Heterogeneity in the Metastatic Microenvironment: JunB-Expressing Microglia Cells as Potential Drivers of Melanoma Brain Metastasis Progression

by Orit Adir, Orit Sagi-Assif, Tsipi Meshel, Shlomit Ben-Menachem, Metsada Pasmanik-Chor, Dave S. B. Hoon, Isaac P. Witz, Sivan Izraely
Published 2023-10-01

Inter-Tumor Heterogeneity—Melanomas Respond Differently to GM-CSF-Mediated Activation

by Adi Moshe, Sivan Izraely, Orit Sagi-Assif, Sapir Malka, Shlomit Ben-Menachem, Tsipi Meshel, Metsada Pasmanik-Chor, Dave S.B. Hoon, Isaac P. Witz
Published 2020-07-01

Generation and Characterization of Novel Local and Metastatic Human Neuroblastoma Variants

by Ido Nevo, Orit Sagi-Assif, Liat Edry Botzer, Dana Amar, Shelly Maman, Naam Kariv, Leonor E. Leider-Trejo, Larissa Savelyeva, Manfred Schwab, Ilana Yron, Isaac P. Witz
Published 2008-08-01

The melanoma brain metastatic microenvironment: aldolase C partakes in shaping the malignant phenotype of melanoma cells – a case of inter‐tumor heterogeneity

by Sivan Izraely, Shlomit Ben‐Menachem, Orit Sagi‐Assif, Tsipi Meshel, Sapir Malka, Alona Telerman, Matias A. Bustos, Romela Irene Ramos, Metsada Pasmanik‐Chor, Dave S. B. Hoon, Isaac P. Witz
Published 2021-05-01

The Vicious Cycle of Melanoma-Microglia Crosstalk: Inter-Melanoma Variations in the Brain-Metastasis-Promoting IL-6/JAK/STAT3 Signaling Pathway

by Sivan Izraely, Shlomit Ben-Menachem, Sapir Malka, Orit Sagi-Assif, Matias A. Bustos, Orit Adir, Tsipi Meshel, Maharrish Chelladurai, Suyeon Ryu, Romela I. Ramos, Metsada Pasmanik-Chor, Dave S. B. Hoon, Isaac P. Witz
Published 2023-05-01

Regeneration Enhances Metastasis: A Novel Role for Neurovascular Signaling in Promoting Melanoma Brain Metastasis

by Roshini Prakash, Sivan Izraely, Nikita S. Thareja, Rex H. Lee, Maya Rappaport, Riki Kawaguchi, Orit Sagi-Assif, Shlomit Ben-Menachem, Tsipi Meshel, Michal Machnicki, Shuichi Ohe, Dave S. Hoon, Giovanni Coppola, Isaac P. Witz, S. Thomas Carmichael
Published 2019-04-01

Upregulation of cell surface GD3 ganglioside phenotype is associated with human melanoma brain metastasis

by Romela Irene Ramos, Matias A. Bustos, Jinfeng Wu, Peter Jones, Shu Ching Chang, Eiji Kiyohara, Kevin Tran, Xiaoqing Zhang, Stacey L. Stern, Sivan Izraely, Orit Sagi‐Assif, Isaac P. Witz, Michael A. Davies, Gordon B. Mills, Daniel F. Kelly, Reiko F. Irie, Dave S. B. Hoon
Published 2020-08-01