Use of preclinical models to improve treatment of retinoblastoma.

by Michael A Dyer, Carlos Rodriguez-Galindo, Matthew W Wilson
Published 2005-10-01

Analysis of MDM2 and MDM4 single nucleotide polymorphisms, mRNA splicing and protein expression in retinoblastoma.

by Justina McEvoy, Anatoly Ulyanov, Rachel Brennan, Gang Wu, Stanley Pounds, Jinghui Zhang, Michael A Dyer
Published 2012-01-01

Identification of a modular super-enhancer in murine retinal development

by Victoria Honnell, Jackie L. Norrie, Anand G. Patel, Cody Ramirez, Jiakun Zhang, Yu-Hsuan Lai, Shibiao Wan, Michael A. Dyer
Published 2022-01-01

Methylation profiling reveals novel molecular classes of rhabdomyosarcoma

by Michael R. Clay, Anand Patel, Quynh Tran, Dale J. Hedges, Ti-Cheng Chang, Elizabeth Stewart, Greg Charville, Cynthia Cline, Michael A. Dyer, Brent A. Orr
Published 2021-11-01

TNF Counterbalances the Emergence of M2 Tumor Macrophages

by Franz Kratochvill, Geoffrey Neale, Jessica M. Haverkamp, Lee-Ann Van de Velde, Amber M. Smith, Daisuke Kawauchi, Justina McEvoy, Martine F. Roussel, Michael A. Dyer, Joseph E. Qualls, Peter J. Murray
Published 2015-09-01

Longitudinal NK cell kinetics and cytotoxicity in children with neuroblastoma enrolled in a clinical phase II trial

by David Cullins, Barbara Rooney, Natasha Sahr, April Sykes, Mary Beth McCarville, Sara M Federico, Amanda Sooter, William E Janssen, Gwendolyn Anthony, Michael A Dyer, Alberto S Pappo, Wing H Leung, Wayne L Furman
Published 2020-06-01

On the mechanism of action of SJ-172550 in inhibiting the interaction of MDM4 and p53.

by Michal Bista, Michal Bista, David Smithson, Aleksandra Pecak, Gabriella Salinas, Katarzyna Pustelny, Jaeki Min, Artur Pirog, Kristin Finch, Michal Zdzalik, Brett Waddell, Benedykt Wladyka, Sylwia Kedracka-Krok, Michael A Dyer, Grzegorz Dubin, R Kiplin Guy
Published 2012-01-01

Retinal Cell Type DNA Methylation and Histone Modifications Predict Reprogramming Efficiency and Retinogenesis in 3D Organoid Cultures

by Lu Wang, Daniel Hiler, Beisi Xu, Issam AlDiri, Xiang Chen, Xin Zhou, Lyra Griffiths, Marc Valentine, Abbas Shirinifard, András Sablauer, Suresh Thiagarajan, Marie-Elizabeth Barabas, Jiakun Zhang, Dianna Johnson, Sharon Frase, Michael A. Dyer
Published 2018-03-01

Retinoblastoma from human stem cell-derived retinal organoids

by Jackie L. Norrie, Anjana Nityanandam, Karen Lai, Xiang Chen, Matthew Wilson, Elizabeth Stewart, Lyra Griffiths, Hongjian Jin, Gang Wu, Brent Orr, Quynh Tran, Sariah Allen, Colleen Reilly, Xin Zhou, Jiakun Zhang, Kyle Newman, Dianna Johnson, Rachel Brennan, Michael A. Dyer
Published 2021-07-01

Preclinical models for neuroblastoma: establishing a baseline for treatment.

by Tal Teitz, Jennifer J Stanke, Sara Federico, Cori L Bradley, Rachel Brennan, Jiakun Zhang, Melissa D Johnson, Jan Sedlacik, Madoka Inoue, Ziwei M Zhang, Sharon Frase, Jerold E Rehg, Claudia M Hillenbrand, David Finkelstein, Christopher Calabrese, Michael A Dyer, Jill M Lahti
Published 2011-04-01

Pan-neuroblastoma analysis reveals age- and signature-associated driver alterations

by Samuel W. Brady, Yanling Liu, Xiaotu Ma, Alexander M. Gout, Kohei Hagiwara, Xin Zhou, Jian Wang, Michael Macias, Xiaolong Chen, John Easton, Heather L. Mulder, Michael Rusch, Lu Wang, Joy Nakitandwe, Shaohua Lei, Eric M. Davis, Arlene Naranjo, Cheng Cheng, John M. Maris, James R. Downing, Nai-Kong V. Cheung, Michael D. Hogarty, Michael A. Dyer, Jinghui Zhang
Published 2020-10-01

An integrated single-cell RNA-seq map of human neuroblastoma tumors and preclinical models uncovers divergent mesenchymal-like gene expression programs

by Richard H. Chapple, Xueying Liu, Sivaraman Natarajan, Margaret I. M. Alexander, Yuna Kim, Anand G. Patel, Christy W. LaFlamme, Min Pan, William C. Wright, Hyeong-Min Lee, Yinwen Zhang, Meifen Lu, Selene C. Koo, Courtney Long, John Harper, Chandra Savage, Melissa D. Johnson, Thomas Confer, Walter J. Akers, Michael A. Dyer, Heather Sheppard, John Easton, Paul Geeleher
Published 2024-06-01

Targeting the DNA Repair Pathway in Ewing Sarcoma

by Elizabeth Stewart, Ross Goshorn, Cori Bradley, Lyra M. Griffiths, Claudia Benavente, Nathaniel R. Twarog, Gregory M. Miller, William Caufield, Burgess B. Freeman III, Armita Bahrami, Alberto Pappo, Jianrong Wu, Amos Loh, Åsa Karlström, Chris Calabrese, Brittney Gordon, Lyudmila Tsurkan, M. Jason Hatfield, Philip M. Potter, Scott E. Snyder, Suresh Thiagarajan, Abbas Shirinifard, Andras Sablauer, Anang A. Shelat, Michael A. Dyer
Published 2014-11-01

Recurrent Somatic Structural Variations Contribute to Tumorigenesis in Pediatric Osteosarcoma

by Xiang Chen, Armita Bahrami, Alberto Pappo, John Easton, James Dalton, Erin Hedlund, David Ellison, Sheila Shurtleff, Gang Wu, Lei Wei, Matthew Parker, Michael Rusch, Panduka Nagahawatte, Jianrong Wu, Shenghua Mao, Kristy Boggs, Heather Mulder, Donald Yergeau, Charles Lu, Li Ding, Michael Edmonson, Chunxu Qu, Jianmin Wang, Yongjin Li, Fariba Navid, Najat C. Daw, Elaine R. Mardis, Richard K. Wilson, James R. Downing, Jinghui Zhang, Michael A. Dyer
Published 2014-04-01

The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma

by Min Pan, William C. Wright, Richard H. Chapple, Asif Zubair, Manbir Sandhu, Jake E. Batchelder, Brandt C. Huddle, Jonathan Low, Kaley B. Blankenship, Yingzhe Wang, Brittney Gordon, Payton Archer, Samuel W. Brady, Sivaraman Natarajan, Matthew J. Posgai, John Schuetz, Darcie Miller, Ravi Kalathur, Siquan Chen, Jon Patrick Connelly, M. Madan Babu, Michael A. Dyer, Shondra M. Pruett-Miller, Burgess B. Freeman, Taosheng Chen, Lucy A. Godley, Scott C. Blanchard, Elizabeth Stewart, John Easton, Paul Geeleher
Published 2021-11-01

Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors

by Elaine M. Oberlick, Matthew G. Rees, Brinton Seashore-Ludlow, Francisca Vazquez, Geoffrey M. Nelson, Neekesh V. Dharia, Barbara A. Weir, Aviad Tsherniak, Mahmoud Ghandi, John M. Krill-Burger, Robin M. Meyers, Xiaofeng Wang, Phil Montgomery, David E. Root, Jake M. Bieber, Sandi Radko, Jaime H. Cheah, C. Suk-Yee Hon, Alykhan F. Shamji, Paul A. Clemons, Peter J. Park, Michael A. Dyer, Todd R. Golub, Kimberly Stegmaier, William C. Hahn, Elizabeth A. Stewart, Stuart L. Schreiber, Charles W.M. Roberts
Published 2019-08-01

MYCN amplification and ATRX mutations are incompatible in neuroblastoma

by Maged Zeineldin, Sara Federico, Xiang Chen, Yiping Fan, Beisi Xu, Elizabeth Stewart, Xin Zhou, Jongrye Jeon, Lyra Griffiths, Rosa Nguyen, Jackie Norrie, John Easton, Heather Mulder, Donald Yergeau, Yanling Liu, Jianrong Wu, Collin Van Ryn, Arlene Naranjo, Michael D. Hogarty, Marcin M. Kamiński, Marc Valentine, Shondra M. Pruett-Miller, Alberto Pappo, Jinghui Zhang, Michael R. Clay, Armita Bahrami, Peter Vogel, Seungjae Lee, Anang Shelat, Jay F. Sarthy, Michael P. Meers, Rani E. George, Elaine R. Mardis, Richard K. Wilson, Steven Henikoff, James R. Downing, Michael A. Dyer
Published 2020-02-01

Ipilmumab and cranial radiation in metastatic melanoma patients: a case series and review

by Schoenfeld, Jonathan D., Mahadevan, Anand, Floyd, Scott R., Dyer, Michael A., Catalano, Paul J., Alexander, Brian M., McDermott, David F., Kaplan, Irving D.
Published 2016