Targeted Therapy for Cutaneous Melanoma: Beyond BRAF...

by Michael A. Davies
Published 2014-01-01

1256 IL-1ß blockade mitigates immunotherapy-induced gut toxicity and promotes antitumor response

by Adi Diab, Yared Hailemichael, Noha Abdel-Wahab, Michael A Davies, Glenn Winn
Published 2023-11-01

48218 Preclinical modeling of BRAF(V600E)/PTEN-/- melanoma leptomeningeal disease (LMD) to assess intrathecal checkpoint blockade

by Renato A. Guerrieri, Grant M. Fischer, Barbara G. Knighton, Courtney W. Hudgens, Debora A. Ledesma, Michael A. Davies, Sherise D. Ferguson
Published 2021-03-01

Physical association of PDK1 with AKT1 is sufficient for pathway activation independent of membrane localization and phosphatidylinositol 3 kinase.

by Zhiyong Ding, Jiyong Liang, Jin Li, Yiling Lu, Vathsala Ariyaratna, Zhimin Lu, Michael A Davies, John K Westwick, Gordon B Mills
Published 2010-03-01

808 The CX3CL1-CX3CR1 chemokine axis can contribute to tumor immune evasion and blockade with a novel CX3CR1 monoclonal antibody enhances responses to anti-PD-1 immunotherapy

by Patrick Hwu, Apoorvi Chaudhri, Ping Hua, Xia Bu, Michael A Davies, Yunfei Wang, Shao-Hsi Hung, Ulrich Von Andrian, Gordon Freeman, Gregory A Lizee
Published 2023-11-01

High sensitivity sanger sequencing detection of BRAF mutations in metastatic melanoma FFPE tissue specimens

by Lauren Y. Cheng, Lauren E. Haydu, Ping Song, Jianyi Nie, Michael T. Tetzlaff, Lawrence N. Kwong, Jeffrey E. Gershenwald, Michael A. Davies, David Yu Zhang
Published 2021-04-01

Loss of AMPKα2 promotes melanoma tumor growth and brain metastasis

by Ping Yuan, Da Teng, Evelyn de Groot, Man Li, Sebastian Trousil, Che-Hung Shen, Jason Roszik, Michael A. Davies, Y.N. Vashisht Gopal, Bin Zheng
Published 2023-06-01

Bullous Pemphigoid-like Eruption Triggered by Targeted Therapy for Metastatic Melanoma

by Hanna Eriksson, Johan Hansson, Britta Krynitz, Giuseppe Masucci, Ada Girnita, Jan Lapins, Auris O. Huen, Hussein A. Tawbi, Michael A. Davies, Michael T. Tetzlaff, Jonathan L. Curry
Published 2020-11-01

The efficacy of anti‐programmed cell death protein 1 therapy among patients with metastatic acral and metastatic mucosal melanoma

by Dai Ogata, Lauren E. Haydu, Isabella C. Glitza, Sapna P. Patel, Hussein A. Tawbi, Jennifer L. McQuade, Adi Diab, Suhendan Ekmekcioglu, Michael K. Wong, Michael A. Davies, Rodabe N. Amaria
Published 2021-04-01

199 Quantitative and spatial characteristics of TIL in inflammatory neighborhoods of advanced melanoma tumors

by Adi Diab, Suhendan Ekmekcioglu, Noha Abdel-Wahab, Michael A Davies, Julie M Simon, Alexander J Lazar, Jared K Burks, Salah-Eddine Bentebibel, Sungnam Cho, Javier A Gomez, Reham Abdel-Wahab, Jeffrey E Gershenwald
Published 2023-11-01

AKT1 Activation Promotes Development of Melanoma Metastases

by Joseph H. Cho, James P. Robinson, Rowan A. Arave, William J. Burnett, David A. Kircher, Guo Chen, Michael A. Davies, Allie H. Grossmann, Matthew W. VanBrocklin, Martin McMahon, Sheri L. Holmen
Published 2015-11-01

iNOS Associates With Poor Survival in Melanoma: A Role for Nitric Oxide in the PI3K-AKT Pathway Stimulation and PTEN S-Nitrosylation

by Zhen Ding, Dai Ogata, Dai Ogata, Jason Roszik, Jason Roszik, Yong Qin, Yong Qin, Sun-Hee Kim, Michael T. Tetzlaff, Michael T. Tetzlaff, Alexander J. Lazar, Alexander J. Lazar, Michael A. Davies, Suhendan Ekmekcioglu, Elizabeth A. Grimm
Published 2021-02-01

Immune checkpoint inhibitor related myasthenia gravis: single center experience and systematic review of the literature

by Houssein Safa, Daniel H Johnson, Van Anh Trinh, Theresa E Rodgers, Heather Lin, Maria E Suarez-Almazor, Faisal Fa’ak, Chantal Saberian, Cassian Yee, Michael A Davies, Sudhakar Tummala, Karin Woodman, Noha Abdel-Wahab, Adi Diab
Published 2019-11-01

FOXD3 Regulates VISTA Expression in Melanoma

by Sheera R. Rosenbaum, Meghan Knecht, Mehri Mollaee, Zhijiu Zhong, Dan A. Erkes, Peter A. McCue, Inna Chervoneva, Adam C. Berger, Jennifer A. Lo, David E. Fisher, Jeffrey E. Gershenwald, Michael A. Davies, Timothy J. Purwin, Andrew E. Aplin
Published 2020-01-01

Comparative immunologic characterization of autoimmune giant cell myocarditis with ipilimumab

by Alexandre Reuben, Mariana Petaccia de Macedo, Jennifer McQuade, Aron Joon, Zhiyong Ren, Tiffany Calderone, Brandy Conner, Khalida Wani, Zachary A. Cooper, Hussein Tawbi, Michael T. Tetzlaff, Robert F. Padera, Jean-Bernard Durand, Alexander J. Lazar, Jennifer A. Wargo, Michael A. Davies
Published 2017-12-01

Mechanism-Specific Pharmacodynamics of a Novel Complex-I Inhibitor Quantified by Imaging Reversal of Consumptive Hypoxia with [¹⁸F]FAZA PET <i>In Vivo</i>

by Seth T. Gammon, Federica Pisaneschi, Madhavi L. Bandi, Melinda G. Smith, Yuting Sun, Yi Rao, Florian Muller, Franklin Wong, John De Groot, Jeffrey Ackroyd, Osama Mawlawi, Michael A. Davies, Y.N. Vashisht Gopal, M. Emilia Di Francesco, Joseph R. Marszalek, Mark Dewhirst, David Piwnica-Worms
Published 2019-11-01

Upregulation of cell surface GD3 ganglioside phenotype is associated with human melanoma brain metastasis

by Romela Irene Ramos, Matias A. Bustos, Jinfeng Wu, Peter Jones, Shu Ching Chang, Eiji Kiyohara, Kevin Tran, Xiaoqing Zhang, Stacey L. Stern, Sivan Izraely, Orit Sagi‐Assif, Isaac P. Witz, Michael A. Davies, Gordon B. Mills, Daniel F. Kelly, Reiko F. Irie, Dave S. B. Hoon
Published 2020-08-01

Clinical profiling of BCL-2 family members in the setting of BRAF inhibition offers a rationale for targeting de novo resistance using BH3 mimetics.

by Dennie T Frederick, Roberto A Salas Fragomeni, Aislyn Schalck, Isabel Ferreiro-Neira, Taylor Hoff, Zachary A Cooper, Rizwan Haq, David J Panka, Lawrence N Kwong, Michael A Davies, James C Cusack, Keith T Flaherty, David E Fisher, James W Mier, Jennifer A Wargo, Ryan J Sullivan
Published 2014-01-01

Co-Targeting FASN and mTOR Suppresses Uveal Melanoma Growth

by Anna Han, Dzmitry Mukha, Vivian Chua, Timothy J. Purwin, Manoela Tiago, Bhavik Modasia, Usman Baqai, Jenna L. Aumiller, Nelisa Bechtel, Emily Hunter, Meggie Danielson, Mizue Terai, Philip B. Wedegaertner, Takami Sato, Solange Landreville, Michael A. Davies, Stefan Kurtenbach, J. William Harbour, Zachary T. Schug, Andrew E. Aplin
Published 2023-06-01

Perspectives in melanoma: meeting report from the Melanoma Bridge (November 29th–1 December 1st, 2018, Naples, Italy)

by Paolo A. Ascierto, Sanjiv S. Agarwala, Gerardo Botti, Alfredo Budillon, Michael A. Davies, Reinhard Dummer, Marc Ernstoff, Soldano Ferrone, Silvia Formenti, Thomas F. Gajewski, Claus Garbe, Omid Hamid, Roger S. Lo, Jason J. Luke, Oliver Michielin, Giuseppe Palmieri, Laurence Zitvogel, Francesco M. Marincola, Giuseppe Masucci, Corrado Caracò, Magdalena Thurin, Igor Puzanov
Published 2019-07-01