Clinical Trial Design for Testing the Stem Cell Model for the Prevention and Treatment of Cancer

by Max S. Wicha, Madhuri Kakarala, Rishindra M. Reddy
Published 2011-06-01

The Roles of the Let-7 Family of MicroRNAs in the Regulation of Cancer Stemness

by Yuxi Ma, Na Shen, Max S. Wicha, Ming Luo
Published 2021-09-01

Plasticity and Potency of Mammary Stem Cell Subsets During Mammary Gland Development

by Eunmi Lee, Raziye Piranlioglu, Max S. Wicha, Hasan Korkaya
Published 2019-05-01

Modeling of Cancer Stem Cell State Transitions Predicts Therapeutic Response.

by Mary E Sehl, Miki Shimada, Alfonso Landeros, Kenneth Lange, Max S Wicha
Published 2015-01-01

Biological and clinical significance of cancer stem cell plasticity

by Yongyou Zhu, Ming Luo, Michael Brooks, Shawn G Clouthier, Max S Wicha
Published 2014-12-01

Hybrid Stem Cell States: Insights Into the Relationship Between Mammary Development and Breast Cancer Using Single-Cell Transcriptomics

by Tasha Thong, Yutong Wang, Michael D. Brooks, Christopher T. Lee, Clayton Scott, Clayton Scott, Laura Balzano, Max S. Wicha, Max S. Wicha, Justin A. Colacino, Justin A. Colacino, Justin A. Colacino
Published 2020-05-01

A bcl-xS Adenovirus Selectively Induces Apoptosis in Transformed Cells Compared to Normal Mammary Cells

by Venil N. Sumantran, David S. Lee, Kathleen M. Woods Ignatoski, Stephen P. Ethiert, Max S. Wicha
Published 2000-05-01

4026 Dissecting the role of microenvironment heterogeneity on metastatic tumor cell phenotype at an engineered metastatic niche

by Sophia Orbach, Michael D. Brooks, Grace G. Bushnell, Max S. Wicha, Jacqueline S. Jeruss, Lonnie D. Shea
Published 2020-06-01

Cellular, transcriptomic and isoform heterogeneity of breast cancer cell line revealed by full-length single-cell RNA sequencing

by Shaocheng Wu, Hongjiu Zhang, Shamileh Fouladdel, Hongyang Li, Evan Keller, Max S. Wicha, Gilbert S. Omenn, Ebrahim Azizi, Yuanfang Guan
Published 2020-01-01

Regulation of mammary stem/progenitor cells by PTEN/Akt/beta-catenin signaling.

by Hasan Korkaya, Amanda Paulson, Emmanuelle Charafe-Jauffret, Christophe Ginestier, Marty Brown, Julie Dutcher, Shawn G Clouthier, Max S Wicha
Published 2009-06-01

A Dual‐Filtration System for Single‐Cell Sequencing of Circulating Tumor Cells and Clusters in HCC

by Vincent L. Chen, Qianhui Huang, Ramdane Harouaka, Yuheng Du, Anna S. Lok, Neehar D. Parikh, Lana X. Garmire, Max S. Wicha
Published 2022-06-01

Breast cancer dormancy: need for clinically relevant models to address current gaps in knowledge

by Grace G. Bushnell, Abhijeet P. Deshmukh, Petra den Hollander, Ming Luo, Rama Soundararajan, Dongya Jia, Herbert Levine, Sendurai A. Mani, Max S. Wicha
Published 2021-05-01

The BET degrader ZBC260 suppresses stemness and tumorigenesis and promotes differentiation in triple-negative breast cancer by disrupting inflammatory signaling

by Deeksha Sharma, Cody G. Hager, Li Shang, Lam Tran, Yongyou Zhu, Aihui Ma, Brian Magnuson, Matthew W. Lesko, Max S. Wicha, Monika L. Burness
Published 2023-11-01

Function of Integrin-Linked Kinase in Modulating the Stemness of IL-6–Abundant Breast Cancer Cells by Regulating γ-Secretase–Mediated Notch1 Activation in Caveolae

by En-Chi Hsu, Samuel K. Kulp, Han-Li Huang, Huang-Ju Tu, Santosh B. Salunke, Nicholas J. Sullivan, Duxin Sun, Max S. Wicha, Charles L. Shapiro, Ching-Shih Chen
Published 2015-06-01

Evaluation of STAT3 signaling in ALDH+ and ALDH+/CD44+/CD24- subpopulations of breast cancer cells.

by Li Lin, Brian Hutzen, Hsiu-Fang Lee, Zhengang Peng, Wenlong Wang, Chongqiang Zhao, Huey-Jen Lin, Duxin Sun, Pui-Kai Li, Chenglong Li, Hasan Korkaya, Max S Wicha, Jiayuh Lin
Published 2013-01-01

Hydro-Seq enables contamination-free high-throughput single-cell RNA-sequencing for circulating tumor cells

by Yu-Heng Cheng, Yu-Chih Chen, Eric Lin, Riley Brien, Seungwon Jung, Yu-Ting Chen, Woncheol Lee, Zhijian Hao, Saswat Sahoo, Hyun Min Kang, Jason Cong, Monika Burness, Sunitha Nagrath, Max S. Wicha, Euisik Yoon
Published 2019-05-01

Heterogeneity of Human Breast Stem and Progenitor Cells as Revealed by Transcriptional Profiling

by Justin A. Colacino, Ebrahim Azizi, Michael D. Brooks, Ramdane Harouaka, Shamileh Fouladdel, Sean P. McDermott, Michael Lee, David Hill, Julie Madden, Julie Boerner, Michele L. Cote, Maureen A. Sartor, Laura S. Rozek, Max S. Wicha
Published 2018-05-01

IL-6 Inhibition With MEDI5117 Decreases The Fraction of Head and Neck Cancer Stem Cells and Prevents Tumor Recurrence

by Kelsey A. Finkel, Kristy A. Warner, Samuel Kerk, Carol R. Bradford, Scott A. McLean, Mark E. Prince, Haihong Zhong, Elaine M. Hurt, Robert E. Hollingsworth, Max S. Wicha, David A. Tice, Jacques E. Nör
Published 2016-05-01

Primary tumor-induced immunity eradicates disseminated tumor cells in syngeneic mouse model

by Raziye Piranlioglu, EunMi Lee, Maria Ouzounova, Roni J. Bollag, Alicia H. Vinyard, Ali S. Arbab, Daniela Marasco, Mustafa Guzel, John K. Cowell, Muthushamy Thangaraju, Ahmed Chadli, Khaled A. Hassan, Max S. Wicha, Esteban Celis, Hasan Korkaya
Published 2019-03-01

High-Throughput Label-Free Isolation of Heterogeneous Circulating Tumor Cells and CTC Clusters from Non-Small-Cell Lung Cancer Patients

by Mina Zeinali, Maggie Lee, Arthi Nadhan, Anvya Mathur, Casey Hedman, Eric Lin, Ramdane Harouaka, Max S. Wicha, Lili Zhao, Nallasivam Palanisamy, Mathias Hafner, Rishindra Reddy, Gregory P. Kalemkerian, Bryan J. Schneider, Khaled A. Hassan, Nithya Ramnath, Sunitha Nagrath
Published 2020-01-01