Hepatotoxicity of Herbal Supplements Mediated by Modulation of Cytochrome P450

by Christopher Trent Brewer, Taosheng Chen
Published 2017-11-01

PXR variants: the impact on drug metabolism and therapeutic responses

by C. Trent Brewer, Taosheng Chen
Published 2016-09-01

Modulation of Xenobiotic Receptors by Steroids

by Delira Robbins, Monimoy Banerjee, Taosheng Chen
Published 2013-06-01

Structural perspectives of the CYP3A family and their small molecule modulators in drug metabolism

by William C. Wright, Jude Chenge, Taosheng Chen
Published 2019-12-01

Development of BODIPY FL VH032 as a High-Affinity and Selective von Hippel–Lindau E3 Ligase Fluorescent Probe and Its Application in a Time-Resolved Fluorescence Resonance Energy-T...

by Wenwei Lin, Yongtao Li, Lei Yang, Taosheng Chen
Published 2020-12-01

GUItars: a GUI tool for analysis of high-throughput RNA interference screening data.

by Asli N Goktug, Su Sien Ong, Taosheng Chen
Published 2012-01-01

Cyclin-dependent kinase 4 phosphorylates and positively regulates PAX3-FOXO1 in human alveolar rhabdomyosarcoma cells.

by Lingling Liu, Jing Wu, Su Sien Ong, Taosheng Chen
Published 2013-01-01

Regulation of Nuclear Receptor Nur77 by miR-124.

by Alexa Tenga, Jordan A Beard, Apana Takwi, Yue-Ming Wang, Taosheng Chen
Published 2016-01-01

Design Space Exploration for YOLO Neural Network Accelerator

by Hongmin Huang, Zihao Liu, Taosheng Chen, Xianghong Hu, Qiming Zhang, Xiaoming Xiong
Published 2020-11-01

Efficient field‐programmable gate array‐based reconfigurable accelerator for deep convolution neural network

by Xianghong Hu, Taosheng Chen, Hongmin Huang, Zihao Liu, Xueming Li, Xiaoming Xiong
Published 2021-03-01

Toxicoproteomic Profiling of <i>hPXR</i> Transgenic Mice Treated with Rifampicin and Isoniazid

by Christopher Trent Brewer, Kiran Kodali, Jing Wu, Timothy I. Shaw, Junmin Peng, Taosheng Chen
Published 2020-07-01

Robust Classification of Small-Molecule Mechanism of Action Using a Minimalist High-Content Microscopy Screen and Multidimensional Phenotypic Trajectory Analysis.

by Nathaniel R Twarog, Jonathan A Low, Duane G Currier, Greg Miller, Taosheng Chen, Anang A Shelat
Published 2016-01-01

A protocol for high-throughput screening of histone lysine demethylase 4 inhibitors using TR-FRET assay

by Qiong Wu, Wenwei Lin, Zhen-Mei Li, Zoran Rankovic, Stephen W. White, Taosheng Chen, Jun Yang
Published 2021-09-01

A high-content screen of FDA approved drugs to enhance CAR T cell function: ingenol-3-angelate improves B7-H3-CAR T cell activity by upregulating B7-H3 on the target cell surface v...

by Ha Won Lee, Carla O’Reilly, Alex N. Beckett, Duane G. Currier, Taosheng Chen, Christopher DeRenzo
Published 2024-04-01

A high-throughput screening identifies histone deacetylase inhibitors as therapeutic agents against medulloblastoma

by Shanshan Zhang, Zhaojian Gong, Peter O. Oladimeji, Duane G. Currier, Qipan Deng, Ming Liu, Taosheng Chen, Yong Li
Published 2019-11-01

High-throughput screening reveals alsterpaullone, 2-cyanoethyl as a potent p27Kip1 transcriptional inhibitor.

by Brandon J Walters, Wenwei Lin, Shiyong Diao, Mark Brimble, Luigi I Iconaru, Jennifer Dearman, Asli Goktug, Taosheng Chen, Jian Zuo
Published 2014-01-01

The F-box-only protein 44 regulates pregnane X receptor protein level by ubiquitination and degradation

by Rebecca R. Florke Gee, Andrew D. Huber, Jing Wu, Richa Bajpai, Allister J. Loughran, Shondra M. Pruett-Miller, Taosheng Chen
Published 2023-11-01

SPA70 is a potent antagonist of human pregnane X receptor

by Wenwei Lin, Yue-Ming Wang, Sergio C. Chai, Lili Lv, Jie Zheng, Jing Wu, Qijun Zhang, Yong-Dong Wang, Patrick R. Griffin, Taosheng Chen
Published 2017-09-01

Transcription factor ZNF148 is a negative regulator of human muscle differentiation

by Jesse Bakke, William C. Wright, Anthony E. Zamora, Su Sien Ong, Yue-Ming Wang, Jessica D. Hoyer, Christopher T. Brewer, Paul G. Thomas, Taosheng Chen
Published 2017-08-01

Chemical manipulation of an activation/inhibition switch in the nuclear receptor PXR

by Efren Garcia-Maldonado, Andrew D. Huber, Sergio C. Chai, Stanley Nithianantham, Yongtao Li, Jing Wu, Shyaron Poudel, Darcie J. Miller, Jayaraman Seetharaman, Taosheng Chen
Published 2024-05-01