Recurrent histone mutations in T-cell acute lymphoblastic leukaemia.

by Collord, Grace, Martincorena, Inigo, Young, Matthew D, Foroni, Letizia, Bolli, Niccolo, Stratton, Michael R, Vassiliou, George S, Campbell, Peter J, Behjati, Sam
Published 2018

GOTHiC, a probabilistic model to resolve complex biases and to identify real interactions in Hi-C data.

by Mifsud, Borbala, Martincorena, Inigo, Darbo, Elodie, Sugar, Robert, Schoenfelder, Stefan, Fraser, Peter, Luscombe, Nicholas M
Published 2019

Comprehensive molecular characterization of mitochondrial genomes in human cancers.

by Yuan, Yuan, Ju, Young Seok, Kim, Youngwook, Li, Jun, Wang, Yumeng, Yoon, Christopher J, Yang, Yang, Martincorena, Inigo, Creighton, Chad J, Weinstein, John N, Xu, Yanxun, Han, Leng, Kim, Hyung-Lae, Nakagawa, Hidewaki, Park, Keunchil, Campbell, Peter J, Liang, Han, PCAWG Consortium
Published 2021

Somatic mutant clones colonize the human esophagus with age.

by Martincorena, Iñigo, Fowler, Joanna C, Wabik, Agnieszka, Lawson, Andrew RJ, Abascal, Federico, Hall, Michael WJ, Cagan, Alex, Murai, Kasumi, Mahbubani, Krishnaa, Stratton, Michael R, Fitzgerald, Rebecca C, Handford, Penny A, Campbell, Peter J, Saeb-Parsy, Kourosh, Jones, Philip H
Published 2018

Genomic evidence supports a clonal diaspora model for metastases of esophageal adenocarcinoma.

by Noorani, Ayesha, Li, Xiaodun, Goddard, Martin, Crawte, Jason, Alexandrov, Ludmil B, Secrier, Maria, Eldridge, Matthew D, Bower, Lawrence, Weaver, Jamie, Lao-Sirieix, Pierre, Martincorena, Inigo, Debiram-Beecham, Irene, Grehan, Nicola, MacRae, Shona, Malhotra, Shalini, Miremadi, Ahmad, Thomas, Tabitha, Galbraith, Sarah, Petersen, Lorraine, Preston, Stephen D, Gilligan, David, Hindmarsh, Andrew, Hardwick, Richard H, Stratton, Michael R, Wedge, David C, Fitzgerald, Rebecca C
Published 2019

Comprehensive molecular characterization of mitochondrial genomes in human cancers

by Yuan, Yuan, Ju, Young Seok, Kim, Youngwook, Li, Jun, Wang, Yumeng, Yoon, Christopher J., Yang, Yang, Martincorena, Inigo, Creighton, Chad J., Weinstein, John N., Xu, Yanxun, Han, Leng, Kim, Hyung-Lae, Nakagawa, Hidewaki, Park, Keunchil, Campbell, Peter J., Liang, Han
Published 2021

Increased somatic mutation burdens in normal human cells due to defective DNA polymerases.

by Robinson, Philip S, Coorens, Tim HH, Palles, Claire, Mitchell, Emily, Abascal, Federico, Olafsson, Sigurgeir, Lee, Bernard CH, Lawson, Andrew RJ, Lee-Six, Henry, Moore, Luiza, Sanders, Mathijs A, Hewinson, James, Martin, Lynn, Pinna, Claudia MA, Galavotti, Sara, Rahbari, Raheleh, Campbell, Peter J, Martincorena, Iñigo, Tomlinson, Ian, Stratton, Michael R
Published 2021

Somatic evolution and global expansion of an ancient transmissible cancer lineage

by Baez Ortega, Adrian, Gori, Kevin, Strakova, Andrea, Allen, Allum, Bansse-Issa, Bhutia, Bisson, Briceño, Castillo Domracheva, Corrigan, Cran, Crawford, Davis, de Castro, de Nardi, de Vos, Delgadillo Keenan, Donelan, Espinoza Huerta, Faramade, Fazil, Fotopoulou, Fruean, Gallardo-Arrieta, Glebova, Gouletsou, Häfelin Manrique, Henriques, Horta, Ignatenko, Kane, King, Koenig, Krupa, Kruzeniski, Kwon, Young Mi, Lanza-Perea, Lazyan, Lopez Quintana, Losfelt, Marino, Martínez Castañeda, Martínez-López, Meyer, Migneco, Nakanwagi, Neal, Neunzig, Ní Leathlobhair, Máire, Nixon, Ortega-Pacheco, Pedraza-Ordoñez, Peleteiro, Polak, Pye, Reece, Rojas Gutierrez, Sadia, Schmeling, Shamanova, Sherlock, Stammnitz, Maximilian, Steenland-Smit, Svitich, Tapia Martínez, Thoya Ngoka, Torres, Tudor, van der Wel, Vițălaru, Vural, Walkinton, Wang, Jinhong, Wehrle-Martinez, Widdowson, Stratton, Michael, Alexandrov, Ludmil, Martincorena, Iñigo, Murchison, Elizabeth
Published 2019

An integrated genomic analysis of anaplastic meningioma identifies prognostic molecular signatures.

by Collord, Grace, Tarpey, Patrick, Kurbatova, Natalja, Martincorena, Inigo, Moran, Sebastian, Castro, Manuel, Nagy, Tibor, Bignell, Graham, Maura, Francesco, Young, Matthew D, Berna, Jorge, Tubio, Jose MC, McMurran, Chris E, Young, Adam MH, Sanders, Mathijs, Noorani, Imran, Price, Stephen J, Watts, Colin, Leipnitz, Elke, Kirsch, Matthias, Schackert, Gabriele, Pearson, Danita, Devadass, Abel, Ram, Zvi, Collins, V Peter, Allinson, Kieren, Jenkinson, Michael D, Zakaria, Rasheed, Syed, Khaja, Hanemann, C Oliver, Dunn, Jemma, McDermott, Michael W, Kirollos, Ramez W, Vassiliou, George S, Esteller, Manel, Behjati, Sam, Brazma, Alvis, Santarius, Thomas, McDermott, Ultan
Published 2019

The landscape of somatic mutation in normal colorectal epithelial cells.

by Lee-Six, Henry, Olafsson, Sigurgeir, Ellis, Peter, Osborne, Robert J, Sanders, Mathijs A, Moore, Luiza, Georgakopoulos, Nikitas, Torrente, Franco, Noorani, Ayesha, Goddard, Martin, Robinson, Philip, Coorens, Tim HH, O'Neill, Laura, Alder, Christopher, Wang, Jingwei, Fitzgerald, Rebecca C, Zilbauer, Matthias, Coleman, Nicholas, Saeb-Parsy, Kourosh, Martincorena, Inigo, Campbell, Peter J, Stratton, Michael R
Published 2020

Mutational signatures are jointly shaped by DNA damage and repair.

by Volkova, Nadezda V, Meier, Bettina, González-Huici, Víctor, Bertolini, Simone, Gonzalez, Santiago, Vöhringer, Harald, Abascal, Federico, Martincorena, Iñigo, Campbell, Peter J, Gartner, Anton, Gerstung, Moritz
Published 2021

Mutational signatures are jointly shaped by DNA damage and repair

by Volkova, Nadezda V., Meier, Bettina, González-Huici, Víctor, Bertolini, Simone, Gonzalez, Santiago, Vöhringer, Harald, Abascal, Federico, Martincorena, Iñigo, Campbell, Peter J., Gartner, Anton, Gerstung, Moritz
Published 2020

Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition

by Alvarez, Eva G., Baez-Ortega, Adrian, Zamora, Jorge, Supek, Fran, Demeulemeester, Jonas, Santamarina, Martin, Temes, Javier, Garcia-Souto, Daniel, Detering, Harald, Li, Yilong, Rodriguez-Castro, Jorge, Dueso-Barroso, Ana, Bruzos, Alicia L., Dentro, Stefan C., Blanco, Miguel G., Contino, Gianmarco, Ardeljan, Daniel, Tojo, Marta, Zumalave, Sonia, Edwards, Paul A. W., Puiggròs, Montserrat, Chong, Zechen, Lee, Eunjung Alice, Raine, Keiran, Butler, Adam, Waszak, Sebastian M., Schumacher, Steven E., Monlong, Jean, Maura, Francesco, Bolli, Niccolo, Bourque, Guillaume, Gerstein, Mark, Wedge, David C., Beroukhim, Rameen, Torrents, David, Martincorena, Inigo, Fitzgerald, Rebecca C., Van Loo, Peter, Kazazian, Haig H., Tubio, Jose M. C., Akdemir, Kadir C., Boutros, Paul C., Bowtell, David D. L., Brors, Benedikt, Burns, Kathleen H., Campbell, Peter J., Chan, Kin, Chen, Ken, Cortés-Ciriano, Isidro, Dunford, Andrew J., Edwards, Paul A., Estivill, Xavier, Etemadmoghadam, Dariush, Feuerbach, Lars, Fink, J. Lynn, Frenkel-Morgenstern, Milana, Garsed, Dale W., Gordenin, Dmitry A., Haan, David, Haber, James E., Hess, Julian M., Hutter, Barbara, Imielinski, Marcin, Jones, David T. W., Ju, Young Seok, Kazanov, Marat D., Klimczak, Leszek J., Koh, Youngil, Korbel, Jan O., Kumar, Kiran, Lee, Jake June-Koo, Lynch, Andy G., Macintyre, Geoff, Markowetz, Florian, Martincorena, Iñigo, Martinez-Fundichely, Alexander, Meyerson, Matthew, Miyano, Satoru, Nakagawa, Hidewaki, Navarro, Fabio C. P., Ossowski, Stephan, Park, Peter J., Pearson, John V., Rippe, Karsten, Roberts, Nicola D., Roberts, Steven A., Rodriguez-Martin, Bernardo, Scully, Ralph, Shackleton, Mark, Sidiropoulos, Nikos, Sieverling, Lina, Stewart, Chip, Tubio, Jose M. C., Villasante, Izar, Waddell, Nicola, Wala, Jeremiah A., Weischenfeldt, Joachim, Yang, Lixing, Yao, Xiaotong, Yoon, Sung-Soo, Zhang, Cheng-Zhong
Published 2021

The Organization of Local and Distant Functional Connectivity in the Human Brain

by Sepulcre, Jorge, Liu, Hesheng, Talukdar, Tanveer, Martincorena, Iñigo, Yeo, Boon Thye Thomas, Buckner, Randy Lee
Published 2010

Somatic Evolution in Non-neoplastic IBD-Affected Colon.

by Olafsson, Sigurgeir, McIntyre, Rebecca E, Coorens, Tim, Butler, Timothy, Jung, Hyunchul, Robinson, Philip S, Lee-Six, Henry, Sanders, Mathijs A, Arestang, Kenneth, Dawson, Claire, Tripathi, Monika, Strongili, Konstantina, Hooks, Yvette, Stratton, Michael R, Parkes, Miles, Martincorena, Inigo, Raine, Tim, Campbell, Peter J, Anderson, Carl A
Published 2021

Increased somatic mutation burdens in normal human cells due to defective DNA polymerases

by Robinson, Philip S., Coorens, Tim H. H., Palles, Claire, Mitchell, Emily, Abascal, Federico, Olafsson, Sigurgeir, Lee, Bernard C. H., Lawson, Andrew R. J., Lee-Six, Henry, Moore, Luiza, Sanders, Mathijs A., Hewinson, James, Martin, Lynn, Pinna, Claudia M. A., Galavotti, Sara, Rahbari, Raheleh, Campbell, Peter J., Martincorena, Iñigo, Tomlinson, Ian, Stratton, Michael R.
Published 2021

Increased somatic mutation burdens in normal human cells due to defective DNA polymerases

by Robinson, Philip S., Coorens, Tim H. H., Palles, Claire, Mitchell, Emily, Abascal, Federico, Olafsson, Sigurgeir, Lee, Bernard C. H., Lawson, Andrew R. J., Lee-Six, Henry, Moore, Luiza, Sanders, Mathijs A., Hewinson, James, Martin, Lynn, Pinna, Claudia M. A., Galavotti, Sara, Rahbari, Raheleh, Campbell, Peter J., Martincorena, Iñigo, Tomlinson, Ian, Stratton, Michael R.
Published 2021

Mutational landscape of normal epithelial cells in Lynch Syndrome patients.

by Lee, Bernard CH, Robinson, Philip S, Coorens, Tim HH, Yan, Helen HN, Olafsson, Sigurgeir, Lee-Six, Henry, Sanders, Mathijs A, Siu, Hoi Cheong, Hewinson, James, Yue, Sarah SK, Tsui, Wai Yin, Chan, Annie SY, Chan, Anthony KW, Ho, Siu Lun, Campbell, Peter J, Martincorena, Inigo, Buczacki, Simon JA, Yuen, Siu Tsan, Leung, Suet Yi, Stratton, Michael R
Published 2022

Mutational landscape of normal epithelial cells in Lynch Syndrome patients.

by Lee, Bernard CH, Robinson, Philip S, Coorens, Tim HH, Yan, Helen HN, Olafsson, Sigurgeir, Lee-Six, Henry, Sanders, Mathijs A, Siu, Hoi Cheong, Hewinson, James, Yue, Sarah SK, Tsui, Wai Yin, Chan, Annie SY, Chan, Anthony KW, Ho, Siu Lun, Campbell, Peter J, Martincorena, Inigo, Buczacki, Simon JA, Yuen, Siu Tsan, Leung, Suet Yi, Stratton, Michael R
Published 2022

Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells.

by Robinson, Philip S, Thomas, Laura E, Abascal, Federico, Jung, Hyunchul, Harvey, Luke MR, West, Hannah D, Olafsson, Sigurgeir, Lee, Bernard CH, Coorens, Tim HH, Lee-Six, Henry, Butlin, Laura, Lander, Nicola, Truscott, Rebekah, Sanders, Mathijs A, Lensing, Stefanie V, Buczacki, Simon JA, Ten Hoopen, Rogier, Coleman, Nicholas, Brunton-Sim, Roxanne, Rushbrook, Simon, Saeb-Parsy, Kourosh, Lalloo, Fiona, Campbell, Peter J, Martincorena, Iñigo, Sampson, Julian R, Stratton, Michael R
Published 2022