamin R. DiFrancesco, Gregory A. Wasney, Zachary A. Morrison, John Tam, Anick Auger, Perrin Baker, Noor Alnabelseya, Jacquelyn D. Rich, Piyanka Sivarajah, Gregory B. Whitfield, Joe J. Harrison, Roman A. Melnyk, Mark Nitz, P. Lynne Howell
Published 2023-06-01

Glycoside hydrolase processing of the Pel polysaccharide alters biofilm biomechanics and Pseudomonas aeruginosa virulence

by Erum Razvi, Gregory B. Whitfield, Courtney Reichhardt, Julia E. Dreifus, Alexandra R. Willis, Oxana B. Gluscencova, Erin S. Gloag, Tarek S. Awad, Jacquelyn D. Rich, Daniel Passos da Silva, Whitney Bond, François Le Mauff, Donald C. Sheppard, Benjamin D. Hatton, Paul Stoodley, Aaron W. Reinke, Gabrielle L. Boulianne, Daniel J. Wozniak, Joe J. Harrison, Matthew R. Parsek, P. Lynne Howell
Published 2023-02-01