Insight into genetic, biological, and environmental determinants of sexual-dimorphism in type 2 diabetes and glucose-related traits

by Amel Lamri, Amel Lamri, Monica De Paoli, Monica De Paoli, Russell De Souza, Russell De Souza, Geoff Werstuck, Geoff Werstuck, Sonia Anand, Sonia Anand, Sonia Anand, Marie Pigeyre, Marie Pigeyre
Published 2022-11-01

Effects of lifelong testosterone exposure on health and disease using Mendelian randomization

by Pedrum Mohammadi-Shemirani, Michael Chong, Marie Pigeyre, Robert W Morton, Hertzel C Gerstein, Guillaume Paré
Published 2020-10-01

A method to estimate the contribution of rare coding variants to complex trait heritability

by Nazia Pathan, Wei Q. Deng, Matteo Di Scipio, Mohammad Khan, Shihong Mao, Robert W. Morton, Ricky Lali, Marie Pigeyre, Michael R. Chong, Guillaume Paré
Published 2024-02-01

Post-Bariatric Surgery Changes in Quinolinic and Xanthurenic Acid Concentrations Are Associated with Glucose Homeostasis.

by Marie Favennec, Benjamin Hennart, Marie Verbanck, Marie Pigeyre, Robert Caiazzo, Violeta Raverdy, Hélène Verkindt, Audrey Leloire, Gilles J Guillemin, Loïc Yengo, Delphine Allorge, Philippe Froguel, François Pattou, Odile Poulain-Godefroy
Published 2016-01-01

GWAS and ExWAS of blood mitochondrial DNA copy number identifies 71 loci and highlights a potential causal role in dementia

by Michael Chong, Pedrum Mohammadi-Shemirani, Nicolas Perrot, Walter Nelson, Robert Morton, Sukrit Narula, Ricky Lali, Irfan Khan, Mohammad Khan, Conor Judge, Tafadzwa Machipisa, Nathan Cawte, Martin O'Donnell, Marie Pigeyre, Loubna Akhabir, Guillaume Paré
Published 2022-01-01

Fine-mapping of retinal vascular complexity loci identifies Notch regulation as a shared mechanism with myocardial infarction outcomes

by Ana Villaplana-Velasco, Marie Pigeyre, Justin Engelmann, Konrad Rawlik, Oriol Canela-Xandri, Claire Tochel, Frida Lona-Durazo, Muthu Rama Krishnan Mookiah, Alex Doney, Esteban J. Parra, Emanuele Trucco, Tom MacGillivray, Kristiina Rannikmae, Albert Tenesa, Erola Pairo-Castineira, Miguel O. Bernabeu
Published 2023-05-01

Consistent cord blood DNA methylation signatures of gestational age between South Asian and white European cohorts

by Wei Q. Deng, Marie Pigeyre, Sandi M. Azab, Samantha L. Wilson, Natalie Campbell, Nathan Cawte, Katherine M. Morrison, Stephanie A. Atkinson, Padmaja Subbarao, Stuart E. Turvey, Theo J. Moraes, Piush Mandhane, Meghan B. Azad, Elinor Simons, Guillaume Pare, Sonia S. Anand
Published 2024-06-01

The circulating proteome and brain health: Mendelian randomisation and cross-sectional analyses

by Rosie M. Walker, Michael Chong, Nicolas Perrot, Marie Pigeyre, Danni A. Gadd, Aleks Stolicyn, Liu Shi, Archie Campbell, Xueyi Shen, Heather C. Whalley, Alejo Nevado-Holgado, Andrew M. McIntosh, Stefan Heitmeier, Sumathy Rangarajan, Martin O’Donnell, Eric E. Smith, Salim Yusuf, William N. Whiteley, Guillaume Paré
Published 2024-05-01

Rationale and design of ePPOP-ID: a multicenter randomized controlled trial using an electronic-personalized program for obesity in pregnancy to improve delivery

by Philippe Deruelle, Sophie Lelorain, Sylvie Deghilage, Emmanuelle Couturier, Elodie Guilbert, Paul Berveiller, Marie Victoire Sénat, Christophe Vayssière, Loïc Sentilhes, Franck Perrotin, Denis Gallot, Céline Chauleur, Nicolas Sananes, Emmanuel Roth, Dominique Luton, Marie Caputo, Elodie Lorio, Carla Chatelet, Julien Couster, Oumar Timbely, Muriel Doret-Dion, Alain Duhamel, Marie Pigeyre
Published 2020-10-01

Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers: A mendelian randomization analysis.

by James Yarmolinsky, Virginia Díez-Obrero, Tom G Richardson, Marie Pigeyre, Jennifer Sjaarda, Guillaume Paré, Venexia M Walker, Emma E Vincent, Vanessa Y Tan, Mireia Obón-Santacana, Demetrius Albanes, Jochen Hampe, Andrea Gsur, Heather Hampel, Rish K Pai, Mark Jenkins, Steven Gallinger, Graham Casey, Wei Zheng, Christopher I Amos, International Lung Cancer Consortium, PRACTICAL consortium, MEGASTROKE consortium, George Davey Smith, Richard M Martin, Victor Moreno
Published 2022-02-01

Genome-wide studies reveal factors associated with circulating uromodulin and its relationships to complex diseases

by Yong Li, Yurong Cheng, Francesco Consolato, Guglielmo Schiano, Michael R. Chong, Maik Pietzner, Ngoc Quynh H. Nguyen, Nora Scherer, Mary L. Biggs, Marcus E. Kleber, Stefan Haug, Burulça Göçmen, Marie Pigeyre, Peggy Sekula, Inga Steinbrenner, Pascal Schlosser, Christina B. Joseph, Jennifer A. Brody, Morgan E. Grams, Caroline Hayward, Ulla T. Schultheiss, Bernhard K. Krämer, Florian Kronenberg, Annette Peters, Jochen Seissler, Dominik Steubl, Cornelia Then, Matthias Wuttke, Winfried März, Kai-Uwe Eckardt, Christian Gieger, Eric Boerwinkle, Bruce M. Psaty, Josef Coresh, Peter J. Oefner, Guillaume Pare, Claudia Langenberg, Jürgen E. Scherberich, Bing Yu, Shreeram Akilesh, Olivier Devuyst, Luca Rampoldi, Anna Köttgen
Published 2022-05-01