Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells.

by Robinson, Philip S, Thomas, Laura E, Abascal, Federico, Jung, Hyunchul, Harvey, Luke MR, West, Hannah D, Olafsson, Sigurgeir, Lee, Bernard CH, Coorens, Tim HH, Lee-Six, Henry, Butlin, Laura, Lander, Nicola, Truscott, Rebekah, Sanders, Mathijs A, Lensing, Stefanie V, Buczacki, Simon JA, Ten Hoopen, Rogier, Coleman, Nicholas, Brunton-Sim, Roxanne, Rushbrook, Simon, Saeb-Parsy, Kourosh, Lalloo, Fiona, Campbell, Peter J, Martincorena, Iñigo, Sampson, Julian R, Stratton, Michael R
Published 2022

Somatic mutation rates scale with lifespan across mammals.

by Cagan, Alex, Baez-Ortega, Adrian, Brzozowska, Natalia, Abascal, Federico, Coorens, Tim HH, Sanders, Mathijs A, Lawson, Andrew RJ, Harvey, Luke MR, Bhosle, Shriram, Jones, David, Alcantara, Raul E, Butler, Timothy M, Hooks, Yvette, Roberts, Kirsty, Anderson, Elizabeth, Lunn, Sharna, Flach, Edmund, Spiro, Simon, Januszczak, Inez, Wrigglesworth, Ethan, Jenkins, Hannah, Dallas, Tilly, Masters, Nic, Perkins, Matthew W, Deaville, Robert, Druce, Megan, Bogeska, Ruzhica, Milsom, Michael D, Neumann, Björn, Gorman, Frank, Constantino-Casas, Fernando, Peachey, Laura, Bochynska, Diana, Smith, Ewan St John, Gerstung, Moritz, Campbell, Peter J, Murchison, Elizabeth P, Stratton, Michael R, Martincorena, Iñigo
Published 2022

Somatic mutation rates scale with lifespan across mammals.

by Cagan, Alex, Baez-Ortega, Adrian, Brzozowska, Natalia, Abascal, Federico, Coorens, Tim HH, Sanders, Mathijs A, Lawson, Andrew RJ, Harvey, Luke MR, Bhosle, Shriram, Jones, David, Alcantara, Raul E, Butler, Timothy M, Hooks, Yvette, Roberts, Kirsty, Anderson, Elizabeth, Lunn, Sharna, Flach, Edmund, Spiro, Simon, Januszczak, Inez, Wrigglesworth, Ethan, Jenkins, Hannah, Dallas, Tilly, Masters, Nic, Perkins, Matthew W, Deaville, Robert, Druce, Megan, Bogeska, Ruzhica, Milsom, Michael D, Neumann, Björn, Gorman, Frank, Constantino-Casas, Fernando, Peachey, Laura, Bochynska, Diana, Smith, Ewan, Gerstung, Moritz, Campbell, Peter J, Murchison, Elizabeth, Stratton, Michael R, Martincorena, Iñigo
Published 2022

Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells.

by Robinson, Philip S, Thomas, Laura E, Abascal, Federico, Jung, Hyunchul, Harvey, Luke MR, West, Hannah D, Olafsson, Sigurgeir, Lee, Bernard CH, Coorens, Tim HH, Lee-Six, Henry, Butlin, Laura, Lander, Nicola, Truscott, Rebekah, Sanders, Mathijs A, Lensing, Stefanie V, Buczacki, Simon JA, Ten Hoopen, Rogier, Coleman, Nicholas, Brunton-Sim, Roxanne, Rushbrook, Simon, Saeb-Parsy, Kourosh, Lalloo, Fiona, Campbell, Peter J, Martincorena, Iñigo, Sampson, Julian R, Stratton, Michael R
Published 2022

Somatic mutation rates scale with lifespan across mammals

by Cagan, Alex, Baez-Ortega, Adrian, Brzozowska, Natalia, Abascal, Federico, Coorens, Tim HH, Sanders, Mathijs A, Lawson, Andrew RJ, Harvey, Luke MR, Bhosle, Shriram, Jones, David, Alcantara, Raul E, Butler, Timothy M, Hooks, Yvette, Roberts, Kirsty, Anderson, Elizabeth, Lunn, Sharna, Flach, Edmund, Spiro, Simon, Januszczak, Inez, Wrigglesworth, Ethan, Jenkins, Hannah, Dallas, Tilly, Masters, Nic, Perkins, Matthew W, Deaville, Robert, Druce, Megan, Bogeska, Ruzhica, Milsom, Michael D, Neumann, Björn, Gorman, Frank, Constantino-Casas, Fernando, Peachey, Laura, Bochynska, Diana, Smith, Ewan St John, Gerstung, Moritz, Campbell, Peter J, Murchison, Elizabeth P, Stratton, Michael R, Martincorena, Iñigo
Published 2022

Somatic mutation landscapes at single-molecule resolution.

by Abascal, Federico, Harvey, Luke MR, Mitchell, Emily, Lawson, Andrew RJ, Lensing, Stefanie V, Ellis, Peter, Russell, Andrew JC, Alcantara, Raul E, Baez-Ortega, Adrian, Wang, Yichen, Kwa, Eugene Jing, Lee-Six, Henry, Cagan, Alex, Coorens, Tim HH, Chapman, Michael Spencer, Olafsson, Sigurgeir, Leonard, Steven, Jones, David, Machado, Heather E, Davies, Megan, Øbro, Nina F, Mahubani, Krishnaa T, Allinson, Kieren, Gerstung, Moritz, Saeb-Parsy, Kourosh, Kent, David G, Laurenti, Elisa, Stratton, Michael R, Rahbari, Raheleh, Campbell, Peter J, Osborne, Robert J, Martincorena, Iñigo
Published 2021