Application of personalised medicine to solid tumours: opportunities and challenges

by Christian Ruiz, Markus Tolnay, Lukas Bubendorf
Published 2012-06-01

Liquid Biopsy in Clinical Management of Breast, Lung, and Colorectal Cancer

by Ivana Bratić Hench, Jürgen Hench, Markus Tolnay
Published 2018-01-01

Dysregulated Interorganellar Crosstalk of Mitochondria in the Pathogenesis of Parkinson’s Disease

by Lara Sironi, Lisa Michelle Restelli, Markus Tolnay, Albert Neutzner, Stephan Frank
Published 2020-01-01

Functionally relevant domains of the prion protein identified in vivo.

by Frank Baumann, Jens Pahnke, Ivan Radovanovic, Thomas Rülicke, Juliane Bremer, Markus Tolnay, Adriano Aguzzi
Published 2009-09-01

Analysis of prion strains by PrPSc profiling in sporadic Creutzfeldt-Jakob disease.

by Gaby Schoch, Harald Seeger, Julien Bogousslavsky, Markus Tolnay, Robert Charles Janzer, Adriano Aguzzi, Markus Glatzel
Published 2006-02-01

A tissue-specific approach to the analysis of metabolic changes in Caenorhabditis elegans.

by Jürgen Hench, Ivana Bratić Hench, Claire Pujol, Sabine Ipsen, Susanne Brodesser, Arnaud Mourier, Markus Tolnay, Stephan Frank, Aleksandra Trifunović
Published 2011-01-01

Tau and neurofilaments in a family with frontotemporal dementia unlinked to chromosome 17q21–22

by Armand Savioz, Beat M Riederer, Peter Heutink, Patrizia Rizzu, Markus Tolnay, Enikö Kövari, Alphonse Probst, I.rène M Riederer, Constantin Bouras, Geneviève Leuba
Published 2003-02-01

Cerebrospinal fluid from Alzheimer’s disease patients promotes tau aggregation in transgenic mice

by Zhiva Skachokova, Alfonso Martinisi, Martin Flach, Frederik Sprenger, Yvonne Naegelin, Viviane Steiner-Monard, Marc Sollberger, Andreas U. Monsch, Michel Goedert, Markus Tolnay, David T. Winkler
Published 2019-05-01

Rapamycin attenuates the progression of tau pathology in P301S tau transgenic mice.

by Sefika Ozcelik, Graham Fraser, Perrine Castets, Véronique Schaeffer, Zhiva Skachokova, Karin Breu, Florence Clavaguera, Michael Sinnreich, Ludwig Kappos, Michel Goedert, Markus Tolnay, David Theo Winkler
Published 2013-01-01

Loss of NOTCH2 positively predicts survival in subgroups of human glial brain tumors.

by Jean-Louis Boulay, André R Miserez, Christian Zweifel, Balasubramanian Sivasankaran, Veronika Kana, Anthony Ghaffari, Cordelia Luyken, Michael Sabel, Abdessamad Zerrouqi, Morten Wasner, Erwin Van Meir, Markus Tolnay, Guido Reifenberger, Adrian Merlo
Published 2007-01-01

Neuronal Mitochondrial Dysfunction Activates the Integrated Stress Response to Induce Fibroblast Growth Factor 21

by Lisa Michelle Restelli, Björn Oettinghaus, Mark Halliday, Cavit Agca, Maria Licci, Lara Sironi, Claudia Savoia, Jürgen Hench, Markus Tolnay, Albert Neutzner, Alexander Schmidt, Anne Eckert, Giovanna Mallucci, Luca Scorrano, Stephan Frank
Published 2018-08-01

Analysis of AR/ARV7 Expression in Isolated Circulating Tumor Cells of Patients with Metastatic Castration-Resistant Prostate Cancer (SAKK 08/14 IMPROVE Trial)

by Ivana Bratic Hench, Richard Cathomas, Luigi Costa, Natalie Fischer, Silke Gillessen, Jürgen Hench, Thomas Hermanns, Eloïse Kremer, Walter Mingrone, Ricardo Pereira Mestre, Heike Püschel, Christian Rothermundt, Christian Ruiz, Markus Tolnay, Philippe Von Burg, Lukas Bubendorf, Tatjana Vlajnic
Published 2019-08-01

Two distinct immunopathological profiles in autopsy lungs of COVID-19

by Ronny Nienhold, Yari Ciani, Viktor H. Koelzer, Alexandar Tzankov, Jasmin D. Haslbauer, Thomas Menter, Nathalie Schwab, Maurice Henkel, Angela Frank, Veronika Zsikla, Niels Willi, Werner Kempf, Thomas Hoyler, Mattia Barbareschi, Holger Moch, Markus Tolnay, Gieri Cathomas, Francesca Demichelis, Tobias Junt, Kirsten D. Mertz
Published 2020-10-01

EpiDiP/NanoDiP: a versatile unsupervised machine learning edge computing platform for epigenomic tumour diagnostics

by Jürgen Hench, Claus Hultschig, Jon Brugger, Luigi Mariani, Raphael Guzman, Jehuda Soleman, Severina Leu, Miles Benton, Irenäus Maria Stec, Ivana Bratic Hench, Per Hoffmann, Patrick Harter, Katharina J Weber, Anne Albers, Christian Thomas, Martin Hasselblatt, Ulrich Schüller, Lisa Restelli, David Capper, Ekkehard Hewer, Joachim Diebold, Danijela Kolenc, Ulf C. Schneider, Elisabeth Rushing, Rosa della Monica, Lorenzo Chiariotti, Martin Sill, Daniel Schrimpf, Andreas von Deimling, Felix Sahm, Christian Kölsche, Markus Tolnay, Stephan Frank
Published 2024-04-01

Flower lose, a cell fitness marker, predicts COVID‐19 prognosis

by Michail Yekelchyk, Esha Madan, Jochen Wilhelm, Kirsty R Short, António M Palma, Linbu Liao, Denise Camacho, Everlyne Nkadori, Michael T Winters, Emily S Rice, Inês Rolim, Raquel Cruz‐Duarte, Christopher J Pelham, Masaki Nagane, Kartik Gupta, Sahil Chaudhary, Thomas Braun, Raghavendra Pillappa, Mark S Parker, Thomas Menter, Matthias Matter, Jasmin Dionne Haslbauer, Markus Tolnay, Kornelia D Galior, Kristina A Matkwoskyj, Stephanie M McGregor, Laura K Muller, Emad A Rakha, Antonio Lopez‐Beltran, Ronny Drapkin, Maximilian Ackermann, Paul B Fisher, Steven R Grossman, Andrew K Godwin, Arutha Kulasinghe, Ivan Martinez, Clay B Marsh, Benjamin Tang, Max S Wicha, Kyoung Jae Won, Alexandar Tzankov, Eduardo Moreno, Rajan Gogna
Published 2021-11-01