Identification of intergenerational epigenetic inheritance by whole genome DNA methylation analysis in trios

by Anna Díez-Villanueva, Berta Martín, Ferran Moratalla-Navarro, Francisco D. Morón-Duran, Iván Galván-Femenía, Mireia Obón-Santacana, Anna Carreras, Rafael de Cid, Miguel A. Peinado, Victor Moreno
Published 2023-12-01

Performance of a Shotgun Prediction Model for Colorectal Cancer When Using 16S rRNA Sequencing Data

by Elies Ramon, Mireia Obón-Santacana, Olfat Khannous-Lleiffe, Ester Saus, Toni Gabaldón, Elisabet Guinó, David Bars-Cortina, Gemma Ibáñez-Sanz, Lorena Rodríguez-Alonso, Alfredo Mata, Ana García-Rodríguez, Victor Moreno
Published 2024-01-01

Non-Lynch Familial and Early-Onset Colorectal Cancer Explained by Accumulation of Low-Risk Genetic Variants

by Pilar Mur, Nuria Bonifaci, Anna Díez-Villanueva, Elisabet Munté, Maria Henar Alonso, Mireia Obón-Santacana, Gemma Aiza, Matilde Navarro, Virginia Piñol, Joan Brunet, Ian Tomlinson, Gabriel Capellá, Victor Moreno, Laura Valle
Published 2021-07-01

Polygenic risk score across distinct colorectal cancer screening outcomes: from premalignant polyps to colorectal cancer

by Mireia Obón-Santacana, Anna Díez-Villanueva, Maria Henar Alonso, Gemma Ibáñez-Sanz, Elisabet Guinó, Ana López, Lorena Rodríguez-Alonso, Alfredo Mata, Ana García-Rodríguez, Andrés García Palomo, Antonio J. Molina, Montse Garcia, Gemma Binefa, Vicente Martín, Victor Moreno
Published 2021-11-01

Genetic Effects on Transcriptome Profiles in Colon Epithelium Provide Functional Insights for Genetic Risk LociSummary

by Virginia Díez-Obrero, Christopher H. Dampier, Ferran Moratalla-Navarro, Matthew Devall, Sarah J. Plummer, Anna Díez-Villanueva, Ulrike Peters, Stephanie Bien, Jeroen R. Huyghe, Anshul Kundaje, Gemma Ibáñez-Sanz, Elisabeth Guinó, Mireia Obón-Santacana, Robert Carreras-Torres, Graham Casey, Víctor Moreno
Published 2021-01-01

Relationship between the Risk of Gastric Cancer and Adherence to the Mediterranean Diet According to Different Estimators. MCC—Spain Study

by Laura Álvarez-Álvarez, Facundo Vitelli-Storelli, María Rubín-García, Nuria Aragonés, Eva Ardanaz, Gemma Castaño-Vinyals, Mireia Obón-Santacana, Trinidad Dierssen-Sotos, Dolores Salas-Trejo, Adonina Tardón, José Juan Jiménez Moleón, Juan Alguacil, María Dolores Chirlaque, Beatriz Pérez-Gómez, Marina Pollán, Manolis Kogevinas, Vicente Martín
Published 2021-10-01

Meta-Analysis and Validation of a Colorectal Cancer Risk Prediction Model Using Deep Sequenced Fecal Metagenomes

by Mireia Obón-Santacana, Joan Mas-Lloret, David Bars-Cortina, Lourdes Criado-Mesas, Robert Carreras-Torres, Anna Díez-Villanueva, Ferran Moratalla-Navarro, Elisabet Guinó, Gemma Ibáñez-Sanz, Lorena Rodríguez-Alonso, Núria Mulet-Margalef, Alfredo Mata, Ana García-Rodríguez, Eric J. Duell, Ville Nikolai Pimenoff, Victor Moreno
Published 2022-08-01

Meat Intake, Cooking Methods, Doneness Preferences and Risk of Gastric Adenocarcinoma in the MCC-Spain Study

by Elena Boldo, Nerea Fernández de Larrea, Marina Pollán, Vicente Martín, Mireia Obón-Santacana, Marcela Guevara, Gemma Castaño-Vinyals, Jose María Canga, Beatriz Pérez-Gómez, Inés Gómez-Acebo, Guillermo Fernández-Tardón, Mercedes Vanaclocha-Espi, Rocío Olmedo-Requena, Juan Alguacil, Maria Dolores Chirlaque, Manolis Kogevinas, Nuria Aragonés, Adela Castelló
Published 2022-11-01

Association between Polyphenol Intake and Gastric Cancer Risk by Anatomic and Histologic Subtypes: MCC-Spain

by María Rubín-García, Facundo Vitelli-Storelli, Antonio José Molina, Raúl Zamora-Ros, Nuria Aragonés, Eva Adarnaz, Gemma Castaño-Vinyals, Mireia Obón-Santacana, Inés Gómez-Acebo, Ana Molina-Barceló, Guillermo Fernández-Tardón, José J Jiménez-Moleón, Juan Alguacil, María Dolores Chirlaque, Estefanía Toledo, Beatriz Pérez-Gómez, Marina Pollán, Manolis Kogevinas, Vicente Martín
Published 2020-10-01

COLONOMICS - integrative omics data of one hundred paired normal-tumoral samples from colon cancer patients

by Anna Díez-Villanueva, Rebeca Sanz-Pamplona, Xavier Solé, David Cordero, Marta Crous-Bou, Elisabet Guinó, Adriana Lopez-Doriga, Antoni Berenguer, Susanna Aussó, Laia Paré-Brunet, Mireia Obón-Santacana, Ferran Moratalla-Navarro, Ramon Salazar, Xavier Sanjuan, Cristina Santos, Sebastiano Biondo, Virginia Diez-Obrero, Ainhoa Garcia-Serrano, Maria Henar Alonso, Robert Carreras-Torres, Adria Closa, Víctor Moreno
Published 2022-10-01

Author Correction: COLONOMICS - integrative omics data of one hundred paired normal-tumoral samples from colon cancer patients

by Anna Díez-Villanueva, Rebeca Sanz-Pamplona, Xavier Solé, David Cordero, Marta Crous-Bou, Elisabet Guinó, Adriana Lopez-Doriga, Antoni Berenguer, Susanna Aussó, Laia Paré-Brunet, Mireia Obón-Santacana, Ferran Moratalla-Navarro, Ramon Salazar, Xavier Sanjuan, Cristina Santos, Sebastiano Biondo, Virginia Diez-Obrero, Ainhoa Garcia-Serrano, Maria Henar Alonso, Robert Carreras-Torres, Adria Closa, Víctor Moreno
Published 2022-11-01

Association between Polyphenol Intake and Breast Cancer Risk by Menopausal and Hormone Receptor Status

by Facundo Vitelli-Storelli, Raul Zamora-Ros, Antonio J. Molina, Tania Fernández-Villa, Adela Castelló, Juan Pablo Barrio, Pilar Amiano, Eva Ardanaz, Mireia Obón-Santacana, Inés Gómez-Acebo, Guillermo Fernández-Tardón, Ana Molina-Barceló, Juan Alguacil, Rafael Marcos-Gragera, Emma Ruiz-Moreno, Manuela Pedraza, Leire Gil, Marcela Guevara, Gemma Castaño-Vinyals, Trinidad Dierssen-Sotos, Manolis Kogevinas, Nuria Aragonés, Vicente Martín
Published 2020-04-01

Smoking history and breast cancer risk by pathological subtype: MCC-Spain study

by Belén Peñalver-Argüeso, Esther García-Esquinas, Adela Castelló, Nerea Fernández de Larrea-Baz, Gemma Castaño-Vinyals, Pilar Amiano, Tania Fernández-Villa, Marcela Guevara, Guillermo Fernández-Tardón, Juan Alguacil, Mireia Obón-Santacana, Inés Gómez-Acebo, Marina Pinto-Carbó, Rafael Marcos-Gragera, Nuria Aragonés, Amaia Aizpurua, Vicente Martín-Sánchez, Eva Ardanaz, Trinidad Dierssen-Sotos, Jose Juan Jiménez-Moleón, Manolis Kogevinas, Marina Pollán, Beatriz Pérez-Gómez
Published 2023-11-01

Flavonoids and the Risk of Gastric Cancer: An Exploratory Case-Control Study in the MCC-Spain Study

by Facundo Vitelli Storelli, Antonio José Molina, Raul Zamora-Ros, Tania Fernández-Villa, Vasiliki Roussou, Dora Romaguera, Nuria Aragonés, Mireia Obón-Santacana, Marcela Guevara, Inés Gómez-Acebo, Guillermo Fernández-Tardón, Ana Molina-Barceló, Rocío Olmedo-Requena, Rocío Capelo, María Dolores Chirlaque, Beatriz Pérez-Gómez, Victor Moreno, Jesús Castilla, María Rubín-García, Marina Pollán, Manolis Kogevinas, Juan Pablo Barrio Lera, Vicente Martín
Published 2019-04-01

Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers: A mendelian randomization analysis.

by James Yarmolinsky, Virginia Díez-Obrero, Tom G Richardson, Marie Pigeyre, Jennifer Sjaarda, Guillaume Paré, Venexia M Walker, Emma E Vincent, Vanessa Y Tan, Mireia Obón-Santacana, Demetrius Albanes, Jochen Hampe, Andrea Gsur, Heather Hampel, Rish K Pai, Mark Jenkins, Steven Gallinger, Graham Casey, Wei Zheng, Christopher I Amos, International Lung Cancer Consortium, PRACTICAL consortium, MEGASTROKE consortium, George Davey Smith, Richard M Martin, Victor Moreno
Published 2022-02-01

Dietary Inflammatory Index, Dietary Non-Enzymatic Antioxidant Capacity, and Colorectal and Breast Cancer Risk (MCC-Spain Study)

by Mireia Obón-Santacana, Dora Romaguera, Esther Gracia-Lavedan, Amaia Molinuevo, Esther Molina-Montes, Nitin Shivappa, James R. Hebert, Adonina Tardón, Gemma Castaño-Vinyals, Ferran Moratalla, Elisabet Guinó, Rafael Marcos-Gragera, Mikel Azpiri, Leire Gil, Rocío Olmedo-Requena, Macarena Lozano-Lorca, Juan Alguacil, Tania Fernández-Villa, Vicente Martín, Antonio J Molina, María Ederra, Conchi Moreno-Iribas, Beatriz Perez, Nuria Aragonés, Adela Castello, José Mª Huerta, Trinidad Dierssen-Sotos, Inés Gómez-Acebo, Ana Molina-Barceló, Marina Pollán, Manolis Kogevinas, Victor Moreno, Pilar Amiano
Published 2019-06-01

Identifying colorectal cancer caused by biallelic MUTYH pathogenic variants using tumor mutational signatures

by Peter Georgeson, Tabitha A. Harrison, Bernard J. Pope, Syed H. Zaidi, Conghui Qu, Robert S. Steinfelder, Yi Lin, Jihoon E. Joo, Khalid Mahmood, Mark Clendenning, Romy Walker, Efrat L. Amitay, Sonja I. Berndt, Hermann Brenner, Peter T. Campbell, Yin Cao, Andrew T. Chan, Jenny Chang-Claude, Kimberly F. Doheny, David A. Drew, Jane C. Figueiredo, Amy J. French, Steven Gallinger, Marios Giannakis, Graham G. Giles, Andrea Gsur, Marc J. Gunter, Michael Hoffmeister, Li Hsu, Wen-Yi Huang, Paul Limburg, JoAnn E. Manson, Victor Moreno, Rami Nassir, Jonathan A. Nowak, Mireia Obón-Santacana, Shuji Ogino, Amanda I. Phipps, John D. Potter, Robert E. Schoen, Wei Sun, Amanda E. Toland, Quang M. Trinh, Tomotaka Ugai, Finlay A. Macrae, Christophe Rosty, Thomas J. Hudson, Mark A. Jenkins, Stephen N. Thibodeau, Ingrid M. Winship, Ulrike Peters, Daniel D. Buchanan
Published 2022-06-01

Body size and risk of colorectal cancer molecular defined subtypes and pathways: Mendelian randomization analysesResearch in context

by Nikos Papadimitriou, Conghui Qu, Tabitha A. Harrison, Alaina M. Bever, Richard M. Martin, Konstantinos K. Tsilidis, Polly A. Newcomb, Stephen N. Thibodeau, Christina C. Newton, Caroline Y. Um, Mireia Obón-Santacana, Victor Moreno, Hermann Brenner, Marko Mandic, Jenny Chang-Claude, Michael Hoffmeister, Andrew J. Pellatt, Robert E. Schoen, Sophia Harlid, Shuji Ogino, Tomotaka Ugai, Daniel D. Buchanan, Brigid M. Lynch, Stephen B. Gruber, Yin Cao, Li Hsu, Jeroen R. Huyghe, Yi Lin, Robert S. Steinfelder, Wei Sun, Bethany Van Guelpen, Syed H. Zaidi, Amanda E. Toland, Sonja I. Berndt, Wen-Yi Huang, Elom K. Aglago, David A. Drew, Amy J. French, Peter Georgeson, Marios Giannakis, Meredith Hullar, Johnathan A. Nowak, Claire E. Thomas, Loic Le Marchand, Iona Cheng, Steven Gallinger, Mark A. Jenkins, Marc J. Gunter, Peter T. Campbell, Ulrike Peters, Mingyang Song, Amanda I. Phipps, Neil Murphy
Published 2024-03-01

Genome-wide interaction study of dietary intake of fibre, fruits, and vegetables with risk of colorectal cancerResearch in context

by Nikos Papadimitriou, Andre Kim, Eric S. Kawaguchi, John Morrison, Virginia Diez-Obrero, Demetrius Albanes, Sonja I. Berndt, Stéphane Bézieau, Stephanie A. Bien, D Timothy Bishop, Emmanouil Bouras, Hermann Brenner, Daniel D. Buchanan, Peter T. Campbell, Robert Carreras-Torres, Andrew T. Chan, Jenny Chang-Claude, David V. Conti, Matthew A. Devall, Niki Dimou, David A. Drew, Stephen B. Gruber, Tabitha A. Harrison, Michael Hoffmeister, Jeroen R. Huyghe, Amit D. Joshi, Temitope O. Keku, Anshul Kundaje, Sébastien Küry, Loic Le Marchand, Juan Pablo Lewinger, Li Li, Brigid M. Lynch, Victor Moreno, Christina C. Newton, Mireia Obón-Santacana, Jennifer Ose, Andrew J. Pellatt, Anita R. Peoples, Elizabeth A. Platz, Conghui Qu, Gad Rennert, Edward Ruiz-Narvaez, Anna Shcherbina, Mariana C. Stern, Yu-Ru Su, Duncan C. Thomas, Claire E. Thomas, Yu Tian, Konstantinos K. Tsilidis, Cornelia M. Ulrich, Caroline Y. Um, Kala Visvanathan, Jun Wang, Emily White, Michael O. Woods, Stephanie L. Schmit, Finlay Macrae, John D. Potter, John L. Hopper, Ulrike Peters, Neil Murphy, Li Hsu, Marc J. Gunter, W. James Gauderman
Published 2024-06-01

Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes

by Zhishan Chen, Xingyi Guo, Ran Tao, Jeroen R. Huyghe, Philip J. Law, Ceres Fernandez-Rozadilla, Jie Ping, Guochong Jia, Jirong Long, Chao Li, Quanhu Shen, Yuhan Xie, Maria N. Timofeeva, Minta Thomas, Stephanie L. Schmit, Virginia Díez-Obrero, Matthew Devall, Ferran Moratalla-Navarro, Juan Fernandez-Tajes, Claire Palles, Kitty Sherwood, Sarah E. W. Briggs, Victoria Svinti, Kevin Donnelly, Susan M. Farrington, James Blackmur, Peter G. Vaughan-Shaw, Xiao-Ou Shu, Yingchang Lu, Peter Broderick, James Studd, Tabitha A. Harrison, David V. Conti, Fredrick R. Schumacher, Marilena Melas, Gad Rennert, Mireia Obón-Santacana, Vicente Martín-Sánchez, Jae Hwan Oh, Jeongseon Kim, Sun Ha Jee, Keum Ji Jung, Sun-Seog Kweon, Min-Ho Shin, Aesun Shin, Yoon-Ok Ahn, Dong-Hyun Kim, Isao Oze, Wanqing Wen, Keitaro Matsuo, Koichi Matsuda, Chizu Tanikawa, Zefang Ren, Yu-Tang Gao, Wei-Hua Jia, John L. Hopper, Mark A. Jenkins, Aung Ko Win, Rish K. Pai, Jane C. Figueiredo, Robert W. Haile, Steven Gallinger, Michael O. Woods, Polly A. Newcomb, David Duggan, Jeremy P. Cheadle, Richard Kaplan, Rachel Kerr, David Kerr, Iva Kirac, Jan Böhm, Jukka-Pekka Mecklin, Pekka Jousilahti, Paul Knekt, Lauri A. Aaltonen, Harri Rissanen, Eero Pukkala, Johan G. Eriksson, Tatiana Cajuso, Ulrika Hänninen, Johanna Kondelin, Kimmo Palin, Tomas Tanskanen, Laura Renkonen-Sinisalo, Satu Männistö, Demetrius Albanes, Stephanie J. Weinstein, Edward Ruiz-Narvaez, Julie R. Palmer, Daniel D. Buchanan, Elizabeth A. Platz, Kala Visvanathan, Cornelia M. Ulrich, Erin Siegel, Stefanie Brezina, Andrea Gsur, Peter T. Campbell, Jenny Chang-Claude, Michael Hoffmeister, Hermann Brenner, Martha L. Slattery, John D. Potter, Kostas K. Tsilidis, Matthias B. Schulze, Marc J. Gunter, Neil Murphy, Antoni Castells, Sergi Castellví-Bel, Leticia Moreira, Volker Arndt, Anna Shcherbina, D. Timothy Bishop, Graham G. Giles, Melissa C. Southey, Gregory E. Idos, Kevin J. McDonnell, Zomoroda Abu-Ful, Joel K. Greenson, Katerina Shulman, Flavio Lejbkowicz, Kenneth Offit, Yu-Ru Su, Robert Steinfelder, Temitope O. Keku, Bethany van Guelpen, Thomas J. Hudson, Heather Hampel, Rachel Pearlman, Sonja I. Berndt, Richard B. Hayes, Marie Elena Martinez, Sushma S. Thomas, Paul D. P. Pharoah, Susanna C. Larsson, Yun Yen, Heinz-Josef Lenz, Emily White, Li Li, Kimberly F. Doheny, Elizabeth Pugh, Tameka Shelford, Andrew T. Chan, Marcia Cruz-Correa, Annika Lindblom, David J. Hunter, Amit D. Joshi, Clemens Schafmayer, Peter C. Scacheri, Anshul Kundaje, Robert E. Schoen, Jochen Hampe, Zsofia K. Stadler, Pavel Vodicka, Ludmila Vodickova, Veronika Vymetalkova, Christopher K. Edlund, W. James Gauderman, David Shibata, Amanda Toland, Sanford Markowitz, Andre Kim, Stephen J. Chanock, Franzel van Duijnhoven, Edith J. M. Feskens, Lori C. Sakoda, Manuela Gago-Dominguez, Alicja Wolk, Barbara Pardini, Liesel M. FitzGerald, Soo Chin Lee, Shuji Ogino, Stephanie A. Bien, Charles Kooperberg, Christopher I. Li, Yi Lin, Ross Prentice, Conghui Qu, Stéphane Bézieau, Taiki Yamaji, Norie Sawada, Motoki Iwasaki, Loic Le Marchand, Anna H. Wu, Chenxu Qu, Caroline E. McNeil, Gerhard Coetzee, Caroline Hayward, Ian J. Deary, Sarah E. Harris, Evropi Theodoratou, Stuart Reid, Marion Walker, Li Yin Ooi, Ken S. Lau, Hongyu Zhao, Li Hsu, Qiuyin Cai, Malcolm G. Dunlop, Stephen B. Gruber, Richard S. Houlston, Victor Moreno, Graham Casey, Ulrike Peters, Ian Tomlinson, Wei Zheng
Published 2024-04-01