Somatic mutant clones colonize the human esophagus with age.

by Martincorena, Iñigo, Fowler, Joanna C, Wabik, Agnieszka, Lawson, Andrew RJ, Abascal, Federico, Hall, Michael WJ, Cagan, Alex, Murai, Kasumi, Mahbubani, Krishnaa, Stratton, Michael R, Fitzgerald, Rebecca C, Handford, Penny A, Campbell, Peter J, Saeb-Parsy, Kourosh, Jones, Philip H
Published 2018

Increased somatic mutation burdens in normal human cells due to defective DNA polymerases.

by Robinson, Philip S, Coorens, Tim HH, Palles, Claire, Mitchell, Emily, Abascal, Federico, Olafsson, Sigurgeir, Lee, Bernard CH, Lawson, Andrew RJ, Lee-Six, Henry, Moore, Luiza, Sanders, Mathijs A, Hewinson, James, Martin, Lynn, Pinna, Claudia MA, Galavotti, Sara, Rahbari, Raheleh, Campbell, Peter J, Martincorena, Iñigo, Tomlinson, Ian, Stratton, Michael R
Published 2021

Somatic mutation rates scale with lifespan across mammals.

by Cagan, Alex, Baez-Ortega, Adrian, Brzozowska, Natalia, Abascal, Federico, Coorens, Tim HH, Sanders, Mathijs A, Lawson, Andrew RJ, Harvey, Luke MR, Bhosle, Shriram, Jones, David, Alcantara, Raul E, Butler, Timothy M, Hooks, Yvette, Roberts, Kirsty, Anderson, Elizabeth, Lunn, Sharna, Flach, Edmund, Spiro, Simon, Januszczak, Inez, Wrigglesworth, Ethan, Jenkins, Hannah, Dallas, Tilly, Masters, Nic, Perkins, Matthew W, Deaville, Robert, Druce, Megan, Bogeska, Ruzhica, Milsom, Michael D, Neumann, Björn, Gorman, Frank, Constantino-Casas, Fernando, Peachey, Laura, Bochynska, Diana, Smith, Ewan St John, Gerstung, Moritz, Campbell, Peter J, Murchison, Elizabeth P, Stratton, Michael R, Martincorena, Iñigo
Published 2022

Somatic mutation rates scale with lifespan across mammals.

by Cagan, Alex, Baez-Ortega, Adrian, Brzozowska, Natalia, Abascal, Federico, Coorens, Tim HH, Sanders, Mathijs A, Lawson, Andrew RJ, Harvey, Luke MR, Bhosle, Shriram, Jones, David, Alcantara, Raul E, Butler, Timothy M, Hooks, Yvette, Roberts, Kirsty, Anderson, Elizabeth, Lunn, Sharna, Flach, Edmund, Spiro, Simon, Januszczak, Inez, Wrigglesworth, Ethan, Jenkins, Hannah, Dallas, Tilly, Masters, Nic, Perkins, Matthew W, Deaville, Robert, Druce, Megan, Bogeska, Ruzhica, Milsom, Michael D, Neumann, Björn, Gorman, Frank, Constantino-Casas, Fernando, Peachey, Laura, Bochynska, Diana, Smith, Ewan, Gerstung, Moritz, Campbell, Peter J, Murchison, Elizabeth, Stratton, Michael R, Martincorena, Iñigo
Published 2022

Somatic mutation rates scale with lifespan across mammals

by Cagan, Alex, Baez-Ortega, Adrian, Brzozowska, Natalia, Abascal, Federico, Coorens, Tim HH, Sanders, Mathijs A, Lawson, Andrew RJ, Harvey, Luke MR, Bhosle, Shriram, Jones, David, Alcantara, Raul E, Butler, Timothy M, Hooks, Yvette, Roberts, Kirsty, Anderson, Elizabeth, Lunn, Sharna, Flach, Edmund, Spiro, Simon, Januszczak, Inez, Wrigglesworth, Ethan, Jenkins, Hannah, Dallas, Tilly, Masters, Nic, Perkins, Matthew W, Deaville, Robert, Druce, Megan, Bogeska, Ruzhica, Milsom, Michael D, Neumann, Björn, Gorman, Frank, Constantino-Casas, Fernando, Peachey, Laura, Bochynska, Diana, Smith, Ewan St John, Gerstung, Moritz, Campbell, Peter J, Murchison, Elizabeth P, Stratton, Michael R, Martincorena, Iñigo
Published 2022

Development of a highly sensitive liquid biopsy platform to detect clinically-relevant cancer mutations at low allele fractions in cell-free DNA.

by Gale, Davina, Lawson, Andrew RJ, Howarth, Karen, Madi, Mikidache, Durham, Bradley, Smalley, Sarah, Calaway, John, Blais, Shannon, Jones, Greg, Clark, James, Dimitrov, Peter, Pugh, Michelle, Woodhouse, Samuel, Epstein, Michael, Fernandez-Gonzalez, Ana, Whale, Alexandra S, Huggett, Jim F, Foy, Carole A, Jones, Gerwyn M, Raveh-Amit, Hadas, Schmitt, Karin, Devonshire, Alison, Green, Emma, Forshew, Tim, Plagnol, Vincent, Rosenfeld, Nitzan
Published 2018

Somatic mutation landscapes at single-molecule resolution.

by Abascal, Federico, Harvey, Luke MR, Mitchell, Emily, Lawson, Andrew RJ, Lensing, Stefanie V, Ellis, Peter, Russell, Andrew JC, Alcantara, Raul E, Baez-Ortega, Adrian, Wang, Yichen, Kwa, Eugene Jing, Lee-Six, Henry, Cagan, Alex, Coorens, Tim HH, Chapman, Michael Spencer, Olafsson, Sigurgeir, Leonard, Steven, Jones, David, Machado, Heather E, Davies, Megan, Øbro, Nina F, Mahubani, Krishnaa T, Allinson, Kieren, Gerstung, Moritz, Saeb-Parsy, Kourosh, Kent, David G, Laurenti, Elisa, Stratton, Michael R, Rahbari, Raheleh, Campbell, Peter J, Osborne, Robert J, Martincorena, Iñigo
Published 2021

Patterns of within-host genetic diversity in SARS-CoV-2.

by Tonkin-Hill, Gerry, Martincorena, Inigo, Amato, Roberto, Lawson, Andrew Rj, Gerstung, Moritz, Johnston, Ian, Jackson, David K, Park, Naomi, Lensing, Stefanie V, Quail, Michael A, Gonçalves, Sónia, Ariani, Cristina, Spencer Chapman, Michael, Hamilton, William L, Meredith, Luke W, Hall, Grant, Jahun, Aminu S, Chaudhry, Yasmin, Hosmillo, Myra, Pinckert, Malte L, Georgana, Iliana, Yakovleva, Anna, Caller, Laura G, Caddy, Sarah L, Feltwell, Theresa, Khokhar, Fahad A, Houldcroft, Charlotte J, Curran, Martin D, Parmar, Surendra, Alderton, Alex, Nelson, Rachel, Harrison, Ewan M, Sillitoe, John, Bentley, Stephen D, Barrett, Jeffrey C, Torok, M Estee, Goodfellow, Ian G, Langford, Cordelia, Kwiatkowski, Dominic
Published 2021

Patterns of within-host genetic diversity in SARS-CoV-2

by Tonkin-Hill, Gerry, Martincorena, Inigo, Amato, Roberto, Lawson, Andrew RJ, Gerstrung, Moritz, Johnston, Ian, Jackson, David K, Park, Naomi, Lensing, Stefanie V, Quail, Michael A, Gonçalves, Sonia, Ariani, Cristina, Spencer Chapman, Michael, Hamilton, William L, Meredith, Luke W, Hall, Grant, Jahun, Aminu S, Chaudhry, Yasmin, Hosmillo, Myra, Pinckert, Malte L, Georgana, Iliana, Yakovleva, Anna, Caller, Laura G, Caddy, Sarah L, Feltwell, Theresa, Khokhar, Fahad A, Houldcroft, Charlotte J, Curran, Martin D, Parmar, Surendra, The COVID-19 Genomics UK (COG-UK) Consortium, Alderton, Alex, Nelson, Rachel, Harrison, Ewan M, Sillitoe, John, Bentley, Stephen D, Barrett, Jeffrey C, Torok, M Estee, Goodfellow, Ian G, Langford, Cordelia, Kwiatowski, Dominic P, Wellcome Sanger Institute COVID-19 Surveillance Team
Published 2021

Patterns of within-host genetic diversity in SARS-CoV-2.

by Tonkin-Hill, Gerry, Martincorena, Inigo, Amato, Roberto, Lawson, Andrew RJ, Gerstung, Moritz, Johnston, Ian, Jackson, David K, Park, Naomi, Lensing, Stefanie V, Quail, Michael A, Gonçalves, Sónia, Ariani, Cristina, Spencer Chapman, Michael, Hamilton, William L, Meredith, Luke W, Hall, Grant, Jahun, Aminu S, Chaudhry, Yasmin, Hosmillo, Myra, Pinckert, Malte L, Georgana, Iliana, Yakovleva, Anna, Caller, Laura G, Caddy, Sarah L, Feltwell, Theresa, Khokhar, Fahad A, Houldcroft, Charlotte J, Curran, Martin D, Parmar, Surendra, COVID-19 Genomics UK (COG-UK) Consortium, Alderton, Alex, Nelson, Rachel, Harrison, Ewan M, Sillitoe, John, Bentley, Stephen D, Barrett, Jeffrey C, Torok, M Estee, Goodfellow, Ian G, Langford, Cordelia, Kwiatkowski, Dominic, Wellcome Sanger Institute COVID-19 Surveillance Team
Published 2021