Molecular biomarkers in gastro-esophageal cancer: recent developments, current trends and future directions

by Francesca Battaglin, Madiha Naseem, Alberto Puccini, Heinz-Josef Lenz
Published 2018-07-01

Molecular characteristics of BRCA1/2 and PALB2 mutations in pancreatic ductal adenocarcinoma

by Andrew Elliott, Francesca Battaglin, Heinz-Josef Lenz, Kai Zimmer, Chadi Nabhan, Clemens Feistritzer
Published 2020-12-01

Prevalence of <i>ARID1A</i> Mutations in Cell-Free Circulating Tumor DNA in a Cohort of 71,301 Patients and Association with Driver Co-Alterations

by Razelle Kurzrock, Charu Aggarwal, Caroline Weipert, Lesli Kiedrowski, Jonathan Riess, Heinz-Josef Lenz, David Gandara
Published 2022-09-01

Patient Care Satisfaction and Emergency Room Utilization among Young Adult Colorectal Cancer Survivors during the SARS-CoV-2 Pandemic: Lessons Learned

by Dalia Kagramanov, Kimberly A. Miller, Phuong Gallagher, David R. Freyer, Joel E. Milam, Heinz-Josef Lenz, Afsaneh Barzi
Published 2023-01-01

Reduced Tumor Size of Untreated Papillary Thyroid Carcinoma After Immune Checkpoint Inhibitor–Induced Thyroiditis

by Dennis H. Chen, MD, Heinz-Josef Lenz, MD, Melissa G. Lechner, MD/PhD, Trevor E. Angell, MD
Published 2023-09-01

Disparities among Black and Hispanic colorectal cancer patients: Findings from the California Cancer Registry

by Joel Sanchez Mendez, Ruoxuan Wang, Lihua Liu, Juanjuan Zhang, Stephanie L. Schmit, Jane Figueiredo, Heinz‐Josef Lenz, Mariana C. Stern
Published 2023-11-01

Clinical Significance of Circulating Tumor Cell Induced Epithelial-Mesenchymal Transition in Patients with Metastatic Colorectal Cancer by Single-Cell RNA-Sequencing

by Masahiro Kozuka, Francesca Battaglin, Priya Jayachandran, Jingyuan Wang, Hiroyuki Arai, Shivani Soni, Wu Zhang, Mitsuharu Hirai, Satoshi Matsusaka, Heinz-Josef Lenz
Published 2021-09-01

q-Diffusion leverages the full dimensionality of gene coexpression in single-cell transcriptomics

by Myrl G. Marmarelis, Russell Littman, Francesca Battaglin, Donna Niedzwiecki, Alan Venook, Jose-Luis Ambite, Aram Galstyan, Heinz-Josef Lenz, Greg Ver Steeg
Published 2024-04-01

VprBP directs epigenetic gene silencing through histone H2A phosphorylation in colon cancer

by Nikhil Baban Ghate, Sangnam Kim, Erin Spiller, Sungmin Kim, Yonghwan Shin, Suhn K. Rhie, Goar Smbatyan, Heinz‐Josef Lenz, Shannon M. Mumenthaler, Woojin An
Published 2021-10-01

A revised nomenclature for the lemur family of protein kinases

by Gábor M. Mórotz, Neil A. Bradbury, Oana Caluseriu, Shin-ichi Hisanaga, Christopher C. J. Miller, Agnieszka Swiatecka-Urban, Heinz-Josef Lenz, Stephen J. Moss, Georgios Giamas
Published 2024-01-01

Time from Diagnosis and Correlates of Health-Related Quality of Life among Young Adult Colorectal Cancer Survivors

by Kimberly A. Miller, Julia Stal, Phuong Gallagher, Zhen Weng, David R. Freyer, Jonathan N. Kaslander, Priscilla Marin, Heinz-Josef Lenz, Joel E. Milam, Lauren Govaerts, Afsaneh Barzi
Published 2021-08-01

Anti-EGFR Therapy Induces EGF Secretion by Cancer-Associated Fibroblasts to Confer Colorectal Cancer Chemoresistance

by Colleen M. Garvey, Roy Lau, Alyssa Sanchez, Ren X. Sun, Emma J. Fong, Michael E. Doche, Oscar Chen, Anthony Jusuf, Heinz-Josef Lenz, Brent Larson, Shannon M. Mumenthaler
Published 2020-05-01

Expression of Immuno-Oncologic Biomarkers Is Enriched in Colorectal Cancers and Other Solid Tumors Harboring the A59T Variant of <i>KRAS</i>

by Emil Lou, Joanne Xiu, Yasmine Baca, Andrew C. Nelson, Benjamin A. Weinberg, Muhammad Shaalan Beg, Mohamed E. Salem, Heinz-Josef Lenz, Philip Philip, Wafik S. El-Deiry, W. Michael Korn
Published 2021-05-01

Human colorectal cancer-on-chip model to study the microenvironmental influence on early metastatic spread

by Carly Strelez, Sujatha Chilakala, Kimya Ghaffarian, Roy Lau, Erin Spiller, Nolan Ung, Danielle Hixon, Ah Young Yoon, Ren X. Sun, Heinz-Josef Lenz, Jonathan E. Katz, Shannon M. Mumenthaler
Published 2021-05-01

Phosphorylation and stabilization of EZH2 by DCAF1/VprBP trigger aberrant gene silencing in colon cancer

by Nikhil B. Ghate, Sungmin Kim, Yonghwan Shin, Jinman Kim, Michael Doche, Scott Valena, Alan Situ, Sangnam Kim, Suhn K. Rhie, Heinz-Josef Lenz, Tobias S. Ulmer, Shannon M. Mumenthaler, Woojin An
Published 2023-04-01

Pan-cancer analysis of RNA expression of ANGIOTENSIN-I-CONVERTING ENZYME 2 reveals high variability and possible impact on COVID-19 clinical outcomes

by Andrew Elliott, Michelle Saul, Jia Zeng, John L. Marshall, Edward S. Kim, Misako Nagasaka, Heinz-Josef Lenz, Lee Schwartzberg, David Spetzler, Jim Abraham, Joanne Xiu, Phillip Stafford, W. Michael Korn
Published 2021-03-01

High thymidylate synthase gene expression predicts poor outcome after resection of hepatocellular carcinoma.

by David B Donner, Eric K Nakakura, Alan P Venook, Heinz-Josef Lenz, Wu Zhang, Jimee Hwang, Emily K Bergsland, Meng Hsun Lin, Kan Toriguchi, Ricardo J Antonia, Robert S Warren
Published 2019-01-01

Immunogenic cell death pathway polymorphisms for predicting oxaliplatin efficacy in metastatic colorectal cancer

by Chiara Cremolini, Fotios Loupakis, Alfredo Falcone, Francesca Battaglin, Heinz-Josef Lenz, Natsuko Kawanishi, Shivani Soni, Wu Zhang, Christoph Mancao, Bodour Salhia, Shannon M Mumenthaler, Daniel J Weisenberger, Gangning Liang, Joshua Millstein
Published 2020-07-01

Polymorphisms within Immune Regulatory Pathways Predict Cetuximab Efficacy and Survival in Metastatic Colorectal Cancer Patients

by Nico B. Volz, Diana L. Hanna, Sebastian Stintzing, Wu Zhang, Dongyun Yang, Shu Cao, Yan Ning, Satoshi Matsusaka, Yu Sunakawa, Martin D. Berger, Chiara Cremolini, Fotios Loupakis, Alfredo Falcone, Heinz-Josef Lenz
Published 2020-10-01

Prognostic utility of self‐reported sarcopenia (SARC‐F) in the Multiethnic Cohort

by Anna H. Wu, V. Wendy Setiawan, Unhee Lim, Chiu‐Cheng Tseng, Kami K. White, John Shepherd, Heinz Josef Lenz, Iona Cheng, Daniel O. Stram, Christopher Haiman, Lynne R. Wilkens, Loïc Le Marchand
Published 2022-04-01